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Original Articles

Cannabinoid Poisoning-Related Emergency Department Visits and Inpatient Hospitalizations in Kentucky, 2017 to 2019

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References

  • Azofeifa, A., Mattson, M., Schauer, G., McAfee, T., Grant, A., & Lyerla, R. (2016). National estimates of marijuana use and related indicators—National survey on drug use and health, United States, 2002–2014. Morbidity and Mortality Weekly Report. Surveillance Summaries (Washington, D.C.: 2002), 65(11), 1–28. https://doi.org/10.15585/mmwr.ss6511a1externalicon
  • Carliner, H., Brown, Q. L., Sarvet, A. L., & Hasin, D. S. (2017). Cannabis use, attitudes, and legal status in the U.S.: A review. Preventive Medicine, 104, 13–23.
  • Castañeda, C. P., Alliende, L. M., Iruretagoyena, B., Nachar, R., Mancilla, F., Díaz, C., Gallardo, C., Mena, C., Ramírez-Mahaluf, J. P., Undurraga, J., González-Valderrama, A., & Crossley, N. A. (2020). Cannabis use among hospitalized young people experiencing a first episode of psychosis: A case control study. Revista Medica de Chile, 148(11), 1606–1613.
  • CDC WONDER. (1999). 2019: Underlying cause of death by dridged-race catergories. https://wonder.cdc.gov/Deaths-by-Underlying-Cause.html
  • Centers for Disease Control & Prevention. (2018). Synthetic cannabinoids: An overview for healthcare providers. https://www.cdc.gov/nceh/hsb/chemicals/sc/healthcare.html#three
  • Chami, T., & Kim, C. H. (2019). Cannabis abuse and elevated risk of myocardial infarction in the young: A population-based study. Mayo clinic proceedings, 94(8), 1647–1649.
  • Chandra, S., Radwan, M. M., Majumdar, C. G., Church, J. C., Freeman, T. P., & ElSohly, M. A. (2019). New trends in cannabis potency in USA and Europe during the last decade (2008–2017). European Archives of Psychiatry and Clinical Neuroscience, 269(1), 5–15. https://doi.org/10.1007/s00406-019-00983-5
  • Cheng, P., Zagaran, A., Rajabali, F., Turcotte, K., & Babul, S. (2020). Setting the baseline: A description of cannabis poisonings at a Canadian pediatric hospital prior to the legalization of recreational cannabis. Health Promotion and Chronic Disease Prevention in Canada, 40(5/6), 193–200. https://doi.org/10.24095/hpcdp.40.5/6.08
  • Claudet, I., Mouvier, S., Labadie, M., Manin, C., Michard-Lenoir, A.-P., Eyer, D., Dufour, D., & Group, f. t. M.-J. S. (2017). Unintentional cannabis intoxication in toddlers. Pediatrics, 140(3).
  • Cooper, Z. D., & Haney, M. (2009). Comparison of subjective, pharmacokinetic, and physiological effects of marijuana smoked as joints and blunts. Drug and Alcohol Dependence, 103(3), 107–113.
  • Cooper, Z. D., & Haney, M. (2010). Opioid antagonism enhances marijuana’s effects in heavy marijuana smokers. Psychopharmacology, 211(2), 141–148.
  • Council of State & Territorial Epidemiologists Cannabis Subcommittee. (2021). Cannabis-related healthcare visits: Guidance for indicators using ICD-10-CM coded administrative data. https://cdn.ymaws.com/www.cste.org/resource/resmgr/crosscuttingi/Cannabis_ICD_Indicators_case.pdf
  • Desai, R., Fong, H. K., Shah, K., Kaur, V. P., Savani, S., Gangani, K., Damarlapally, N., & Goyal, H. (2019). Rising trends in hospitalizations for cardiovascular events among young cannabis users (18–39 Years) without other substance abuse. Medicina, 55(8), 438. https://doi.org/10.3390/medicina55080438
  • Desai, R., Patel, U., Sharma, S., Amin, P., Bhuva, R., Patel, M. S., Sharma, N., Shah, M., Patel, S., Savani, S., Batra, N., & Kumar, G. (2017). Recreational marijuana use and acute myocardial infarction: Insights from nationwide inpatient sample in the United States. Cureus, 9(11), e1816. https://doi.org/10.7759/cureus.1816
  • DeYoung, K., Chen, Y., Beum, R., Askenazi, M., Zimmerman, C., & Davidson, A. J. (2017). Validation of a syndromic case definition for detecting emergency department visits potentially related to marijuana. Public Health Reports (Washington, D.C.: 1974), 132(4), 471–479.
  • ElSohly, M. A., Mehmedic, Z., Foster, S., Gon, C., Chandra, S., & Church, J. C. (2016). Changes in cannabis potency over the last 2 decades (1995–2014): Analysis of current data in the United States. Biological Psychiatry, 79(7), 613–619. https://doi.org/10.1016/j.biopsych.2016.01.004
  • Fergusson, D. M., & Horwood, L. J. (2000). Does cannabis use encourage other forms of illicit drug use? Addiction (Abingdon, England), 95(4), 505–520.
  • Ford, B. M., Tai, S., Fantegrossi, W. E., & Prather, P. L. (2017). Synthetic pot: Not your grandfather’s Marijuana. Trends in Pharmacological Sciences, 38(3), 257–276.
  • Foundation for a Healthy Kentucky. (2017). Kentucky health issues poll, heroin, methamphetamine use and prescription drug abuse in Kentucky.
  • Freeman, T. P., Craft, S., Wilson, J., Stylianou, S., ElSohly, M., Di Forti, M., & Lynskey, M. T. (2021). Changes in delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD) concentrations in cannabis over time: Systematic review and meta-analysis. Addiction (Abingdon, England), 116(5), 1000–1010. https://doi.org/10.1111/add.15253
  • Goyal, H., Awad, H. H., & Ghali, J. K. (2017). Role of cannabis in cardiovascular disorders. Journal of Thoracic Disease, 9(7), 2079–2092.
  • Hall, K. E., Monte, A. A., Chang, T., Fox, J., Brevik, C., Vigil, D. I., Van Dyke, M., & James, K. A. (2018). Mental health-related emergency department visits associated with cannabis in Colorado. Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine, 25(5), 526–537.
  • Haney, M., Malcolm, R. J., Babalonis, S., Nuzzo, P. A., Cooper, Z. D., Bedi, G., Gray, K. M., McRae-Clark, A., Lofwall, M. R., Sparenborg, S., & Walsh, S. L. (2016). Oral cannabidiol does not alter the subjective, reinforcing or cardiovascular effects of smoked cannabis. Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology, 41(8), 1974–1982. https://doi.org/10.1038/npp.2015.367
  • Hart, C. L., Ward, A. S., Haney, M., Comer, S. D., Foltin, R. W., & Fischman, M. W. (2002). Comparison of smoked marijuana and oral Delta(9)-tetrahydrocannabinol in humans. Psychopharmacology, 164(4), 407–415.
  • Havens, J. R., Knudsen, H. K., Strickland, J. C., Young, A. M., Babalonis, S., Lofwall, M. R., & Walsh, S. L. (2022). Recent increase in methamphetamine use in a cohort of rural people who use drugs: Further evidence for the emergence of twin epidemics [Original Research]. Frontiers in Psychiatry, 12(805002).
  • Ingram, D. D., & Franco, S. J. (2014). NCHS urban–rural classification scheme for counties.
  • Jacobus, J., Courtney, K. E., Hodgdon, E. A., & Baca, R. (2019). Cannabis and the developing brain: What does the evidence say? Birth Defects Research, 111(17), 1302–1307.
  • Johnson-Sasso, C. P., Tompkins, C., Kao, D. P., & Walker, L. A. (2018). Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction. PloS One, 13(7), e0199705. https://doi.org/10.1371/journal.pone.0199705
  • Kane, K. (2021). Why are democrats blowing it on marijuana? Retrieved 2/2/2022, from https://www.forbes.com/sites/kriskrane/2021/12/23/why-are-democrats-blowing-it-on-marijuana/?sh=2a8926a71f60
  • Kentucky Office of Drug Control Policy. Kentucky’s drug epidemic. https://odcp.ky.gov/Resources/Pages/The-Heroin-Fentanyl-Epidemic.aspx
  • Keyes, K. M., Wall, M., Cerdá, M., Schulenberg, J., O’Malley, P. M., Galea, S., Feng, T., & Hasin, D. S. (2016). How does state marijuana policy affect US youth? Medical marijuana laws, marijuana use and perceived harmfulness: 1991–2014. Addiction (Abingdon, England), 111(12), 2187–2195. https://doi.org/10.1111/add.13523
  • Kim, P. C., Yoo, J. W., Cochran, C. R., Park, S.-M., Chun, S., Lee, Y.-J., & Shen, J. J. (2019). Trends and associated factors of use of opioid, heroin, and cannabis among patients for emergency department visits in Nevada: 2009–2017. Medicine, 98(47), e17739–e17739.
  • Klein, R. J., & Schoenborn, C. A. (2001). Age adjustment using the 2000 projected U.S. population. Healthy People 2010 Statistical Notes, 20, 1–10.
  • Lessem, J. M., Hopfer, C. J., Haberstick, B. C., Timberlake, D., Ehringer, M. A., Smolen, A., & Hewitt, J. K. (2006). Relationship between adolescent marijuana use and young adult illicit drug use. Behavior Genetics, 36(4), 498–506. https://doi.org/10.1007/s10519-006-9064-9
  • Lile, J. A., Kelly, T. H., & Hays, L. R. (2010). Substitution profile of the cannabinoid agonist nabilone in human subjects discriminating δ9-tetrahydrocannabinol. Clinical Neuropharmacology, 33(5), 235–242.
  • Manolis, T. A., Manolis, A. A., & Manolis, A. S. (2019). Cannabis associated "High" cardiovascular morbidity and mortality: Marijuana smoke like tobacco smoke? A Déjà Vu/Déjà Vécu story? Mini-Reviews in Medicinal Chemistry, 19(11), 870–879. https://doi.org/10.2174/1389557518666181114113947
  • Marx, G. E., Chen, Y., Askenazi, M., & Albanese, B. A. (2019). Syndromic surveillance of emergency department visits for acute adverse effects of marijuana, tri-county health department, Colorado, 2016–2017. Public Health Reports (Washington, D.C.: 1974), 134(2), 132–140. https://doi.org/10.1177/0033354919826562
  • Mehmedic, Z., Chandra, S., Slade, D., Denham, H., Foster, S., Patel, A. S., Ross, S. A., Khan, I. A., & ElSohly, M. A. (2010). Potency trends of Δ9-THC and other cannabinoids in confiscated cannabis preparations from 1993 to 2008. Journal of Forensic Sciences, 55(5), 1209–1217. https://doi.org/10.1111/j.1556-4029.2010.01441.x
  • Mittleman, M. A., Lewis, R. A., Maclure, M., Sherwood, J. B., & Muller, J. E. (2001). Triggering myocardial infarction by marijuana. Circulation, 103(23), 2805–2809.
  • Moreno-Mansilla, S., Ricarte, J. J., & Hallford, D. J. (2021). Cannabis use among early adolescents and transdiagnostic mental health risk factors. Clinical Child Psychology and Psychiatry, 26(2), 531–543.
  • Mustonen, A., Niemelä, S., Nordström, T., Murray, G. K., Mäki, P., Jääskeläinen, E., & Miettunen, J. (2018). Adolescent cannabis use, baseline prodromal symptoms and the risk of psychosis. The British Journal of Psychiatry, 212(4), 227–233. https://doi.org/10.1192/bjp.2017.52
  • National Conference of State Legislatures. (2022). State medical cannabis laws. https://www.ncsl.org/research/health/state-medical-marijuana-laws.aspx
  • National Institute on Drug Abuse. (2020a). Kentucky: Opioid-Involved Deaths and Related Harms. https://nida.nih.gov/drug-topics/opioids/opioid-summaries-by-state/kentucky-opioid-involved-deaths-related-harms
  • National Institute on Drug Abuse. (2020b). Trends & Statistics, Opioid Summaries by State. https://nida.nih.gov/drug-topics/opioids/opioid-summaries-by-state
  • O’Keefe, E. L., Peterson, T. M., & Lavie, C. J. (2021). Reevaluating America’s latest pharmaceutical trend: The cardiovascular risk of cannabis. Current Opinion in Psychology, 38, 31–37.
  • Pacek, L. R., Mauro, P. M., & Martins, S. S. (2015). Perceived risk of regular cannabis use in the United States from 2002 to 2012: Differences by sex, age, and race/ethnicity. Drug and Alcohol Dependence, 149, 232–244. https://doi.org/10.1016/j.drugalcdep.2015.02.009
  • Page, R. L., Allen, L. A., Kloner, R. A., Carriker, C. R., Martel, C., Morris, A. A., Piano, M. R., Rana, J. S., & Saucedo, J. F. (2020). Medical marijuana, recreational cannabis, and cardiovascular health: A scientific statement from the American Heart Association. Circulation, 142(10), e131–e152. https://doi.org/10.1161/CIR.0000000000000883
  • Pardo, M., Matalí, J. L., Sivoli, J., Regina, V. B., Butjosa, A., Dolz, M., Sánchez, B., Barajas, A., Del Cacho, N., Baños, I., Ochoa, S., & Usall, J. (2021). Early onset psychosis and cannabis use: Prevalence, clinical presentation and influence of daily use. Asian Journal of Psychiatry, 62, 102714.
  • Pratt, M., Stevens, A., Thuku, M., Butler, C., Skidmore, B., Wieland, L. S., Clemons, M., Kanji, S., & Hutton, B. (2019). Benefits and harms of medical cannabis: A scoping review of systematic reviews. Systematic Reviews, 8(1), 320.
  • Quan, H., Sundararajan, V., Halfon, P., Fong, A., Burnand, B., Luthi, J. C., Saunders, L. D., Beck, C. A., Feasby, T. E., & Ghali, W. A. (2005). Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Medical Care, 43(11), 1130–1139.
  • Richards, J. R., Smith, N. E., & Moulin, A. K. (2017). Unintentional cannabis ingestion in children: A systematic review. The Journal of Pediatrics, 190, 142–152.
  • Roberts, B. A. (2019). Legalized cannabis in Colorado emergency departments: A cautionary review of negative health and safety effects. The Western Journal of Emergency Medicine, 20(4), 557–572. https://doi.org/10.5811/westjem.2019.4.39935
  • Roberts, C. (2021). Top senate democrats: We’ll Legalize Marijuana. Forbes. https://www.forbes.com/sites/chrisroberts/2021/02/01/top-senate-democrats-well-legalize-marijuana/?sh=775e81a4215e
  • Salas-Wright, C. P., Carbone, J. T., Holzer, K. J., & Vaughn, M. G. (2019). Prevalence and correlates of cannabis poisoning diagnosis in a national emergency department sample. Drug and Alcohol Dependence, 204, 107564.
  • Schmid, Y., Scholz, I., Mueller, L., Exadaktylos, A. K., Ceschi, A., Liechti, M. E., & Liakoni, E. (2020). Emergency department presentations related to acute toxicity following recreational use of cannabis products in Switzerland. Drug and Alcohol Dependence, 206, 107726.
  • Shen, J. J., Shan, G., Kim, P. C., Yoo, J. W., Dodge-Francis, C., & Lee, Y. J. (2019). Trends and related factors of cannabis-associated emergency department visits in the United States: 2006–2014. Journal of Addiction Medicine, 13(3), 193–200. https://doi.org/10.1097/ADM.0000000000000479
  • Smart, R., Caulkins, J. P., Kilmer, B., Davenport, S., & Midgette, G. (2017). Variation in cannabis potency and prices in a newly legal market: Evidence from 30 million cannabis sales in Washington State. Addiction, 112(12), 2167–2177. https://doi.org/10.1111/add.13886
  • Spadari, M., Glaizal, M., Tichadou, L., Blanc, I., Drouet, G., Aymard, I., De Haro, L., Hayek-Lanthois, M., & Arditti, J. (2009). Accidental cannabis poisoning in children: Experience of the Marseille poison center. Presse Medicale (Paris, France: 1983), 38(11), 1563–1567.
  • Stogner, J. M., & Miller, B. L. (2015). Assessing the dangers of “Dabbing”: Mere Marijuana or Harmful New Trend? Pediatric, 2015, 136(1), 1–3.
  • Stoops, W. W., Tindall, M. S., Havens, J. R., Oser, C. B., Webster, J. M., Mateyoke-Scrivner, A., Wright, P. B., Booth, B. M., & Leukefeld, C. G. (2007). Kentucky rural stimulant use: A comparison of methamphetamine and other stimulant users. Journal of Psychoactive Drugs, 4, 407–417.
  • Substance Abuse & Mental Health Services Administration. (2021). 2020 National Survey of Drug Use and Health (NSDUH). https://www.samhsa.gov/data/release/2020-national-survey-drug-use-and-health-nsduh-releases
  • Tzilos, G. K., Reddy, M. K., Caviness, C. M., Anderson, B. J., & Stein, M. D. (2014). Getting higher: Co-occurring drug use among marijuana-using emerging adults. Journal of Addictive Diseases, 33(3), 202–209.
  • U.S. Census, Quick Facts, Kentucky. (2021). https://www.census.gov/quickfacts/fact/table/fayettecountykentucky,jeffersoncountykentucky,KY/PST045221
  • Victor, G. A., Walker, R., Cole, J., & Logan, T. K. (2017). Opioid analgesics and heroin: Examining drug misuse trends among a sample of drug treatment clients in Kentucky. The International Journal on Drug Policy, 46, 1–6.
  • Vivolo-Kantor, A., Pasalic, E., Liu, S., Martinez, P. D., & Gladden, R. M. (2021). Defining indicators for drug overdose emergency department visits and hospitalisations in ICD-10-CM coded discharge data. Injury Prevention, 27, i56.
  • Volkow, N. D., Baler, R. D., Compton, W. M., & Weiss, S. R. (2014). Adverse health effects of marijuana use. The New England Journal of Medicine, 370(23), 2219–2227.
  • Walsan, R., Mayne, D. J., Pai, N., Feng, X., & Bonney, A. (2019). Exploring the geography of serious mental illness and type 2 diabetes comorbidity in Illawarra-Shoalhaven, Australia (2010 -2017). PloS One, 14(12), e0225992. https://doi.org/10.1371/journal.pone.0225992
  • Wang, G. S. (2022). Cannabis (marijuana): Acute intoxication. UpToDate. https://www.uptodate.com/contents/cannabis-marijuana-acute-intoxication#disclaimerContent
  • Wang, G. S., Roosevelt, G., Le Lait, M. C., Martinez, E. M., Bucher-Bartelson, B., Bronstein, A. C., & Heard, K. (2014). Association of unintentional pediatric exposures with decriminalization of marijuana in the United States. Annals of Emergency Medicine, 63(6), 684–689.
  • Wood, D. M., De La Rue, L., Hosin, A. A., Jurgens, G., Liakoni, E., Heyerdahl, F., Hovda, K. E., Dines, A., Giraudon, I., Liechti, M. E., & Dargan, P. I. (2019). Poor identification of emergency department acute recreational drug toxicity presentations using routine hospital coding systems: The experience in Denmark, Switzerland and the UK. Journal of Medical Toxicology, 15(2), 112–120. https://doi.org/10.1007/s13181-018-0687-z
  • Zelner, I., Matlow, J., Hutson, J. R., Wax, P., Koren, G., Brent, J., & Finkelstein, Y. (2015). Acute poisoning during pregnancy: Observations from the toxicology investigators consortium. Journal of Medical Toxicology: Official Journal of the American College of Medical Toxicology, 11(3), 301–308. https://doi.org/10.1007/s13181-015-0467-y
  • Zhu, H., & Wu, L. T. (2016). Trends and correlates of cannabis-involved emergency department visits: 2004 to 2011. Journal of Addiction Medicine, 10(6), 429–436. https://doi.org/10.1097/ADM.0000000000000256

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