572
Views
31
CrossRef citations to date
0
Altmetric
Research Article

Mucoadhesive buccal film containing ornidazole and dexamethasone for oral ulcers: in vitro and in vivo studies

, , , , , & show all
Pages 118-126 | Received 05 Jun 2017, Accepted 10 Jan 2018, Published online: 25 Jan 2018

References

  • Akintoye SO, Greenberg MS. 2014. Recurrent aphthous stomatitis. Dent Clin North Am. 58:281–297.
  • Altenburg A, El-Haj N, Micheli C, Puttkammer M, Abdel-Naser MB, Zouboulis CC. 2014. The treatment of chronic recurrent oral aphthous ulcers. Dtsch Arztebl Int. 111:665–673.
  • Belenguer-Guallar I, Jimenez-Soriano Y, Claramunt-Lozano A. 2014. Treatment of recurrent aphthous stomatitis. A literature review. J Clin Exp Dent. 6:e168–e174.
  • Caon T, Simoes CM. 2011. Effect of freezing and type of mucosa on ex vivo drug permeability parameters. AAPS Pharmscitech. 12:587–592.
  • Cui RZ, Bruce AJ, Rogers RR. 2016. Recurrent aphthous stomatitis. Clin Dermatol. 34:475–481.
  • Devlieghere F, Vermeulen A, Debevere J. 2004. Chitosan: antimicrobial activity, interactions with food components and applicability as a coating on fruit and vegetables. Food Microbiol. 21:703–714.
  • Diaz-Del CI, Jacques Y, Pizzolato GP, Guy RH, Falson F. 2005. Comparison of the lipid composition of porcine buccal and esophageal permeability barriers. Arch Oral Biol. 50:981–987.
  • Du LD, Ni JM, Meng QG, Shi YB. 2007. Preparation of actinomycin D vaginal bioadhesive tablet. Chin J New Drugs. 5:387–390.
  • El SA, Shukr MH, Elshafeey AH. 2017. Formulation and optimization of duloxetine hydrochloride buccal films: in vitro and in vivo evaluation. Drug Deliv. 24:1762–1769.
  • Farshi FS, Ozer AY, Ercan MT, Hincal AA. 1996. In-vivo studies in the treatment of oral ulcers with liposomal dexamethasone sodium phosphate. J. Microencapsul. 13:537–544.
  • Ghalayani P, Emami H, Pakravan F, Nasr Isfahani M. 2017. Comparison of triamcinolone acetonide mucoadhesive film with licorice mucoadhesive film on radiotherapy-induced oral mucositis: a randomized double-blinded clinical trial. Asia-Pac J Clin Oncol. 13:e48–e56.
  • Gomes CC, Gomez RS, Zina LG, Amaral FR. 2016. Recurrent aphthous stomatitis and Helicobacter pylori. Med Oral Patol Oral Cir Bucal. 21:e187–e191.
  • Holbrook WP, Kristmundsdottir T, Loftsson T. 1998. Aqueous hydrocortisone mouthwash solution: clinical evaluation. Acta Odontol Scand. 56:157–160.
  • Juliano C, Cossu M, Pigozzi P, Rassu G, Giunchedi P. 2008. Preparation, in vitro characterization and preliminary in vivo evaluation of buccal polymeric films containing chlorhexidine. AAPS Pharmscitech. 9:1153–1158.
  • Karavana HS, Sezer B, Guneri P, Veral A, Boyacioglu H, Ertan G, Epstein JB. 2011. Efficacy of topical benzydamine hydrochloride gel on oral mucosal ulcers: an in vivo animal study. Int J Oral Maxillofac Surg. 40:973–978.
  • Kumria R, Nair AB, Al-Dhubiab BE. 2014. Loratidine buccal films for allergic rhinitis: development and evaluation. Drug Dev Ind Pharm. 40:625–631.
  • Laffleur F. 2014. Mucoadhesive polymers for buccal drug delivery. Drug Dev Ind Pharm. 40:591–598.
  • Laffleur F, Ataii M. 2017. Preparation and evaluation of a novel dosage form for onychomycosis. Int J Pharm. 518:105–110.
  • Liew KB, Odeniyi MA, Peh KK. 2016. Application of freeze-drying technology in manufacturing orally disintegrating films. Pharm Dev Technol. 21:346–353.
  • Lim YS, Kwon SK, Park JH, Cho CG, Park SW, Kim WK. 2016. Enhanced mucosal healing with curcumin in animal oral ulcer model. Laryngoscope. 126:E68–E73.
  • Liu C, Zhou Z, Liu G, Wang Q, Chen J, Wang L, Zhou Y, Dong G, Xu X, Wang Y, et al. 2012. Efficacy and safety of dexamethasone ointment on recurrent aphthous ulceration. Am J Med. 125:292–301.
  • Lodhi M, Dubey A, Narayan R, Prabhu P, Priya S. 2013. Formulation and evaluation of buccal film of Ivabradine hydrochloride for the treatment of stable angina pectoris. Int J Pharma Investig. 3:47–53.
  • Maderuelo C, Zarzuelo A, Lanao JM. 2011. Critical factors in the release of drugs from sustained release hydrophilic matrices. J Control Release. 154:2–19.
  • Meher JG, Tarai M, Yadav NP, Patnaik A, Mishra P, Yadav KS. 2013. Development and characterization of cellulose-polymethacrylate mucoadhesive film for buccal delivery of carvedilol. Carbohydr Polym. 96:172–180.
  • Morales JO, McConville JT. 2011. Manufacture and characterization of mucoadhesive buccal films. Eur J Pharm Biopharm. 77:187–199.
  • Mukherjee D, Bharath S. 2013. Design and characterization of double layered mucoadhesive system containing bisphosphonate derivative. ISRN Pharm 2013. 2013:1.
  • Mura P, Corti G, Cirri M, Maestrelli F, Mennini N, Bragagni M. 2010. Development of mucoadhesive films for buccal administration of flufenamic acid: effect of cyclodextrin complexation. J Pharm Sci. 99:3019–3029.
  • Ng SF, Tan SL. 2015. Development and in vitro assessment of alginate bilayer films containing the olive compound hydroxytyrosol as an alternative for topical chemotherapy. Int J Pharm. 495:798–806.
  • Nguyen S, Hiorth M. 2015. Advanced drug delivery systems for local treatment of the oral cavity. Ther Deliv. 6:595–608.
  • Park DM, Song YK, Jee JP, Kim HT, Kim CK. 2012. Development of chitosan-based ondansetron buccal delivery system for the treatment of emesis. Drug Dev Ind Pharm. 38:1077–1083.
  • Perioli L, Ambrogi V, Angelici F, Ricci M, Giovagnoli S, Capuccella M, Rossi C. 2004. Development of mucoadhesive patches for buccal administration of ibuprofen. J Control Release. 99:73–82.
  • Pradeep AR, Kalra N, Priyanka N, Naik SB. 2012. Microbiological outcomes of systemic ornidazole use in chronic periodontitis. Part II. J Int Acad Periodontol. 14:50–54.
  • Rajesh P, Gunasekaran S, Gnanasambandan T, Seshadri S. 2016. Experimental and theoretical study of ornidazole. Spectrochim Acta A Mol Biomol Spectrosc. 153:496–504.
  • Salamat-Miller N, Chittchang M, Johnston TP. 2005. The use of mucoadhesive polymers in buccal drug delivery. Adv Drug Deliv Rev. 57:1666–1691.
  • Samtani MN, Jusko WJ. 2005. Stability of dexamethasone sodium phosphate in rat plasma. Int J Pharm. 301:262–266.
  • Singarayar S, Kistler PM, De Winter C, Mond H. 2005. A comparative study of the action of dexamethasone sodium phosphate and dexamethasone acetate in steroid-eluting pacemaker leads. Pacing Clin Electrophysiol. 28:311–315.
  • Singh S, Soni R, Rawat MK, Jain A, Deshpande SB, Singh SK, Muthu MS. 2010. In vitro and in vivo evaluation of buccal bioadhesive films containing salbutamol sulphate. Chem Pharm Bull. 58:307–311.
  • Smart JD. 2005. The basics and underlying mechanisms of mucoadhesion. Adv Drug Deliv Rev. 57:1556–1568.
  • Usman A, Zia KM, Zuber M, Tabasum S, Rehman S, Zia F. 2016. Chitin and chitosan based polyurethanes: a review of recent advances and prospective biomedical applications. Int J Biol Macromol. 86:630–645.
  • Vasantha PV, Puratchikody A, Mathew ST, Balaraman AK. 2011. Development and characterization of Eudragit based mucoadhesive buccal patches of salbutamol sulfate. Saudi Pharm J. 19:207–214.
  • Wang LC, Chen XG, Liu CS, Li LD, Ji QX, Yu LJ. 2008. Preparation of a multistructural film with CM-chitosan and PVA, and in vitro ornidazole release from the carrier. J Appl Polym Sci. 110:1136–1144.
  • Wang Y, Zhang P, Jiang N, Gong X, Meng L, Wang D, Ou N, Zhang H. 2012. Simultaneous quantification of metronidazole, tinidazole, ornidazole and morinidazole in human saliva. J Chromatogr B Analyt Technol Biomed Life Sci. 899:27–30.
  • Xiong LQ, Li GF, Su BY, Liu Y, Wang L. 2011. A study on the relationship between the oil/water partition coefficient and transdermal action of drugs: dexamethasone acetate and dexamethansone sodium phosphate. Chin Pharm J. 6:439–446.
  • Yedurkar P, Dhiman MK, Petkar K, Sawant K. 2013. Biopolymeric mucoadhesive bilayer patch of pravastatin sodium for buccal delivery and treatment of patients with atherosclerosis. Drug Dev Ind Pharm. 39:670–680.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.