A novel technique to evaluate nail softening effects of different urea formulations

References

• Baran R, Coquard F. 2005. Combination of fluconazole and urea in a nail lacquer for treating onychomycosis. J Dermatolog Treat. 16(1):52–55.
   PubMed Web of Science ®Google Scholar
• Chiacchio ND, Kadunc BV, Almeida ARTD, Madeira CL. 2003. Nail abrasion. J Cosmet Dermatol. 2(3-4):150–152.
   PubMedGoogle Scholar
• Chouhan P, Saini TR. 2012. Hydration of nail plate: a novel screening model for transungual drug permeation enhancers. Int J Pharm. 436(1-2):179–182.
   PubMedGoogle Scholar
• Egawa M, Ozaki Y, Takahashi M. 2006. In vivo measurement of water content of the fingernail and its seasonal change. Skin Res Technol. 12(2):126–132.
   PubMed Web of Science ®Google Scholar
• Finlay AY, Western B, Edwards C. 1990. Ultrasound velocity in human fingernail and effects of hydration: validation of in vivo nail thickness measurement techniques. Br J Dermatol. 123(3):365–373.
   PubMed Web of Science ®Google Scholar
• Hao J, Smith KA, Li SK. 2010. Time-dependent electrical properties of human nail upon hydration in vivo. J Pharm Sci. 99(1):107–118.
   PubMed Web of Science ®Google Scholar
• Hui X, Wester RC, Barbadillo S, Lee C, Patel B, Wortzmman M, Gans EH, Maibach HI. 2004. Ciclopirox delivery into the human nail plate. J Pharm Sci. 93(10):2545–2548.
   PubMed Web of Science ®Google Scholar
• Jemec GBE, Agner T, Serup J. 1989. Transonychial water loss: relation to sex, age and nail-plate thickness. Br J Dermatol. 121(4):443–446.
   PubMed Web of Science ®Google Scholar
• Khengar RH, Jones SA, Turner RB, Forbes B, Brown MB. 2007. Nail swelling as a pre-formulation screen for the selection and optimisation of ungual penetration enhancers. Pharm Res. 24(12):2207–2212.
   PubMed Web of Science ®Google Scholar
• Kobayashi Y, Komatsu T, Sumi M, Numajiri S, Miyamoto M, Kobayashi D, Sugibayashi K, Morimoto Y. 2004. In vitro permeation of several drugs through the human nail plate: relationship between physicochemical properties and nail permeability of drugs. Eur J Pharm Sci. 21(4):471–477.
   PubMed Web of Science ®Google Scholar
• Lusiana Reichl S, Müller-Goymann CC. 2011. Keratin film made of human hair as a nail plate model for studying drug permeation. Eur J Pharm Biopharm. 78(3):432–440.
   PubMed Web of Science ®Google Scholar
• Malhotra GG, Zatz JL. 2002. Investigation of nail permeation enhancement by chemical modification using water as a probe. J Pharm Sci. 91(2):312–323.
   PubMed Web of Science ®Google Scholar
• Martinsen OG, Grimnes S, Nilsen SH. 2008. Water sorption and electrical properties of a human nail. Skin Res Technol. 14(2):142–146.
   PubMed Web of Science ®Google Scholar
• Mertin D, Lippold BC. 1997. In-vitro permeability of the human nail and of a keratin membrane from bovine hooves: penetration of chloramphenicol from lipophilic vehicles and a nail lacquer. J Pharm Pharmacol. 49(3):241–245.
   PubMed Web of Science ®Google Scholar
• Miron D, Cornelio R, Troleis J, Mariath J, Zimmer AR, Mayorga P, Schapoval EES. 2014. Influence of penetration enhancers and molecular weight in antifungals permeation through bovine hoof membranes and prediction of efficacy in human nails. Eur J Pharm Sci. 51:20–25.
   PubMed Web of Science ®Google Scholar
• Monti D, Saccomani L, Chetoni P, Burgalassi S, Saettone MF, Mailland F. 2005. In vitro transungual permeation of ciclopirox from a hydroxypropyl chitosan-based, water-soluble nail lacquer. Drug Dev Ind Pharm. 31(1):11–17.
   PubMed Web of Science ®Google Scholar
• Monti D, Saccomani L, Chetoni P, Burgalassi S, Tampucci S, Mailland F. 2011. Validation of bovine hoof slices as a model for infected human toenails: in vitro ciclopirox transungual permeation. Br J Dermatol. 165(1):99–105.
   PubMed Web of Science ®Google Scholar
• Murdan S. 2002. Drug delivery to the nail following topical application. Int J Pharm. 236(1-2):1–26.
   PubMed Web of Science ®Google Scholar
• Murdan S, Hinsu D, Guimier M. 2008. A few aspects of transonychial water loss (TOWL): Inter-individual, and intra-individual inter-finger, inter-hand and inter-day variabilities, and the influence of nail plate hydration, filing and varnish. Eur J Pharm Biopharm. 70(2):684–689.
   PubMed Web of Science ®Google Scholar
• Nguyen HX, Banga AK. 2018. Effect of ablative laser on in vitro transungual delivery. Int J Pharm. 544(2):402–414.
   PubMedGoogle Scholar
• Nguyen HX, Bozorg BD, Kim Y, Wieber A, Birk G, Lubda D, Banga AK. 2018. Poly (vinyl alcohol) microneedles: Fabrication, characterization, and application for transdermal drug delivery of doxorubicin. Eur J Pharm Biopharm. 129:88–103.
   PubMed Web of Science ®Google Scholar
• Nogueiras-Nieto L, Gómez-Amoza JL, Delgado-Charro MB, Otero-Espinar FJ. 2011. Hydration and N-acetyl-l-cysteine alter the microstructure of human nail and bovine hoof: Implications for drug delivery. J Control Release. 156(3):337–344.
   PubMed Web of Science ®Google Scholar
• Salter SA, Ciocon DH, Gowrishankar TR, Kimball AB. 2006. Controlled nail trephination for subungual hematoma. Am J Emerg Med. 24(7):875–877.
   PubMed Web of Science ®Google Scholar
• Saner MV, Kulkarni AD, Pardeshi CV. 2014. Insights into drug delivery across the nail plate barrier. J Drug Target. 22(9):769–789.
   PubMed Web of Science ®Google Scholar
• Sattler E, Kaestle R, Rothmund G, Welzel J. 2012. Confocal laser scanning microscopy, optical coherence tomography and transonychial water loss for in vivo investigation of nails. Br J Dermatol. 166(4):740–746.
   PubMed Web of Science ®Google Scholar
• Scherer WP, Scherer MD. 2004. Scanning electron microscope imaging of onychomycosis. J Am Podiatr Med Assoc. 94(4):356–362.
   PubMed Web of Science ®Google Scholar
• Täuber A, Müller-Goymann CC. 2015. In vitro permeation and penetration of ciclopirox olamine from poloxamer 407-based formulations-comparison of isolated human stratum corneum, bovine hoof plates and keratin films. Int J Pharm. 489(1-2):73–82.
   PubMedGoogle Scholar
• Vejnovic I, Simmler L, Betz G. 2010. Investigation of different formulations for drug delivery through the nail plate. Int J Pharm. 386(1-2):185–194.
   PubMedGoogle Scholar
• Vignardet C, Guillaume YC, Friedrich J, Millet J. 1999. A first order experimental design to assess soluble proteins released by a new keratinase from Doratomyces microsporus on human substrates. Int J Pharm. 191(2):95–102.
   PubMedGoogle Scholar
• Yue X, Li Q, Wang H, Sun Y, Wang A, Zhang Q, Zhang C. 2016. Scanning electron microscopy of the nail plate in onychomycosis patients with negative fungal culture. Scanning. 38(2):172–176.
   PubMed Web of Science ®Google Scholar