87
Views
4
CrossRef citations to date
0
Altmetric
Technical Note

Preparation and evaluation of fast-dissolving films of etilefrine hydrochloride for practical buccal dosing

&
Pages 610-616 | Received 25 Nov 2020, Accepted 13 Mar 2021, Published online: 31 Mar 2021

References

  • Abruzzo A, Nicoletta FP, Dalena F, Cerchiara T, Luppi B, Bigucci F. 2017. Bilayered buccal films as child-appropriate dosage form for systemic administration of propranolol. Int J Pharm. 531(1):257–265.
  • Adigun SA, Fentem PH. 1984. A comparison of the effects of salbutamol, etilefrine and dextran during hypotension and low cardiac output states in rabbit. Clin Exp Pharmacol Physiol. 11(6):627–643.
  • Boehringer-Ingelheim J. 2014. Effortil Injection 10 mg. Drug Interview Form. 5th ed.
  • Bouaggad A, Harrar RA, Bouderka MA, Abassi O. 2000. The effect of oral etilefrine premedication on the incidence of hypotension during spinal anaesthesia. Eur J Anaesthesiol. 17(3):177–181.
  • Campbell C, Morimoto BH, Nenciu D, Fox AW. 2012. Drug development of intranasally delivered peptides. Ther Deliv. 3(4):557–568.
  • Coleman AJ, Leary WP, Asmal AC. 1975. The cardiovascular effects of etilefrine. Eur J Clin Pharmacol. 8(1):41–45.
  • Del Pinto R, Ferri C. 2019. Hypertension management at older age: an update. High Blood Press Cardiovasc Prev. 26(1):27–36.
  • Diaz Del Consuelo I, Falson F, Guy RH, Jacques Y. 2005. Transport of fentanyl through pig buccal and esophageal epithelia in vitro: influence of concentration and vehicle pH. Pharm Res. 22(9):1525–1529.
  • Fransén N, Bredenberg S, Björk S. 2009. Clinical study shows improved absorption of desmopressin with novel formulation. Pharm Res. 26(7):1618–1625.
  • Haustein KO, Hüller G. 1985. Bioavailability of etilefrine from Thomasin and Thomasin sustained-release tablets. Pharmazie. 40(11):776–778.
  • Hengstmann JH, Weyand U, Dengler HJ. 1975. The physiological disposition of etilefrine in man. Eur J Clin Pharmacol. 9(2–3):179–187.
  • Karasawa Y, Furukawa Y, Murakami M, Ren LM, Takayama S, Chiba S. 1992. Pharmacological analysis of positive chronotropic and inotropic responses to etilefrine in isolated dog heart preparations. Heart Vessels. 7(1):24–30.
  • Khan S, Trivedi V, Boateng J. 2016. Functional physico-chemical, ex vivo permeation and cell viability characterization of omeprazole loaded buccal films for paediatric drug delivery. Int J Pharm. 500(1–2):217–226.
  • Kuritzky L, Espay AJ, Gelblum J, Payne R, Dietrich E. 2015. Diagnosing and treating neurogenic orthostatic hypotension in primary care. Postgrad Med. 127(7):702–715.
  • Low PA, Tomalia VA. 2015. Orthostatic hypotension: mechanisms, causes, management. J Clin Neurol. 11(3):220–226.
  • Luukinen H, Koski K, Laippala P, Kivelä SL. 1999. Prognosis of diastolic and systolic orthostatic hypotension in older persons. Arch Intern Med. 159(3):273–280.
  • Madhav NVS, Shakya AK, Shakya P, Singh K. 2009. Orotransmucosal drug delivery systems: a review. J Control Release. 140(1):2–11.
  • Matsubara K, Abe K, Irie T, Uekama K. 1995. Improvement of nasal bioavailability of luteinizing hormone-releasing hormone agonist, buserelin, by cyclodextrin derivatives in rats. J Pharm Sci. 84(11):1295–1300.
  • Mol A, Reijnierse EM, Bui Hoang PTS, van Wezel RJA, Meskers CGM, Maier AB. 2018. Orthostatic hypotension and physical functioning in older adults: a systematic review and meta-analysis. Ageing Res Rev. 48:122–144.
  • Morales JO, McConville JT. 2011. Manufacture and characterization of mucoadhesive buccal films. Eur J Pharm Biopharm. 77(2):187–199.
  • Nair AB, Kumria R, Harsha S, Attimarad M, Al-Dhubiab BE, Alhaider IA. 2013. In vitro techniques to evaluate buccal films. J Control Release. 166(1):10–21.
  • Ogiso T, Iwaki M, Tamaki E. 1984. Absorption and bioavailability of calcium and magnesium salts of indomethacin from rectal suppositories. J Pharmacobiodyn. 7(6):392–399.
  • Ohya Y, Ohtsubo T, Tsuchihashi T, Eto K, Sadanaga T, Nagao T, Abe I, Fujishima M. 2001. Altered diurnal variation of blood pressure in elderly subjects with decreased activity of daily living and impaired cognitive function. Hypertens Res. 24(6):655–661.
  • Onishi H, Sakata O. 2018. Absorption behavior of etilefrine after buccal administration in rats. Int J Pharm. 550(1–2):14–23.
  • Rossi S, Sandri G, Caramella CM. 2005. Buccal drug delivery: a challenge already won? Drug Discov Today Technol. 2(1):59–65.
  • Sakata O, Onishi H. 2020. Preparation of orally fast-dissolving tablets of etilefrine hydrochloride to achieve efficient absorption. Pharm Dev Technol. 25(9):1162–1167.
  • Sayani AP, Chien YW. 1996. Systemic delivery of peptides and proteins across absorptive mucosae. Crit Rev Ther Drug Carrier Syst. 13(1–2):85–184.
  • Siepmann J, Siepmann F. 2020. Sink conditions do not guarantee the absence of saturation effects. Int J Pharm. 577:119009.
  • Tocci G, Borghi C, Volpe M. 2014. Clinical management of patients with hypertension and high cardiovascular risk: main results of an Italian survey on. High Blood Press Cardiovasc Prev. 21(2):107–117.
  • Trastullo R, Abruzzo A, Saladini B, Gallucci MC, Cerchiara T, Luppi B, Bigucci F. 2016. Design and evaluation of buccal films as paediatric dosage form for transmucosal delivery of ondansetron. Eur J Pharm Biopharm. 105:115–121.
  • Yamaoka K, Tanigawara Y, Nakagawa T, Uno T. 1981. A pharmacokinetic analysis program (multi) for microcomputer. J Pharmacobiodyn. 4(11):879–885.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.