120
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

Formulation design, optimization and in vivo evaluation of oral co-encapsulated resveratrol-humic acid colloidal polymeric nanocarriers

, &
Pages 953-966 | Received 30 Jan 2021, Accepted 06 Aug 2021, Published online: 19 Aug 2021

References

  • Acharya SB, Frotan MH, Goel RK, Tripathi SK, Das PK. 1988. Pharmacological actions of Shilajit. Indian J Exp Biol. 26(10):775–787.
  • Agarwal SP, Anwer MDK, Khanna R, Ali A, Sultana Y. 2010. Humic acid from Shilajit-a physico-chemical and spectroscopic characterization. J Serb Chem Soc. 75(3):413–422.
  • Agarwal SP, Khanna R, Karmarkar R, Anwer MK, Khar RK. 2007. Shilajit: a review. Phytother Res. 21(5):401–405.
  • Amri A, Chaumeil JC, Sfar S, Charrueau C. 2012. Administration of resveratrol: what formulation solutions to bioavailability limitations? J Control Release. 158(2):182–193.
  • Anderson HA, Bick W, Hepburn A, Stewart M. 1989. Humic substances II. In: Hayes MHB, MacCarthy P, Malcolm RL, Swift RS, editors. Search of structure. Chichester (UK): Wiley-Interscience. p. 223.
  • Baur AJ, Sinclair DA. 2006. Therapeutic potential of resveratrol: the in vivo evidence. Nat Rev Drug Discov. 5(6):493–506.
  • Barzegar-Jalali M, Alaei-Beirami M, Javadzadeh Y, Mohammadi G, Hamidi A, Andalib S, Adibkia K. 2012. Comparison of physicochemical characteristics and drug release of diclofenac sodium-eudragit (R) RS100 nanoparticles and solid dispersions. Powder Technol. 219:211–216.
  • Buchanan CM, Buchanan NL, Edgar KJ, Little JL, Malcolm MO, Ruble KM, Wacher VJ, Wempe MF. 2007. Pharmacokinetics of tamoxifen after intravenous and oral dosing of tamoxifen-hydroxybutenyl-beta-cyclodextrin formulations. J Pharm Sci. 96(3):644–660.
  • Bhagav P, Upadhyay H, Chandran S. 2011. Brimonidine tartrate-eudragit long-acting nanoparticles: formulation, optimization, in vitro and in vivo evaluation. AAPS PharmSciTech. 12(4):1087–1101.
  • Chaurasia S, Chaubey P, Patel RR, Kumar N, Mishra B. 2016. Curcumin-polymeric nanoparticles against colon-26 tumor-bearing mice: cytotoxicity, pharmacokinetic and anticancer efficacy studies. Drug Dev Ind Pharm. 42(5):694–700.
  • Chaurasia S, Kumar N, Patel RR, Mishra B. 2014. Optimization of parameters for the fabrication of curcumin loaded polymeric nanoparticles using Taguchi robust design. Adv Sci Lett. 20(5):1028–1038.
  • Chaubey P, Patel RR, Mishra B. 2014. Development and optimization of curcumin-loaded mannosylated chitosan nanoparticles using response surface methodology in the treatment of visceral leishmaniasis. ExpOpin on Drug Deliv. 11(8):1163–1181.
  • Chakraborty S, Shukla D, Vuddanda PR, Mishra B, Singh S. 2010. Utilization of adsorption technique in the development of oral delivery system of lipid based nanoparticles. Colloids Surf B Biointerfaces. 81(2):563–569.
  • Chaurasia S, Patel RR, Chaubey P, Kumar N, Khan G, Mishra B. 2015. Lipopolysaccharide based oral nanocarriers for the improvement of bioavailability and anticancer efficacy of curcumin. Carbohydr Polym. 130:9–17.
  • Chilom G, Rice JA. 2005. Glass transition and crystallite melting in natural organic matter. Org Geochem. 36(10):1339–1346.
  • Chawla R, Jaiswal S, Mishra B. 2014. Development and optimization of polymeric nanoparticles of antitubercular drugs using central composite factorial design. Expert Opin Drug Deliv. 11(1):31–43.
  • Costa P, Sousa JM. 2001. Modeling and comparison of dissolution profiles. Eur J Pharm Sci. 13(2):123–133.
  • Danhier F, Lecouturier N, Vroman B, Jérôme C, Marchand-Brynaert J, Feron O, Préat V. 2009. Paclitaxel-loaded PEGylated PLGA-based nanoparticles: in vitro and in vivo evaluation. J Control Release. 133(1):11–17.
  • Dillen K, Vandervoort J, Mooter GV, Ludwig A. 2006. Evaluation of ciprofloxacin-loaded Eudragit RS100 or RL100/PLGA nanoparticles. Int J Pharm. 314(1):72–82.
  • Des Rieux A, Fievez V, Garinot M, Schneider YJ, Préat V. 2006. Nanoparticles as potential oral delivery systems of proteins and vaccines: a mechanistic approach. J Control Release. 116(1):1–27.
  • Emı́lia Juan M, Buenafuente J, Casals I, Planas JM. 2002. Plasmatic levels of trans-resveratrol in rats. Food Res Int. 35(2–3):195–199.
  • Elshafeey AH, Kamel AO, Awad GA. 2010. Ammonium methacrylate units polymer content and their effect on acyclovir colloidal nanoparticles properties and bioavailability in human volunteers. Colloids Surf B Biointerfaces. 75(2):398–404.
  • Fremont L. 2000. Biological effects of resveratrol. Life Sci. 66(8):663–673.
  • Fessi H, Puisieux F, Devissaguet JP, Ammoury N, Benita S. 1989. Nanocapsule formation by interfacial polymer deposition following solvent displacement. Int J Pharm. 55(1):R1–R4.
  • Gupta S, Dube A, Vyas SP. 2012. Development and characterization of amphotericin B loaded solid lipid nanoparticles against experimental visceral leishmaniasis. PNT. 1(1):54–67.
  • Gupta S, Gupta MK. 2017. Possible role of nanocarriers in drug delivery against cervical cancer. Nano Rev Exp. 8(1):1335567.
  • Gupta S, Kumar P. 2012. Drug delivery using nanocarriers: Indian perspective. Proc Natl Acad Sci India Sect B Biol Sci. 82(S1):167–206.
  • Gupta S, Kumar P, Gupta MK, Vyas SP. 2012. Colloidal carriers: a rising tool for therapy of tuberculosis. Crit Rev Ther Drug Carrier Syst. 29(4):299–353.
  • Ghosal S. 2003. Delivery system for pharmaceutical, nutritional and cosmetic ingredients. US patent no. 6558712.
  • Intagliata S, Modica MN, Santagati LM, Montenegro L. 2019. Strategies to improve resveratrol systemic and topical bioavailability: An update. Antioxidants. 8(8):244.
  • Jiang Z, Chen K, Cheng L, Yan B, Qian W, Cao J, Li J, Wu E, Ma Q, Yang W. 2017. Resveratrol and cancer treatment: updates. Ann N Y Acad Sci. 1403(1):59–69.
  • Jahanshahi M, Najafpour G, Rahimnejad M. 2008. Applying the Taguchi method for optimized fabrication of bovine serum albumin (BSA) nanoparticles as drug delivery vehicles. Afr J Biotechnol. 7(4):362–367.
  • Kong YC, But PPH, Ng KH, Cheng KF, Cambie RC, Malla SB. 1987. Chemical studies on a Napalese panacea; Shilajit. Int J Crude Drug Res. 25(3):179–187.
  • Kristl J, Teskac K, Caddeo C, Abramović Z, Sentjurc M. 2009. Improvements of cellular stress response on Resveratrol in liposomes. Eur J Pharm Biopharm. 73(2):253–259.
  • Kang OH, Jang HJ, Chae HS, Oh YC, Choi JG, Lee YS, Kim JH, Kim YC, Sohn DH, Park H, Kwon DY. 2009. Anti-inflammatory mechanisms of resveratrol in activated HMC-1 cells: pivotal roles of NF-kappaB and MAPK . Pharmacol Res. 59(5):330–337.
  • Kumar N, Chaurasia S, Patel RR, Khan G, Kumar V, Mishra B. 2017. Atorvastatin calcium encapsulated eudragit nanoparticles with enhanced oral bioavailability, safety and efficacy profile. Pharm Dev Technol. 22(2):156–167.
  • Kurin E, Mučaji P, Nagy M. 2012. In vitro antioxidant activities of three red wine polyphenols and their mixtures: an interaction study. Molecules. 17(12):14336–14348.
  • Kim S, Ng WK, Dong Y, Das S, Tan RBH. 2012. Preparation and physicochemical characterization of trans-resveratrol nanoparticles by temperature-controlled antisolvent precipitation. J Food Eng. 108(1):37–42.
  • Kumar N, Chaurasia S, Patel RR, Kumar V, Mishra B. 2014. Development and optimization of atorvastatin calcium loaded oral biodegradable polymeric nanoparticles using central composite design. Adv Sci Lett. 20(5):984–993.
  • Kim J-H, Park E-Y, Ha H-K, Jo C-M, Lee W-J, Lee SS, Kim JW. 2016. Resveratrol-loaded nanoparticles induce antioxidant activity against oxidative stress. Asian-Australas J Anim Sci. 29(2):288–298.
  • Lu Z, Cheng B, Hu YL, Zhang YH, Zou GL. 2009. Complexation of resveratrol with cyclodextrins: solubility and antioxidant activity. Food Chem. 113(1):17–20.
  • Lopedota A, Trapani A, Cutrignelli A, Chiarantini L, Pantucci E, Curci R, Manuali E, Trapani G. 2009. The use of Eudragit RS 100/cyclodextrin nanoparticles for the transmucosal administration of glutathione. Eur J Pharm Biopharm. 72(3):509–520.
  • Lu X, Ji C, Xu H, Li X, Ding H, Ye M, Zhu Z, Ding D, Jiang X, Ding X, et al. 2009. Resveratrol-loaded polymeric micelles protect cells from Abeta-induced oxidative stress. Int J Pharm. 375(1-2):89–96.
  • Mainardes RM, Evangelista RC. 2005. PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution. Int J Pharm. 290(1-2):137–144.
  • Mirza MA, Agarwal SP, Rahman MA, Rauf A, Ahmad N, Alam A, Iqbal Z. 2011. Role of humic acid on oral drug delivery of an antiepileptic drug. Drug Dev Ind Pharm. 37(3):310–319.
  • Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM. 1995. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta. 235(2):207–219.
  • Patel RR, Khan G, Chaurasia S, Kumar N, Mishra B. 2015. Rationally developed core-shell polymeric-lipid hybrid nanoparticles as a delivery vehicle for cromolyn sodium: implications of lipid envelop on in vitro and in vivo behaviour of nanoparticles upon oral administration. RSC Adv. 5(93):76491–76506.
  • Pietro M, Paola C. 2004. Thermal analysis for the evaluation of the organic matter evolution during municipal solid waste aerobic composting process. Thermochim Acta. 413(1–2):209–214.
  • Quintanar D, Allémann E, Fessi H, Doelker E. 1998. Preparation techniques and mechanisms of formation of biodegradable nanoparticles from preformed polymers. Drug Dev Ind Pharm. 24(12):1113–1128.
  • Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, Rice-Evans C. 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radic Biol Med. 26(9–10):1231–1237.
  • Sharma U, Badyal PN, Gupta S. 2015. Polymeric nanoparticles drug delivery to brain: a review. Int J Pharmacol Pharmaceut Sci. 2(5):60–69.
  • Sharma S, Kumar P, Jaiswal A, Dube A, Gupta S. 2011. Development and characterization of doxorubicin loaded microparticles against experimental visceral leishmaniasis. J Biomed Nanotechnol. 7(1):135–136.
  • Signorelli P, Ghidoni R. 2005. Resveratrol as an anticancer nutrient: molecular basis, open questions and promises. J Nutr Biochem. 16(8):449–466.
  • Shah VP, Amidon GL. 2014. GL Amidon, H. Lennernas, VP Shah, and JR Crison. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability, Pharm Res 12, 413-420, 1995-backstory of BCS . Aaps J. 16(5):894–898.
  • Singh G, Pai RS, Pandit V. 2012. Development and validation of a HPLC method for the determination of trans-resveratrol in spiked human plasma. J Adv Pharm Technol Res. 3(2):130–135.
  • Santos KCD, Silva MF, Pereira-Filho ER, Fernandes JB, Polikarpov I, Forim MR. 2012. Polymeric nanoparticles loaded with the 3,5,3'-triiodothyroacetic acid (Triac), a thyroid hormone: factorial design, characterization, and release kinetics. Nanotechnol Sci Appl. 5:37–48.
  • Singh S, Muthu MS. 2008. Studies on biodegradable polymeric nanoparticles of risperidone: in vitro and in vivo evaluation. Nanomedicine (Lond). 3(3):305–319.
  • Seremeta KP, Reyes Tur MI, PéRez SM, Hocht C, Taira C, HernáNdez ODL, Sosnik A. 2014. Spray-dried didanosine-loaded polymeric particles for enhanced oral bioavailability. Colloids Surf B Biointerface. 123:515–523.
  • Tariq M, Alam MA, Singh AT, Iqbal Z, Panda AK, Talegaonkar S. 2015. Biodegradable polymeric nanoparticles for oral delivery of epirubicin: in vitro, ex vivo, and in vivo investigations. Colloids Surf B Biointerface. 128:448–456.
  • Tabata Y, Ikada Y. 1990. Phagocytosis of polymer microspheres by macrophages. Adv Polym Sci. 94:107–141.
  • Vella R, Bowen C, Fenning A. 2008. Prevention of cardiovascular damage in hypertensive rats by resveratrol. Heart Lung Circ. 17S:S219–S41.
  • Visser SA, Mendel H. 1971. X-ray diffraction studies on the crystallinity and molecular weight of humic acids. Soil Biol Biochem. 3(3):259–265.
  • Walle T. 2011. Bioavailability of resveratrol. Ann N Y Acad Sci. 1215:9–15.
  • Walle T, Hsieh F, DeLegge MH, Oatis JE, Walle UK. 2004. High absorption but very low bioavailability of oral resveratrol in humans. Drug Metab Dispos. 32(12):1377–1382.
  • Wan L, Sun X, Wang X, Li Y, Yu Q, Guo C. 2011. A stereospecific HPLC method and its application in determination of pharmacokinetics profile of two enantiomers of naringenin in rats. J Chromatogr Sci. 49(4):316–320.
  • Wong CF, Yuen KH, Peh KK. 1999. Formulation and evaluation of controlled release Eudragit buccal patches. Int J Pharm. 178(1):11–22.
  • Wang XQ, Dai JD, Zhang H, Zhang X, Wang JC, Zhang Q. 2008. Absorption mechanism of cyclosporine A loaded pH-sensitive nanoparticles in rats. J Nanosci Nanotechnol. 8(5):2422–2431.
  • Yadav S, Gupta S. 2015. Development and in vitro characterization of docetaxel-loaded ligand appended solid fat nanoemulsions for potential use in breast cancer therapy. Artif Cells Nanomed Biotechnol. 43(2):93–102.
  • Zu Y, Zhang Y, Wang W, Zhao X, Han X, Wang K, Ge Y. 2016. Preparation and in vitro/in vivo evaluation of resveratrol-loaded carboxymethyl chitosan nanoparticles. Drug Deliv. 23(3):981–991.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.