Bilayer nanofibrous wound dressing prepared by electrospinning containing gallic acid and quercetin with improved biocompatibility, antibacterial, and antioxidant effects

References

• Adeli H, Khorasani MT, Parvazinia M. 2019. Wound dressing based on electrospun PVA/chitosan/starch nanofibrous mats: fabrication, antibacterial and cytocompatibility evaluation and in vitro healing assay. Int J Biol Macromol. 122:238–254.
   PubMed Web of Science ®Google Scholar
• Ajmal G, Bonde GV, Mittal P, Khan G, Pandey VK, Bakade BV, Mishra B. 2019. Biomimetic PCL-gelatin based nanofibers loaded with ciprofloxacin hydrochloride and quercetin: a potential antibacterial and anti-oxidant dressing material for accelerated healing of a full thickness wound. Int J Pharm. 567:118480.
   PubMed Web of Science ®Google Scholar
• Asiri A, Saidin S, Sani MH, Al-Ashwal RH. 2021. Epidermal and fibroblast growth factors incorporated polyvinyl alcohol electrospun nanofibers as biological dressing scaffold. Sci Rep. 11(1):5634.
   PubMed Web of Science ®Google Scholar
• Aytimur A, Uslu İ. 2014. Promising materials for wound dressing: PVA/PAA/PVP electrospun nanofibers. Polym Plast Technol Eng. 53(7):655–660.
   Web of Science ®Google Scholar
• Chen K, Pan H, Ji D, Li Y, Duan H, Pan W. 2021. Curcumin-loaded sandwich-like nanofibrous membrane prepared by electrospinning technology as wound dressing for accelerate wound healing. Mater Sci Eng C Mater Biol Appl. 127:112245.
   PubMed Web of Science ®Google Scholar
• Chen R, Salisbury AM, Percival SL. 2019. In vitro cellular viability studies on a concentrated surfactant-based wound dressing. Int Wound J. 16(3):703–712.
   PubMed Web of Science ®Google Scholar
• Chen X, Wang X, Wang S, Zhang X, Yu J, Wang C. 2020. Mussel-inspired polydopamine-assisted bromelain immobilization onto electrospun fibrous membrane for potential application as wound dressing. Mater Sci Eng C Mater Biol Appl. 110:110624.
   PubMed Web of Science ®Google Scholar
• Chinatangkul N, Tubtimsri S, Panchapornpon D, Akkaramongkolporn P, Limmatvapirat C, Limmatvapirat S. 2019. Design and characterisation of electrospun shellac-polyvinylpyrrolidone blended micro/nanofibres loaded with monolaurin for application in wound healing. Int J Pharm. 562:258–270.
   PubMed Web of Science ®Google Scholar
• Choudhary A, Kant V, Jangir BL, Joshi VG. 2020. Quercetin loaded chitosan tripolyphosphate nanoparticles accelerated cutaneous wound healing in Wistar rats. Eur J Pharmacol. 880:173172.
   PubMed Web of Science ®Google Scholar
• Dai T, Tanaka M, Huang YY, Hamblin MR. 2011. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev anti Infect Ther. 9(7):857–879.
   PubMed Web of Science ®Google Scholar
• Demir GC, Erdemli O, Keskin D, Tezcaner A. 2022. Xanthan-gelatin and xanthan-gelatin-keratin wound dressings for local delivery of Vitamin C. Int J Pharm. 614:121436.
   PubMedGoogle Scholar
• Do Pham DD, Jenčová V, Kaňuchová M, Bayram J, Grossová I, Šuca H, Urban L, Havlíčková K, Novotný V, Mikeš P, et al. 2021. Novel lipophosphonoxin-loaded polycaprolactone electrospun nanofiber dressing reduces Staphylococcus aureus induced wound infection in mice. Sci Rep. 11(1):17688.
   PubMed Web of Science ®Google Scholar
• Gomathi K, Gopinath D, Rafiuddin Ahmed M, Jayakumar R. 2003. Quercetin incorporated collagen matrices for dermal wound healing processes in rat. Biomaterials. 24(16):2767–2772.
   PubMed Web of Science ®Google Scholar
• Gouthamchandra K, Mahmood R, Manjunatha H. 2010. Free radical scavenging, antioxidant enzymes and wound healing activities of leaves extracts from Clerodendrum infortunatum L. Environ Toxicol Pharmacol. 30(1):11–18.
   PubMed Web of Science ®Google Scholar
• He J, Liang Y, Shi M, Guo B. 2020. Anti-oxidant electroactive and antibacterial nanofibrous wound dressings based on poly(ε-caprolactone)/quaternized chitosan-graft-polyaniline for full-thickness skin wound healing. Chem Eng J. 385:123464.
   Web of Science ®Google Scholar
• Jarbrink K, Ni G, Sonnergren H, Schmidtchen A, Pang C, Bajpai R, Car J. 2016. Prevalence and incidence of chronic wounds and related complications: a protocol for a systematic review. Syst Rev. 5(1):152.
   PubMedGoogle Scholar
• Kant V, Jangir BL, Kumar V, Nigam A, Sharma V. 2020. Quercetin accelerated cutaneous wound healing in rats by modulation of different cytokines and growth factors. Growth Factors. 38(2):105–119.
   PubMed Web of Science ®Google Scholar
• Kant V, Kumar M, Jangir BL, Kumar V. 2022. Temporal effects of different vehicles on wound healing potentials of quercetin: biochemical, molecular, and histopathological approaches. Int J Low Extrem Wounds. 21(4): 588-600.
   Web of Science ®Google Scholar
• Leu JG, Chen SA, Chen HM, Wu WM, Hung CF, Yao YD, Tu CS, Liang YJ. 2012. The effects of gold nanoparticles in wound healing with antioxidant epigallocatechin gallate and alpha-lipoic acid. Nanomedicine. 8(5):767–775.
   PubMed Web of Science ®Google Scholar
• Li Z, Milionis A, Zheng Y, Yee M, Codispoti L, Tan F, Poulikakos D, Yap CH. 2019. Superhydrophobic hemostatic nanofiber composites for fast clotting and minimal adhesion. Nat Commun. 10(1):5562.
   PubMed Web of Science ®Google Scholar
• Li ZJ, Liu M, Dawuti G, Dou Q, Ma Y, Liu HG, Aibai S. 2017. Antifungal activity of gallic acid in vitro and in vivo. Phytother Res. 31(7):1039–1045.
   PubMed Web of Science ®Google Scholar
• Luraghi A, Peri F, Moroni L. 2021. Electrospinning for drug delivery applications: a review. J Control Release. 334:463–484.
   PubMed Web of Science ®Google Scholar
• Martins A, Araujo JV, Reis RL, Neves NM. 2007. Electrospun nanostructured scaffolds for tissue engineering applications. Nanomedicine. 2(6):929–942.
   PubMed Web of Science ®Google Scholar
• Memic A, Abudula T, Mohammed HS, Joshi Navare K, Colombani T, Bencherif SA. 2019. Latest progress in electrospun nanofibers for wound healing applications. ACS Appl Bio Mater. 2(3):952–969.
   PubMedGoogle Scholar
• Mi Y, Zhong L, Lu S, Hu P, Pan Y, Ma X, Yan B, Wei Z, Yang G. 2022. Quercetin promotes cutaneous wound healing in mice through Wnt/beta-catenin signaling pathway. J Ethnopharmacol. 290:115066.
   PubMed Web of Science ®Google Scholar
• Mirmajidi T, Chogan F, Rezayan AH, Sharifi AM. 2021. In vitro and in vivo evaluation of a nanofiber wound dressing loaded with melatonin. Int J Pharm. 596:120213.
   PubMedGoogle Scholar
• Neo YP, Ray S, Jin J, Gizdavic-Nikolaidis M, Nieuwoudt MK, Liu D, Quek SY. 2013. Encapsulation of food grade antioxidant in natural biopolymer by electrospinning technique: a physicochemical study based on zein-gallic acid system. Food Chem. 136(2):1013–1021.
   PubMed Web of Science ®Google Scholar
• Pandey VK, Ajmal G, Upadhyay SN, Mishra PK. 2020. Nano-fibrous scaffold with curcumin for anti-scar wound healing. Int J Pharm. 589:119858.
   PubMedGoogle Scholar
• Qu J, Zhao X, Liang Y, Zhang T, Ma PX, Guo B. 2018. Antibacterial adhesive injectable hydrogels with rapid self-healing, extensibility and compressibility as wound dressing for joints skin wound healing. Biomaterials. 183:185–199.
   PubMed Web of Science ®Google Scholar
• Ramirez-Barron SN, Sanchez-Valdes S, Betancourt R, Gallardo CA, Puente-Urbina B, Rodriguez-Fernández OS, Carneiro-da Cunha MG, dos Santos- Correia MT, Sanchez-Martinez ZV. 2021. Preparation and characterization of gelatin-gallic acid/ZnO nanocomposite with antibacterial properties as a promising multi-functional bioadhesive for wound dressing applications. Int J Adhes Adhes. 104:102749.
   Web of Science ®Google Scholar
• Rosa RM, Silva JC, Sanches IS, Henriques C. 2017. Simultaneous photo-induced cross-linking and silver nanoparticle formation in a PVP electrospun wound dressing. Mater Lett. 207:145–148.
   Web of Science ®Google Scholar
• Selvaraj S, Fathima NN. 2017. Fenugreek incorporated silk fibroin nanofibers-a potential antioxidant scaffold for enhanced wound healing. ACS Appl Mater Interfaces. 9(7):5916–5926.
   PubMed Web of Science ®Google Scholar
• Shi Y, Li Y, Wu J, Wang W, Dong A, Zhang J. 2014. A novel transdermal drug delivery system based on self-adhesive Janus nanofibrous film with high breathability and monodirectional water-penetration. J Biomater Sci Polym Ed. 25(7):713–728.
   PubMed Web of Science ®Google Scholar
• Simoes D, Miguel SP, Ribeiro MP, Coutinho P, Mendonca AG, Correia IJ. 2018. Recent advances on antimicrobial wound dressing: a review. Eur J Pharm Biopharm. 127:130–141.
   PubMed Web of Science ®Google Scholar
• Stojko M, Włodarczyk J, Sobota M, Karpeta-Jarząbek P, Pastusiak M, Janeczek H, Dobrzyński P, Starczynowska G, Orchel A, Stojko J, et al. 2020. Biodegradable electrospun nonwovens releasing propolis as a promising dressing material for burn wound treatment. Pharmaceutics. 12(9):883.
   PubMed Web of Science ®Google Scholar
• Sun S, Hao M, Ding C, Zhang J, Ding Q, Zhang Y, Zhao Y, Liu W. 2022. SF/PVP nanofiber wound dressings loaded with phlorizin: preparation, characterization, in vivo and in vitro evaluation. Colloids Surf B Biointerfaces. 217:112692.
   PubMed Web of Science ®Google Scholar
• Tamayo L, Santana P, Forero JC, Leal M, Gonzalez N, Diaz M, Guiliani N, Hamm E, Urzua M. 2022. Coaxial fibers of poly(styrene-co-maleic anhydride)@poly(vinyl alcohol) for wound dressing applications: dual and sustained delivery of bioactive agents promoting fibroblast proliferation with reduced cell adherence. Int J Pharm. 611:121292.120.
   PubMedGoogle Scholar
• Thanyacharoen T, Chuysinuan P, Techasakul S, Nooeaid P, Ummartyotin S. 2018. Development of a gallic acid-loaded chitosan and polyvinyl alcohol hydrogel composite: release characteristics and antioxidant activity. Int J Biol Macromol. 107(Pt A):363–370.
   PubMedGoogle Scholar
• Tort S, Demiröz FT, Coşkun Cevher Ş, Sarıbaş S, Özoğul C, Acartürk F. 2020. The effect of a new wound dressing on wound healing: biochemical and histopathological evaluation. Burns. 46(1):143–155.
   PubMed Web of Science ®Google Scholar
• Wang Z, Wang H, Xiong J, Li J, Miao X, Lan X, Liu X, Wang W, Cai N, Tang Y. 2021. Fabrication and in vitro evaluation of PCL/gelatin hierarchical scaffolds based on melt electrospinning writing and solution electrospinning for bone regeneration. Mater Sci Eng C Mater Biol Appl. 128:112287.
   PubMed Web of Science ®Google Scholar
• Xia J, Zhang H, Yu F, Pei Y, Luo X. 2020. Superclear, porous cellulose membranes with chitosan-coated nanofibers for visualized cutaneous wound healing dressing. ACS Appl Mater Interfaces. 12(21):24370–24379.
   PubMed Web of Science ®Google Scholar
• Xu D, Hu MJ, Wang YQ, Cui YL. 2019. Antioxidant activities of quercetin and its complexes for medicinal application. Molecules. 24(6):1123.
   PubMed Web of Science ®Google Scholar
• Yang X, Wang B, Sha D, Liu Y, Liu Z, Shi K, Liu W, Yu C, Ji X. 2021. PVA/poly(hexamethylene guanidine)/gallic acid composite hydrogel films and their antibacterial performance. ACS Appl Polym Mater. 3(8):3867–3877.
   Web of Science ®Google Scholar
• Yang Y, Du Y, Zhang J, Zhang H, Guo B. 2022. Structural and functional design of electrospun nanofibers for hemostasis and wound healing. Adv Fiber Mater. 4(5):1027–1057.
   Google Scholar
• Yoo H-J, Kim H-D. 2008. Characteristics of waterborne polyurethane/poly(N-vinylpyrrolidone) composite films for wound-healing dressings. J Appl Polym Sci. 107(1):331–338.
   Web of Science ®Google Scholar
• Zhang Q, Oh JH, Park CH, Baek JH, Ryoo HM, Woo KM. 2017. Effects of dimethyloxalylglycine-embedded poly(epsilon-caprolactone) fiber meshes on wound healing in diabetic rats. ACS Appl Mater Interfaces. 9(9):7950–7963.
   PubMed Web of Science ®Google Scholar
• Zhao L, Xu L, Mitomo H, Yoshii F. 2006. Synthesis of pH-sensitive PVP/CM-chitosan hydrogels with improved surface property by irradiation. Carbohydr Polym. 64(3):473–480.
   Web of Science ®Google Scholar
• Zhou L, Cai L, Ruan H, Zhang L, Wang J, Jiang H, Wu Y, Feng S, Chen J. 2021. Electrospun chitosan oligosaccharide/polycaprolactone nanofibers loaded with wound-healing compounds of Rutin and Quercetin as antibacterial dressings. Int J Biol Macromol. 183:1145–1154.
   PubMed Web of Science ®Google Scholar