A Comparative Histological Study of Alginate Beads as a Promising Controlled Release Delivery for Mefenamic Acid

REFERENCES

• DL Kaplan, BJ Wiley, JM Mayer, S Arcidiacono, J Keith, SJ Lombardi, D Ball, and AL Allen. Biomedical Polymers SW Shalaby. Hanser Publishers, New York, (1994)189–212.
   Google Scholar
• WR Gombotz, and SF Wee. (1998). Protein release from alginate matrices. Adv. Drug Deliv. Rev. 31:267–285.
   PubMed Web of Science ®Google Scholar
• S Çalıs, B Arıca, HS Kas, and AA Hıncal. 5-Fluorourasil-loaded alginate microspheres in chitosan gel for local therapy of breast cancer. In: Muzzarelli RAA, Muzzarelli C. Chitosan in Pharmacy and Chemistry . Atec, Italy, (2002)65–69.
   Google Scholar
• M Türkoglu, A Gürsoy, L Eroglu, and I Okar. (1997). Effect of aqueous polymer dispersions on properties of diclofenac/alginate beads and in vivo evaluations in rats. STP Pharma Sci. 7:135–140.
   Google Scholar
• CK Kim, and EJ Lee. (1992). The controlled release of blue dextran from alginate beads. Int. J. Pharm. 79:11–19.
   Web of Science ®Google Scholar
• R Bodmeier, and J Wang. (1993). Microencapsulation of drugs with aqueous colloidal polymer dispersions. J. Pharm. Sci. 82:191–194.
   PubMed Web of Science ®Google Scholar
• SJ Hwang, GJ Rhee, KM Lee, KH Oh, and CK Kim. (1995). Release characteristics of ibuprofen from excipient-loaded alginate beads. Int. J. Pharm. 116:125–128.
   Web of Science ®Google Scholar
• AD Sezer, and J Akbuga. (1999). Release characteristics of chitosan treated alginate beads: I. Sustained release of macromolecular drug from chitosan treated alginate beads. J. Microencap. 16:195–203.
   PubMed Web of Science ®Google Scholar
• PD Gaudio, P Colombo, G Colombo, P Russo, and F Sonvico. (2005). Mechanisms of formation and disintegration of alginate beads obtained by prilling. Int. J. Pharm. 302:1–9.
   PubMed Web of Science ®Google Scholar
• P Sriamornsak, and S Sungthongjeen. (2007). Modification of theophylline release with alginate gel formed in hard capsules. AAPS Pharm. Sci. Tech. 8 (3): Article 51.
   Google Scholar
• JEF Reynolds. The complete drug reference Martindale, The Extra Pharmacopoeia32nd K Porfıtt. Pharmaceutical Press, London, (1999)58–59.
   Google Scholar
• European Pharmacopoeia. Strasbourg: Council of Europea. , (2002).
   Google Scholar
• The United States Pharmacopoeia 28 and NF23. United States Pharmacopoeial Convention, Rockville MD, (2005).
   Google Scholar
• FDA/CDER. (August, 2000). Waiver of in vivo bioavailability and bioequivalance studies for immediate release solid oral dosage forms based on a biopharmaceutics classification system. Guidance for Industry
   Google Scholar
• G Kimura, G Betz, and H Leuenberger. (2007). Influence of loading volume of mefenamic acid on granules and tablet characteristics using a compaction simulator. Pharm. Dev. Tech. 12:627–635.
   PubMed Web of Science ®Google Scholar
• TA Tokumura. (2000). A screening system of solubility for drug design and discovery. Pharm. Tech Japan. 16 (13):19–27.
   Google Scholar
• M Yazdanian, K Briggs, C Jankovsky, and A Hawi. (2004). The “high solubility” definition of the current FDA guidance on biopharmaceutical classification system may be too strict for acidic drugs. Pharm. Res. 21 (2):293–299.
   PubMedGoogle Scholar
• Y Joo, H Kim, R Woo, and C Park. (2006). Mefenamic acid shows neuroprotective effects and improves cognitive impairment in in vitro and in vivo Alzheimer's disease models. Mol. Pharm. 69:76–84.
   PubMed Web of Science ®Google Scholar
• A Yurdasiper, B Kaynarsoy, F Sevgi, E Turunç, and A Yalçın. Effect of mefenamic acid and its microsponge formulations on the rat brain cortex DNA Proceedings 13th Inter Pharm Technol Symp AntalyaTurkey, September 10–13, (2006)75–76.
   Google Scholar
• JG Hardman, L Limbird, and A Goodman. Goodman and Gilman's The Pharmacological Basis of Therapeutics10th . McGraw Hill Publishing, Nevada, (2005).
   Google Scholar
• GV Betageri, KR Kurumaddali, and WR Ravis. (1995). Preparation and in vitro evaluation of mefenamic acid sustained release beads. Drug Dev. Ind. Pharm. 21:265–275.
   Web of Science ®Google Scholar
• EM Ramadan, A El-Helw, and Y El-Said. (1987). Effect of encapsulation of mefenamic acid with cationic Eudragit E on its bioavailability and gastric ulcerogenic activity in rabbits. J. Microen. 4:125–132.
   PubMedGoogle Scholar
• K Lalla, and PL Ahuja. (1991). Drug targeting using non-magnetic and magnetic albumin-globulin mix microspheres of mefenamic acid. J. Microen. 8:37–52.
   PubMed Web of Science ®Google Scholar
• A Yurdasiper, B Kaynarsoy, F Sevgi, E Turunç, and A Yalçın. The comparative effects of mefenamic acid microsponge formulations with different polymers on the rat brain cortex DNAAmsterdamThe Netherlands, Pharm Sci World Congress (PSWC), April 22–25(2007)07L–1212.
   Google Scholar
• S Gungor, A Yıldız, Y Ozsoy, E Cevher, and A Araman. (2003). Investigations on mefenamic acid sustained release tablets with water-insoluble gel. Il Farmaco 58:397–401.
   PubMedGoogle Scholar
• N Segi, T Yotsuyanagi, and K Ikeda. (1989). Interaction of calcium-induced alginate gel beads with propranolol. Chem Pharm Bull. 37:3092–3095.
   Web of Science ®Google Scholar
• F Sevgi, M Ozyazıcı, B Kaynarsoy, D Ozyurt, and C Pekçetin. Histological evaluation of drug-loaded alginate beads and Eudragit microspheres, Antalya, Turkey, Proceed 13th Inter Pharm Technol Symp AntalyaTurkey, Sept. 10–13 (2006)135–136.
   Google Scholar
• MSY Khan, and M Akhter. (2005). Glyceride derivatives as potential prodrugs: synthesis, biological activity and kinetic studies of glyceride derivatives of mefenamic acid. Pharmazie 60 (2):110–114.
   PubMedGoogle Scholar
• F Sevgi, B Kaynarsoy, and G Ertan. (2008). An antiinflammatory drug (mefenamic acid) incorporated in biodegradable alginate beads: Development and optimization of the process using factorial design. Pharm. Dev. Tech. 13 (1):5–13.
   PubMedGoogle Scholar
• B Arıca, S Çalıs, P Atilla, NT Durlu, N Çakar, HS Kas, and AA Hıncal. (2005). In vitro and in vivo studies of ibuprofen-loaded biodegradable alginate beads. J. Microen. 22 (2):153–165.
   PubMed Web of Science ®Google Scholar
• H Li, T Miki, H Gu, I Satriotomo, and Y Mastumoto. (2002). The effect of timing of prenatal X-irridation on purkinje cell numbers in rat cerebellum. Develop. Brain Res. 139:159–166.
   PubMedGoogle Scholar
• H Piao, A Hirata, H Yokoyama, T Fujii, I Shimizu, S Ito, N Kamiya, and M Goto. (2007). Reduction of gastric ulcerogenicity during multiple administration of diclofenac sodium by a novel solid-in-oil suspension. Pharm. Dev. Tech. 12:321–325.
   PubMed Web of Science ®Google Scholar
• M Acikgöz, HS Kas, Z Hasçelik, Ü Milli, and AA Hıncal. (1995). Chitosan microspheres of diclofenac sodium. II: In vitro and in vivo evaluation. Pharmazie 50:275–277.
   PubMed Web of Science ®Google Scholar