References

  • Saver JL, Goyal M, van der Lugt A, Menon BK, Majoie CB, Dippel DW, et al. Time to treatment with endovascular thrombectomy and outcomes from ischemic stroke: a meta-analysis. JAMA. 2016; 316(12):1279–88. doi: 10.1001/jama.2016.13647.
  • Fransen PS, Berkhemer OA, Lingsma HF, Beumer D, van den Berg LA, Yoo AJ, et al. Time to reperfusion and treatment effect for acute ischemic stroke: a randomized clinical trial. JAMA Neurol. 2016;73(2):190–196. doi: 10.1001/jamaneurol.2015.3886.
  • Goyal M, Menon BK, van Zwam WH, Dippel DW, Mitchell PJ, Demchuk AM, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials. Lancet. 2016;387(10029):1723–31. doi: 10.1016/S0140-6736(16)00163-X.
  • Prabhakaran S, Ruff I, Bernstein RA. Acute stroke intervention: a systematic review. JAMA. 2015;313(14):1451–62. doi: 10.1001/jama.2015.3058.
  • Richards CT, Adams JG, Prabhakaran S. Recent evidence for endovascular therapy in acute ischemic stroke. Ann Emerg Med. 2015; 66(4):441–2. doi: 10.1016/j.annemergmed.2015.05.022.
  • Medoro I, Cone DC. An analysis of EMS and ED detection of stroke. Prehosp Emerg Care. 2017;21(4):476–80. doi: 10.1080/10903127.2017.1294222.
  • Prabhakaran S, O'Neill K, Stein-Spencer L, Walter J, Alberts MJ. Prehospital triage to primary stroke centers and rate of stroke thrombolysis. JAMA Neurol. 2013;70(9):1126–32. doi: 10.1001/jamaneurol.2013.293.
  • Higashida R, Alberts MJ, Alexander DN, Crocco TJ, Demaerschalk BM, Derdeyn CP, et al. Interactions within stroke systems of care: a policy statement from the American Heart Association/American Stroke Association. Stroke. 2013;44(10):2961–84. doi: 10.1161/STR.0b013e3182a6d2b2.
  • Ekundayo OJ, Saver JL, Fonarow GC, Schwamm LH, Xian Y, Zhao X, Hernandez AF, Peterson ED, Cheng EM. Patterns of emergency medical services use and its association with timely stroke treatment: Findings from Get With the Guidelines-Stroke. Circ Cardiovasc Qual Outcomes. 2013;6(3):262–9. doi: 10.1161/CIRCOUTCOMES.113.000089.
  • Abdullah AR, Smith EE, Biddinger PD, Kalenderian D, Schwamm LH. Advance hospital notification by EMS in acute stroke is associated with shorter door-to-computed tomography time and increased likelihood of administration of tissue-plasminogen activator. Prehosp Emerg Care. 2008;12(4):426–31. doi: 10.1080/10903120802290828.
  • Pride GL, Fraser JF, Gupta R, Alberts MJ, Rutledge JN, Fowler R, et al. Prehospital care delivery and triage of stroke with emergent large vessel occlusion (ELVO): report of the standards and guidelines committee of the Society of Neurointerventional Surgery. J Neurointerv Surg. 2017;9(8):802–810. doi: 10.1136/neurintsurg-2016-012699.
  • Jauch EC, Saver JL, Adams HP, Jr., Bruno A, Connors JJ, Demaerschalk BM, et al. Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2013;44(3):870–947. doi: 10.1161/STR.0b013e318284056a.
  • Caceres JA, Adil MM, Jadhav V, Chaudhry SA, Pawar S, Rodriguez GJ, Suri MF, Qureshi AI. Diagnosis of stroke by emergency medical dispatchers and its impact on the prehospital care of patients. J Stroke Cerebrovasc Dis. 2013;22(8):e610–4. doi: 10.1016/j.jstrokecerebrovasdis.2013.07.039.
  • Abboud ME, Band R, Jia J, Pajerowski W, David G, Guo M, Mechem CC, Messe SR, Carr BG, Mullen MT. Recognition of stroke by EMS is associated with improvement in emergency department quality measures. Prehosp Emerg Care. 2016;20(6):729–36. doi: 10.1080/10903127.2016.1182602.
  • Stiell IG, Clement CM, Campbell K, Sharma M, Socha D, Sivilotti ML, et al. Impact of expanding the prehospital stroke bypass time window in a large geographic region. Stroke. 2017;48(3):624–30. doi: 10.1161/STROKEAHA.116.014868.
  • Milne MS, Holodinsky JK, Hill MD, Nygren A, Qiu C, Goyal M, Kamal N. Drip ‘n ship versus mothership for endovascular treatment: modeling the best transportation options for optimal outcomes. Stroke. 2017;48(3):791–4. doi: 10.1161/STROKEAHA.116.015321.
  • Zaidi SF, Shawver J, Espinosa Morales A, Salahuddin H, Tietjen G, Lindstrom D, Parquette B, Adams A, Korsnack A, Jumaa MA. Stroke care: initial data from a county-based bypass protocol for patients with acute stroke. J Neurointerv Surg. 2017;9(7):631–635. doi: 10.1136/neurintsurg-2016-012476.
  • Mohamad NF, Hastrup S, Rasmussen M, Andersen MS, Johnsen SP, Andersen G, Simonsen CZ. Bypassing primary stroke centre reduces delay and improves outcomes for patients with large vessel occlusion. European Stroke Journal. 2016;1(2):85–92. doi: 10.1177/2396987316647857.
  • Powers WJ, Derdeyn CP, Biller J, Coffey CS, Hoh BL, Jauch EC, et al. 2015 American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke. 2015;46(10):3020–35.
  • Michel P. Prehospital scales for large vessel occlusion: Closing in on a moving target. Stroke. 2017;48(2):247–9.
  • McMullan JT, Katz B, Broderick J, Schmit P, Sucharew H, Adeoye O. Prospective prehospital evaluation of the Cincinnati Stroke Triage Assessment Tool. Prehosp Emerg Care. 2017;21(4):481–8.
  • Perez de la Ossa N, Ribo M, Jimenez X, Abilleira S. Prehospital scales to identify patients with large vessel occlusion: It is time for action. Stroke. 2016;47(11):2877–8.
  • Hastrup S, Damgaard D, Johnsen SP, Andersen G. Prehospital Acute Stroke Severity scale to predict large artery occlusion: design and comparison with other scales. Stroke. 2016;47(7):1772–6.
  • Katz BS, McMullan JT, Sucharew H, Adeoye O, Broderick JP. Design and validation of a prehospital scale to predict stroke severity: Cincinnati Prehospital Stroke Severity Scale. Stroke. 2015;46(6):1508–12.
  • Nazliel B, Starkman S, Liebeskind DS, Ovbiagele B, Kim D, Sanossian N, et al. A brief prehospital stroke severity scale identifies ischemic stroke patients harboring persisting large arterial occlusions. Stroke. 2008;39(8):2264–7.
  • Perez de la Ossa N, Carrera D, Gorchs M, Querol M, Millan M, Gomis M, et al. Design and validation of a prehospital stroke scale to predict large arterial occlusion: The rapid arterial occlusion evaluation scale. Stroke. 2014;45(1):87–91.
  • Zhao H, Coote S, Pesavento L, Churilov L, Dewey HM, Davis SM, Campbell BC. Large vessel occlusion scales increase delivery to endovascular centers without excessive harm from misclassifications. Stroke. 2017;48(3):568–73.
  • Lima FO, Silva GS, Furie KL, Frankel MR, Lev MH, Camargo EC, et al. Field Assessment Stroke Triage for Emergency Destination: a simple and accurate prehospital scale to detect large vessel occlusion strokes. Stroke. 2016;47(8):1997–2002. doi: 10.1161/STROKEAHA.116.013301.
  • Kim JT, Chung PW, Starkman S, Sanossian N, Stratton SJ, Eckstein M, et al. Field validation of the Los Angeles Motor Scale as a tool for paramedic assessment of stroke severity. Stroke. 2017;48(2):298–306. doi: 10.1161/STROKEAHA.116.015247.
  • Carrera D, Campbell BC, Cortes J, Gorchs M, Querol M, Jimenez X, Millan M, Davalos A, Perez de la Ossa N. Predictive value of modifications of the prehospital Rapid Arterial Occlusion Evaluation scale for large vessel occlusion in patients with acute stroke. J Stroke Cerebrovasc Dis. 2017;26(1):74–7. doi: 10.1016/j.jstrokecerebrovasdis.2016.08.032.
  • Southerland AM, Johnston KC, Molina CA, Selim MH, Kamal N, Goyal M. Suspected large vessel occlusion: should emergency medical services transport to the nearest primary stroke center or bypass to a comprehensive stroke center with endovascular capabilities? Stroke. 2016;47(7):1965–7. doi: 10.1161/STROKEAHA.115.011149.
  • Prabhakaran S, Ward E, John S, Lopes DK, Chen M, Temes RE, Mohammad Y, Lee VH, Bleck TP. Transfer delay is a major factor limiting the use of intra-arterial treatment in acute ischemic stroke. Stroke. 2011;42(6):1626–30. doi: 10.1161/STROKEAHA.110.609750.
  • Sun CH, Nogueira RG, Glenn BA, Connelly K, Zimmermann S, Anda K, et al. “Picture to puncture”: a novel time metric to enhance outcomes in patients transferred for endovascular reperfusion in acute ischemic stroke. Circulation. 2013;127(10):1139–48. doi: 10.1161/CIRCULATIONAHA.112.000506.
  • Crocco TJ, Moreno R, Jauch EC, Racine AN, Pio BJ, Liu T, Kothari RU. Teaching ACLS stroke objectives to prehospital providers: a case-based approach. Prehosp Emerg Care. 2003;7(2):229–34. doi: 10.1080/10903120390936833.
  • Kothari RU, Pancioli A, Liu T, Brott T, Broderick J. Cincinnati Prehospital Stroke Scale: reproducibility and validity. Ann Emerg Med. 1999;33(4):373–8. doi: 10.1016/S0196-0644(99)70299-4.
  • You JS, Chung SP, Chung HS, Lee HS, Park JW, Kim HJ, Lee SH, Park I. Predictive value of the Cincinnati Prehospital Stroke Scale for identifying thrombolytic candidates in acute ischemic stroke. Am J Emerg Med. 2013;31(12):1699–702. doi: 10.1016/j.ajem.2013.08.029.
  • Sangha RS, Caprio FZ, Askew R, Corado C, Bernstein R, Curran Y, Ruff I, Cella D, Naidech AM, Prabhakaran S. Quality of life in patients with TIA and minor ischemic stroke. Neurology. 2015;85(22):1957–63. doi: 10.1212/WNL.0000000000002164.
  • Maas MB, Furie KL, Lev MH, Ay H, Singhal AB, Greer DM, Harris GJ, Halpern E, Koroshetz WJ, Smith WS. National Institutes of Health Stroke Scale score is poorly predictive of proximal occlusion in acute cerebral ischemia. Stroke. 2009;40(9):2988–93. doi: 10.1161/STROKEAHA.109.555664.
  • Cooray C, Fekete K, Mikulik R, Lees KR, Wahlgren N, Ahmed N. Threshold for NIH stroke scale in predicting vessel occlusion and functional outcome after stroke thrombolysis. Int J Stroke. 2015;10(6):822–9. doi: 10.1111/ijs.12451.
  • Vahedi K, Hofmeijer J, Juettler E, Vicaut E, George B, Algra A, et al. Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials. Lancet Neurol. 2007;6(3):215–22. doi: 10.1016/S1474-4422(07)70036-4.
  • Greiner M, Pfeiffer D, Smith RD. Principles and practical application of the receiver-operating characteristic analysis for diagnostic tests. Prev Vet Med. 2000;45(1):23–41. doi: 10.1016/S0167-5877(00)00115-X.
  • Youden WJ. Index for rating diagnostic tests. Cancer. 1950;3(1):32–35. doi: 10.1002/1097-0142(1950)3:1%3c32::AID-CNCR2820030106%3e3.0.CO;2-3.
  • Fluss R, Faraggi D, Reiser B. Estimation of the Youden index and its associated cutoff point. Biometrical Journal. 2005;47(4):458–72. doi: 10.1002/bimj.200410135.
  • Cicchetti DV. Guidelines, criteria, and rules of thumb for evaluating normed and standardized assessment instruments in psychology. Psychological assessment. 1994;6(4):284. doi: 10.1037/1040-3590.6.4.284.
  • Sequeira D, Martin-Gill C, Kesinger MR, Thompson LR, Jovin TG, Massaro LM, Guyette FX. Characterizing strokes and stroke mimics transported by helicopter emergency medical services. Prehosp Emerg Care. 2016;20(6):723–8. doi: 10.3109/10903127.2016.1168889.
  • Goyal M, Menon BK, van Zwam WH, Dippel DW, Mitchell PJ, Demchuk AM, et al. Endovascular thrombectomy after large-vessel ischaemic stroke: A meta-analysis of individual patient data from five randomised trials. Lancet. 2016;387(10029):1723–1731. doi: 10.1016/S0140-6736(16)00163-X.
  • Christou I, Burgin WS, Alexandrov AV, Grotta JC. Arterial status after intravenous TPA therapy for ischaemic stroke. A need for further interventions. Int Angiol. 2001;20(3):208–13.
  • Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R, et al. Heart disease and stroke statistics-2017 update: a report from the American Heart Association. Circulation. 2017;135(10):e146–e603. doi: 10.1161/CIR.0000000000000485.

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