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Original Articles

Growth inhibitory and cytotoxic effects of three arsenic compounds on cultured Chinese hamster ovary cells

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Pages 37-72 | Received 14 May 1984, Accepted 11 Jul 1984, Published online: 15 Dec 2008

References

  • Pershagen , G. and Vahter , M. 1979 . Aarsenic—a toxicological and epidemiological appraisal , Stockholm : National (Swedish) Environment Protection Board . SNV PM 1128.
  • Landrigan , P.J. 1981 . Arsenic—state of the art . Am. J. Indust. Med. , 2 : 5 – 14 .
  • Scherf , H.R. and Dietrich , S. 1983 . Possibilities and limits of prevention of cancer induced by environmental carcinogens . J. Environ. Sci. Health , C1 : 233 – 261 .
  • Furst , A. 1983 . “ A new look at arsenic carcinogenesis ” . In “Arsenic: Industrial, Biomedical and Environmental Perspectives” , Edited by: Lederer , W.H. and Sensterheim , R.J. 151 – 165 . New York : Van Nostrand Reinhold Co. .
  • Léonard , A. and Lauwerys , R.R. 1980 . Carcinogenicity, teratogenicity and mutagenicity of arsenic . Mutation Res. , 75 : 49 – 62 .
  • Rossman , T.G. 1981 . Enhancement of UV‐mutagenesis by low concentrations of arsenite in E. coli. . Mutation Res. , 91 : 207 – 211 .
  • Wen , W.N. , Lieu , T.‐L. , Chang , H.‐J. , Wuu , S.W. , Yau , M.‐L. and Jau , K.Y. 1981 . Baseline and sodium‐arsenite‐induced sister chromatid exchanges in cultured lymphocytes from patients with blackfoot disease and healthy persons . Human Genet. , 59 : 201 – 203 .
  • Wan , B. , Christian , R.T. and Soukup , S.W. 1982 . Studies of cytogenetic effects of sodium arsenicals on mammalian cells in vitro, Environ . Mutagenesis , 4 : 493 – 498 .
  • Castro , B.C. , Meyers , J. and DiPaolo , J.A. 1979 . Enhancement of viral transformation for evaluation of the carcinogenic or mutagenic potential of inorganic salts . Cancer Res. , 39 : 193 – 198 .
  • Ohno , H. , Hanaoka , F. and Yamada , M. 1982 . Inducibility of sister‐chromatid exchanges by heavy‐metal ions . Mutation Res. , 104 : 141 – 145 .
  • Vouk , V.B. and Piver , W.T. 1983 . Metallic elements in fossil fuel combustion products: amounts and forms of emissions and evaluation of carcinogenicity and mutagenicity . Environ. Health Persp. , 47 : 201 – 225 .
  • Rossman , T.G. , Stone , D. , Molina , M. and Troll , W. 1981 . Absence of arsenic mutagenicity in E. coli and Chinese hamster cells, Environ . Mutagenesis , 2 : 371 – 379 .
  • Oberly , T.J. , Piper , C.E. and McDonald , D.S. 1982 . Mutagenicity of metal salts in the L5178Y mouse lymphoma assay . J. Toxicol. Environ. Health , 9 : 367 – 376 .
  • Braman , R.S. and Foreback , C.C. 1973 . Methylated forms of arsenic in the environment . Science , 182 : 1247 – 1249 .
  • Lemmo , N.V. , Faust , S.D. , Belton , T. and Tucker , R. 1983 . Assessment of the chemical and biological significance of arsenical compounds in a heavily contaminated watershed. Part 1. The fate and speciation of arsenical compounds in aquatic environments—A literature review . J. Environ. Sci. Health , A18 : 335 – 387 .
  • Hall , L.W. Jr. and Burton , D.T. 1982 . Effects of power plant coal pile and coal waste runoff and leachate on aquatic biota: an overview with research recommendations . CRC Critical Reviews in Toxicology , 10 : 287 – 302 .
  • Yamauchi , H. and Yamamura , Y. 1983 . Concentration and chemical species of arsenic in human tissue . Bull. Environ. Contain. Toxicol. , 31 : 267 – 277 .
  • Crecelius , E.A. 1977 . Changes in the chemical speciation of arsenic following ingestion by man . Environ. Health Persp. , 19 : 147 – 150 .
  • Smith , T.J. , Crecelius , E.A. and Reading , J.C. 1977 . Airborne arsenic exposure and excretion of methylated arsenic compounds . Environ. Health Persp. , 19 : 89 – 93 .
  • Tam , G.K.H. , Charbonneau , S.M. , Lacroix , G. and Bryce , F. 1979 . Confirmation of inorganic arsenic and dimethylarsinic acid in urine and plasma of dog by ion‐exchange and TLC . Bull. Environ. Contam. Toxicol. , 21 : 371 – 374 .
  • Buchet , J.P. , Lauwerys , R. and Roels , H. 1981 . Comparison of the urinary excretion of arsenic metabolites after a single oral dose of sodium arsenite, monomethylarsonate or dimethylarsinate in man . Int. Arch. Occup. Environ. Health , 48 : 71 – 79 .
  • Vahter , M. 1981 . Biotransformation of trivalent and pentavalent inorganic arsenic in mice and rats . Environ. Res. , 25 : 286 – 293 .
  • Lasko , J. and Peoples , S.A. 1975 . Methylation of inorganic arsenic by mammals . Agr. Food Chem. , 23 : 674 – 676 .
  • Odanaka , Y. , Matano , O. and Goto , S. 1980 . Biomethylation of inorganic arsenic by the rat and some laboratory animals . Bull. Environ. Contain. Toxicol. , 24 : 452 – 459 .
  • Charbonneau , S.M. , Tarn , G.K.H. , Bryce , F. , Zawidzka , Z. and Sandi , E. 1979 . Metabolism of orally administered arsenic in the dog . Toxicol. Lett. , 3 : 107 – 113 .
  • Klaassen , C.D. 1974 . Biliary excretion of arsenic in rats, rabbits, and dogs, Toxicol . Appl. Pharmacol. , 29 : 447 – 457 .
  • Lerman , S.A. , Clarkson , T.W. and Gerson , R.J. 1983 . Arsenic uptake and metabolism by liver cells is dependent on arsenic oxidation state . Chem. Biol. Interactions , 45 : 401 – 406 .
  • Ginsburg , J.M. 1965 . Renal mechanism for excretion and transformation of arsenic in the dog . Am. J. Physiol. , 208 : 832 – 940 .
  • Tsukamoto , H. , Parker , H.R. and Peoples , S.A. 1983 . Metabolism and renal handling of sodium arsenate in dogs . Am. J. Vet. Res. , 44 : 2331 – 2335 .
  • Fairchild , E.J. , Lewis , R.J. and Tatken , R.L. 1977 . Registry of Toxic Effects of Chemical Substances, U.S. Department of Health, Education, and Welfare , Cincinnati, OH : NIOSH .
  • Subcommittee on Arsenic . 1977 . Medical and Biological effects of Environmental Pollutants Series , Washington, D.C. : National Academy of Sciences .
  • Marafante , E. , Bertolero , F. , Edel‐Rade , J. , Pietra , R. and Sabbioni , E. 1982 . Intracellular interaction and biotransformation of arsenite in rats and rabbits . Sci. Total Environ. , 24 : 27 – 39 .
  • Stevens , J.T. , Hall , L.L. , Farmer , J.D. , DiPasquale , L.C. , Chernoff , N. and Durham , W.F. 1977 . Disposition of 14C‐ and/or As‐cacodylic acid in rats after intravenous, intratracheal, or peroral administration . Environ. Health Perspect. , 19 : 151 – 157 .
  • Woolson , E.A. 1975 . “Arsenical Pesticides” , Edited by: Woolson , E.A. Washington, D.C. : American Chemical Society .
  • Rein , K.A. , Borrebeck , B. and Breiner , J. 1979 . Arsenite inhibits beta‐oxidation in isolated rat liver mitochondria . Biochem. Biophys. Acta , : 574 487 – 494 .
  • Fowler , B.A. , Woods , J.S. and Schiller , C.M. 1979 . Studies of hepatic mitochondrial structure and function: morphometric and biochemical evaluation of in vivo perturbation by arsenate . Lab. Invest. , 41 : 313 – 320 .
  • Harvey , S.G. 1975 . “ Heavy metals ” . In “The Pharmocological Basis of Therapeutics” , Edited by: Goodman , L.S. and Gilman , A. 924 – 938 . New York : Macmillan .
  • Schiller , C.M. , Fowler , B.A. and Woods , J.S. 1977 . Effects of arsenic on pyruvate dehydrogenase activity . Environ. Health Perspect , 19 : 205 – 207 .
  • Kyle , R.A. and Pease , G.L. 1965 . Hematologic aspects of arsenic intoxication . New Engl. J. Med. , 273 : 18 – 23 .
  • Westhoff , D.D. , Samaha , R.J. and Barnes , A. Jr. 1975 . Arsenic intoxication as a cause of megaloblastic anemia . Blood , 45 : 241 – 246 .
  • Feussner , J.R. , Shelburne , J.D. , Bredehoeft , S. and Cohen , H.J. 1979 . Arsenic‐induced bone marrow toxicity: ultrastructural and electron‐probe analysis . Blood , 53 : 820 – 827 .
  • Van Tongeren , J.H.M. , Kunst , A. , Majoor , C.L.H. and Schillings , P.H.M. 1965 . Folic‐acid deficiency in chronic arsenic poisoning . Lancet , 1 : 784 – 786 .
  • Skipper , H.E. , Mitchell , J.H. Jr. , Bennett , L.L. Jr. , Newton , M.A. , Simpson , L. and Eidson , M. 1951 . Observations on inhibition of nucleic acid synthesis resulting from administration of nitrogen mustard, urethan, colchicine, 2,6‐diaminopurine, 8‐azaguanine, potassium arsenite, and cortisone . Cancer Res. , 11 : 145 – 150 .
  • Morse , B.S. , Conlan , M. , Giuliani , D.G. and Nussbaum , M. 1980 . Mechanism of arsenic‐induced inhibition of erythropoiesis in mice . Am. J. Hematol. , 8 : 273 – 280 .
  • Petres , J. and Berger , A. 1972 . Zum Einfluss anorganischen Arsens auf die DNS‐Synthese menschlicher Lymphocyten in vitro . Arch. Dermatol. Forsch , 242 : 343 – 347 .
  • Kao , F.‐T. and Puck , T.T. 1967 . Genetics of somatic mammalian cells. IV. Properties of Chinese hamster cell mutants with respect to the requirement for proline . Genetics , 55 : 513 – 524 .
  • Taylor , R.T. and Hanna , M.L. 1975 . Folate‐dependent enzymes in cultured Chinese hamster ovary cells: induction of 5‐methyltetrahydrofolate homocysteine cobalamin methyltransferase by folate and methionine . Arch. Biochem. Biophys. , 171 : 507 – 520 .
  • Taylor , R.T. and Hanna , M.L. 1982 . Folate‐dependent enzymes in cultured Chinese hamster ovary cells: impaired mitochondrial serine hydroxymethyltransferase activity in two additional glycine‐auxotroph complementation classes . Arch. Biochem. Biophys. , 217 : 609 – 623 .
  • Spurr , A.R. 1969 . A low‐viscosity epoxy resin embedding medium for electron microscopy . J. Ultrast. Res. , 26 : 31 – 43 .
  • Bencosme , S.A. , Stone , R.S. , Latta , H. and Madden , S.C. 1959 . A rapid method for localization of tissue structures or lesions for electron microscopy . J. Biophys. Biochem. Cytol. , 5 : 508 – 511 .
  • Hayat , M.A. 1972 . “Basic Electron Microscopy Technique” , New York : Van Nostrand Reinhold Co. .
  • Reynolds , E.S. 1963 . The use of lead citrate at high pH as an electron‐opaque stain in electron microscopy . J. Cell Biol. , 17 : 208 – 213 .
  • Shane , B. and Stokstad , E.L.R. 1983 . The interrelationship among folate, vitamin B12 and methionine metabolism . Adv. in Nutrition Res. , 5 : 133 – 170 .
  • Peoples , S.A. 1975 . Review of arsenical pesticides . Am. Chem. Soc. Sympos. Ser. , 7 : 1 – 12 .
  • Sorensen , E.M.B. , Smith , N.K.R. and Ramirez‐Mitchell , R. 1982 . Electron probe X‐ray microanalysis of arsenic inclusions in fish . Arch. Environ. Contam. Toxicol. , 11 : 469 – 473 .
  • Fowler , B.A. and Woods , J.S. 1979 . The effects of prolonged oral arsenate exposure on liver mitochondria of mice: morphometric and biochemical studies . Toxicol. and Applied Pharm. , 50 : 177 – 187 .
  • Bertolero , F. , Marafante , E. , Rode , J.E. , Pietra , R. and Sabbioni , E. 1981 . Biotransformations and intracellular binding of arsenic in tissues of rabbits after intraperitoneal administration of 74As labelled arsenite . Toxicology , 20 : 35 – 44 .
  • Sorensen , E.M.B. , Henry , R.E. and Ramirez‐Mitchell , R. 1979 . Time‐dependent localization of arsenic in subcellular liver fractions . J. Environ. Path. Tox. , 2 : 1161 – 1171 .
  • Vahter , M. , Marafante , E. , Lindgren , A. and Dencker , L. 1982 . Tissue distribution and subcellular binding of arsenic in marmoset monkeys after injection of 74As‐Arsenite . Arch. Tox. , 51 : 65 – 77 .
  • Fowler , B.A. , Woods , J.S. and Schiller , C.M. 1977 . Ultra‐structural and biochemical effects of prolonged oral arsenic exposure on liver mitochondria of rats . Environ. Health Perspect. , 19 : 197 – 204 .
  • Stone , O.J. 1969 . The effect of arsenic on inflammation, infection and carcinogenicity . Tex. State J. Med. , 65 : 40 – 43 .
  • Barnes , J.M. and Magos , L. 1968 . Toxicology of organometallic compounds . Organ Chem. Rev. , 3 : 137 – 150 .
  • Clarkson , T.W. 1977 . Factors involved in heavy metal poisoning . Fed. Proc. , 36 : 1634 – 1639 .
  • Roderer , G. 1982 . “ Biological effects of inorganic and organic compounds of mercury, lead, tin, arsenic ” . In “Trace Substances in Environmental Health XVI” , Edited by: Hemphill , D.D. 137 – 144 . Columbia : Univ. Missouri Press .
  • Dustin , A.P. and Piton , R.O. 1929 . Êtudes ser les poisons caryoclasiques les actions cellulaires déclenchées par les composés arsenicaux . Bull. Arch. Roy. de Med. Belgique , 9 : 26 – 35 .
  • King , H. and Ludford , R.J. 1950 . The relation between contribution of arsenicals and cell division . J. Chem. Soc. , 8 : 2086 – 2088 .
  • Author to whom correspondence should be addressed.

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