Increased levels of lead in the blood and frequencies of lymphocytic micronucleated binucleated cells among workers from an electronic-waste recycling site

References

• Wong , C. S. , Wu , S. C. , Duzgoren-Aydin , N.S. , Aydin , A. and Wong , M. H. 2007 . Trace metal contamination of sediments in an e-waste processing village in China . Environ. Pollut. , 145 ( 2 ) : 434 – 442 .
   PubMed Web of Science ®Google Scholar
• Niu , X. and Li , Y. 2007 . Treatment of waste printed wire boards in electronic waste for safe disposal . J. Hazard Mater. , 145 ( 3 ) : 410 – 416 .
   PubMedGoogle Scholar
• Wong , C. S. , Duzgoren-Aydin , N.S. , Aydin , A. and Wong , M. H. 2007 . Evidence of excessive releases of metals from primitive e-waste processing in Guiyu, China . Environ. Pollut. , 148 ( 1 ) : 62 – 72 .
   PubMed Web of Science ®Google Scholar
• Sharma , R. K. and Agrawal , M. 2005 . Biological effects of heavy metals: an overview . J. Environ. Biol. , 26 ( 2 Suppl ) : 301 – 313 .
   PubMed Web of Science ®Google Scholar
• Garza , A. , Vega , R. and Soto , E. 2006 . Cellular mechanisms of lead neurotoxicity . Med. Sci. Monit. , 12 ( 3 ) : 57 – 65 .
   Google Scholar
• Danzeisen , R. , Araya , M. , Harrison , B. , Keen , C. , Solioz , M. , Thiele , D. and McArdle , H.J. 2007 . How reliable and robust are current biomarkers for copper status? . Brit. J. Nutr. , 98 ( 4 ) : 676 – 683 .
   PubMedGoogle Scholar
• Bertin , G. and Averbeck , D. 2006 . Cadmium: cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review) . Biochimie , 88 ( 11 ) : 1549 – 1559 .
   PubMed Web of Science ®Google Scholar
• Wang , T. , Fu , J. , Wang , Y. , Liao , C. , Tao , Y. and Jiang , G. 2009 . Use of scalp hair as indicator of human exposure to heavy metals in an electronic waste recycling area. Environ . Pollut. , 157 ( 8–9 ) : 2445 – 2451 .
   PubMed Web of Science ®Google Scholar
• Wang , J. P. and Guo , X. K. 2006 . Impact of electronic wastes recycling on environmental quality . Biomed. Environ. Sci. , 19 ( 2 ) : 137 – 142 .
   PubMedGoogle Scholar
• Garcia-Leston , J. , Mendez , J. , Pasaro , E. and Laffon , B. 2010 . Genotoxic effects of lead: an updated review . Environ. Int. , 36 ( 6 ) : 623 – 636 .
   PubMed Web of Science ®Google Scholar
• Alghazal , M. A. , Sutiakova , I. , Kovalkovicova , N. , Legath , J. , Falis , M. , Pistl , J. , Sabo , R. , Benova , K. , Sabova , L. and Vaczi , P. 2008 . Induction of micronuclei in rat bone marrow after chronic exposure to lead acetate trihydrate . Toxicol. Ind. Health , 24 ( 9 ) : 587 – 593 .
   PubMedGoogle Scholar
• Celik , A. , Ogenler , O. and Comelekoglu , U. 2005 . The evaluation of micronucleus frequency by acridine orange fluorescent staining in peripheral blood of rats treated with lead acetate . Mutagenesis , 20 ( 6 ) : 411 – 415 .
   PubMed Web of Science ®Google Scholar
• Minozzo , R. , Deimling , L. I. , Gigante , L. P. and Santos-Mello , R. 2004 . Micronuclei in peripheral blood lymphocytes of workers exposed to lead . Mutat. Res. , 565 ( 1 ) : 53 – 60 .
   PubMed Web of Science ®Google Scholar
• Minozzo , R. , Deimling , L. I. and Santos-Mello , R. 2010 . Cytokinesis-blocked micronucleus cytome and comet assays in peripheral blood lymphocytes of workers exposed to lead considering folate and vitamin B12 status . Mutat. Res. , 697 ( 1–2 ) : 24 – 32 .
   PubMedGoogle Scholar
• Khan , M. I. , Ahmad , I. , Mahdi , A. A. , Akhtar , M. J. , Islam , N. , Ashquin , M. and Venkatesh , T. 2010 . Elevated blood lead levels and cytogenetic markers in buccal epithelial cells of painters in India: genotoxicity in painters exposed to lead containing paints . Environ. Sci. Pollut. Res. Int. , 17 ( 7 ) : 1347 – 1354 .
   PubMedGoogle Scholar
• Fenech , M. 1993 . The cytokinesis-block micronucleus technique and its application to genotoxicity studies in human populations . Environ. Health Perspect. , 101 ( Suppl 3 ) : 101 – 107 .
   PubMed Web of Science ®Google Scholar
• Mielzynska , D. , Siwinska , E. , Kapka , L. , Szyfter , K. , Knudsen , L. E. and Merlo , D. F. 2006 . The influence of environmental exposure to complex mixtures including PAHs and lead on genotoxic effects in children living in Upper Silesia, Poland . Mutagenesis , 21 ( 5 ) : 295 – 304 .
   PubMedGoogle Scholar
• Zheng , L. , Wu , K. , Li , Y. , Qi , Z. , Han , D. , Zhang , B. , Gu , C. , Chen , G. , Liu , J. , Chen , S. , Xu , X. and Huo , X. 2008 . Blood lead and cadmium levels and relevant factors among children from an e-waste recycling town in China . Environ. Res. , 108 ( 1 ) : 15 – 20 .
   PubMed Web of Science ®Google Scholar
• Bi , X. , Thomas , G. O. , Jones , K. C. , Qu , W. , Sheng , G. , Martin , F. L. and Fu , J. 2007 . Exposure of electronics dismantling workers to polybrominated diphenyl ethers, polychlorinated biphenyls, and organochlorine pesticides in South China . Environ. Sci. Technol. , 41 ( 16 ) : 5647 – 5653 .
   PubMed Web of Science ®Google Scholar
• Wang , X. , Bi , X. , Sheng , G. and Fu , J. 2006 . Hospital indoor PM10/PM2.5 and associated trace elements in Guangzhou, China . Sci. Total Environ. , 366 ( 1 ) : 124 – 135 .
   PubMed Web of Science ®Google Scholar
• Xu , B. H. and Yan , H. F. 2003 . Mornitoring methods for harzard chemicals at work place , 306 – 307 . Beijing : The Chinese People's Public Security University Publishing House .
   Google Scholar
• Yuan , J. , Chen , L. , Chen , D. , Guo , H. , Bi , X. , Ju , Y. , Jiang , P. , Shi , J. , Yu , Z. , Yang , J. , Li , L. , Jiang , Q. , Sheng , G. , Fu , J. , Wu , T. and Chen , X. 2008 . Elevated serum polybrominated diphenyl ethers and thyroid-stimulating hormone associated with lymphocytic micronuclei in Chinese workers from an E-waste dismantling site . Environ. Sci. Technol. , 42 ( 6 ) : 2195 – 2200 .
   PubMed Web of Science ®Google Scholar
• Fenech , M. , Chang , W. P. , Kirsch-Volders , M. , Holland , N. , Bonassi , S. and Zeiger , E. 2003 . HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures . Mutat. Res. , 534 ( 1–2 ) : 65 – 75 .
   PubMed Web of Science ®Google Scholar
• Zheng , G. J. , Leung , A. O. , Jiao , L. P. and Wong , M. H. 2008 . Polychlorinated dibenzo-p-dioxins and dibenzofurans pollution in China: Sources, environmental levels and potential human health impacts . Environ. Int. , 34 ( 7 ) : 1050 – 1061 .
   PubMed Web of Science ®Google Scholar
• Leung , A. O. , Duzgoren-Aydin , N.S. , Cheung , K. C. and Wong , M. H. 2008 . Heavy metals concentrations of surface dust from e-waste recycling and its human health implications in southeast China . Environ. Sci. Technol. , 42 ( 7 ) : 2674 – 2680 .
   PubMed Web of Science ®Google Scholar
• Huo , X. , Peng , L. , Xu , X. , Zheng , L. , Qiu , B. , Qi , Z. , Zhang , B. , Han , D. and Piao , Z. 2007 . Elevated blood lead levels of children in Guiyu, an electronic waste recycling town in China . Environ. Health Perspect. , 115 ( 7 ) : 1113 – 1117 .
   PubMed Web of Science ®Google Scholar
• Wong , M. H. , Wu , S. C. , Deng , W. J. , Yu , X. Z. , Luo , Q. , Leung , A. O. , Wong , C. S. , Luksemburg , W. J. and Wong , A. S. 2007 . Export of toxic chemicals - A review of the case of uncontrolled electronic-waste recycling . Environ. Pollut. , 149 ( 2 ) : 131 – 140 .
   PubMed Web of Science ®Google Scholar
• 2007 . Toxicological Profile for Lead , Agency for Toxic Substances and Disease Registry . http://www.atsdr.cdc.gov/ToxProfiles/tp13.pdf
   Google Scholar
• Yantasee , W. , Lin , Y. , Hongsirikarn , K. , Fryxell , G. E. , Addleman , R. and Timchalk , C. 2007 . Electrochemical sensors for the detection of lead and other toxic heavy metals: the next generation of personal exposure biomonitors . Environm. Health Perspect. , 115 ( 12 ) : 1683 – 1690 .
   PubMedGoogle Scholar
• Grover , P. , Rekhadevi , P. V. , Danadevi , K. , Vuyyuri , S. B. , Mahboob , M. and Rahman , M. F. 2010 . Genotoxicity evaluation in workers occupationally exposed to lead . Int. J. Hyg. Environ. Health , 213 ( 2 ) : 99 – 106 .
   PubMedGoogle Scholar
• Kosnett , M. J. , Wedeen , R. P. , Rothenberg , S. J. , Hipkins , K. L. , Materna , B. L. , Schwartz , B. S. , Hu , H. and Woolf , A. 2007 . Recommendations for medical management of adult lead exposure . Environ. Health Perspect. , 115 ( 3 ) : 463 – 471 .
   PubMed Web of Science ®Google Scholar
• Navas-Acien , A. , Guallar , E. , Silbergeld , E. K. and Rothenberg , S. J. 2007 . Lead exposure and cardiovascular disease–a systematic review . Environ. Health Perspect. , 115 ( 3 ) : 472 – 482 .
   PubMed Web of Science ®Google Scholar
• Olsson , I. M. , Bensryd , I. , Lundh , T. , Ottosson , H. , Skerfving , S. and Oskarsson , A. 2002 . Cadmium in blood and urine–impact of sex, age, dietary intake, iron status, and former smoking–association of renal effects . Environ. Health Perspect. , 110 ( 12 ) : 1185 – 1190 .
   PubMed Web of Science ®Google Scholar
• Christensen , J. M. 1995 . Human exposure to toxic metals: factors influencing interpretation of biomonitoring results . Sci. Total Environ. , 166 : 89 – 135 .
   PubMed Web of Science ®Google Scholar
• 2008 . Toxicological profile for Cadmiumum , Agency for Toxic Substances and Disease Registry . http://www.atsdr.cdc.gov/toxprofiles/tp.asp?id=48&tid=15
   Google Scholar
• Viaene , M. K. , Roels , H. A. , Leenders , J. , De Groof , M. , Swerts , L. J. , Lison , D. and Masschelein , R. 1999 . Cadmium: a possible etiological factor in peripheral polyneuropathy . Neurotoxicology , 20 ( 1 ) : 7 – 16 .
   PubMedGoogle Scholar
• Engstrom , A. , Michaelsson , K. , Suwazono , Y. , Wolk , A. , Vahter , M. and Akesson , A. 2010 . Long-term cadmium exposure and the association with bone mineral density and fractures in a population-based study among women . J. Bone Miner. Res. , Epub ahead of print.
   Google Scholar
• Tang , X. L. 2006 . Cadmium pollution , 187 – 188 . The Chinese People's Public Health Publishing House: Beijing .
   Google Scholar
• Bolognesi , C. , Landini , E. , Roggieri , P. , Fabbri , R. and Viarengo , A. 1999 . Genotoxicity biomarkers in the assessment of heavy metal effects in mussels: experimental studies . Environ. Mol. Mutagen. , 33 ( 4 ) : 287 – 292 .
   PubMedGoogle Scholar
• Moller , P. 2006 . The alkaline comet assay: towards validation in biomonitoring of DNA damaging exposures . Basic Clin. Pharmacol. Toxicol. , 98 ( 4 ) : 336 – 345 .
   PubMed Web of Science ®Google Scholar
• Araya , M. , Olivares , M. , Pizarro , F. , Gonzalez , M. , Speisky , H. and Uauy , R. 2003 . Copper exposure and potential biomarkers of copper metabolism . Biometals , 16 ( 1 ) : 199 – 204 .
   PubMedGoogle Scholar
• Harvey , L. J. , Majsak-Newman , G. , Dainty , J. R. , Lewis , D. J. , Langford , N. J. , Crews , H. M. and Fairweather-Tait , S.J. 2003 . Adaptive responses in men fed low- and high-copper diets . Brit. J. Nutr. , 90 ( 1 ) : 161 – 168 .
   PubMedGoogle Scholar
• Wilson , L . 2010 . Copper toxicity syndrome , The Center for Development . http://www.drlwilson.com/articles/copper_toxicity_syndrome.htm
   Google Scholar
• Twomey , P. J. , Viljoen , A. , House , I. M. , Reynolds , T. M. and Wierzbicki , A. S. 2005 . Relationship between serum copper, ceruloplasmin, and non-ceruloplasmin-bound copper in routine clinical practice . Clin. Chem. , 51 ( 8 ) : 1558 – 1559 .
   PubMed Web of Science ®Google Scholar