Review: Pharmacological Pollution in Water

REFERENCES

• Kolpin , D. W. U.S. Geological Survey. Personal communication . November 23, 2010
   Google Scholar
• Daughton , C. G. and Ternes , T. A. 1999 . Pharmaceuticals and personal care products in the environment: Agents of subtle change? . Environmental Health Perspectives , 107 : 907 – 938 .
   PubMed Web of Science ®Google Scholar
• Muñoz , I. , Gómez , M. J. , Molina-Díaz , A. , Huijbregts , M. A. J. , Fernández-Alba , A. R. and García-Calvo , E. 2008 . Ranking potential impacts of priority and emerging pollutants in urban wastewater through life cycle impact assessment . Chemosphere , 74 : 37 – 44 .
   PubMed Web of Science ®Google Scholar
• Snyder , S. A. , Westerhoff , P. , Yoon , Y. and Sedlak , D. L. 2003 . Pharmaceuticals, personal care products, and endocrine disruptors in water: Implications for the water industry . Environmental Engineering Science , 20 : 449 – 469 .
   Web of Science ®Google Scholar
• Daughton , C. G. 2003 . Cradle-to-cradle stewardship of drugs for minimizing their environmental disposition while promoting human health. I. Rationale for and avenues toward a green pharmacy . Environmental Health Perspectives , 111 : 757 – 774 .
   PubMed Web of Science ®Google Scholar
• U.S. Environmental Protection Agency . 2009 . Drinking water contaminant candidate list 3—final EPA-HQ-OW-2007-1189 FRL-8963-6
   Google Scholar
• Daughton , C. G. 2001 . Pharmaceuticals and personal care products in the environment: Overarching issues and overview . ACS Symposium Series , 791 : 2 – 38 .
   Google Scholar
• Halling-Sørensen , B. , Nors-Nielsen , S. , Lanzky , P. F. , Ingerslev , F. , Holten-Lützhøft , H. C. and Jørgensen , S. E. 1998 . Occurrence, fate and effects of pharmaceutical substances in the environment: A review . Chemosphere , 36 : 357 – 393 .
   PubMed Web of Science ®Google Scholar
• Phillips , P. J. , Smith , S. G. , Kolpin , D. W. , Zaugg , S. D. , Buxton , H. T. , Furlong , E. T. , Esposito , K. and Stinson , B. 2010 . Pharmaceutical formulation facilities as sources of opioids and other pharmaceuticals to wastewater treatment plant effluents . Environmental Science and Technology , 44 : 4910 – 4916 .
   PubMed Web of Science ®Google Scholar
• Heberer , T. 2002 . Occurrence, fate, and removal of pharmaceutical residues in the aquatic environment: A review of recent research data . Toxicology Letters , 131 : 5 – 17 .
   PubMed Web of Science ®Google Scholar
• Holm , J. V. , Rügge , K. , Bjerg , P. L. and Christensen , T. H. 1995 . Occurrence and distribution of pharmaceutical organic compounds in the groundwater downgradient of a landfill (Grindsted, Denmark) . Environmental Science and Technology , 29 : 1415 – 1420 .
   PubMed Web of Science ®Google Scholar
• Godfrey , E. , Woessner , W. W. and Benotti , M. J. 2007 . Pharmaceuticals in on-site sewage effluent and ground water, Western Montana . Ground Water , 45 : 263 – 271 .
   PubMed Web of Science ®Google Scholar
• Kolpin , D. W. , Furlong , E. T. , Meyer , M. T. , Thurman , E. M. , Zaugg , S. D. , Barber , L. B. and Buxton , H. T. 2002 . Pharmaceuticals, hormones, and other organic wastewater contaminants in U.S. streams, 1999–2000: A national reconnaissance . Environmental Science and Technology , 36 : 1202 – 1211 .
   PubMed Web of Science ®Google Scholar
• Barnes , K. K. , Kolpin , D. W. , Furlong , E. T. , Zaugg , S. D. , Meyer , M. T. and Barber , L. B. 2008 . A national reconnaissance of pharmaceuticals and other organic wastewater contaminants in the United States: I) groundwater . Science of the Total Environment , 402 : 192 – 200 .
   PubMed Web of Science ®Google Scholar
• Fisher , P. M. J. and Scott , R. 2008 . Evaluating and controlling pharmaceutical emissions from dairy farms: A critical first step in developing a preventative management approach . Journal of Cleaner Production , 16 : 1437 – 1446 .
   Web of Science ®Google Scholar
• Yoon , Y. , Ryu , J. , Oh , J. , Byeong-Gyu , C. and Snyder , S. A. 2010 . Occurrence of endocrine disrupting compounds, pharmaceuticals, and personal care products in the Han River (Seoul, South Korea) . Science of the Total Environment , 408 : 636 – 643 .
   PubMed Web of Science ®Google Scholar
• Xu , W. , Zhang , G. , Zou , S. , Li , X. and Liu , Y. 2007 . Determination of selected antibiotics in the Victoria Harbour and the Pearl River, South China using high-performance liquid chromatography-electrospray ionization tandem mass spectrometry . Environmental Pollution , 145 : 672 – 679 .
   PubMed Web of Science ®Google Scholar
• Lin , A. Y. , Yu , T. and Lin , C. 2008 . Pharmaceutical contamination in residential, industrial, and agricultural waste streams: Risk to aqueous environments in Taiwan . Chemosphere , 74 : 131 – 141 .
   PubMed Web of Science ®Google Scholar
• Boyd , G. R. , Reemtsma , H. , Grimm , D. A. and Mitra , S. 2003 . Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada . The Science of the Total Environment , 311 : 135 – 149 .
   PubMed Web of Science ®Google Scholar
• Kasprzyk-Hordern , B. , Dinsdale , R. M. and Guwy , A. J. 2008 . The occurrence of pharmaceuticals, personal care products, endocrine disruptors and illicit drugs in surface water in South Wales, UK . Water Research , 42 : 3498 – 3518 .
   PubMed Web of Science ®Google Scholar
• Terzić , S. , Senta , I. , Ahel , M. , Gros , M. , Petrović , M. , Barcelo , D. , Müller , J. , Knepper , T. , Martí , I. , Ventura , F. , Jovančić , P. and Jabučar , D. 2008 . Occurrence and fate of emerging wastewater contaminants in Western Balkan Region . Science of the Total Environment , 399 : 66 – 77 .
   PubMed Web of Science ®Google Scholar
• Moldovan , Z. 2006 . Occurrences of pharmaceutical and personal care products as micropollutants in rivers from Romania . Chemosphere , 64 : 1808 – 1817 .
   PubMed Web of Science ®Google Scholar
• Pal , A. , Gin , K. Y. , Lin , A. Y. and Reinhard , M. 2010 . Impacts of emerging organic contaminants on freshwater resources: Review of recent occurrences, sources, fate and effects . Science of the Total Environment , 408 : 6062 – 6069 .
   PubMed Web of Science ®Google Scholar
• Daughton , C. G. 2007 . “ Chapter 1: Pharmaceuticals in the environment: Sources and their management ” . In Analysis, fate and removal of pharmaceuticals in the water cycle , Edited by: Petrović , M. and Barceló , D. 1–60 Boston , MA : Elsevier .
   Google Scholar
• Carballa , M. , Omil , F. and Lema , J. M. 2007 . Calculation methods to perform mass balances of micropollutants in sewage treatment plants. Application to pharmaceutical and personal care products (PPCPs) . Environmental Science and Technology , 41 : 884 – 890 .
   PubMed Web of Science ®Google Scholar
• Ternes , T. A. , Joss , A. and Siegrist , H. 2004 . Peer reviewed: Scrutinizing pharmaceuticals and personal care products in wastewater treatment . Environmental Science and Technology , 38 : 392A – 399A .
   PubMed Web of Science ®Google Scholar
• Petrović , M. , Gonzalez , S. and Barceló , D. 2003 . Analysis and removal of emerging contaminants in wastewater and drinking water . Trends in Analytical Chemistry , 22 : 685 – 696 .
   Web of Science ®Google Scholar
• Ternes , T. A. , Meisenheimer , M. , McDowell , D. , Sacher , F. , Brauch , H. , Haist-Gulde , B. , Preuss , G. , Wilme , U. and Zulei-Seibert , N. 2002 . Removal of pharmaceuticals during drinking water treatment . Environmental Science and Technology , 36 : 3855 – 3863 .
   PubMed Web of Science ®Google Scholar
• Miao , X. , Koenig , B. G. and Metcalfe , C. D. 2002 . Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography–electrospray ionization tandem mass spectrometry . Journal of Chromatography A , 952 : 139 – 147 .
   PubMed Web of Science ®Google Scholar
• Loftin , K. U.S. Geological Survey. Personal communication . April 21, 2010
   Google Scholar
• Hao , C. , Zhao , X. and Yang , P. 2007 . GC-MS and HPLC-MS analysis of bioactive pharmaceuticals and personal-care products in environmental matrices . Trends in Analytical Chemistry , 26 : 569 – 580 .
   Web of Science ®Google Scholar
• Miao , X. and Metcalfe , C. D. 2007 . “ Analysis of neutral and acidic pharmaceuticals by liquid chromatography mass spectrometry ” . In Analysis, fate and removal of pharmaceuticals in the water cycle , Edited by: Petrović , M. and Barceló , D. 133–157 Boston , MA : Elsevier .
   Google Scholar
• Esperanza , M. , Suidan , M. T. , Nishimura , F. , Wang , Z. , Sorial , G. A. , Zaffiro , A. , McCauley , P. , Brenner , R. and Sayles , G. 2004 . Determination of sex hormones and nonylphenol ethoxylates in the aqueous matrixes of two pilot-scale municipal wastewater treatment plants . Environmental Science and Technology , 38 : 3028 – 3035 .
   PubMed Web of Science ®Google Scholar
• Daughton , C. G. 2010 . “ Chapter 2: Pharmaceutical ingredients in drinking water: Overview of occurrence and significance of human exposure ” . In Contaminants of emerging concern in the environment: Ecological and human health considerations , Edited by: Halden , R. 9 – 57 . Washington , DC : American Chemical Society .
   Google Scholar
• Miège , C. , Choubert , J. M. , Ribeiro , L. , Eusèbe , M. and Coquery , M. 2009 . Fate of pharmaceuticals and personal care products in wastewater treatment plants: Conception of a database and first results . Environmental Pollution , 157 : 1721 – 1726 .
   PubMed Web of Science ®Google Scholar
• Lishman , L. , Smyth , S. A. , Sarafin , K. , Kleywegt , S. , Toito , J. , Peart , T. , Lee , B. , Servos , M. , Beland , M. and Seto , P. 2006 . Occurrence and reductions of pharmaceuticals and personal care products and estrogens by municipal wastewater treatment plants in Ontario, Canada . Science of the Total Environment , 367 : 544 – 558 .
   PubMed Web of Science ®Google Scholar
• Onesios , K. M. , Yu , J. T. and Bouwer , E. J. 2009 . Biodegradation and removal of pharmaceuticals and personal care products in treatment systems: A review . Biodegradation , 20 : 441 – 466 .
   PubMed Web of Science ®Google Scholar
• Matamoros , V. , García , J. and Bayona , J. M. 2008 . Organic micropollutant removal in a full-scale surface flow constructed wetland fed with secondary effluent . Water Research , 42 : 653 – 660 .
   PubMed Web of Science ®Google Scholar
• Sipma , J. , Osuna , B. , Collado , N. , Monclús , H. , Ferrero , G. , Comas , J. and Rodriguez-Roda , I. 2010 . Comparison of removal of pharmaceuticals in MBR and activated sludge systems . Desalination , 250 : 653 – 659 .
   Web of Science ®Google Scholar
• Reif , R. , Suárez , S. , Omil , F. and Lema , J. M. 2008 . Fate of pharmaceuticals and cosmetic ingredients during the operation of a MBR treating sewage . Desalination , 221 : 511 – 517 .
   Web of Science ®Google Scholar
• Carballa , M. , Omil , F. , Ternes , T. and Lema , J. M. 2007 . Fate of pharmaceutical and personal care products (PPCPs) during anaerobic digestion of sewage sludge . Water Research , 41 : 2139 – 2150 .
   PubMed Web of Science ®Google Scholar
• Carballa , M. , Manterola , G. , Larrea , L. , Ternes , T. , Omil , F. and Lema , J. M. 2007 . Influence of ozone pre-treatment on sludge anaerobic digestion: Removal of pharmaceutical and personal care products . Chemosphere , 67 : 1444 – 1452 .
   PubMed Web of Science ®Google Scholar
• Kim , I. and Tanaka , H. 2009 . Photodegradation characteristics of PPCPs in water with UV treatment . Environment International , 35 : 793 – 802 .
   PubMed Web of Science ®Google Scholar
• Pereira , V. J. , Weinberg , H. S. , Linden , K. G. and Singer , P. C. 2007 . UV degradation kinetics and modeling of pharmaceutical compounds in laboratory grade and surface water via direct and indirect photolysis at 254 nm . Environmental Science and Technology , 41 : 1682 – 1688 .
   PubMed Web of Science ®Google Scholar
• Snyder , S. A. , Adham , S. , Redding , A. M. , Cannon , F. S. , DeCarolis , J. , Oppenheimer , J. , Wert , E. C. and Yoon , Y. 2007 . Role of membranes and activated carbon in the removal of endocrine disruptors and pharmaceuticals . Desalination , 202 : 156 – 181 .
   Web of Science ®Google Scholar
• Guo , Y. C. and Krasner , S. W. 2009 . Occurrence of primidone, carbamazepine, caffeine, and precursors for N-nitrosodimethylamine in drinking water sources impacted by wastewater . Journal of the American Water Resources Association , 45 : 58 – 67 .
   Web of Science ®Google Scholar
• Westerhoff , P. , Yoon , Y. , Snyder , S. and Wert , E. 2005 . Fate of endocrine-disruptor, pharmaceutical, and personal care product chemicals during simulated drinking water treatment processes . Environmental Science and Technology , 39 : 6649 – 6663 .
   PubMed Web of Science ®Google Scholar
• Yoon , Y. , Westerhoff , P. , Snyder , S. A. and Wert , E. C. 2006 . Nanofiltration and ultrafiltration of endocrine disrupting compounds, pharmaceuticals and personal care products . Journal of Membrane Science , 270 : 88 – 100 .
   Web of Science ®Google Scholar
• Benotti , M. J. , Trenholm , R. A. , Vanderford , B. J. , Holady , J. C. , Stanford , B. D. and Snyder , S. A. 2009 . Pharmaceuticals and endocrine disrupting compounds in U.S. drinking water . Environmental Science and Technology , : 597 – 603 .
   PubMedGoogle Scholar
• Ternes , T. A. , Bonerz , M. , Herrmann , N. , Teiser , B. and Andersen , H. R. 2007 . Irrigation of treated wastewater in Braunschweig, Germany: An option to remove pharmaceuticals and musk fragrances . Chemosphere , 66 : 894 – 904 .
   PubMed Web of Science ®Google Scholar
• Drewes , J. E. , Heberer , T. , Rauch , T. and Reddersen , K. 2003 . Fate of pharmaceuticals during ground water recharge . Ground Water Monitoring & Remediation , 23 : 64 – 72 .
   Web of Science ®Google Scholar
• Fox , P. , Houston , S. , Westerhoff , P. , Drewes , J. E. , Nellor , M. , Yanko , W. , Baird , R. , Rincon , M. , Arnold , R. , Lansey , K. , Bassett , R. , Gerba , C. , Karpiscak , M. , Amy , G. and Reinhard , M. 2001 . Soil aquifer treatment for sustainable water reuse , Denver , CO : AWWA Research Foundation .
   Google Scholar
• Lapen , D. R. , Topp , E. , Metcalfe , C. D. , Li , H. , Edwards , M. , Gottschall , N. , Bolton , P. , Curnoe , W. , Payne , M. and Beck , A. 2008 . Pharmaceutical and personal care products in tile drainage following land application of municipal biosolids . Science of the Total Environment , 399 : 50 – 65 .
   PubMed Web of Science ®Google Scholar
• Topp , E. , Monteiro , S. C. , Beck , A. , Coelho , B. B. , Boxall , A. B. A. , Duenk , P. W. , Kleywegt , S. , Lapen , D. R. , Payne , M. , Sabourin , L. , Li , H. and Metcalfe , C. D. 2008 . Runoff of pharmaceuticals and personal care products following application of biosolids to an agricultural field . Science of the Total Environment , 396 : 52 – 59 .
   PubMed Web of Science ®Google Scholar
• Kinney , C. A. , Furlong , E. T. , Zaugg , S. D. , Burkhardt , M. R. , Werner , S. L. , Cahill , J. D. and Jorgensen , G. R. 2006 . Survey of organic wastewater contaminants in biosolids destined for land application . Environmental Science and Technology , 40 : 7207 – 7215 .
   PubMed Web of Science ®Google Scholar
• U.S. Environmental Protection Agency, Office of Water . 2000 . Biosolids technology fact sheet land application of biosolids EPA 832-F-00-064
   Google Scholar
• Jones-Lepp , T. and Stevens , R. 2007 . Pharmaceuticals and personal care products in biosolids/sewage sludge: The interface between analytical chemistry and regulation . Analytical and Bioanalytical Chemistry , 387 : 1173 – 1183 .
   PubMed Web of Science ®Google Scholar
• Kinney , C. A. , Furlong , E. T. , Werner , S. L. and Cahill , J. D. 2006 . Presence and distribution of wastewater-derived pharmaceuticals in soil irrigated with reclaimed water . Environmental Toxicology and Chemistry , 25 : 317 – 326 .
   PubMed Web of Science ®Google Scholar
• Ferrer , I. and Furlong , E. T. 2002 . Accelerated solvent extraction followed by on-line solid-phase extraction coupled to ion trap LC/MS/MS for analysis of benzalkonium chlorides in sediment samples . Analytical Chemistry , 74 : 1275 – 1280 .
   PubMed Web of Science ®Google Scholar
• Burkhardt , M. R. , ReVello , R. C. , Smith , S. G. and Zaugg , S. D. 2005 . Pressurized liquid extraction using water/isopropanol coupled with solid-phase extraction cleanup for industrial and anthropogenic waste-indicator compounds in sediment . Analytica Chimica Acta , 534 : 89 – 100 .
   Web of Science ®Google Scholar
• Guler , Y. and Ford , A. T. 2010 . Anti-depressants make amphipods see the light . Aquatic Toxicology , 99 : 397 – 404 .
   PubMed Web of Science ®Google Scholar
• Fent , K. , Weston , A. A. and Caminada , D. 2006 . Ecotoxicology of human pharmaceuticals . Aquatic Toxicology , 76 : 122 – 159 .
   PubMed Web of Science ®Google Scholar
• Ericson , H. , Thorsén , G. and Kumblad , L. 2010 . Physiological effects of diclofenac, ibuprofen and propranolol on Baltic Sea blue mussels . Aquatic Toxicology , 99 : 223 – 231 .
   PubMed Web of Science ®Google Scholar
• Saaristo , M. , Craft , J. A. , Lehtonen , K. K. and Lindström , K. 2010 . An endocrine disrupting chemical changes courtship and parental care in the sand goby . Aquatic Toxicology , 97 : 285 – 292 .
   PubMed Web of Science ®Google Scholar
• Lindström , K. , St. Mary , C. M. and Pampoulie , C. 2006 . Sexual selection for male parental care in the sand goby, Pomatoschistus minutus . Behavioral Ecology and Sociobiology , 60 : 46 – 51 .
   Web of Science ®Google Scholar
• Forsgren , E. 1992 . Predation risk affects mate choice in a gobiid fish . The American Naturalist , 140 : 1041 – 1049 .
   Web of Science ®Google Scholar
• Fair , P. A. , Lee , H. , Adams , J. , Darling , C. , Pacepavicius , G. , Alaee , M. , Bossart , G. D. , Henry , N. and Muir , D. 2009 . Occurrence of triclosan in plasma of wild Atlantic bottlenose dolphins (tursiops truncatus) and in their environment . Environmental Pollution , 157 : 2248 – 2254 .
   PubMed Web of Science ®Google Scholar
• Wilson , B. A. , Smith , V. H. , Denoyelles , F. and Larive , C. K. 2003 . Effects of three pharmaceutical and personal care products on natural freshwater algal assemblages . Environmental Science and Technology , 37 : 1713 – 1719 .
   PubMed Web of Science ®Google Scholar
• Giudice , B. D. and Young , T. M. 2010 . The antimicrobial triclocarban stimulates embryo production in the freshwater mudsnail Potamopyrgus Antipodarum . Environmental Toxicology and Chemistry , 29 : 966 – 970 .
   PubMed Web of Science ®Google Scholar
• Halden , R. U. and Paull , D. H. 2005 . Co-occurrence of triclocarban and triclosan in U.S. water resources . Environmental Science and Technology , 39 : 1420 – 1426 .
   PubMed Web of Science ®Google Scholar
• Chen , J. , Ahn , K. C. , Gee , N. A. , Ahmed , M. I. , Duleba , A. J. , Zhao , L. , Gee , S. J. , Hammock , B. D. and Lasley , B. L. 2008 . Triclocarban enhances testosterone action: a new type of endocrine disruptor? . Endocrinology , 149 : 1173 – 1179 .
   PubMed Web of Science ®Google Scholar
• Matthiessen , P. 2008 . An assessment of endocrine disruption in mollusks and the potential for developing internationally standardized mollusk life cycle test guidelines . Integrated Environmental Assessment and Management , 4 : 274 – 284 .
   PubMedGoogle Scholar
• Duft , M. , Schulte-Oehlmann , U. , Weltje , L. , Tillmann , M. and Oehlmann , J. 2003 . Stimulated embryo production as a parameter of estrogenic exposure via sediments in the freshwater mudsnail Potamopyrgus antipodarum . Aquatic Toxicology , 64 : 437 – 449 .
   PubMed Web of Science ®Google Scholar
• Oggier , D. M. , Weisbrod , C. J. , Stoller , A. M. , Zenker , A. K. and Fent , K. 2010 . Effects of diazepam on gene expression and link to physiological effects in different life stages in zebrafish Danio rerio . Environmental Science and Technology , 44 : 7685 – 7691 .
   PubMed Web of Science ®Google Scholar
• Kallio , J. , Lahti , M. , Oikari , A. and Kronberg , L. 2010 . Metabolites of the aquatic pollutant diclofenac in fish bile . Environmental Science and Technology , 44 : 7213 – 7219 .
   PubMed Web of Science ®Google Scholar
• Brooks , B. , Chambliss , C. K. , Stanley , J. K. , Ramirez , A. , Banks , K. E. , Johnson , R. D. and Lewis , R. J. 2005 . Determination of select antidepressants in fish from an effluent-dominated stream . Environmental Toxicology and Chemistry , 24 : 464 – 469 .
   PubMed Web of Science ®Google Scholar
• Daughton , C. G. 2003 . Cradle-to-cradle stewardship of drugs for minimizing their environmental disposition while promoting human health. II. Drug disposal, waste reduction, and future directions . Environmental Health Perspectives , 111 : 775 – 785 .
   PubMed Web of Science ®Google Scholar
• US Department of Justice, Office of Public Affairs . 2010 . DEA heads first-ever nationwide prescription drug take-back day August 19, Press release
   Google Scholar
• Benedict , M. U.S. Environmental Protection Agency. Personal communication . November 12, 2010
   Google Scholar
• Carpenter , T. R. U.S. Environmental Protection Agency. Personal communication . May 18, 2010
   Google Scholar
• U.S. Environmental Protection Agency . 2008 . Drinking water contaminant candidate list 3—draft; notice EPA-HQ-OW-2007-1189 FRL-8529-7
   Google Scholar
• U.S. Environmental Protection Agency, Office of Water . 2009 . Final contaminant candidate list 3, chemicals: Classification of the PCCL to the CCL EPA 815-R-09-008
   Google Scholar
• Rudzinski , S. U.S. Environmental Protection Agency. Personal communication . May 10, 2010
   Google Scholar
• U.S. Environmental Protection Agency, Office of Water . 2010 . Treating contaminants of emerging concern: A literature review database EPA-820-R-10-002, EPA
   Google Scholar
• Smith , M. T. U.S. Environmental Protection Agency. Personal communication . July 1, 2010
   Google Scholar
• U.S. Environmental Protection Agency . 2008 . 40 CFR Part 260, 261, 264, et al. Amendment to the universal waste rule: Addition of pharmaceuticals; proposed rule EPA-HQ-RCRA-2007-0932; FRL-8746-2
   Google Scholar
• Kolpin , D. W. U.S. Geological Survey. Personal communication . March 22, 2010
   Google Scholar