Chemotherapeutic potential of quercetin on human bladder cancer cells

References

• Ploeg, M.; Aben, K.K.; Kiemeney, L.A. The present and future burden of urinary bladder cancer in the world. World. J. Urol. 2009, 27(3), 289–293.
   PubMed Web of Science ®Google Scholar
• Oosterlinck, W.; Solsona, E.; van der Meijden, A.P.; Sylvester, R.; Böhle, A.; Rintala, E.; Lobel, B. European Association of Urology. EAU guidelines on diagnosis and treatment of upper urinary tract transitional cell carcinoma. Eur. Urol. 2004, 46(2), 147−154.
   PubMed Web of Science ®Google Scholar
• Sylvester, R.J.; van der Meijden, A.P.; Oosterlinck, W.; Witjes, J.A.; Bouffioux, C.; Denis L; Newling DW; Kurth, K. Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials. Eur. Urol. 2006, 49(3), 466−475.
   PubMed Web of Science ®Google Scholar
• Rockenbach, L.; Bavaresco, L.; Fernandes Farias, P.; Cappellari, A.R.; Barrios, C.H.; Bueno Morrone, F.; Oliveira Battastini, A.M. Alterations in the extracellular catabolism of nucleotides are involved in the antiproliferative effect of quercetin in human bladder cancer T24 cells. Urol. Oncol. 2013, 31(7), 1204−1211.
   PubMed Web of Science ®Google Scholar
• Boots, A.W.; Haenen, G.R.; Bast, A. Health effects of quercetin: from antioxidant to nutraceutical. Eur. J. Pharmacol. 2008, 585(2−3), 325−337.
   PubMed Web of Science ®Google Scholar
• Dajas, F. Life or death: neuroprotective and anticancer effects of quercetin. J. Ethnopharmacol. 2012, 143(2), 383−396.
   PubMed Web of Science ®Google Scholar
• Russo, M.; Spagnuolo, C.; Tedesco, I.; Bilotto, S.; Russo, G.L. The flavonoid quercetin in disease prevention and therapy: facts and fancies. Biochem. Pharmacol. 2012, 83(1), 6−15.
   PubMed Web of Science ®Google Scholar
• D'Andrea, G. Quercetin A flavonol with multifaceted therapeutic applications? Fitoterapia. 2015, 106, 256−271.
   Google Scholar
• Oršolić, N. A review of propolis antitumor action in vivo and in vitro. JAAS. 2010, 2, 1−20.
   Google Scholar
• Ruiz, M.J.; Fernández, M.; Picó Y; Mañes, J.; Asensi, M.; Carda, C.; Asensio, G.; Estrela, J.M. Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic. J. Agric. Food. Chem. 2009, 57(8), 3180−3186.
   PubMed Web of Science ®Google Scholar
• Khan, S.I.; Zhao, J.; Khan, I.A.; Walker, L.A.; Dasmahapatra, A.K. Potential utility of natural products as regulators of breast cancer-associated aromatase promoters. Reprod. Biol. Endocrinol. 2011, 9, 91.
   PubMed Web of Science ®Google Scholar
• Kim, H.J.; Kim, S.K.; Kim, B.S.; Lee, S.H.; Park, Y.S.; Park, B.K.; Kim, S.J.; Kim, J.; Choi, C.; Kim, J.S.; Cho, S.D.; Jung, J.W.; Roh, K.H.; Kang, K.S.; Jung, J.Y. Apoptotic effect of quercetin on HT-29 colon cancer cells via the AMPK signaling pathway. J. Agric. Food Chem. 2010, 58(15), 8643−8650.
   PubMed Web of Science ®Google Scholar
• Wang, K.; Liu, R.; Li, J.; Mao, J.; Lei, Y.; Wu, J.; Zeng, J.; Zhang, T.; Wu, H.; Chen, L.; Huang, C.; Wei, Y. Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling. Autophagy. 2011, 7(9), 966−978.
   PubMed Web of Science ®Google Scholar
• Josipović.P.; Oršolić, N. Cytotoxicity of polyphenolic/flavonoid compounds in a leukaemia cell culture. Arh. Hig. Rada Toksikol. 2008, 59(4), 299−308.
   PubMed Web of Science ®Google Scholar
• Long, Q.; Xiel, Y.; Huang, Y.; Wu, Q.; Zhang, H.; Xiong, S.; Liu, Y.; Chen, L.; Wei, Y.; Zhao, X.; Gong, C. Induction of apoptosis and inhibition of angiogenesis by PEGylated liposomal quercetin in both cisplatin-sensitive and cisplatin-resistant ovarian cancers. J. Biomed. Nanotechnol. 2013, 9(6), 965−975.
   PubMed Web of Science ®Google Scholar
• Oršolić, N.; Štajcar, D.; Bašić, I. Propolis and its flavonoid compounds cause cytotoxicity on human urinary bladder transitional cell carcinoma in primary culture. Period. Biol. 2009, 111(1), 113−121.
   Web of Science ®Google Scholar
• Vidya Priyadarsini, R.; Senthil Murugan, R.; Maitreyi, S.; Ramalingam, K.; Karunagaran, D.; Nagini, S. The flavonoid quercetin induces cell cycle arrest and mitochondria-mediated apoptosis in human cervical cancer (HeLa) cells through p53 induction and NF-κB inhibition. Eur. J. Pharmacol. 2010, 649(1−3), 84−91.
   PubMed Web of Science ®Google Scholar
• Beniston, R.G.; Campo, M.S. Quercetin elevates p27(Kip1) and arrests both primary and HPV16 E6/E7 transformed human keratinocytes in G1. Oncogene. 2003, 22(35), 5504−5514.
   PubMed Web of Science ®Google Scholar
• Singh, N.P.; McCoy, M.T.; Tice, R.R.; Schneider, E.L. A simple technique for quantitation of low levels of DNA damage in individual cells. Exp. Cell Res. 1988, 175(1), 184−191.
   PubMed Web of Science ®Google Scholar
• Garaj-Vrhovac, V.; Gajski, G. Evaluation of the cytogenetic status of human lymphocytes after exposure to a high concentration of bee venom in vitro. Arh. Hig. Rada Toksikol. 2009, 60(1), 27−34.
   PubMed Web of Science ®Google Scholar
• Reljić, A.; Tomas, D.; Gabelić, T.; Zarubica, J.; Bulimbašić, S.; Fazlić, H.; Čupić, H.; Krušlin, B. Stromal reaction in synchrounous in situ and invasive urothelial carcinoma of the bladder. Acta Clin. Croat. 2006, 45, 173−179.
   Google Scholar
• Yao, R.; Davidson, D.D.; Lopez-Beltran, A.; MacLennan, G.T.; Montironi, R.; Cheng, L. The S100 proteins for screening and prognostic grading of bladder cancer. Histol. Histopathol. 2007, 22(9), 1025−1032.
   PubMed Web of Science ®Google Scholar
• Liu, RH. Health-promoting components of fruits and vegetables in the diet. Adv. Nutr. 2013, 4(3), 384S−392S.
   PubMed Web of Science ®Google Scholar
• Jakubowicz-Gil, J.; Pawlikowska-Pawlega, B.; Piersiak, T.; Pawelec, J.; Gawron, A. Quercetin suppresses heat shock-induced nuclear translocation of Hsp72. Folia Histochem. Cytobiol. 2005, 43(3), 123−128.
   PubMed Web of Science ®Google Scholar
• Oršolić, N.; Car, N. Quercetin and hyperthermia modulate cisplatin-induced DNA damage in tumor and normal tissues in vivo. Tumour Biol 2014, 35(7), 6445−6454.
   PubMed Web of Science ®Google Scholar
• Gasión, J.P.; Cruz, J.F. Improving Efficacy of Intravesical Chemotherapy. Eur. Urol. 2006, 50(2), 225–234.
   PubMed Web of Science ®Google Scholar
• Azqueta, A.; Collins, A.R. The essential comet assay: a comprehensive guide to measuring DNA damage and repair. Arch. Toxicol. 2013, 87(6), 949−968.
   PubMed Web of Science ®Google Scholar
• Russo, G.L.; Russo, M.; Spagnuolo, C.; Tedesco, I.; Bilotto, S.; Iannitti, R.; Palumbo, R. Quercetin: a pleiotropic kinase inhibitor against cancer. Cancer Treat. Res. 2014, 159, 185−205.
   PubMedGoogle Scholar
• Yoshimura, R.; Matsuyama, M.; Tsuchida, K.; Kawahito, Y.; Sano, H.; Nakatani, T. Expression of lipoxygenase in human bladder carcinoma and growth inhibition by its inhibitors. J. Urol. 2003, 170(5), 1994−1999.
   PubMed Web of Science ®Google Scholar
• Mohseni, H.; Zaslau, S.; McFadden, D.; Riggs, D.R.; Jackson, B.J.; Kandzari, S. COX-2 inhibition demonstrates potent anti-proliferative effects on bladder cancer in vitro. J. Surg. Res. 2004, 119(2), 138−142.
   PubMed Web of Science ®Google Scholar
• Knežević, A.H.; Dikić, D.; Lisičić, D.; Kopjar, N.; Oršolić, N.; Karabeg, S; Benković, V. Synergistic effects of irinotecan and flavonoids on Ehrlich ascites tumour-bearing mice. Basic Clin. Pharmacol. Toxicol. 2011, 109(5), 343−349.
   PubMed Web of Science ®Google Scholar
• Oršolić, N.; Šver, L.; Terzić, S.; Tadić, Z.; Bašić, I. Inhibitory effect of water-soluble derivative of propolis and its polyphenolic compounds on tumor growth and metastasizing ability: a possible mode of antitumor action. Nutr. Cancer. 2003, 47(2), 156−163.
   PubMed Web of Science ®Google Scholar
• Kamat, A.M.; Lamm, D.L. Chemoprevention of bladder cancer. Urol. Clin. North. Am. 2002, 29(1), 157−168.
   PubMed Web of Science ®Google Scholar
• Koya, M.P.; Simon, M.A.; Soloway, M.S. Complications of intravesical therapy for urothelial cancer of the bladder. J. Urol. 2006, 175(6), 2004−2010.
   PubMed Web of Science ®Google Scholar
• Van der Meijden, A.P.; Sylvester, R.J.; Oosterlinck, W.; Hoeltl, W.; Bono, A.V.; EORTC Genito-Urinary Tract Cancer Group Maintenance Bacillus Calmette-Guerin for Ta T1 bladder tumors is not associated with increased toxicity: results from a European Organisation for Research and Treatment of Cancer Genito-Urinary Group Phase III Trial. Eur. Urol. 2003, 44(4), 429−434.
   PubMed Web of Science ®Google Scholar