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Original Articles

Environmental Contaminant Exposures and Preterm Birth: A Comprehensive Review

, &
Pages 69-113 | Published online: 17 May 2013

REFERENCES

  • Adibi , J. J. , Hauser , R. , Williams , P. L. , Whyatt , R. M. , Calafat , A. M. , Nelson , H. , Herrick , R. and Swan , S. H. 2009 . Maternal urinary metabolites of di- (2-ethylhexyl) phthalate in relation to the timing of labor in a US multicenter pregnancy cohort study . Am. J. Epidemiol , 169 : 1015 – 1024 .
  • Agency for Toxic Substances and Disease Registry . 1995 . Toxicological profile for polycyclic aromatic hydrocarbons (PAHs) , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 1997a . Toxicological profile for tetrachloroethylene , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 1997b . Toxicological profile for trichloroethylene , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 1998 . Toxicological profile for chlorinated dibenzo-p-dioxins (CDDs) , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2000 . Toxicological profile for polychlorinated biphenyls (PCBs) , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2002a . Toxicological profile for hexachlorobenzene , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2002b . Toxicological profile for aldrin/dieldrin , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2002c . Toxicological profile for DDT, DDE, and DDD , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2003 . Toxicological profile for atrazine , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2005 . Toxicological profile for alpha-, beta-, gamma-, and delta-hexachlorocyclohexane , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2007a . Toxicological profile for heptachlor and heptachor epoxide , Atlanta , GA: U.S : Department of Health and Human Services .
  • Agency for Toxic Substances and Disease Registry . 2007b . Toxicological profile for lead (Update) , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2008 . Toxicological profile for cadmium , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Agency for Toxic Substances and Disease Registry . 2009 . Toxicological profile for perfluoroalkyls (draft for public comment) , Atlanta , GA : U.S. Department of Health and Human Services, Public Health Service .
  • Aggazzotti , G. , Righi , E. , Fantuzzi , G. , Biasotti , B. , Ravera , G. , Kanitz , S. , Barbone , F. , Sansebastiano , G. , Battaglia , M. A. , Leoni , V. , Fabiani , L. , Triassi , M. and Sciacca , S. 2004 . Chlorination by-products (CBPs) in drinking water and adverse pregnancy outcomes in Italy . J. Water Health , 2 : 233 – 247 .
  • Ahmad , S. A. , Sayed , M. H. , Barua , S. , Khan , M. H. , Faruquee , M. H. , Jalil , A. , Hadi , S. A. and Talukder , H. K. 2001 . Arsenic in drinking water and pregnancy outcomes . Environ. Health Perspect , 109 : 629 – 631 .
  • Andrews , K. W. , Savitz , D. A. and Hertz-Picciotto , I. 1994 . Prenatal lead exposure in relation to gestational age and birth weight: A review of epidemiologic studies . Am. J. Ind. Med , 26 : 13 – 32 .
  • Apelberg , B. J. , Witter , F. R. , Herbstman , J. B. , Calafat , A. M. , Halden , R. U. , Needham , L. L. and Goldman , L. R. 2007 . Cord serum concentrations of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in relation to weight and size at birth . Environ. Health Perspect , 115 : 1670 – 1676 .
  • Arbuckle , T. E. , Kubwabo , C. , Walker , M. , Davis , K. , Lalonde , K. , Kosarac , I. , Wen , S. W. and Arnold , D. L. 2012 . Umbilical cord blood levels of perfluoroalkyl acids and polybrominated flame retardants . Int. J. Hyg. Environ. Health , 216: 184–194.
  • Aschengrau , A. , Weinberg , J. , Rogers , S. , Gallagher , L. , Winter , M. , Vieira , V. , Webster , T. and Ozonoff , D. 2008 . Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of adverse birth outcomes . Environ. Health Perspect , 116 : 814 – 820 .
  • Ashton , D. M. , Lawrence , H. C. , Adams , N. L. and Fleischman , A. R. 2009 . Surgeon General's Conference on the prevention of preterm birth . Obstet. Gynecol , 113 : 925 – 930 . 3rd3rd
  • Bartell , S. M. , Calafat , A. M. , Lyu , C. , Kato , K. , Ryan , P. B. and Steenland , K. 2010 . Rate of decline in serum PFOA concentrations after granular activated carbon filtration at two public water systems in Ohio and West Virginia . Environ. Health Perspect , 118 : 222 – 228 .
  • Behrman , R. E. and Butler , A. S. , eds. 2007 . Preterm birth: Causes, consequences, and prevention , Washington , DC : National Academies Press .
  • Bergonzi , R. , De Palma , G. , Specchia , C. , Dinolfo , M. , Tomasi , C. , Frusca , T. and Apostoli , P. 2011 . Persistent organochlorine compounds in fetal and maternal tissues: Evaluation of their potential influence on several indicators of fetal growth and health . Sci. Total Environ , 409 : 2888 – 2893 .
  • Berkowitz , G. S. , Lapinski , R. H. and Wolff , M. S. 1996 . The role of DDE and polychlorinated biphenyl levels in preterm birth . Arch. Environ. Contam. Toxicol , 30 : 139 – 141 .
  • Bloom , M. S. , Buck Louis , G. M. , Schisterman , E. F. , Liu , A. and Kostyniak , P. J. 2007 . Maternal serum polychlorinated biphenyl concentrations across critical windows of human development . Environ. Health Perspect , 115 : 1320 – 1324 .
  • Bonzini , M. , Carugno , M. , Grillo , P. , Mensi , C. , Bertazzi , P. A. and Pesatori , A. C. 2010 . Impact of ambient air pollution on birth outcomes: Systematic review of the current evidences . Med. Lav , 101 : 341 – 363 .
  • Bove , F. J. , Fulcomer , M. C. , Klotz , J. B. , Esmart , J. , Dufficy , E. M. and Savrin , J. E. 1995 . Public drinking water contamination and birth outcomes . Am. J. Epidemiol , 141 : 850 – 862 .
  • Boyle , E. M. , Poulsen , G. , Field , D. J. , Kurinczuk , J. J. , Wolke , D. , Alfirevic , Z. and Quigley , M. A. 2012 . Effects of gestational age at birth on health outcomes at 3 and 5 years of age: Population based cohort study . Br. Med. J , 344 : e896
  • Calafat , A. M. , Ye , X. , Wong , L. Y. , Reidy , J. A. and Needham , L. L. 2008 . Exposure of the U.S. population to bisphenol A and 4-tertiary-octylphenol: 2003–2004 . Environ. Health Perspect , 116 : 39 – 44 .
  • Cantonwine , D. , Hu , H. , Sanchez , B. N. , Lamadrid-Figueroa , H. , Smith , D. , Ettinger , A. S. , Mercado-Garcia , A. , Hernandez-Avila , M. , Wright , R. O. and Tellez-Rojo , M. M. 2010a . Critical windows of fetal lead exposure: Adverse impacts on length of gestation and risk of premature delivery . J. Occup. Environ. Med , 52 : 1106 – 1111 .
  • Cantonwine , D. , Meeker , J. D. , Hu , H. , Sanchez , B. N. , Lamadrid-Figueroa , H. , Mercado-Garcia , A. , Fortenberry , G. Z. , Calafat , A. M. and Tellez-Rojo , M. M. 2010b . Bisphenol a exposure in Mexico City and risk of prematurity: A pilot nested case control study . Environ. Health , 9 : 62
  • Centers for Disease Control and Prevention . 2009 . Fourth national report on human exposure to environmental chemicals www.cdc.gov/exposurereport/
  • Chen , M. H. , Ha , E. H. , Wen , T. W. , Su , Y. N. , Lien , G. W. , Chen , C. Y. , Chen , P. C. and Hsieh , W. S. 2012 . Perfluorinated compounds in umbilical cord blood and adverse birth outcomes . PLoS One , 7 : e42474
  • Choi , H. , Rauh , V. , Garfinkel , R. , Tu , Y. and Perera , F. P. 2008 . Prenatal exposure to airborne polycyclic aromatic hydrocarbons and risk of intrauterine growth restriction . Environ. Health Perspect , 116 : 658 – 665 .
  • Clark , S. L. , Miller , D. D. , Belfort , M. A. , Dildy , G. A. , Frye , D. K. and Meyers , J. A. 2009 . Neonatal and maternal outcomes associated with elective term delivery . Am. J. Obstet. Gynecol , 200 : e151 – 154 . 156
  • Cole , F. S. , Alleyne , C. , Barks , J. D. , Boyle , R. J. , Carroll , J. L. , Dokken , D. , Edwards , W. H. , Georgieff , M. , Gregory , K. , Johnston , M. V. , Kramer , M. , Mitchell , C. , Neu , J. , Pursley , D. M. , Robinson , W. M. and Rowitch , D. H. 2011 . NIH Consensus Development Conference statement: Inhaled nitric-oxide therapy for premature infants . Pediatrics , 127 : 363 – 369 .
  • Costet , N. , Garlantezec , R. , Monfort , C. , Rouget , F. , Gagniere , B. , Chevrier , C. and Cordier , S. 2012 . Environmental and urinary markers of prenatal exposure to drinking water disinfection by-products, fetal growth, and duration of gestation in the PELAGIE birth cohort (Brittany, France, 2002–2006) . Am. J. Epidemiol , 175 : 263 – 275 .
  • de Rosa , C. T. , El-Masri , H. A. , Pohl , H. , Cibulas , W. and Mumtaz , M. M. 2004 . Implications of chemical mixtures in public health practice . J. Toxicol. Environ. Health B , 7 : 339 – 350 .
  • Dodds , L. , King , W. , Woolcott , C. and Pole , J. 1999 . Trihalomethanes in public water supplies and adverse birth outcomes . Epidemiology , 10 : 233 – 237 .
  • Eskenazi , B. , Mocarelli , P. , Warner , M. , Chee , W. Y. , Gerthoux , P. M. , Samuels , S. , Needham , L. L. and Patterson , D. G. Jr. 2003 . Maternal serum dioxin levels and birth outcomes in women of Seveso, Italy . Environ. Health Perspect , 111 : 947 – 953 .
  • Eskenazi , B. , Harley , K. , Bradman , A. , Weltzien , E. , Jewell , N. P. , Barr , D. B. , Furlong , C. E. and Holland , N. T. 2004 . Association of in utero organophosphate pesticide exposure and fetal growth and length of gestation in an agricultural population . Environ. Health Perspect , 112 : 1116 – 1124 .
  • Fagher , U. , Laudanski , T. , Schutz , A. , Sipowicz , M. and Akerlund , M. 1993 . The relationship between cadmium and lead burdens and preterm labor . Int. J. Gynaecol. Obstet , 40 : 109 – 114 .
  • Falcon , M. , Vinas , P. and Luna , A. 2003 . Placental lead and outcome of pregnancy . Toxicology , 185 : 59 – 66 .
  • Farhang , L. , Weintraub , J. M. , Petreas , M. , Eskenazi , B. and Bhatia , R. 2005 . Association of DDT and DDE with birth weight and length of gestation in the Child Health and Development Studies, 1959–1967 . Am. J. Epidemiol , 162 : 717 – 725 .
  • Fei , C. , McLaughlin , J. K. , Tarone , R. E. and Olsen , J. 2007 . Perfluorinated chemicals and fetal growth: A study within the Danish National Birth Cohort . Environ. Health Perspect , 115 : 1677 – 1682 .
  • Fenster , L. , Eskenazi , B. , Anderson , M. , Bradman , A. , Harley , K. , Hernandez , H. , Hubbard , A. and Barr , D. B. 2006 . Association of in utero organochlorine pesticide exposure and fetal growth and length of gestation in an agricultural population . Environ. Health Perspect , 114 : 597 – 602 .
  • Forand , S. P. , Lewis-Michl , E. L. and Gomez , M. I. 2011 . Maternal exposure to tetrachloroethylene and trichloroethylene through soil vapor intrusion and adverse birth outcomes in New York State . Environ. Health Perspect , 120 : 616 – 621 .
  • Gallagher , M. D. , Nuckols , J. R. , Stallones , L. and Savitz , D. A. 1998 . Exposure to trihalomethanes and adverse pregnancy outcomes . Epidemiology , 9 : 484 – 489 .
  • Glinianaia , S. V. , Rankin , J. , Bell , R. , Pless-Mulloli , T. and Howel , D. 2004 . Particulate air pollution and fetal health: A systematic review of the epidemiologic evidence . Epidemiology , 15 : 36 – 45 .
  • Glynn , A. , Larsdotter , M. , Aune , M. , Darnerud , P.O. , Bjerselius , R. and Bergman , A. 2011 . Changes in serum concentrations of polychlorinated biphenyls (PCBs), hydroxylated PCB metabolites and pentachlorophenol during pregnancy . Chemosphere , 83 : 144 – 151 .
  • Govarts , E. , Nieuwenhuijsen , M. , Schoeters , G. , Ballester , F. , Bloemen , K. , de Boer , M. , Chevrier , C. , Eggesbo , M. , Guxens , M. , Kramer , U. , Legler , J. , Martinez , D. , Palkovicova , L. , Patelarou , E. , Ranft , U. , Rautio , A. , Petersen , M. S. , Slama , R. , Stigum , H. , Toft , G. , Trnovec , T. , Vandentorren , S. , Weihe , P. , Kuperus , N. W. , Wilhelm , M. , Wittsiepe , J. , Bonde , J. P. and Obelix , E. 2012 . Birth weight and prenatal exposure to polychlorinated biphenyls (PCBs) and dichlorodiphenyldichloroethylene (DDE): A meta-analysis within 12 European birth cohorts . Environ. Health Perspect , 120 : 162 – 170 .
  • Grellier , J. , Bennett , J. , Patelarou , E. , Smith , R. B. , Toledano , M. B. , Rushton , L. , Briggs , D. J. and Nieuwenhuijsen , M. J. 2010 . Exposure to disinfection by-products, fetal growth, and prematurity: A systematic review and meta-analysis . Epidemiology , 21 : 300 – 313 .
  • Guellec , I. , Lapillonne , A. , Renolleau , S. , Charlaluk , M. L. , Roze , J. C. , Marret , S. , Vieux , R. , Monique , K. and Ancel , P. Y. 2011 . Neurologic outcomes at school age in very preterm infants born with severe or mild growth restriction . Pediatrics , 127 : e883 – e891 .
  • Guo , Y. , Huo , X. , Wu , K. , Liu , J. , Zhang , Y. and Xu , X. 2012 . Carcinogenic polycyclic aromatic hydrocarbons in umbilical cord blood of human neonates from Guiyu, China . Sci. Total Environ , 427–428 : 35 – 40 .
  • Hamel , A. , Mergler , D. , Takser , L. , Simoneau , L. and Lafond , J. 2003 . Effects of low concentrations of organochlorine compounds in women on calcium transfer in human placental syncytiotrophoblast . Toxicol. Sci , 76 : 182 – 189 .
  • Hamm , M. P. , Cherry , N. M. , Chan , E. , Martin , J. W. and Burstyn , I. 2010 . Maternal exposure to perfluorinated acids and fetal growth . J. Expos. Sci. Environ. Epidemiol , 20 : 589 – 597 .
  • Hinckley , A. F. , Bachand , A. M. , Nuckols , J. R. and Reif , J. S. 2005 . Identifying public water facilities with low spatial variability of disinfection by-products for epidemiological investigations . Occup. Environ. Med , 62 : 494 – 499 .
  • Hoffman , C. S. , Mendola , P. , Savitz , D. A. , Herring , A. H. , Loomis , D. , Hartmann , K. E. , Singer , P. C. , Weinberg , H. S. and Olshan , A. F. 2008 . Drinking water disinfection by-product exposure and duration of gestation . Epidemiology , 19 : 738 – 746 .
  • Horton , B. J. , Luben , T. J. , Herring , A. H. , Savitz , D. A. , Singer , P. C. , Weinberg , H. S. and Hartmann , K. E. 2011 . The effect of water disinfection by-products on pregnancy outcomes in two southeastern US communities . J. Occup. Environ. Med , 53 : 1172 – 1178 .
  • Jaakkola , J. J. , Magnus , P. , Skrondal , A. , Hwang , B. F. , Becher , G. and Dybing , E. 2001 . Foetal growth and duration of gestation relative to water chlorination . Occup. Environ. Med , 58 : 437 – 442 .
  • Jelliffe-Pawlowski , L. L. , Miles , S. Q. , Courtney , J. G. , Materna , B. and Charlton , V. 2006 . Effect of magnitude and timing of maternal pregnancy blood lead (Pb) levels on birth outcomes . J. Perinatol , 26 : 154 – 162 .
  • Kallen , B. A. and Robert , E. 2000 . Drinking water chlorination and delivery outcome—A registry-based study in Sweden . Reprod. Toxicol , 14 : 303 – 309 .
  • Kanitz , S. , Franco , Y. , Patrone , V. , Caltabellotta , M. , Raffo , E. , Riggi , C. , Timitilli , D. and Ravera , G. 1996 . Association between drinking water disinfection and somatic parameters at birth . Environ. Health Perspect , 104 : 516 – 520 .
  • Kim , H. , Haltmeier , P. , Klotz , J. B. and Weisel , C. P. 1999 . Evaluation of biomarkers of environmental exposures: Urinary haloacetic acids associated with ingestion of chlorinated drinking water . Environ. Res , 80 : 187 – 195 .
  • Klebanoff , M. A. and Shiono , P. H. 1995 . Top down, bottom up and inside out: Reflections on preterm birth . Paediatr. Perinat. Epidemiol , 9 : 125 – 129 .
  • Kochanek , K. D. , Kirmeyer , S. E. , Martin , J. A. , Strobino , D. M. and Guyer , B. 2012 . Annual summary of vital statistics: 2009 . Pediatrics , 129 : 338 – 348 .
  • Kramer , M. D. , Lynch , C. F. , Isacson , P. and Hanson , J. W. 1992 . The association of waterborne chloroform with intrauterine growth retardation . Epidemiology , 3 : 407 – 413 .
  • Landgren , O. 1996 . Environmental pollution and delivery outcome in southern Sweden: A study with central registries . Acta Paediatr , 85 : 1361 – 1364 .
  • Le , T. N. and Johansson , A. 2001 . Impact of chemical warfare with Agent Orange on women's reproductive lives in Vietnam: A pilot study . Reprod. Health Matters , 9 : 156 – 164 .
  • Lewis , C. , Suffet , I. H. , Hoggatt , K. and Ritz , B. 2007 . Estimated effects of disinfection by-products on preterm birth in a population served by a single water utility . Environ. Health Perspect , 115 : 290 – 295 .
  • Lin , C. M. , Li , C. Y. and Mao , I. F. 2006 . Birth outcomes of infants born in areas with elevated ambient exposure to incinerator generated PCDD/Fs . Environ. Int. , 32 : 624 – 629 .
  • Llop , S. , Ballester , F. , Estarlich , M. , Esplugues , A. , Rebagliato , M. and Iniguez , C. 2010 . Preterm birth and exposure to air pollutants during pregnancy . Environ Res. , 110 : 778 – 785 .
  • Longnecker , M. P. , Klebanoff , M. A. , Zhou , H. and Brock , J. W. 2001 . Association between maternal serum concentration of the DDT metabolite DDE and preterm and small-for-gestational-age babies at birth . Lancet , 358 : 110 – 114 .
  • Longnecker , M. P. , Klebanoff , M. A. , Brock , J. W. and Guo , X. 2005 . Maternal levels of polychlorinated biphenyls in relation to preterm and small-for-gestational-age birth . Epidemiology , 16 : 641 – 647 .
  • Makri , A. , Goveia , M. , Balbus , J. and Parkin , R. 2004 . Children's susceptibility to chemicals: A review by developmental stage . J. Toxicol. Environ. Health B , 7 : 417 – 435 .
  • Maroziene , L. and Grazuleviciene , R. 2002 . Maternal exposure to low-level air pollution and pregnancy outcomes: A population-based study . Environ, Health , 1 : 6
  • Martin , J. A. 2011 . Control Centers for Disease, and Prevention . Preterm births—United States, 2007. MMWR Surveill. Summ , 60 : 78 – 79 . (suppl.)
  • McElrath , T. F. , Hecht , J. L. , Dammann , O. , Boggess , K. , Onderdonk , A. , Markenson , G. , Harper , M. , Delpapa , E. , Allred , E. N. and Leviton , A. 2008 . Pregnancy disorders that lead to delivery before the 28th week of gestation: An epidemiologic approach to classification . Am. J. Epidemiol , 168 : 980 – 989 . Elgan Study Investigators.
  • Meeker , J. D. , Hu , H. , Cantonwine , D. E. , Lamadrid-Figueroa , H. , Calafat , A. M. , Ettinger , A. S.m , Hernandez-Avila , M. , Loch-Caruso , R. and Tellez-Rojo , M. M. 2009 . Urinary phthalate metabolites in relation to preterm birth in Mexico city . Environ. Health Perspect , 117 : 1587 – 1592 .
  • Mukherjee , S. C. , Saha , K. C. , Pati , S. , Dutta , R. N. , Rahman , M. M. , Sengupta , M. K. , Ahamed , S. , Lodh , D. , Das , B. , Hossain , M. A. , Nayak , B. , Mukherjee , A. , Chakraborti , D. , Dulta , S. K. , Palit , S. K. , Kaies , I. , Barua , A. K. and Asad , K. A. 2005 . Murshidabad—One of the nine groundwater arsenic-affected districts of West Bengal, India. Part II: Dermatological, neurological, and obstetric findings . Clin. Toxicol. (Phila.) , 43 : 835 – 848 .
  • Myers , S. L. , Lobdell , D. T. , Liu , Z. , Xia , Y. , Ren , H. , Li , Y. , Kwok , R. K. , Mumford , J. L. and Mendola , P. 2010 . Maternal drinking water arsenic exposure and perinatal outcomes in inner Mongolia, China . J. Epidemiol. Commun. Health , 64 : 325 – 329 .
  • Neyeloff , J. L. , Fuchs , S. C. and Moreira , L. B. 2012 . Meta-analyses and Forest plots using a Microsoft Excel spreadsheet: Step-by-step guide focusing on descriptive data analysis . BMC Res. Notes , 5 : 52
  • Ning , Z. , Lobdell , D. T. , Kwok , R. K. , Liu , Z. , Zhang , S. , Ma , C. , Riediker , M. and Mumford , J. L. 2007 . Residential exposure to drinking water arsenic in Inner Mongolia, China . Toxicol. Appl. Pharmacol , 222 : 351 – 356 .
  • Nishijo , M. , Nakagawa , H. , Honda , R. , Tanebe , K. , Saito , S. , Teranishi , H. and Tawara , K. 2002 . Effects of maternal exposure to cadmium on pregnancy outcome and breast milk . Occup. Environ. Med , 59 : 394 – 396 . discussion 397
  • Nolan , L. A. , Nolan , J. M. , Shofer , F. S. , Rodway , N. V. and Emmett , E. A. 2009 . The relationship between birth weight, gestational age and perfluorooctanoic acid (PFOA)-contaminated public drinking water . Reprod. Toxicol , 27 : 231 – 238 .
  • Ochoa-Acuña , H. , Frankenberger , J. , Hahn , L. and Carbajo , C . 2009 . Drinking-water herbicide exposure in Indiana and prevalence of small-for-gestational-age and preterm delivery . Environ. Health Perspect , 117 : 1619 – 1624 .
  • Olsen , G. W. , Burris , J. M. , Ehresman , D. J. , Froehlich , J. W. , Seacat , A. M. , Butenhoff , J. L. and Zobel , L. R. 2007 . Half-life of serum elimination of perfluorooctanesulfonate, perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers . Environ. Health Perspect , 115 : 1298 – 1305 .
  • Patelarou , E. , Kargaki , S. , Stephanou , E. G. , Nieuwenhuijsen , M. , Sourtzi , P. , Gracia , E. , Chatzi , L. , Koutis , A. and Kogevinas , M. 2011 . Exposure to brominated trihalomethanes in drinking water and reproductive outcomes . Occup. Environ. Med , 68 : 438 – 445 .
  • Pathak , R. , Ahmed , R. S. , Tripathi , A. K. , Guleria , K. , Sharma , C. S. , Makhijani , S. D. and Banerjee , B. D. 2009 . Maternal and cord blood levels of organochlorine pesticides: association with preterm labor . Clin. Biochem , 42 : 746 – 749 .
  • Pirkle , J. L. , Brody , D. J. , Gunter , E. W. , Kramer , R. A. , Paschal , D. C. , Flegal , K. M. and Matte , T. D. 1994 . The decline in blood lead levels in the United States. The National Health and Nutrition Examination Surveys (NHANES) . J. Am. Med. Assoc , 272 : 284 – 291 .
  • Procianoy , R. S. and Schvartsman , S. 1981 . Blood pesticide concentration in mothers and their newborn infants. Relation to prematurity . Acta Paediatr. Scand , 70 : 925 – 928 .
  • Revich , B. , Aksel , E. , Ushakova , T. , Ivanova , I. , Zhuchenko , N. , Klyuev , N. , Brodsky , B. and Sotskov , Y. 2001 . Dioxin exposure and public health in Chapaevsk, Russia . Chemosphere , 43 : 951 – 966 .
  • Ribas-Fitó , N. , Sala , M. , Cardo , E. , Mazon , C. , De Muga , M. E. , Verdu , A. , Marco , E. , Grimalt , J. O. and Sunyer , J. 2002 . Association of hexachlorobenzene and other organochlorine compounds with anthropometric measures at birth . Pediatr. Res , 52 : 163 – 167 .
  • Rinsky , J. L. , Hopenhayn , C. , Golla , V. , Browning , S. and Bush , H. M. 2012 . Atrazine exposure in public drinking water and preterm birth . Public Health Rep , 127 : 72 – 80 .
  • Rivera-Nunez , Z. , Meliker , J. R. , Linder , A. M. and Nriagu , J. O. 2010 . Reliability of spot urine samples in assessing arsenic exposure . Int. J. Hyg. Environ. Health , 213 : 259 – 264 .
  • Salmasi , G. , Grady , R. , Jones , J. and McDonald , S. D. 2010 . Environmental tobacco smoke exposure and perinatal outcomes: A systematic review and meta-analyses . Acta Obstet. Gynecol. Scand , 89 : 423 – 441 .
  • Sathyanarayana , S. , Basso , O. , Karr , C. J. , Lozano , P. , Alavanja , M. , Sandler , D. P. and Hoppin , J. A. 2010 . Maternal pesticide use and birth weight in the agricultural health study . J. Agromedic , 15 : 127 – 136 .
  • Savitz , D. A. , Blackmore , C. A. and Thorp , J. M. 1991 . Epidemiologic characteristics of preterm delivery: Etiologic heterogeneity . Am. J. Obstet. Gynecol , 164 : 467 – 471 .
  • Savitz , D. A. , Andrews , K. W. and Pastore , L. M. 1995 . Drinking water and pregnancy outcome in central North Carolina: Source, amount, and trihalomethane levels . Environ. Health Perspect , 103 : 592 – 596 .
  • Savitz , D. A. 2008 . Invited commentary: Disaggregating preterm birth to determine etiology . Am. J. Epidemiol , 168 : 990 – 992 . discussion 993994
  • Savitz , D. A. , Stein , C. R. , Bartell , S. M. , Elston , B. , Gong , J. , Shin , H. M. and Wellenius , G. A. 2012a . Perfluorooctanoic acid exposure and pregnancy outcome in a highly exposed community . Epidemiology , 23 : 386 – 392 .
  • Savitz , D. A. , Stein , C. R. , Elston , B. , Wellenius , G. A. , Bartell , S. M. , Shin , H. M. , Vieira , V. M. and Fletcher , T. 2012b . Relationship of perfluorooctanoic acid exposure to pregnancy outcome based on birth records in the Mid-Ohio Valley . Environ. Health Perspect , 120 : 1201 – 1207 .
  • Saxena , M. C. , Siddiqui , M. K. , Seth , T. D. , Krishna Murti , C. R. , Bhargava , A. K. and Kutty , D. 1981 . Organochlorine pesticides in specimens from women undergoing spontaneous abortion, premature of full-term delivery . J. Anal. Toxicol , 5 : 6 – 9 .
  • Schisterman , E. F. , Whitcomb , B. W. , Louis , G. M. and Louis , T. A. 2005 . Lipid adjustment in the analysis of environmental contaminants and human health risks . Environ. Health Perspect , 113 : 853 – 857 .
  • Shah , P. S. and Balkhair , T. 2011 . Air pollution and birth outcomes: A systematic review . Environ. Int , 37 : 498 – 516 .
  • Silva , M. J. , Barr , D. B. , Reidy , J. A. , Malek , N. A. , Hodge , C. C. , Caudill , S. P. , Brock , J. W. , Needham , L. L. and Calafat , A. M. 2004 . Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999–2000 . Environ. Health Perspect , 112 : 331 – 338 .
  • Singh , V. K. , Singh , J. , Anand , M. , Kumar , P. , Patel , D. K. , Krishna Reddy , M. M. and Javed Siddiqui , M. K. 2008 . Comparison of polycyclic aromatic hydrocarbon levels in placental tissues of Indian women with full- and preterm deliveries . Int. J. Hyg. Environ. Health , 211 : 639 – 647 .
  • Slama , R. , Darrow , L. , Parker , J. , Woodruff , T. J. , Strickland , M. , Nieuwenhuijsen , M. , Glinianaia , S. , Hoggatt , K. J. , Kannan , S. , Hurley , F. , Kalinka , J. , Sram , R. , Brauer , M. , Wilhelm , M. , Heinrich , J. and Ritz , B. 2008 . Meeting report: Atmospheric pollution and human reproduction . Environ. Health Perspect , 116 : 791 – 798 .
  • Sonnenfeld , N. , Hertz-Picciotto , I. and Kaye , W. E. 2001 . Tetrachloroethylene in drinking water and birth outcomes at the US Marine Corps Base at Camp Lejeune, North Carolina . Am. J. Epidemiol , 154 : 902 – 908 .
  • Sowers , M. , Jannausch , M. , Scholl , T. , Li , W. , Kemp , F. W. and Bogden , J. D. 2002 . Blood lead concentrations and pregnancy outcomes . Arch. Environ. Health , 57 : 489 – 495 .
  • Sram , R. J. , Binkova , B. , Dejmek , J. and Bobak , M. 2005 . Ambient air pollution and pregnancy outcomes: A review of the literature . Environ. Health Perspect , 113 : 375 – 382 .
  • Stein , C. R. , Savitz , D. A. and Dougan , M. 2009 . Serum levels of perfluorooctanoic acid and perfluorooctane sulfonate and pregnancy outcome . Am. J. Epidemiol , 170 : 837 – 846 .
  • Stillerman , K. P. , Mattison , D. R. , Giudice , L. C. and Woodruff , T. J. 2008 . Environmental exposures and adverse pregnancy outcomes: A review of the science . Reprod. Sci , 15 : 631 – 650 .
  • Suzuki , Y. , Niwa , M. , Yoshinaga , J. , Mizumoto , Y. , Serizawa , S. and Shiraishi , H. 2010 . Prenatal exposure to phthalate esters and PAHs and birth outcomes . Environ. Int , 36 : 699 – 704 .
  • Torres-Arreola , L. , Berkowitz , G. , Torres-Sanchez , L. , Lopez-Cervantes , M. , Cebrian , M. E. , Uribe , M. and Lopez-Carrillo , L. 2003 . Preterm birth in relation to maternal organochlorine serum levels . Ann. Epidemiol , 13 : 158 – 162 .
  • Torres-Sánchez , L. E. , Berkowitz , G. , Lopez-Carrillo , L. , Torres-Arreola , L. , Rios , C. and Lopez-Cervantes , M. 1999 . Intrauterine lead exposure and preterm birth . Environ. Res , 81 : 297 – 301 .
  • Tuthill , G. F. and Schwalm , W. A. 1992 . Biased interacting self-avoiding walks on the four-simplex lattice . Phys. Rev. B Condens. Matter , 46 : 13722 – 13734 .
  • U.S. Department of Health and Human Services . 2006 . The health consequences of smoking: A report of the Surgeon General www.surgeongeneral.gov/library/reports/smokingconsequences/index.html
  • Vassilev , Z. P. , Robson , M. G. and Klotz , J. B. 2001 . Outdoor exposure to airborne polycyclic organic matter and adverse reproductive outcomes: A pilot study . Am. J. Ind. Med , 40 : 255 – 262 .
  • Vigeh , M. , Yokoyama , K. , Seyedaghamiri , Z. , Shinohara , A. , Matsukawa , T. , Chiba , M. and Yunesian , M. 2011 . Blood lead at currently acceptable levels may cause preterm labour . Occup. Environ. Med , 68 : 231 – 234 .
  • Villanueva , C. M. , Durand , G. , Coutte , M. B. , Chevrier , C. and Cordier , S. 2005 . Atrazine in municipal drinking water and risk of low birth weight, preterm delivery, and small-for-gestational-age status . Occup. Environ. Med , 62 : 400 – 405 .
  • Villanueva , C. M. , Gracia-Lavedan , E. , Ibarluzea , J. , Santa Marina , L. , Ballester , F. , Llop , S. , Tardon , A. , Fernandez , M. F. , Freire , C. , Goni , F. , Basagana , X. , Kogevinas , M. , Grimalt , J. O. and Sunyer , J. 2011 . Exposure to trihalomethanes through different water uses and birth weight, small for gestational age, and preterm delivery in Spain . Environ. Health Perspect , 119 : 1824 – 1830 .
  • Vrijheid , M. , Casas , M. , Bergstrom , A. , Carmichael , A. , Cordier , S. , Eggesbo , M. , Eller , E. , Fantini , M. P. , Fernandez , M. F. , Fernandez-Somoano , A. , Gehring , U. , Grazuleviciene , R. , Hohmann , C. , Karvonen , A. M. , Keil , T. , Kogevinas , M. , Koppen , G. , Kramer , U. , Kuehni , C. E. , Magnus , P. , Majewska , R. , Andersen , A. M. , Patelarou , E. , Petersen , M. S. , Pierik , F. H. , Polanska , K. , Porta , D. , Richiardi , L. , Santos , A. C. , Slama , R. , Sram , R. J. , Thijs , C. , Tischer , C. , Toft , G. , Trnovec , T. , Vandentorren , S. , Vrijkotte , T. G. , Wilhelm , M. , Wright , J. and Nieuwenhuijsen , M. 2012 . European birth cohorts for environmental health research . Environ. Health Perspect , 120 : 29 – 37 .
  • Wassermann , M. , Ron , M. , Bercovici , B. , Wassermann , D. , Cucos , S. and Pines , A. 1982 . Premature delivery and organochlorine compounds: Polychlorinated biphenyls and some organochlorine insecticides . Environ. Res , 28 : 106 – 112 .
  • Whitworth , K. W. , Haug , L. S. , Baird , D. D. , Becher , G. , Hoppin , J. A. , Skjaerven , R. , Thomsen , C. , Eggesbo , M. , Travlos , G. , Wilson , R. , Cupul-Uicab , L. A. , Brantsaeter , A. L. and Longnecker , M. P. 2012 . Perfluorinated compounds in relation to birth weight in the Norwegian mother and child cohort study . Am. J. Epidemiol , 175 : 1209 – 1216 .
  • Whyatt , R. M. , Adibi , J. J. , Calafat , A. M. , Camann , D. E. , Rauh , V. , Bhat , H. K. , Perera , F. P. , Andrews , H. , Just , A. C. , Hoepner , L. , Tang , D. and Hauser , R. 2009 . Prenatal di (2-ethylhexyl)phthalate exposure and length of gestation among an inner-city cohort . Pediatrics , 124 : e1213 – e1220 .
  • Wigle , D. T. , Arbuckle , T. E. , Turner , M. C. , Berube , A. , Yang , Q. , Liu , S. and Krewski , D. 2008 . Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants . J. Toxicol. Environ. Health B , 11 : 373 – 517 .
  • Wilhelm , M. , Ghosh , J. K. , Su , J. , Cockburn , M. , Jerrett , M. and Ritz , B. 2011 . Traffic-related air toxics and preterm birth: AQ population-based case-control study in Los Angeles County, California . Environ. Health , 10 : 89
  • Windham , G. and Fenster , L. 2008 . Environmental contaminants and pregnancy outcomes . Fertil. Steril , 89 : e111 – e116 . discussion e117
  • Wojtyniak , B. J. , Rabczenko , D. , Jonsson , B. A. , Zvezday , V. , Pedersen , H. S. , Rylander , L. , Toft , G. , Ludwicki , J. K. , Goralczyk , K. , Lesovaya , A. , Hagmar , L. and Bonde , J. P. 2010 . Association of maternal serum concentrations of 2, 2', 4, 4'5, 5'-hexachlorobiphenyl (CB-153) and 1, 1-dichloro-2, 2-bis (P-chlorophenyl)-ethylene (P, p'-DDE) levels with birth weight, gestational age and preterm births in Inuit and European populations . Environ. Health , 9 : 56
  • Wolff , M. S. , Engel , S. M. , Berkowitz , G. S. , Ye , X. , Silva , M. J. , Zhu , C. , Wetmur , J. and Calafat , A. M. 2008 . Prenatal phenol and phthalate exposures and birth outcomes . Environ. Health Perspect , 116 : 1092 – 1097 .
  • Wood , S. L. , Jarrell , J. J. , Swaby , C. and Chan , S. 2007 . Endocrine disruptors and spontaneous premature labor: A case control study . Environ. Health , 6 : 35
  • Wright , J. M. , Schwartz , J. and Dockery , D. W. 2003 . Effect of trihalomethane exposure on fetal development . Occup. Environ. Med , 60 : 173 – 180 .
  • Wright , J. M. , Schwartz , J. and Dockery , D. W. 2004 . The effect of disinfection by-products and mutagenic activity on birth weight and gestational duration . Environ. Health Perspect , 112 : 920 – 925 .
  • Wu , K. , Xu , X. , Liu , J. , Guo , Y. , Li , Y. and Huo , X. 2010 . Polybrominated diphenyl ethers in umbilical cord blood and relevant factors in neonates from Guiyu, China . Environ. Sci. Technol , 44 : 813 – 819 .
  • Wu , K. , Xu , X. , Peng , L. , Liu , J. , Guo , Y. and Huo , X. 2012 . Association between maternal exposure to perfluorooctanoic acid (PFOA) from electronic waste recycling and neonatal health outcomes . Environ. Int , 48 : 1 – 8 .
  • Xue , F. , Holzman , C. , Rahbar , M. H. , Trosko , K. and Fischer , L. 2007 . Maternal fish consumption, mercury levels, and risk of preterm delivery . Environ. Health Perspect , 115 : 42 – 47 .
  • Yang , C. Y. , Cheng , B. H. , Tsai , S. S. , Wu , T. N. , Lin , M. C. and Lin , K. C. 2000 . Association between chlorination of drinking water and adverse pregnancy outcome in Taiwan . Environ. Health Perspect , 108 : 765 – 768 .
  • Yang , C. Y. , Chang , C. C. , Tsai , S. S. , Chuang , H. Y. , Ho , C. K. and Wu , T. N. 2003 . Arsenic in drinking water and adverse pregnancy outcome in an arseniasis-endemic area in northeastern Taiwan . Environ. Res , 91 : 29 – 34 .
  • Yang , C. Y. 2004 . Drinking water chlorination and adverse birth outcomes in Taiwan . Toxicology , 198 : 249 – 254 .
  • Yang , C. Y. , Xiao , Z. P. , Ho , S. C. , Wu , T. N. and Tsai , S. S. 2007 . Association between trihalomethane concentrations in drinking water and adverse pregnancy outcome in Taiwan . Environ. Res , 104 : 390 – 395 .
  • Zhang , X. and Kramer , M. S. 2009 . Variations in mortality and morbidity by gestational age among infants born at term . J. Pediatr , 154 : 358 – 362 . 362, e351
  • Zhang , Y. L. , Zhao , Y. C. , Wang , J. X. , Zhu , H. D. , Liu , Q. F. , Fan , Y. G. , Wang , N. F. , Zhao , J. H. , Liu , H. S. , Ou-Yang , L. , Liu , A. P. and Fan , T. Q. 2004 . Effect of environmental exposure to cadmium on pregnancy outcome and fetal growth: A study on healthy pregnant women in China . J. Environ. Sci. Health A Tox. Hazard Subst. Environ. Eng , 39 : 2507 – 2515 .
  • Zhu , M. , Fitzgerald , E. F. , Gelberg , K. H. , Lin , S. and Druschel , C. M. 2010 . Maternal low-level lead exposure and fetal growth . Environ. Health Perspect , 118 : 1471 – 1475 .

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