581
Views
38
CrossRef citations to date
0
Altmetric
Original Articles

Five years update on relationships between malignant pleural mesothelioma and exposure to asbestos and other elongated mineral particles

, , , , &

References

  • Abdel-Rahman, M. H., R. Pilarski, C. M. Cebulla, J. B. Massengill, B. N. Christopher, G. Boru, P. Hovland, and F. H. Davidorf. 2011. Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers. Journal of Medical Genetics 48:856–59. doi:10.1136/jmedgenet-2011-100156
  • Abdullayev, E., and Y. Lvov. 2011. Halloysite clay nanotubes for controlled release of protective agents. Journal of Nanoscience and Nanotechnology 11:10007–26. doi:10.1166/jnn.2011.5724
  • Agudo, A., C. A. Gonzalez, M. J. Bleda, J. Ramirez, S. Hernandez, F. Lopez, A. Calleja, R. Panades, D. Turuguet, A. Escolar, M. Beltran, and J. E. Gonzalez-Moya. 2000. Occupation and risk of malignant pleural mesothelioma: A case-control study in Spain. American Journal of Industrial Medicine 37:159–68. doi:10.1002/(SICI)1097-0274(200002)37:2<159::AID-AJIM1>3.0.CO;2-0
  • Aguilar-Madrid, G., E. Robles-Perez, C. A. Juarez-Perez, I. Alvarado-Cabrero, F. G. Rico-Mendez, and K. G. Javier. 2010. Case-control study of pleural mesothelioma in workers with social security in Mexico. American Journal of Industrial Medicine 53:241–51.
  • Altomare, D. A., C. W. Menges, J. Xu, J. Pei, L. Zhang, A. Tadevosyan, E. Neumann-Domer, Z. Liu, M. Carbone, I. Chudoba, A. J. Klein-Szanto, and J. R. Testa. 2011. Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis. PLoS ONE 6:e18828. doi:10.1371/journal.pone.0018828
  • Andersen, M., M. Grauslund, J. Ravn, J. B. Sorensen, C. B. Andersen, and E. Santoni-Rugiu. 2014. Diagnostic potential of miR-126, miR-143, miR-145, and miR-652 in malignant pleural mesothelioma. The Journal of Molecular Diagnostics 16:418–30. doi:10.1016/j.jmoldx.2014.03.002
  • Andrici, J., A. Sheen, L. Sioson, K. Wardell, A. Clarkson, N. Watson, M. S. Ahadi, M. Farzin, C. W. Toon, and A. J. Gill. 2015. Loss of expression of BAP1 is a useful adjunct, which strongly supports the diagnosis of mesothelioma in effusion cytology. Modern Pathology 28:1360–68. doi:10.1038/modpathol.2015.87
  • Antao, V. C., T. C. Larson, and D. K. Horton. 2012. Libby vermiculite exposure and risk of developing asbestos-related lung and pleural diseases. Current Opinion in Pulmonary Medicine 18:161–67. doi:10.1097/MCP.0b013e32834e897d
  • Arzt, L., F. Quehenberger, I. Halbwedl, T. Mairinger, and H. H. Popper. 2014. BAP1 protein is a progression factor in malignant pleural mesothelioma. Pathology Oncology Research 20:145–51. doi:10.1007/s12253-013-9677-2
  • Aschberger, K., H. J. Johnston, V. Stone, R. J. Aitken, S. M. Hankin, S. A. Peters, C. L. Tran, and F. M. Christensen. 2010. Review of carbon nanotubes toxicity and exposure—Appraisal of human health risk assessment based on open literature. Critical Reviews in Toxicology 40:759–90. doi:10.3109/10408444.2010.506638
  • Aust, A., P. M. Cook, and R. F. Dodson. 2011. Morphological and chemical mehanisms of elongated particle toxicities. Journal of Toxicology and Environmental Health, Part B 14:40–75. doi:10.1080/10937404.2011.556046
  • Bang, K. M., J. M. Mazurek, J. M. Wood, and S. A. Hendricks. 2014. Diseases attributable to asbestos exposure: Years of potential life lost, United States, 1999–2010. American Journal of Industrial Medicine 57:38–48. doi:10.1002/ajim.v57.1
  • Baumann, F., B. J. Buck, R. V. Metcalf, B. T. McLaurin, D. J. Merkler, and M. Carbone. 2015a. The presence of asbestos in the natural environment is likely related to mesothelioma in young individuals and women from southern Nevada. Journal of Thoracic Oncology 10:731–37. doi:10.1097/JTO.0000000000000506
  • Baumann, F., E. Flores, A. Napolitano, S. Kanodia, E. Taioli, H. Pass, H. Yang, and M. Carbone. 2015b. Mesothelioma patients with germline BAP1 mutations have 7-fold improved long-term survival. Carcinogenesis 36:76–81. doi:10.1093/carcin/bgu227
  • Baumann, F., P. Maurizot, M. Mangeas, J. P. Ambrosi, J. Douwes, and B. Robineau. 2011. Pleural mesothelioma in New Caledonia: Associations with environmental risk factors. Environmental Health Perspectives 119:695–700. doi:10.1289/ehp.1002862
  • Below, J. E., N. J. Cox, N. K. Fukagawa, A. Hirvonen, and J. R. Testa. 2011. Factors that impact susceptibility to fiber-induced health effects. Journal of Toxicology and Environmental Health, Part B 14:246–66. doi:10.1080/10937404.2011.556052
  • Betti, M., E. Casalone, D. Ferrante, A. Romanelli, F. Grosso, S. Guarrera, L. Righi, S. Vatrano, G. Pelosi, R. Libener, D. Mirabelli, R. Boldorini, C. Casadio, M. Papotti, G. Matullo, C. Magnani, and I. Dianzani. 2015. Inference on germline BAP1 mutations and asbestos exposure from the analysis of familial and sporadic mesothelioma in a high-risk area. Genes Chromosomes Cancer 54:51–62. doi:10.1002/gcc.v54.1
  • Biggeri, A., R. Pasetto, S. Belli, C. Bruno, G. Di Maria, M. Mastrantonio, S. Trinca, R. Uccelli, and P. Comba. 2004. Mortality from chronic obstructive pulmonary disease and pleural mesothelioma in an area contaminated by natural fiber (fluoro-edenite). Scandinavian Journal of Work, Environment & Health 30:249–52. doi:10.5271/sjweh.786
  • Boffetta, P., K. Donaldson, S. Moolgavkar, and J. S. Mandel. 2014. A systematic review of occupational exposure to synthetic vitreous fibers and mesothelioma. Critical Reviews in Toxicology 44:436–49. doi:10.3109/10408444.2014.899558
  • Borczuk, A. C., J. Pei, R. N. Taub, B. Levy, O. Nahum, J. Chen, K. Chen, and J. R. Testa. 2016. Genome-wide analysis of abdominal and pleural malignant mesothelioma with DNA arrays reveals both common and distinct regions of copy number alteration. Cancer Biology & Therapy 17:328–35.
  • Bott, M., M. Brevet, B. S. Taylor, S. Shimizu, T. Ito, L. Wang, J. Creaney, R. A. Lake, M. F. Zakowski, B. Reva, C. Sander, R. Delsite, S. Powell, Q. Zhou, R. Shen, A. Olshen, V. Rusch, and M. Ladanyi. 2011. The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma. Nature Genetics 43:668–72. doi:10.1038/ng.855
  • Boulanger, G., P. Andujar, J. C. Pairon, M. A. Billon-Galland, C. Dion, P. Dumortier, P. Brochard, A. Sobaszek, P. Bartsch, C. Paris, and M. C. Jaurand. 2014. Quantification of short and long asbestos fibers to assess asbestos exposure: A review of fiber size toxicity. Environmental Health 13:59. doi:10.1186/1476-069X-13-59
  • Bruno, C., R. Tumino, L. Fazzo, G. Cascone, A. Cernigliaro, M. De Santis, M. C. Giurdanella, C. Nicita, P. C. Rollo, S. Scondotto, E. Spata, A. Zona, and P. Comba. 2014. Incidence of pleural mesothelioma in a community exposed to fibres with fluoro-edenitic composition in Biancavilla (Sicily, Italy). Annali dell’istituto Superiore di Sanita 50:111–18.
  • Bueno, R., E. W. Stawiski, L. D. Goldstein, S. Durinck, A. De Rienzo, Z. Modrusan, F. Gnad, T. T. Nguyen, B. S. Jaiswal, L. R. Chirieac, D. Sciaranghella, N. Dao, C. E. Gustafson, K. J. Munir, J. A. Hackney, A. Chaudhuri, R. Gupta, J. Guillory, K. Toy, C. Ha, Y. J. Chen, J. Stinson, S. Chaudhuri, N. Zhang, T. D. Wu, D. J. Sugarbaker, F. J. De Sauvage, W. G. Richards, and S. Seshagiri. 2016. Comprehensive genomic analysis of malignant pleural mesothelioma identifies recurrent mutations, gene fusions and splicing alterations. Nature Genetics. 48:407–16.
  • Bunderson-Schelvan, M., J. C. Pfau, R. Crouch, and A. Holian. 2011. Nonpulmonary outcomes of asbestos exposure. Journal of Toxicology and Environmental Health, Part B 14:122–52. doi:10.1080/10937404.2011.556048
  • Camargo, M. C., L. T. Stayner, K. Straif, M. Reina, U. Al-Alem, P. A. Demers, and P. J. Landrigan. 2011. Occupational exposure to asbestos and ovarian cancer: A meta-analysis. Environmental Health Perspectives 119:1211–17. doi:10.1289/ehp.1003283
  • Camiade, E., C. Gramond, M. A. Jutand, S. Audignon, M. Rinaldo, E. Imbernon, D. Luce, F. Galateau-Salle, P. Astoul, J. C. Pairon, P. Brochard, and A. Lacourt. 2013. Characterization of a French series of female cases of mesothelioma. American Journal of Industrial Medicine 56:1307–16.
  • Carbone, M., Y. I. Baris, P. Bertino, B. Brass, S. Cornertpay, A. Dogan, G. Gaudino, S. Jube, S. Kanodia, C. R. Partridge, H. Pass, Z. Rivera, I. Steele, M. Tuncer, S. Way, H. Yang, and A. Miller. 2011. Erionite exposure in North Dakota and Turkish villages with mesothelioma Proceedings of the National Academy of Sciences 108:13618–23. doi:10.1073/pnas.1105887108
  • Carlin, D. J., T. C. Larson, J. C. Pfau, S. H. Gavett, A. Shukla, A. Miller, and R. Hines. 2015. Current research and opportunities to address environmental asbestos exposures. Environmental Health Perspectives 123:A194–97. doi:10.1289/ehp.1409662
  • Case, B. W., J. L. Abraham, G. Meeker, F. D. Pooley, and K. E. Pinkerton. 2011. Applying definitions of “asbestos” to environmental and “low-dose” exposure levels and health effects, particularly malignant mesothelioma. Journal of Toxicology and Environmental Health, Part B 14:3–39. doi:10.1080/10937404.2011.556045
  • Cheng, Y. Y., M. B. Kirschner, N. C. Cheng, S. Gattani, S. Klebe, J. J. Edelman, M. P. Vallely, B. C. McCaughan, H. C. Jin, N. Van Zandwijk, and G. Reid. 2013. ZIC1 is silenced and has tumor suppressor function in malignant pleural mesothelioma. Journal of Thoracic Oncology 8:1317–28. doi:10.1097/JTO.0b013e3182a0840a
  • Chirieac, L. R., J. A. Barletta, B. Y. Yeap, W. G. Richards, T. Tilleman, R. Bueno, E. H. Baldini, J. Godleski, and D. J. Sugarbaker. 2013. Clinicopathologic characteristics of malignant mesotheliomas arising in patients with a history of radiation for Hodgkin and non-Hodgkin lymphoma. Journal of Clinical Oncology 31:4544–49. doi:10.1200/JCO.2013.49.9616
  • Christensen, B. C., E. A. Houseman, J. J. Godleski, C. J. Marsit, J. L. Longacker, C. R. Roelofs, M. R. Karagas, M. R. Wrensch, R. F. Yeh, H. H. Nelson, J. L. Wiemels, S. Zheng, J. K. Wiencke, R. Bueno, D. J. Sugarbaker, and K. T. Kelsey. 2009. Epigenetic profiles distinguish pleural mesothelioma from normal pleura and predict lung asbestos burden and clinical outcome. Cancer Research 69:227–34. doi:10.1158/0008-5472.CAN-08-2586
  • Christensen, B. C., E. A. Houseman, G. M. Poage, J. J. Godleski, R. Bueno, D. J. Sugarbaker, J. K. Wiencke, H. H. Nelson, C. J. Marsit, and K. T. Kelsey. 2010. Integrated profiling reveals a global correlation between epigenetic and genetic alterations in mesothelioma. Cancer Research 70:5686–94. doi:10.1158/0008-5472.CAN-10-0190
  • Churg, A., T. Allen, A. C. Borczuk, P. T. Cagle, F. Galateau-Salle, H. Hwang, B. Murer, V. V. Murty, N. Ordonez, H. D. Tazelaar, and M. Wick. 2014. Well-differentiated papillary mesothelioma with invasive foci. American Journal of Surgical Pathology 38:990–98. doi:10.1097/PAS.0000000000000200
  • Cioce, M., F. Ganci, V. Canu, A. Sacconi, F. Mori, C. Canino, E. Korita, B. Casini, G. Alessandrini, A. Cambria, M. A. Carosi, R. Blandino, V. Panebianco, F. Facciolo, P. Visca, S. Volinia, P. Muti, S. Strano, C. M. Croce, H. I. Pass, and G. Blandino. 2014. Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma. Oncogene 33:5319–31. doi:10.1038/onc.2013.476
  • Clin, B., F. Morlais, G. Launoy, A. V. Guizard, B. Dubois, V. Bouvier, N. Desoubeaux, M. F. Marquignon, C. Raffaelli, C. Paris, F. Galateau-Salle, L. Guittet, and M. Letourneux. 2011. Cancer incidence within a cohort occupationally exposed to asbestos: A study of dose-response relationships. Occupational and Environmental Medicine 68:832–36. doi:10.1136/oem.2010.059790
  • Comba, P., A. Gianfagna, and L. Paoletti. 2003. Pleural mesothelioma cases in Biancavilla are related to a new fluoro-edenite fibrous amphibole. Archives of Environmental Health 58:229–32. doi:10.3200/AEOH.58.4.229-232
  • Comertpay, S., S. Pastorino, M. Tanji, R. Mezzapelle, O. Strianese, A. Napolitano, F. Baumann, T. Weigel, J. Friedberg, P. Sugarbaker, T. Krausz, E. Wang, A. Powers, G. Gaudino, S. Kanodia, H. I. Pass, B. L. Parsons, H. Yang, and M. Carbone. 2014. Evaluation of clonal origin of malignant mesothelioma. Journal of Translational Medicine 12:301. doi:10.1186/s12967-014-0301-3
  • Cooke, W. E. 1924. Fibrosis of the lungs due to the inhalation of asbestos dust. British Medical Journal 2:140–42, 147. doi:10.1136/bmj.2.3317.147
  • Crovella, S., A. M. Bianco, J. Vuch, L. Zupin, R. R. Moura, E. Trevisan, M. Scneider, A. Brollo, E. M. Nicastro, A. Cosenzi, G. Zabucchi, and V. Borelli. 2016. Iron sugnature in asbestos-induced malignant pleural mesothelioma: A population-based study. Journal of Toxicology and Environmental Health, Part A 79:129–41. doi:10.1080/15287394.2015.1123452
  • Cyphert, J. M., D. J. Carlin, A. Nyska, M. C. Schladweiler, A. D. Ledbetter, J. H. Shannahan, U. P. Kodavanti, and S. H. Gavett. 2015. Comparative long-term toxicity of Libby amphibole and amosite asbestos in rats after single or multiple intratracheal exposures. Journal of Toxicology and Environmental Health, Part A 78:151–65. doi:10.1080/15287394.2014.947455
  • Cyphert, J. M., M. A. McGee, A. Nyska, M. C. Schladweiler, A. D. U. P. Kodavanti, and S. H. Gavett. 2016. long-term toxicity of naturally occurring asbestos in male Fischer 344 rats. Journal of Toxicology and Environmental Health, Part A 79:49–60. doi:10.1080/15287394.2015.1099123
  • Cyphert, J. M., A. Nyska, R. K. Mahoney, M. C. Schladweiler, U. P. Kodavanti, and S. H. Gavett. 2012. Sumas Mountain chrysotile induces greater lung fibrosis in Fischer 344 rats than Libby amphibole, El Dorado tremolite, and Ontario ferroactinolite. Toxicological Sciences 130:405–15. doi:10.1093/toxsci/kfs249
  • Davidson, B. 2015. Prognostic factors in malignant pleural mesothelioma. Human Pathology 46:789–804. doi:10.1016/j.humpath.2015.02.006
  • Dawson, A., A. Gibbs, K. Browne, F. Pooley, and M. Griffiths. 1992. Familial mesothelioma. Details of 17 cases with histopathologic findings and mineral analysis. Cancer 70:1183–87. doi:10.1002/(ISSN)1097-0142
  • de Assis, L. V., J. Locatelli, and M. C. Isoldi. 2014. The role of key genes and pathways involved in the tumorigenesis of malignant mesothelioma. Biochimica et Biophysica Acta 1845:232–47.
  • de Reynies, A., M. C. Jaurand, A. Renier, G. Couchy, I. Hysi, N. Elarouci, F. Galateau-Salle, M. C. Copin, P. Hofman, A. Cazes, P. Andujar, S. Imbeaud, F. Petel, J. C. Pairon, F. Le Pimpec-Barthes, J. Zucman-Rossi, and D. Jean. 2014. Molecular classification of malignant pleural mesothelioma: Identification of a poor prognosis subgroup linked to the epithelial-to-mesenchymal transition. Clinical Cancer Research 20:1323–34. doi:10.1158/1078-0432.CCR-13-2429
  • De Rienzo, A., W. G. Richards, B. Y. Yeap, M. H. Coleman, P. E. Sugarbaker, L. R. Chirieac, Y. E. Wang, J. Quackenbush, R. V. Jensen, and R. Bueno. 2013. Sequential binary gene ratio tests define a novel molecular diagnostic strategy for malignant pleural mesothelioma. Clinical Cancer Research 19:2493–502. doi:10.1158/1078-0432.CCR-12-2117
  • Delgermaa, V., K. Takahashi, E. K. Park, G. V. Le, T. Hara, and T. Sorahan. 2011. Global mesothelioma deaths reported to the World Health Organization between 1994 and 2008. Bulletin of the World Health Organization 89:716–24. doi:10.2471/BLT.00.000000
  • Doll, R. 1955. Mortality from lung cancer in asbestos workers. British Journal of Industrial Medicine 12:81–86.
  • Donaldson, K., and C. A. Poland. 2012. Inhaled nanoparticles and lung cancer - what we can learn from conventional particle toxicology. Swiss Medical Weekly 142:w13547.
  • Dunning, K. K., S. Adjei, L. Levin, A. M. Rohs, T. Hilbert, E. Borton, V. Kapil, C. Rice, G. K. Lemasters, and J. E. Lockey. 2012. Mesothelioma associated with commercial use of vermiculite containing Libby amphibole. Journal of Occupational and Environmental Medicine 54:1359–63. doi:10.1097/JOM.0b013e318250b5f5
  • Fang, R., N. Le, and P. Band. 2011. Identification of occupational cancer risks in British Columbia, Canada: A population-based case-control study of 1,155 cases of colon cancer. International Journal of Environmental Research and Public Health 8:3821–43. doi:10.3390/ijerph8103821
  • Farioli, A., F. S. Violante, S. Mattioli, S. Curti, and D. Kriebel. 2013. Risk of mesothelioma following external beam radiotherapy for prostate cancer: A cohort analysis of SEER database. Cancer Causes and Control 24:1535–45. doi:10.1007/s10552-013-0230-0
  • Farzin, M., C. W. Toon, A. Clarkson, L. Sioson, N. Watson, J. Andrici, and A. J. Gill. 2015. Loss of expression of BAP1 predicts longer survival in mesothelioma. Pathology 47:302–7. doi:10.1097/PAT.0000000000000250
  • Fatkhutdinova, L. M., T. O. Khaliullin, and A. A. Shvedova. 2015. Carbon nanotubes exposure risk assessment: From toxicology to epidemiologic studies (Overview of the current problem). Nanotechnologies in Russia 10:501–9. doi:10.1134/S1995078015030064
  • Favoni, R. E., A. Daga, P. Malatesta, and T. Florio. 2012. Preclinical studies identify novel targeted pharmacological strategies for treatment of human malignant pleural mesothelioma. British Journal of Pharmacology 166:532–53. doi:10.1111/j.1476-5381.2012.01873.x
  • Felley-Bosco, E., and R. Stahel. 2014. Hippo/YAP pathway for targeted therapy. Translational Lung Cancer Research 3:75–83.
  • Ferrante, D., D. Mirabelli, S. Tunesi, B. Terracini, and C. Magnani. 2016. Pleural mesothelioma and occupational and non-occupational asbestos exposure: A case-control study with quantitative risk assessment. Occupational and Environmental Medicine. 73:147–153.
  • Fleury-Feith, J., C. Lecomte, A. Renier, M. Matrat, L. Kheuang, V. Abramowski, F. Levy, A. Janin, M. Giovannini, and M. C. Jaurand. 2003. Hemizygosity of Nƒ2 is associated with increased susceptibility to asbestos-induced peritoneal tumours. Oncogene 22:3799–805. doi:10.1038/sj.onc.1206593
  • Forbes, S. A., D. Beare, P. Gunasekaran, K. Leung, N. Bindal, H. Boutselakis, M. Ding, S. Bamford, C. Cole, S. Ward, C. Y. Kok, M. Jia, T. De, J. W. Teague, M. R. Stratton, U. McDermott, and P. J. Campbell. 2015. COSMIC: Exploring the world’s knowledge of somatic mutations in human cancer. Nucleic Acids Research 43:D805–11. doi:10.1093/nar/gku1075
  • Fortunato, L., and L. Rushton. 2015. Stomach cancer and occupational exposure to asbestos: A meta-analysis of occupational cohort studies. British Journal of Cancer 112:1805–15. doi:10.1038/bjc.2014.599
  • Fox, S. A., A. K. Richards, I. Kusumah, V. Perumal, E. M. Bolitho, S. E. Mutsaers, and A. M. Dharmarajan. 2013. Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells. Biochemical and Biophysical Research Communications 440:82–87. doi:10.1016/j.bbrc.2013.09.025
  • Frank, A. L., and T. K. Joshi. 2014. The global spread of asbestos. Annals of Global Health 80:257–62. doi:10.1016/j.aogh.2014.09.016
  • Frischknecht, L., M. Meerang, A. Soltermann, R. Stahel, H. Moch, B. Seifert, W. Weder, and I. Opitz. 2015. Importance of excision repair cross-complementation group 1 and ribonucleotide reductase M1 as prognostic biomarkers in malignant pleural mesothelioma treated with platinum-based induction chemotherapy followed by surgery. Journal of Thoracic and Cardiovascular Surgery 149:1539–46.e1531. doi:10.1016/j.jtcvs.2015.01.065
  • Frost, G. 2013. The latency period of mesothelioma among a cohort of British asbestos workers (1978–2005). British Journal of Cancer 109:1965–73. doi:10.1038/bjc.2013.514
  • Galateau-Salle, F., J. M. Vignaud, L. Burke, A. Gibbs, E. Brambilla, R. Attanoos, M. Goldberg, and G. Launoy. 2004. Well-differentiated papillary mesothelioma of the pleura: A series of 24 cases. American Journal of Surgical Pathology 28:534–40. doi:10.1097/00000478-200404000-00013
  • Genaidy, A., T. Tolaymat, R. Sequeira, M. Rinder, and D. Dionysiou. 2009. Health effects of exposure to carbon nanofibers: Systematic review, critical appraisal, meta analysis and research to practice perspectives. Science of the Total Environment 407:3686–701. doi:10.1016/j.scitotenv.2008.12.025
  • Ghani, F. I., H. Yamazaki, S. Iwata, T. Okamoto, K. Aoe, K. Okabe, Y. Mimura, N. Fujimoto, T. Kishimoto, T. Yamada, C. W. Xu, and C. Morimoto. 2011. Identification of cancer stem cell markers in human malignant mesothelioma cells. Biochemical and Biophysical Research Communications 404:735–42. doi:10.1016/j.bbrc.2010.12.054
  • Gordon, G. J., L. Dong, B. Y. Yeap, W. G. Richards, J. N. Glickman, H. Edenfield, M. Mani, R. Colquitt, G. Maulik, B. Van Oss, D. J. Sugarbaker, and R. Bueno. 2009. Four-gene expression ratio test for survival in patients undergoing surgery for mesothelioma. Journal of the National Cancer Institute 101:678–86. doi:10.1093/jnci/djp061
  • Gordon, G. J., R. V. Jensen, L. L. Hsiao, S. R. Gullans, J. E. Blumenstock, W. G. Richards, M. T. Jaklitsch, D. J. Sugarbaker, and R. Bueno. 2003. Using gene expression ratios to predict outcome among patients with mesothelioma. Journal of the National Cancer Institute 95:598–605. doi:10.1093/jnci/95.8.598
  • Gordon, G. J., G. N. Rockwell, P. A. Godfrey, R. V. Jensen, J. N. Glickman, B. Y. Yeap, W. G. Richards, D. J. Sugarbaker, and R. Bueno. 2005. Validation of genomics-based prognostic tests in malignant pleural mesothelioma. Clinical Cancer Research 11:4406–14. doi:10.1158/1078-0432.CCR-04-2181
  • Goswami, E., V. Craven, D. L. Dahlstrom, D. Alexander, and F. Mowat. 2013. Domestic asbestos exposure: A review of epidemiologic and exposure data. International Journal of Environmental Research and Public Health 10:5629–70. doi:10.3390/ijerph10115629
  • Goto, Y., K. Shinjo, Y. Kondo, L. Shen, M. Toyota, H. Suzuki, W. Gao, B. An, M. Fujii, H. Murakami, H. Osada, T. Taniguchi, N. Usami, M. Kondo, Y. Hasegawa, K. Shimokata, K. Matsuo, T. Hida, N. Fujimoto, T. Kishimoto, J. P. Issa, and Y. Sekido. 2009. Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Research 69:9073–82. doi:10.1158/0008-5472.CAN-09-1595
  • Greim, H., M. J. Utell, L. D. Maxim, and R. Niebo. 2014. Perspectives on refractory ceramic fiber (RCF) carcinogenicity: Comparisons with other fibers. Inhalation Toxicology 26:789–810. doi:10.3109/08958378.2014.953276
  • Grosse, Y., D. Loomis, K. Z. Guyton, B. Lauby-Secretan, F. El Ghissassi, V. Bouvard, L. Benbrahim-Tallaa, N. Guha, C. Scoccianti, H. Mattock, and K. Straif. 2014. Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes. Lancet Oncology 15:1427–28. doi:10.1016/S1470-2045(14)71109-X
  • Guo, G., J. Chmielecki, C. Goparaju, A. Heguy, I. Dolgalev, M. Carbone, S. Seepo, M. Meyerson, and H. I. Pass. 2015. Whole exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A and CUL1 in malignant pleural mesothelioma. Cancer Research 75:264–69. doi:10.1158/0008-5472.CAN-14-1008
  • Hillegass, J. M., J. M. Miller, M. B. MacPherson, C. M. Westbom, M. Sayan, J. K. Thompson, S. L. Macura, T. N. Perkins, S. L. Beuschel, V. Alexeeva, H. I. Pass, C. Steele, B. T. Mossman, and A. Shukla. 2013. Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells. Particle and Fibre Toxicology 10:39. doi:10.1186/1743-8977-10-39
  • Hillerdal, G. 1999. Mesothelioma: Cases associated with non-occupational and low dose exposures. Occupational and Environmental Medicine 56:505–13. doi:10.1136/oem.56.8.505
  • Hoang, C. D., J. D’Cunha, M. G. Kratzke, C. E. Casmey, S. P. Frizelle, M. A. Maddaus, and R. A. Kratzke. 2004. Gene expression profiling identifies matriptase overexpression in malignant mesothelioma. Chest 125:1843–52. doi:10.1378/chest.125.5.1843
  • Holloway, A. J., D. S. Diyagama, K. Opeskin, J. Creaney, B. W. Robinson, R. A. Lake, and D. D. Bowtell. 2006. A molecular diagnostic test for distinguishing lung adenocarcinoma from malignant mesothelioma using cells collected from pleural effusions. Clinical Cancer Research 12:5129–35. doi:10.1158/1078-0432.CCR-06-1027
  • Husain, A. N., T. Colby, N. Ordonez, T. Krausz, R. Attanoos, M. B. Beasley, A. C. Borczuk, K. Butnor, P. T. Cagle, L. R. Chirieac, A. Churg, S. Dacic, A. Fraire, F. Galateau-Salle, A. Gibbs, A. Gown, S. Hammar, L. Litzky, A. M. Marchevsky, A. Nicholson, V. Roggli, W. D. Travis, and M. Wick. 2013. Guidelines for pathologic diagnosis of malignant mesothelioma: 2012 Update of the consensus statement from the International Mesothelioma Interest Group. Archives of Pathology & Laboratory Medicine 137:647–67. doi:10.5858/arpa.2012-0214-OA
  • Hwang, H. C., B. S. Sheffield, S. Rodriguez, K. Thompson, C. H. Tse, A. M. Gown, and A. Churg. 2015. Utility of BAP1 Immunohistochemistry and p16 (CDKN2A) FISH in the diagnosis of malignant mesothelioma in effusion cytology specimens. American Journal of Surgical Pathology 40:120–26. doi:10.1097/PAS.0000000000000529
  • IARC. 2002. Man-made vitreous fibres. IARC monographs on the valuation of carcinogenic risks to humans, vo. 81. Lyon, France: IARC Press.
  • IARC. 2012. Arsenic, metals, fibres, and dusts. A review of human carcinogens IARC monographs on the evaluation of carcinogenic risks to humans, vol. 100C. Lyon, France: IARC Press.
  • Jasani, B., and A. Gibbs. 2012. Mesothelioma not associated with asbestos exposure. Archives of Pathology & Laboratory Medicine 136:262–67. doi:10.5858/arpa.2011-0039-RA
  • Jaurand, M. C. 2015. Health effects of carbon nanotubes and some comparisons with natural mineral nanotubes. In Natural mineral nanotubes. Properties and applications, ed. P. Pooria Pasbakhsh, and G. Jock Churchman, 461–480. Oakville, ON, Canada: Apple Academic Press.
  • Jaurand, M. C. In press. Safety of tubular clay minerals: An overview. In Nanosized tubular clay minerals, ed. P. Yuan, A. Thill, and F. Bergaya, 485–508. Elsevier.
  • Jaurand, M. C., and D. Jean. 2016. Biomolecular pathways and malignant pleural mesothelioma. In Malignant pleural mesothelioma: Present status and future directions, ed. T. C. Mineo, 173–196. Sharjah, UAE: Bentham Science Publishers.
  • Jean, D., J. Daubriac, F. Le Pimpec-Barthes, F. Galateau-Salle, and M. C. Jaurand. 2012. Molecular changes in mesothelioma with an impact on prognosis and treatment. Archives of Pathology & Laboratory Medicine 136:277–93. doi:10.5858/arpa.2011-0215-RA
  • Jean, D., E. Thomas, A. Renier, A. De Reynies, C. Lecomte, P. Andujar, J. Fleury-Feith, M. Giovannini, J. Zucman-Rossi, M. H. Stern, and M. C. Jaurand. 2011. Syntenic relationships between genomic profiles of fiber-induced murine and human malignant mesothelioma. American Journal of Pathology 176:881–94. doi:10.1016/j.ajpath.2010.10.039
  • Kameda, T., K. Takahashi, R. Kim, Y. Jiang, M. Movahed, E. K. Park, and J. Rantanen. 2014. Asbestos: Use, bans and disease burden in Europe. Bulletin of the World Health Organization 92:790–97. doi:10.2471/BLT.13.132118
  • Kanarek, M. S. 2011. Mesothelioma from chrysotile asbestos: Update. Annals of Epidemiology 21:688–97. doi:10.1016/j.annepidem.2011.05.010
  • Kang, H. C., H. K. Kim, S. Lee, P. Mendez, J. W. Kim, G. Woodard, J. H. Yoon, K. Y. Jen, L. T. Fang, K. Jones, D. M. Jablons, and I. J. Kim. 2016. Whole exome and targeted deep sequencing identify genome-wide allelic loss and frequent SETDB1 mutations in malignant pleural mesotheliomas. Oncotarget. 7:8321–31.
  • Kao, S. C., M. Fulham, K. Wong, W. Cooper, H. Brahmbhatt, J. MacDiarmid, S. Pattison, J. O. Sagong, Y. Huynh, F. Leslie, N. Pavlakis, S. Clarke, M. Boyer, G. Reid, and N. vanZandwijk. 2015. A significant metabolic and radiological response after a novel targeted microRNA-based treatment approach in malignant pleural mesothelioma. American Journal of Respiratory and Critical Care Medicine 191:1467–69. doi:10.1164/rccm.201503-0461LE
  • Kayat, J., V. Gajbhiye, R. K. Tekade, and N. K. Jain. 2011. Pulmonary toxicity of carbon nanotubes: A systematic report. Nanomedicine 7:40–49.
  • Kirschner, M. B., Y. Y. Cheng, N. J. Armstrong, R. C. Lin, S. C. Kao, A. Linton, S. Klebe, B. C. McCaughan, N. Van Zandwijk, and G. Reid. 2015. MiR-score: A novel 6-microRNA signature that predicts survival outcomes in patients with malignant pleural mesothelioma. Molecular Oncology 9:715–26. doi:10.1016/j.molonc.2014.11.007
  • Klorin, G., E. Rozenblum, O. Glebov, R. L. Walker, Y. Park, P. S. Meltzer, I. R. Kirsch, F. J. Kaye, and A. V. Roschke. 2013. Integrated high-resolution array CGH and SKY analysis of homozygous deletions and other genomic alterations present in malignant mesothelioma cell lines. Cancer Genetics 206:191–205. doi:10.1016/j.cancergen.2013.04.006
  • Kodavanti, U. P., D. Andrews, M. C. Schladweiler, S. H. Gavett, D. E. Dodd, and J. M. Cyphert. 2014. Early and delayed effects of naturally occurring asbestos on serum biomarkers of inflammation and metabolism. Journal of Toxicology and Environmental Health, Part A 77:1024–39. doi:10.1080/15287394.2014.899171
  • Kurumatani, N., and S. Kumagai. 2008. Mapping the risk of mesothelioma due to neighborhood asbestos exposure. American Journal of Respiratory and Critical Care Medicine 178:624–29. doi:10.1164/rccm.200801-063OC
  • Lacourt, A., C. Gramond, S. Audignon, S. Ducamp, J. Fevotte, A. G. Soit Ilg, M. Goldberg, E. Imbernon, and P. Brochard. 2013. Pleural mesothelioma and occupational coexposure to asbestos, mineral wool, and silica. American Journal of Respiratory and Critical Care Medicine 187:977–82. doi:10.1164/rccm.201210-1911OC
  • Lacourt, A., M. Rinaldo, C. Gramond, S. Ducamp, A. Gilg Soit Ilg, M. Goldberg, J. C. Pairon, and P. Brochard. 2014. Co-exposure to refractory ceramic fibres and asbestos and risk of pleural mesothelioma. European Respiratory Journal 44:725–33. doi:10.1183/09031936.00079814
  • Lambert, C. S., B. H. Alexander, G. Ramachandran, R. F. MacLehose, H. H. Nelson, A. D. Ryan, and J. H. Mandel. 2016. A case-control study of mesothelioma in Minnseota iron ore (taconite) miners. Occupational and Environmental Medicine 743:103–9.
  • Langevin, S. M., M. H. O’Sullivan, J. L. Valerio, M. Pawlita, K. M. Applebaum, M. Eliot, M. D. McClean, and K. T. Kelsey. 2013. Occupational asbestos exposure is associated with pharyngeal squamous cell carcinoma in men from the greater Boston area. Occupational and Environmental Medicine 70:858–63. doi:10.1136/oemed-2013-101528
  • Lecouvet, B. 2015. Some further industrial, environmental and biomedical applications of halloysite nanotubes. In Natural mineral nanotubes. Properties and applications, ed. P. P. Pasbakhsh, and P. G. J. Churchman, 383–406. Oakville, ON, Canada: Apple Academic Press.
  • Li, B., S. P. Tang, and K. Z. Wang. 2015. Esophagus cancer and occupational exposure to asbestos: Results from a meta-analysis of epidemiology studies. Diseases of the Esophagus. doi:10.1111/dote.12341.
  • Lim, C. B., C. M. Prele, H. M. Cheah, Y. Y. Cheng, S. Klebe, G. Reid, D. N. Watkins, S. Baltic, P. J. Thompson, and S. E. Mutsaers. 2013. Mutational analysis of hedgehog signaling pathway genes in human malignant mesothelioma. PLoS ONE 8:e66685. doi:10.1371/journal.pone.0066685
  • Lippmann, M. 2014. Toxicological and epidemiological studies on effects of airborne fibers: Coherence and public [corrected] health implications. Critical Reviews in Toxicology 44:643–95. doi:10.3109/10408444.2014.928266
  • Lo Iacono, M., V. Monica, L. Righi, F. Grosso, R. Libener, S. Vatrano, P. Bironzo, S. Novello, L. Musmeci, M. Volante, M. Papotti, and G. V. Scagliotti. 2015. Targeted next-generation sequencing of cancer genes in advanced stage malignant pleural mesothelioma: A retrospective study. Journal of Thoracic Oncology 10:492–99. doi:10.1097/JTO.0000000000000436
  • Lockey, J., G. Lemsters, C. Rice, K. Hansen, L. Levin, R. Shipley, H. Spitz, and J. Wiot. 1996. Refractory ceramic fiber exposure and pleural plaques. American Journal of Respiratory and Critical Care Medicine 154:1405–10. doi:10.1164/ajrccm.154.5.8912756
  • Lockey, J. E., G. K. LeMasters, L. Levin, C. Rice, J. Yiin, S. Reutman, and D. Papes. 2002. A longitudinal study of chest radiographic changes of workers in the refractory ceramic fiber industry. Chest 121:2044–51. doi:10.1378/chest.121.6.2044
  • Lopez-Rios, F., S. Chuai, R. Flores, S. Shimizu, T. Ohno, K. Wakahara, P. B. Illei, S. Hussain, L. Krug, M. F. Zakowski, V. Rusch, A. B. Olshen, and M. Ladanyi. 2006. Global gene expression profiling of pleural mesotheliomas: Overexpression of aurora kinases and P16/CDKN2A deletion as prognostic factors and critical evaluation of microarray-based prognostic prediction. Cancer Research 66:2970–79. doi:10.1158/0008-5472.CAN-05-3907
  • Maisanaba, S., S. Pichardo, M. Puerto, D. Gutierrez-Praena, A. M. Camean, and A. Jos. 2015. Toxicological evaluation of clay minerals and derived nanocomposites: A review. Environmental Research 138:233–54. doi:10.1016/j.envres.2014.12.024
  • Matsumoto, S., K. Nabeshima, M. Hamasaki, T. Shibuta, and T. Umemura. 2014. Upregulation of microRNA-31 associates with a poor prognosis of malignant pleural mesothelioma with sarcomatoid component. Medical Oncology 31:303. doi:10.1007/s12032-014-0303-2
  • Melaiu, O., E. Bracci, A. Cristaudo, A. Bonotti, R. Foddis, L. Mutti, F. Gemignani, and S. Landi. 2013. Comparative genomic hybridization studies on mesothelioma show a parallel fate of 1p21-1p22 and 9p21 bands and a chromosomally stable sub-group. American Journal of Medical and Biological Research 1:149–58. doi:10.12691/ajmbr-1-4-8
  • Melaiu, O., A. Cristaudo, E. Melissari, M. Di Russo, A. Bonotti, R. Bruno, R. Foddis, F. Gemignani, S. Pellegrini, and S. Landi. 2012. A review of transcriptome studies combined with data mining reveals novel potential markers of malignant pleural mesothelioma. Mutation Research/Reviews in Mutation Research 750:132–40. doi:10.1016/j.mrrev.2011.12.003
  • Melaiu, O., E. Melissari, L. Mutti, E. Bracci, C. De Santi, C. Iofrida, M. Di Russo, A. Cristaudo, A. Bonotti, M. Cipollini, S. I. Garritano, R. Foddis, M. Lucchi, S. Pellegrini, F. Gemignani, and S. Landi. 2015. Expression status of candidate genes in mesothelioma tissues and cell lines. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 771:6–12. doi:10.1016/j.mrfmmm.2014.11.002
  • Menvielle, G., A. Fayosse, L. Radoi, F. Guida, M. Sanchez, M. Carton, D. Cyr, A. Schmaus, S. Cenee, J. Fevotte, P. Delafosse, I. Stucker, and D. Luce. 2016. The joint effect of asbestos exposure, tobacco smoking and alcohol drinking on laryngeal cancer risk: Evidence from the French population-based case-control study, ICARE. Occupational and Environmental Medicine 73:28–33.
  • Mezzapelle, R., U. Miglio, O. Rena, A. Paganotti, S. Allegrini, J. Antona, F. Molinari, M. Frattini, G. Monga, O. Alabiso, and R. Boldorini. 2013. Mutation analysis of the EGFR gene and downstream signalling pathway in histologic samples of malignant pleural mesothelioma. British Journal of Cancer 108:1743–49. doi:10.1038/bjc.2013.130
  • Miyanaga, A., M. Masuda, K. Tsuta, K. Kawasaki, Y. Nakamura, T. Sakuma, H. Asamura, A. Gemma, and T. Yamada. 2015. Hippo pathway gene mutations in malignant mesothelioma: Revealed by RNA and targeted exon sequencing Journal of Thoracic Oncology 10:844–51. doi:10.1097/JTO.0000000000000493
  • Mossman, B. T., M. Lippmann, T. W. Hesterberg, K. T. Kelsey, A. Barchowsky, and J. C. Bonner 2011. Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos. Journal of Toxicology and Environmental Health, Part B 14:76–121. doi:10.1080/10937404.2011.556047
  • Murakami, H., T. Mizuno, T. Taniguchi, M. Fujii, F. Ishiguro, T. Fukui, S. Akatsuka, Y. Horio, T. Hida, Y. Kondo, S. Toyokuni, H. Osada, and Y. Sekido. 2011. LATS2 is a tumor suppressor gene of malignant mesothelioma. Cancer Research 71:873–83. doi:10.1158/0008-5472.CAN-10-2164
  • Murali, R., T. Wiesner, and R. A. Scolyer. 2013. Tumours associated with BAP1 mutations. Pathology 45:116–26. doi:10.1097/PAT.0b013e32835d0efb
  • Musk, A. W., N. Olsen, H. Alfonso, A. Reid, R. Mina, P. Franklin, J. Sleith, N. Hammond, T. Threlfall, K. B. Shilkin, and N. H. de Klerk. 2011. Predicting survival in malignant mesothelioma. European Respiratory Journal 38:1420–24. doi:10.1183/09031936.00000811
  • Nasu, M., M. Emi, S. Pastorino, M. Tanji, A. Powers, H. Luk, F. Baumann, Y. A. Zhang, A. Gazdar, S. Kanodia, M. Tiirikainen, E. Flores, G. Gaudino, M. J. Becich, H. I. Pass, H. Yang, and M. Carbone. 2015. High incidence of somatic BAP1 alterations in sporadic malignant mesothelioma. Journal of Thoracic Oncology 10:565–76. doi:10.1097/JTO.0000000000000471
  • NIOSH. 2011. Asbestos fibers and other elongate mineral particles: State of the science and roadmap for research. Revised April 2011. Current Intelligence Bulletin 62:1–153.
  • Oberdorster, G., V. Castranova, B. Asgharian, and P. Sayre. 2015. Inhalation exposure to carbon nanotubes (CNT) and carbon nanofibers (CNF): Methodology and dosimetry. Journal of Toxicology and Environmental Health, Part B 18:121–212. doi:10.1080/10937404.2015.1051611
  • Offermans, N. S., R. Vermeulen, A. Burdorf, R. A. Goldbohm, T. Kauppinen, H. Kromhout, and P. A. Van Den Brandt. 2014a. Occupational asbestos exposure and risk of pleural mesothelioma, lung cancer, and laryngeal cancer in the prospective Netherlands cohort study. Journal of Occupational and Environmental Medicine 56:6–19. doi:10.1097/JOM.0000000000000060
  • Offermans, N. S., R. Vermeulen, A. Burdorf, R. A. Goldbohm, A. P. Keszei, S. Peters, T. Kauppinen, H. Kromhout, and P. A. Van Den Brandt. 2014b. Occupational asbestos exposure and risk of esophageal, gastric and colorectal cancer in the prospective Netherlands cohort study. International Journal of Cancer 135:1970–77. doi:10.1002/ijc.28817
  • Ortega-Guerrero, M. A., G. Carrasco-Nunez, H. Barragan-Campos, and M. R. Ortega. 2015. High incidence of lung cancer and malignant mesothelioma linked to erionite fibre exposure in a rural community in Central Mexico. Occupational and Environmental Medicine 72:216–18. doi:10.1136/oemed-2013-101957
  • Pairon, J. C., P. Andujar, M. Rinaldo, J. Ameille, P. Brochard, S. Chamming’s, B. Clin, G. Ferretti, A. Gislard, F. Laurent, A. Luc, P. Wild, and C. Paris. 2014. Asbestos exposure, pleural plaques, and the risk of death from lung cancer. American Journal of Respiratory and Critical Care Medicine 190:1413–20. doi:10.1164/rccm.201406-1074OC
  • Pairon, J. C., F. Laurent, M. Rinaldo, B. Clin, P. Andujar, J. Ameille, P. Brochard, S. Chammings, G. Ferretti, F. Galateau-Salle, A. Gislard, M. Letourneux, A. Luc, E. Schorle, and C. Paris. 2013. Pleural plaques and the risk of pleural mesothelioma. Journal of the National Cancer Institute 105:293–301. doi:10.1093/jnci/djs513
  • Panagopoulos, I., J. Thorsen, L. Gorunova, F. Micci, L. Haugom, B. Davidson, and S. Heim. 2013. RNA sequencing identifies fusion of the EWSR1 and YY1 genes in mesothelioma with t(14;22)(q32;q12). Genes Chromosomes and Cancer 52:733–40. doi:10.1002/gcc.22068
  • Panou, V., M. Vyberg, U. M. Weinreich, C. Meristoudis, U. G. Falkmer, and O. D. Roe. 2015. The established and future biomarkers of malignant pleural mesothelioma. Cancer Treatment Reviews 41:486–95. doi:10.1016/j.ctrv.2015.05.001
  • Pasdar, E. A., M. Smits, M. Stapelberg, M. Bajzikova, M. Stantic, J. Goodwin, B. Yan, J. Stursa, J. Kovarova, K. Sachaphibulkij, A. Bezawork-Geleta, M. Sobol, A. Filimonenko, M. Tomasetti, R. Zobalova, P. Hozak, L. F. Dong, and J. Neuzil. 2015. Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS ONE 10:e0119549. doi:10.1371/journal.pone.0119549
  • Pass, H. I., C. Goparaju, S. Ivanov, J. Donington, M. Carbone, M. Hoshen, D. Cohen, A. Chajut, S. Rosenwald, H. Dan, S. Benjamin, and R. Aharonov. 2010. Hsa-miR-29c* is linked to the prognosis of malignant pleural mesothelioma. Cancer Research 70:1916–24. doi:10.1158/0008-5472.CAN-09-3993
  • Pass, H. I., Z. Liu, A. Wali, R. Bueno, S. Land, D. Lott, F. Siddiq, F. Lonardo, M. Carbone, and S. Draghici. 2004. Gene expression profiles predict survival and progression of pleural mesothelioma. Clinical Cancer Research 10:849–59. doi:10.1158/1078-0432.CCR-0607-3
  • Peters, G. J., A. Avan, M. G. Ruiz, V. Orsini, A. Avan, E. Giovannetti, and E. F. Smit. 2014. Predictive role of repair enzymes in the efficacy of cisplatin combinations in pancreatic and lung cancer. Anticancer Research 34:435–42.
  • Petrilli, A. M., and C. Fernandez-Valle. 2015. Role of merlin/NF2 inactivation in tumor biology. Oncogene 35:537–48. doi:10.1038/onc.2015.125
  • Pintos, J., M. E. Parent, B. W. Case, M. C. Rousseau, and J. Siemiatycki. 2009. Risk of mesothelioma and occupational exposure to asbestos and man-made vitreous fibers: Evidence from two case-control studies in Montreal, Canada. Journal of Occupational and Environmental Medicine 51:1177–84. doi:10.1097/JOM.0b013e3181b68cef
  • Pohl, S., R. Scott, F. Arfuso, V. Perumal, and A. Dharmarajan. 2015. Secreted frizzled-related protein 4 and its implications in cancer and apoptosis. Tumor Biology 36:143–52. doi:10.1007/s13277-014-2956-z
  • Pukkala, E., J. I. Martinsen, E. Weiderpass, K. Kjaerheim, E. Lynge, L. Tryggvadottir, P. Sparen, and P. A. Demers. 2014. Cancer incidence among firefighters: 45 Years of follow-up in five Nordic countries. Occupational and Environmental Medicine 71:398–404. doi:10.1136/oemed-2013-101803
  • Rake, C., C. Gilham, J. Hatch, A. Darnton, J. Hodgson, and J. Peto. 2009. Occupational, domestic and environmental mesothelioma risks in the British population: A case-control study. British Journal of Cancer 100:1175–83. doi:10.1038/sj.bjc.6604879
  • Rapisarda, V., C. Ledda, V. Ricceri, F. Arena, A. Musumeci, A. Marconi, L. Fago, M. Bracci, L. Santarelli, and M. Ferrante. 2015. Detection of pleural plaques in workers exposed to inhalation of natural fluoro-edenite fibres. Oncology Letters 9:2046–52.
  • Reid, A., P. Franklin, N. Olsen, J. Sleith, L. Samuel, P. Aboagye-Sarfo, N. De Klerk, and A. W. Musk. 2013. All-cause mortality and cancer incidence among adults exposed to blue asbestos during childhood. American Journal of Industrial Medicine 56:133–45. doi:10.1002/ajim.v56.2
  • Reid, G. 2015. MicroRNAs in mesothelioma: From tumour suppressors and biomarkers to therapeutic targets. Journal of Thoracic Disease 7:1031–40.
  • Robinson, B. W., A. W. Musk, and R. A. Lake. 2005. Malignant mesothelioma. Lancet 366:397–408. doi:10.1016/S0140-6736(05)67025-0
  • Rodelsperger, K., K. H. Jockel, H. Pohlabeln, W. Romer, and H. J. Woitowitz. 2001. Asbestos and man-made vitreous fibers as risk factors for diffuse malignant mesothelioma: Results from a German hospital-based case-control study. American Journal of Industrial Medicine 39:262–75. doi:10.1002/1097-0274(200103)39:3<262::AID-AJIM1014>3.0.CO;2-R
  • Rolland, P., C. Gramond, A. Lacourt, P. Astoul, S. Chamming’s, S. Ducamp, C. Frenay, F. Galateau-Salle, A. G. Ilg, E. Imbernon, N. Le Stang, J. C. Pairon, M. Goldberg, and P. Brochard. 2010. Occupations and industries in France at high risk for pleural mesothelioma: A population-based case-control study (1998–2002). American Journal of Industrial Medicine 53:1207–19. doi:10.1002/ajim.20895
  • Rusch, A., G. Ziltener, K. Nackaerts, W. Weder, R. A. Stahel, and E. Felley-Bosco. 2015. Prevalence of BRCA-1 associated protein 1 germline mutation in sporadic malignant pleural mesothelioma cases. Lung Cancer 87:77–79. doi:10.1016/j.lungcan.2014.10.017
  • Scherpereel, A., P. Astoul, P. Baas, T. Berghmans, H. Clayson, P. De Vuyst, H. Dienemann, F. Galateau-Salle, C. Hennequin, G. Hillerdal, C. Le Pechoux, L. Mutti, J. C. Pairon, R. Stahel, P. Van Houtte, J. Van Meerbeeck, D. Waller, and W. Weder. 2010. Guidelines of the European Respiratory Society and the European Society of Thoracic Surgeons for the management of malignant pleural mesothelioma. European Respiratory Journal 35:479–95. doi:10.1183/09031936.00063109
  • Schildgen, V., O. Pabst, R. L. Tillmann, J. Lusebrink, O. Schildgen, C. Ludwig, M. Brockmann, and E. Stoelben. 2015. Low frequency of EGFR mutations in pleural mesothelioma patients, Cologne, Germany. Applied Immunohistochemistry & Molecular Morphology 23:118–25. doi:10.1097/PDM.0b013e3182a3645e
  • Schreiber, N., M. Strobele, R. Hochscheid, E. Kotte, P. Weber, H. Bockhorn, and B. Muller. 2016. Modifications of carbon black nanoparticle surfaces modulate type II pneumocyte homeostasis. Journal of Toxicology and Environmental Health. Part A 79:153–64.
  • Sebastien, P., A. Fondimare, J. Bignon, G. Monchaux, J. Desbordes, and G. Bonnaud. 1975. Topographic distribution of asbestos fibres in human lung in relation to occupational and non-occupational exposure. Inhaled Particles 4:435–46.
  • Sekido, Y. 2010. Genomic abnormalities and signal transduction dysregulation in malignant mesothelioma cells. Cancer Science 101:1–6. doi:10.1111/cas.2009.101.issue-1
  • Sekido, Y. 2013. Molecular pathogenesis of malignant mesothelioma. Carcinogenesis 34:1413–19. doi:10.1093/carcin/bgt166
  • Selikoff, I. J., J. Churg, and E. C. Hammond. 1964. Asbestos exposure and neoplasia. Journal of the American Medical Association 188:22–26. doi:10.1001/jama.1964.03060270028006
  • Shukuya, T., M. Serizawa, M. Watanabe, H. Akamatsu, M. Abe, H. Imai, T. Tokito, A. Ono, T. Taira, H. Kenmotsu, T. Naito, H. Murakami, T. Takahashi, M. Endo, Y. Ohde, T. Nakajima, N. Yamamoto, and Y. Koh. 2014. Identification of actionable mutations in malignant pleural mesothelioma. Lung Cancer 86:35–40. doi:10.1016/j.lungcan.2014.08.004
  • Shvedova, A. A., E. R. Kisin, D. Porter, P. Schulte, V. E. Kagan, B. Fadeel, and V. Castranova. 2009. Mechanisms of pulmonary toxicity and medical applications of carbon nanotubes: Two faces of Janus? Pharmacology & Therapeutics 121:192–204. doi:10.1016/j.pharmthera.2008.10.009
  • Shvedova, A. A., N. Yanamala, E. R. Kisin, T. O. Khailullin, M. E. Birch, and L. M. Fatkhutdinova. 2016. Integrated analysis of dysregulated ncRNA and mRNA expression profiles in humans exposed to carbon nanotubes. PLoS ONE 11:e0150628. doi:10.1371/journal.pone.0150628
  • Simson, F. W. 1928. Pulmonary asbestosis in South Africa. British Medical Journal 1:885–87. doi:10.1136/bmj.1.3516.885
  • Spirtas, R., E. F. Heineman, L. Bernstein, G. W. Beebe, R. J. Keehn, A. Stark, B. L. Harlow, and J. Benichou. 1994. Malignant mesothelioma: Attributable risk of asbestos exposure. Occupational and Environmental Medicine 51:804–11. doi:10.1136/oem.51.12.804
  • Stayner, L., L. S. Welch, and R. Lemen. 2013. The worldwide pandemic of asbestos-related diseases. Annual Review of Public Health 34:205–16. doi:10.1146/annurev-publhealth-031811-124704
  • Suraokar, M. B., M. I. Nunez, L. Diao, C. W. Chow, D. Kim, C. Behrens, H. Lin, S. Lee, G. Raso, C. Moran, D. Rice, R. Mehran, J. J. Lee, H. I. Pass, J. Wang, A. A. Momin, B. P. James, A. Corvalan, K. Coombes, A. Tsao, and I. I. Wistuba 2014. Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications. Annals of Oncology 25:1184–92. doi:10.1093/annonc/mdu127
  • Tallet, A., J. C. Nault, A. Renier, I. Hysi, F. Galateau-Salle, A. Cazes, M. C. Copin, P. Hofman, P. Andujar, F. Le Pimpec-Barthes, J. Zucman-Rossi, M. C. Jaurand, and D. Jean. 2014. Overexpression and promoter mutation of the TERT gene in malignant pleural mesothelioma. Oncogene 33:3748–52. doi:10.1038/onc.2013.351
  • Tarres, J., C. Alberti, X. Martinez-Artes, R. Abos-Herrandiz, M. Rosell-Murphy, I. Garcia-Allas, I. Krier, G. Cantarell, M. Gallego, J. Canela-Soler, and R. Orriols. 2013. Pleural mesothelioma in relation to meteorological conditions and residential distance from an industrial source of asbestos. Occupational and Environmental Medicine 70:588–90. doi:10.1136/oemed-2012-101198
  • Testa, J. R., M. Cheung, J. Pei, J. E. Below, Y. Tan, E. Sementino, N. J. Cox, A. U. Dogan, H. I. Pass, S. Trusa, M. Hesdorffer, M. Nasu, A. Powers, Z. Rivera, S. Comertpay, M. Tanji, G. Gaudino, H. Yang, and M. Carbone. 2011. Germline BAP1 mutations predispose to malignant mesothelioma. Nature Genetics 43:1022–25. doi:10.1038/ng.912
  • Thies, S., M. Friess, L. Frischknecht, D. Korol, E. Felley-Bosco, R. Stahel, B. Vrugt, W. Weder, I. Opitz, and A. Soltermann. 2015. Expression of the stem cell factor nestin in malignant pleural mesothelioma is associated with poor prognosis. PLoS ONE 10:e0139312. doi:10.1371/journal.pone.0139312
  • Thurneysen, C., I. Opitz, S. Kurtz, W. Weder, R. A. Stahel, and E. Felley-Bosco. 2009. Functional inactivation of NF2/merlin in human mesothelioma. Lung Cancer 64:140–47. doi:10.1016/j.lungcan.2008.08.014
  • Toumpanakis, D., and S. E. Theocharis. 2011. DNA repair systems in malignant mesothelioma. Cancer Letters 312:143–49. doi:10.1016/j.canlet.2011.08.021
  • Tran, C. L., R. Trantra, K. Donaldson, V. Stone, S. M. Hankin, B. Ross, R. J. Aitknen, and A. D. Jones. 2011. A hypothetical model for predicting the toxicity of high aspect ratio nanoparticles (HARN). Journal of Nanoparticle Research 13:6683–98. doi:10.1007/s11051-011-0575-9
  • Tran, P. A., L. Zhang, and T. J. Webster. 2009. Carbon nanofibers and carbon nanotubes in regenerative medicine. Advanced Drug Delivery Reviews 61:1097–114. doi:10.1016/j.addr.2009.07.010
  • Ueno, T., S. Toyooka, T. Fukazawa, T. Kubo, J. Soh, H. Asano, T. Muraoka, N. Tanaka, Y. Maki, K. Shien, M. Furukawa, M. Sakaguchi, H. Yamamoto, K. Tsukuda, and S. Miyoshi. 2014. Preclinical evaluation of microRNA-34b/c delivery for malignant pleural mesothelioma. Acta Medica Okayama 68:23–26.
  • Upadhyayula, V. K., S. Deng, M. C. Mitchell, and G. B. Smith. 2009. Application of carbon nanotube technology for removal of contaminants in drinking water: A review. Science of the Total Environment 408:1–13. doi:10.1016/j.scitotenv.2009.09.027
  • Vahedi, V., and P. Pasbakhsh. 2015. Applications of natural mineral nanotubes in nanocomposites. In Natural mineral nanotubes. Properties and applications, ed. P. P. Pasbakhsh, and P. G. J. Churchman, 141–172. Oakville, ON, Canada: Apple Academic Press.
  • van der Bij, S., H. Koffijberg, V. Lenters, L. Portengen, K. G. Moons, D. Heederik, and R. C. Vermeulen. 2013. Lung cancer risk at low cumulative asbestos exposure: Meta-regression of the exposure-response relationship. Cancer, Causes and Control 24:1–12. doi:10.1007/s10552-012-0107-7
  • Vandermeers, F., S. Neelature Sriramareddy, C. Costa, R. Hubaux, J. P. Cosse, and L. Willems. 2013. The role of epigenetics in malignant pleural mesothelioma. Lung Cancer 81:311–18. doi:10.1016/j.lungcan.2013.05.014
  • Wagner, J. C., C. A. Sleggs, and P. Marchand. 1960. Diffuse pleural mesothelioma and asbestos exposure in the North Western Cape Province. British Journal of Industrial Medicine 17:260–71.
  • Wylie, A. G., and P. A. Candela. 2015. Methodologies for determining the sources, characteristics, distribution and abundance of asbestiform and nonasbestestiform amphibole and serpentine in ambient air and water. Journal of Toxicology and Environmental Health, Part B 18:1–42 doi:10.1080/10937404.2014.997945
  • Xio, S., D. Li, J. Vijg, D. J. Sugarbaker, J. M. Corson, and J. A. Fletcher. 1995. Codeletion of p15 and p16 in primary malignant mesothelioma. Oncogene 11:511–15.
  • Xu, J., Y. Kadariya, M. Cheung, J. Pei, J. Talarchek, E. Sementino, Y. Tan, C. W. Menges, K. Q. Cai, S. Litwin, H. Peng, J. Karar, F. J. Rauscher, and J. R. Testa. 2014. Germline mutation of Bap1 accelerates development of asbestos-induced malignant mesothelioma. Cancer Research 74:4388–97. doi:10.1158/0008-5472.CAN-14-1328
  • Yoshikawa, Y., A. Sato, T. Tsujimura, M. Emi, T. Morinaga, K. Fukuoka, S. Yamada, A. Murakami, N. Kondo, S. Matsumoto, Y. Okumura, F. Tanaka, S. Hasegawa, T. Nakano, and T. Hashimoto-Tamaoki. 2012. Frequent inactivation of the BAP1 gene in epithelioid-type malignant mesothelioma. Cancer Science 103:868–74. doi:10.1111/cas.2012.103.issue-5
  • Zalcman, G., J. Mazieres, J. Margery, L. Greillier, C. Audigier-Valette, D. Moro-Sibilot, O. Molinier, R. Corre, I. Monnet, V. Gounant, F. Riviere, H. Janicot, R. Gervais, C. Locher, B. Milleron, Q. Tran, M. P. Lebitasy, F. Morin, C. Creveuil, J. J. Parienti, and A. Scherpereel, and Intergroup French Cooperative Thoracic. 2016. Bevacizumab for newly diagnosed pleural mesothelioma in the Mesothelioma Avastin Cisplatin Pemetrexed Study (MAPS): A randomised, controlled, open-label, phase 3 trial. Lancet. 387:1405–14.
  • Zauderer, M. G., M. Bott, R. McMillan, C. S. Sima, V. Rusch, L. M. Krug, and M. Ladanyi. 2013. Clinical characteristics of patients with malignant pleural mesothelioma harboring somatic BAP1 mutations. Journal of Thoracic Oncology 8:1430–33. doi:10.1097/JTO.0b013e31829e7ef9.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.