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Journal of Chemotherapy Volume 1, 1989 - Issue 6
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Original Articles

Methylprednisolone versus Metoclopramide as Antiemetic Treatment in Patients Receiving Adjuvant Cyclophosphamide, Methotrexate, 5-Fluorouracil (CMF) Chemotherapy: A randomized crossover blind study.

E. GezDepartment of Oncology, Hadassah University Hospital, Jerusalem, Israel
,
A. SulkesDepartment of Oncology, Hadassah University Hospital, Jerusalem, Israel
,
L. OchayonDepartment of Oncology, Hadassah University Hospital, Jerusalem, Israel
,
C. GeraDepartment of Oncology, Hadassah University Hospital, Jerusalem, Israel
,
S. NathanDepartment of Oncology, Hadassah University Hospital, Jerusalem, Israel
,
Y. CassDepartment of Pharmacy, Sharett Institute, Hadassah University Hospital, Jerusalem, Israel
,
E. RubelloDepartment of Pharmacy, Sharett Institute, Hadassah University Hospital, Jerusalem, Israel
&
S. BiranDepartment of Oncology, Hadassah University Hospital, Jerusalem, Israel
 show all
Pages 365-368 | Published online: 14 Jul 2016

References

  • Morran C, Smith DC, Anderson DA, McArdle CS. Incidence of nausea and vomiting with cytotoxic chemotherapy: a prospective randomised trial of antiemetics. Br Med J 1979; 1: 1323–1324.
  • Wilcox PM, Petting JH, Nettesheim KM, et al. Anticipatory vomiting in women receiving cyclophosphamide, methotrexate and 5-fluorouracil (CMF) adjuvant chemotherapy for breast carcinoma. Cancer Treat Rep 1982; 66: 1601–1604.
  • Gez E, Goodman S, Isacson R, et al. High-dose metoclopramide and dexamethasone as an antiemetic in chemotherapy of breast cancer. Oncology 1986; 43: 173–175.
  • Gez E, Warner-Efratey E, Ben-Yosef R et al. High-dose metoclopramide and dexamethasone as an antiemetic in outpatients receiving chemotherapy for breast cancer: Second study. Oncology 1987; 44: 237–239.
  • Chiara S, Scarsi P, Campora E et al. Low-dose metoclopramide versus methylprednisolone in controlling chemother apy-induced nausea and vomiting. Chemioterapia 1984; 3: 333–336.
  • Campora E, Chiara S, Bruzzi P et al. The antiemetic efficacy of methylprednisone compared with metoclopramide in outpatients receiving adjuvant CMF chemotherapy for breast cancer: A randomized trial. Tumori 1985; 71: 459–462.
  • Roila F, Basurto C, Minotti V et al. Methylprednisolone versus metoclopramide for prevention of nausea and vomiting in breast cancer patients treated with intravenous cyclophos phamide, methotrexate and 5-fluorouracil: A double-blind randomized study. Oncology 1988; 45:346–349.
  • Bennet AE, Richi AE. Questionnaires in medicine: A guide to their design and use. Oxford University Press, 1975.
  • Chiara S, Campora E, Lionetto R, et al. Methylprednisolone for the control of CMF-induced emesis. Am J Clin Oncol 1987; 10: 264–267.

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