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Journal of Chemotherapy Volume 4, 1992 - Issue 2
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Original Articles

Relation of Changes in Hepatitis B Virus Replication Markers to the Outcome of Interferon Treatment in Patients with Chronic Hepatitis

S. NardielloIstituto di Clinica Malattie Infettive, Prima Facoltà di Medicina, Università di Napoli, Italy.
,
M. GargiuloSezione Malattie Infettive, Ospedale Civile di Teramo, Italy.
,
T. PizzellaIstituto di Clinica Malattie Infettive, Prima Facoltà di Medicina, Università di Napoli, Italy.
,
L. DigilioIstituto di Clinica Malattie Infettive, Prima Facoltà di Medicina, Università di Napoli, Italy.
,
L. Di OttavioSezione Malattie Infettive, Ospedale Civile di Teramo, Italy.
&
B. GalantiIstituto di Clinica Malattie Infettive, Prima Facoltà di Medicina, Università di Napoli, Italy.
Pages 95-98 | Published online: 15 Jul 2016

References

  • Davis GL, Hoofnagle JH. Interferon in viral hepatitis: role in pathogenesis and treatment. Hepatology 1986; 6: 1038–1041.
  • Utili R, Sagnelli E, Galanti B, et al. Prolonged treatment of children with chronic hepatitis B with recombinant alpha-2a interferon: a placebo controlled randomized study. Am J Gastroenterol 1991; 86: 327–330.
  • Eddleston A. Interferons in the treatment of chronic hepatitis B virus infection. Med Clin North Am 1986; May suppl: 25–30.
  • Brook MG, Petrovic L, McDonald JA, Schever PJ, Thomas HC. Histological improvement after antiviral treatment for chronic hepatitis B infection. J Hepatol 1989; 8: 218–225.
  • Lieberman HM, LaBrecque DR, Kew MC, Hadziyannis SJ, Shafritz DA. Detection of hepatitis B virus DNA directly in human serum by a simplified molecular hybridization test: comparison to HBeAg/anti-HBe status in HBsAg carriers. Hepatology 1983; 3: 285–291.
  • Hoofnagle JH, Peters M, Mullen KD, et al. Randomized, controlled trial of recombinant human alpha-interferon in patients with chronic hepatitis B. Gastroenterology 1988; 95: 1318–1325.
  • McDonald JA, Caruso L, Karayannis P, Scully LJ, Harris JRW, Forster GE, Thomas HC. Diminished responsiveness of male homosexual chronic hepatitis B virus carriers with HTLV-III antibodies to recombinant alpha-interferon. Hepatology 1987; 7: 719–723.
  • Scullard GH, Pollard RB, Smith JL, Sacks SL, Gregory PB, Robinson WS, Merigan TC. Antiviral treatment of chronic hepatitis B viral infection. Changes in viral markers with inferferon combined with adenine arabinoside. J Infect Dis 1981; 143: 772–782.
  • Perrillo RP, Schifi ER, Davis GL, et al. A randomized, controlled trial of interferon alpha-2b alone and after prednisone withdrawal for the treatment of chronic hepatitis B. N Engl J Med 1990; 323: 295–301.

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