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Brief Communication

Galleria mellonella as a model system to assess the efficacy of antimicrobial agents against Klebsiella pneumoniae infection

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Pages 252-256 | Received 08 Sep 2015, Accepted 17 Feb 2016, Published online: 30 May 2016

References

  • Murphy CN, Clegg S. Klebsiella pneumoniae and type 3 fimbriae: nosocomial infection, regulation and biofilm formation. Future Microbiol. 2012;7(8):991–1002.10.2217/fmb.12.74
  • Desbois AP, Coote PJ. Wax moth larva (Galleria mellonella): an in vivo model for assessing the efficacy of antistaphylococcal agents. J Antimicrob Chemother. 2011;66(8): 1785–90.
  • Hornsey M, Phee L, Longshaw C, Wareham DW. In vivo efficacy of telavancin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection. Int J Antimicrob Agents. 2013;41(3):285–7.10.1016/j.ijantimicag.2012.11.013
  • CLSI. Performance standards for antimicrobial susceptibility testing; Twenty-fouth informational supplement, M100-S24. Wayne, PA: Clinical and Laboraotory Standards Institute; 2014.
  • Peleg AY, Jara S, Monga D, Eliopoulos GM, Moellering Jr RC, Mylonakis E. Galleria mellonella as a model system to study Acinetobacter baumannii pathogenesis and therapeutics. Antimicrob Agents Chemother. 2009;53(6):2605e9.
  • Luther MK, Arvanitis M, Mylonakis E, LaPlante KL. Activity of daptomycin or linezolid in combination with rifampin or gentamicin against biofilm-forming Enterococcus faecalis or E. faecium in an in vitro pharmacodynamic model using simulated endocardial vegetations and an in vivo survival assay using Galleria mellonella larvae. Antimicrob Agents Chemother. 2014;58(8):4612–20.10.1128/AAC.02790-13
  • Yang H, Chen G, Hu L, Liu Y, Cheng J, Li H, et al. In vivo activity of daptomycin/colistin combination therapy in a Galleria mellonella model of Acinetobacter baumannii infection. Int J Antimicrob Agents. 2015;45(2):188–91.10.1016/j.ijantimicag.2014.10.012
  • Mukherjee K, Altincicek B, Hain T, Domann E, Vilcinskas A, Chakraborty T. Galleria mellonella as a model system for studying Listeria pathogenesis. Appl Environ Microbiol 2010;76(1):310e7.
  • Hill L, Veli N, Coote PJ. Evaluation of Galleria mellonella larvae for measuring the efficacy and pharmacokinetics of antibiotic therapies against Pseudomonas aeruginosa infection. Int J Antimicrob Agents. 2014;43(3):254–61.10.1016/j.ijantimicag.2013.11.001
  • Thomas RJ, Hamblin KA, Armstrong SJ, Müller CM, Bokori-Brown M, Goldman S, et al. Galleria mellonella as a model system to test the pharmacokinetics and efficacy of antibiotics against Burkholderia pseudomallei. Int J Antimicrob Agents. 2013;41(4):330–6.10.1016/j.ijantimicag.2012.12.009
  • Betts JW, Phee LM, Woodford N, Wareham DW. Activity of colistin in combination with tigecycline or rifampicin against multidrug-resistant Stenotrophomonas maltophilia. Eur J Clin Microbiol Infect Dis. 2014;33(9):1565–72.10.1007/s10096-014-2101-3
  • Chibebe Junior J, Fuchs BB, Sabino CP, Junqueira JC, Jorge AO, Ribeiro MS, et al. Photodynamic and antibiotic therapy impair the pathogenesis of Enterococcus faecium in a whole animal insect model. PLoS One. 2013;8(2):e5592610.1371/journal.pone.0055926
  • Pereira MF, Rossi CC, de Queiroz MV, Martins GF, Isaac C, Bosse JT, et al. Galleria mellonella is an effective model to study Actinobacillus pleuropneumoniae infection. Microbiology. 2015;161(Pt 2):387–400.10.1099/mic.0.083923-0
  • McLaughlin MM, Advincula MR, Malczynski M, Barajas G, Qi C, Scheetz MH. Quantifying the clinical virulence of Klebsiella pneumoniae producing carbapenemase Klebsiella pneumoniae with a Galleria mellonella model and a pilot study to translate to patient outcomes. BMC Infect Dis. 2014;14:31.10.1186/1471-2334-14-31
  • Wand ME, McCowen JW, Nugent PG, Sutton JM. Complex interactions of Klebsiella pneumoniae with the host immune system in a Galleria mellonella infection model. J Med Microbiol. 2013;62(Pt 12):1790–8.10.1099/jmm.0.063032-0
  • Betts JW, Phee LM, Hornsey M, Woodford N, Wareham DW. In Vitro and In Vivo Activities of Tigecycline-Colistin Combination Therapies against Carbapenem-Resistant Enterobacteriaceae. Antimicrob Agents Chemother. 2014;58(6):3541–6.10.1128/AAC.02449-14

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