References
- World Health Organization. Chagas disease (American trypanosomiasis). WHO, Geneva, 2012, Fact sheet No. 340.
- McKerrow JH, Doyle PS, Engel JC, Podust LM, Robertson SA, Ferreira R, et al. Two approaches to discovering and developing new drugs for Chagas disease. Mem Inst Oswaldo Cruz. 2009;104(1):263–9.10.1590/S0074-02762009000900034
- Piacenza L, Peluffo G, Alvarez MN, Martínez A, Radi R. Trypanosoma cruzi antioxidant enzymes as virulence factors in Chagas disease. Antioxid Redox Signal. 2013;19(7):723–34.10.1089/ars.2012.4618
- Cussó O, Garcia-Bosch I, Ribas X, Lloret-Fillol J, Costas M. Asymmetric epoxidation with H2O2 by manipulating the electronic properties of non-heme iron catalysts. J Am Chem Soc. 2013;135:14871–8.10.1021/ja4078446
- Garcia-Bosch I, Gómez L, Polo A, Ribas X, Costas M. Stereoselective epoxidation of alkenes with hydrogen peroxide using a bipyrrolidine-based family of manganese complexes. Adv Synth Catal. 2012;354:65–70.10.1002/adsc.201100409
- Company A, Prat I, Frisch JR, Mas-Ballesté R, Güell M, Juhász G, et al. Modeling the cis-oxo-labile binding site motif of non-heme iron oxygenases: water exchange and oxidation reactivity of a non-heme iron(IV)-oxo compound bearing a tripodal tetradentate ligand. Chem Eur J. 2011;17:1622–34.10.1002/chem.v17.5
- Company A, Gómez L, Fontrodona X, Ribas X, Costas M. A novel platform for modeling oxidative catalysis in non-heme iron oxygenases with unprecedented efficiency. Chem Eur J. 2008;14:5727–31.10.1002/chem.v14:19
- Garcia-Bosch I, Company A, Fontrodona X, Ribas X, Costas M. Efficient and selective peracetic acid epoxidation catalyzed by a robust manganese catalyst. Org Lett. 2008;10:2095–8.10.1021/ol800329m
- Wieghardt K, Schoeffmann E, Nuber B, Weiss J. Syntheses, properties and electrochemistry of transition-metal complexes of the macrocycle 1,4,7-tris(2-pyridylmethyl)-1,4,7-triazacyclononane (L). Crystal structures of [NiL](ClO4)2, [MnL](ClO4)2, and [PdL](PF6)2 containing a distorted-square-base-pyramidal PdIIN5 core. Inorg Chem. 1986;25:4877–83.10.1021/ic00247a020
- Olmo F, Marín C, Clares MP, Blasco S, Albelda MT, Soriano C, et al. Scorpiand-like azamacrocycles prevent the chronic establishment of Trypanosoma cruzi in a murine model. Eur J Med Chem. 2013;70:189–98.10.1016/j.ejmech.2013.09.048
- Olmo F, Rotger C, Ramírez-Macías I, Martínez L, Marín C, Carreras L, et al. Synthesis and biological evaluation of N, N′-squaramides with high in vivo efficacy and low toxicity: toward a low-cost drug against Chagas disease. J Med Chem. 2014;57(3):987–99.10.1021/jm4017015
- da Silva CF, Batista MM, Batista DGJ, de Souza EM, da Silva PB, de Oliveira GM, et al. In vitro and in vivo studies of the trypanocidal activity of a diarylthiophene diamidine against Trypanosoma cruzi. Antimicrob Agents Chemother. 2008;52:3307–14.10.1128/AAC.00038-08
- el Bouhdidi A, Truyens C, Rivera MT, Bazin H, Carlier Y. Trypanosoma cruzi infection in mice induces a polyisotypic hypergammaglobulinaemia and parasite-specific response involving high IgG2a concentrations and highly avid IgG1 antibodies. Parasite Immunol. 1994;16(2):69–76.
- Bryan MA, Guyach SE, Norris KA. Specific humoral immunity versus polyclonal B cell activation in Trypanosoma cruzi infection of susceptible and resistant mice. PLoS Negl Trop Dis. 2010;4(7):e733.10.1371/journal.pntd.0000733
- Bringaud F, Rivière L, Coustou V. Energy metabolism of trypanosomatids: adaptation to available carbon sources. Mol Biochem Parasitol. 2006;149(1):1–9.10.1016/j.molbiopara.2006.03.017
- Ginger ML. Trypanosomatid biology and euglenozoan evolution: new insights and shifting paradigms revealed through genome sequencing. Protist. 2005;156(4):377–92.10.1016/j.protis.2005.10.001
- Turrens J. More differences in energy metabolism between trypanosomatidae. Parasitol Today. 1999;15:346–47.10.1016/S0169-4758(99)01479-9
- Michels PAM, Bringaud F, Herman M, Hannaert V. Metabolic functions of glycosomes in trypanosomatids. Biochimica et Biophysica Acta. 2006;1763:1463–77.10.1016/j.bbamcr.2006.08.019
- Villagran ME, Marin C, Rodriguez-González I, De Diego JA, Sánchez-Moreno M. Use of an iron superoxide dismutase excreted by T. cruzi in the diagnosis of Chagas disease: Seroprevalence in rural zones of the state of Queretaro, Mexico. Am J Trop Med Hyg. 2005;73:510–6.
- Piacenza L, Irigoín F, Alvarez MN, Peluffo G, Taylor MC, Kelly JM, et al. Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression. Biochem J. 2007;403:323–34.10.1042/BJ20061281