Virulence of MRSA USA300 is enhanced by sub-inhibitory concentration of two different classes of antibiotics

References

• Stryjewski ME, Corey GR.. Methicillin-resistant Staphylococcus aureus: an evolving pathogen. Clin Infect Dis. 2014;58( Suppl. 1):S10–S19.
   PubMedGoogle Scholar
• Mlynek KD, Callahan MT, Shimkevitch AV, Farmer JT, Endres JL, Marchand M, et al. Effects of low-dose amoxicillin on Staphylococcus aureus USA300 Biofilms. Antimicrob Agents Chemother. 2016;60:2639–51.
   PubMed Web of Science ®Google Scholar
• Otto M. Community-associated MRSA: what makes them special? Int J Med Microbiol. 2013;303:324–30.
   PubMed Web of Science ®Google Scholar
• Tenover FC, Goering RV. Methicillin-resistant Staphylococcus aureus strain USA300: origin and epidemiology. J Antimicrob Chemother. 2009;64:441–6.
   PubMed Web of Science ®Google Scholar
• Kaïret K, Ho E, Van Kerkhoven D, Boes J, Van Calenbergh S, Pattyn L, et al. USA300, A strain of community-associated methicillin-resistant Staphylococcus aureus, crossing Belgium's borders: outbreak of skin and soft tissue infections in a hospital in Belgium. Eur J Clin Microbiol Infect Dis. 2017;36:905–9.
   PubMed Web of Science ®Google Scholar
• Nimmo GR. USA300 abroad: global spread of a virulent strain of community-associated methicillin-resistant Staphylococcus aureus. Clin Microbiol Infect. 2012;18:725–34.
   PubMed Web of Science ®Google Scholar
• Fossum Moen AE, Tannaes TM, Leegaard TM. USA300 methicillin-resistant Staphylococcus aureus in Norway. APMIS. 2013;121:1091–6.
   PubMed Web of Science ®Google Scholar
• Patel M, Thomas HC, Room J, Wilson Y, Kearns A, Gray J. Successful control of nosocomial transmission of the USA300 clone of community-acquired meticillin-resistant Staphylococcus aureus in a UK paediatric burns centre. J Hosp Infect. 2013;84:319–22.
   PubMed Web of Science ®Google Scholar
• Kamaruzzaman NF, Firdessa R, Good L. Bactericidal effects of polyhexamethylene biguanide against intracellular Staphylococcus aureus EMRSA-15 and USA 300. J Antimicrob Chemother. 2016;71:1252–9.
   PubMed Web of Science ®Google Scholar
• Foster TJ, Hook M. Surface protein adhesins of Staphylococcus aureus. Trends Microbiol. 1998;6:484–8.
   PubMed Web of Science ®Google Scholar
• Rasigade JP, Moulay A, Lhoste Y, Tristan A, Bes M, Vandenesch F, et al. Impact of sub-inhibitory antibiotics on fibronectin-mediated host cell adhesion and invasion by Staphylococcus aureus. BMC Microbiol. 2011;11:263.
   PubMed Web of Science ®Google Scholar
• Komori Y, Aiba T, Sugiyama R, Nakai C, Kawasaki H, Kurosaki Y. Effects of capsaicin on intestinal cephalexin absorption in rats. Biol Pharm Bull. 2007;30:547–51.
   PubMed Web of Science ®Google Scholar
• Haddadin RN, Saleh S, Al-Adham IS, Buultjens TE, Collier PJ. The effect of subminimal inhibitory concentrations of antibiotics on virulence factors expressed by Staphylococcus aureus biofilms. J Appl Microbiol. 2010;108:1281–91.
   PubMed Web of Science ®Google Scholar
• Nucci C, Artini M, Pasmore M, Missiroli F, Costerton JW, Selan L. A microbiological and confocal microscopy study documenting a slime-producing Staphylococcus epidermidis isolated from a nylon corneal suture of a patient with antibiotic-resistant endophthalmitis. Graefes Arch Clin Exp Ophthalmol. 2005;243:951–4.
   PubMed Web of Science ®Google Scholar
• Winder C, Al-Adham I, Abdel Malek S, Buultjens T, Horrocks A, Collier P. Outer membrane protein shifts in biocide resistant Pseudomonas aeruginosa PAO1. J Appl Microbiol. 2000;89:289–95.
   PubMed Web of Science ®Google Scholar
• Rachid S, Ohlsen K, Witte W, Hacker J, Zeibuhr W. Effect of subinhibitory antibiotic concentrations on polysaccharide intercellular adhesin expression in biofilm forming Staphylococcus epidermidis. Antimicrob Agent Chemother. 2000;44:3357–63.
   PubMed Web of Science ®Google Scholar
• Bernardo K, Pakulat N, Fleer S, Schnaith A, Utermohlen O, Krut O, et al. Sub-MIC of linezolid reduce Staphylococcus aureus virulence factor expression. Antimicrob Agent Chemother. 2004;48:546–55.
   PubMed Web of Science ®Google Scholar
• Koszczol C, Bernardo K, Kronke M, Krut O. Subinhibitory quinupristin/dalfopristin attenuates virulence of Staphylococcus aureus. J Antimicrob Chemother. 2006;58:564–74.
   PubMed Web of Science ®Google Scholar
• Shen L, Shi Y, Zhang D, Wei J, Surette M, Duan K. Modulation of secreted virulence factor genes by subinhibitory concentrations of antibiotics in Pseudomonas aeruginosa. J Microbiol. 2008;46:441–7.
   PubMed Web of Science ®Google Scholar
• Hodille E, Rose W, Diep BA, Goutelle S, Lina G, Dumitrescu O. The role of antibiotics in modulating virulence in Staphylococcus aureus. Clin Microbiol Rev. 2017;30:887–917.
   PubMed Web of Science ®Google Scholar
• Stevens DL, Ma Y, Salmi DB, McIndoo E, Wallace RJ, Bryant AE. Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus. J Infect Dis. 2007;195:202–11.
   PubMed Web of Science ®Google Scholar
• Nau R, Eiffert H. Modulation of release of proinflammatory bacterial compounds by antibacterials: potential impact on course of inflammation and outcome in sepsis and meningitis. Clin Microbiol Rev. 2002;15:95–110.
   PubMed Web of Science ®Google Scholar
• Sarasola P, McKellar QA. Pharmacokinetics and applications of ampicillin sodium as an intravenous infusion in the horse. J Vet Pharmacol Ther. 1993;16:63–9.
   PubMed Web of Science ®Google Scholar
• Barbhaiya RH, Knupp CA, Pfeffer M, Pittman KA. Lack of pharmacokinetic interaction between cefepime and amikacin in humans. Antimicrob Agents Chemother. 1992;36:1382–6.
   PubMed Web of Science ®Google Scholar
• Diep BA, Gill SR, Chang RF, Phan TH, Chen JH, Davidson MG, et al. Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus. Lancet. 2006;367:731–9.
   PubMed Web of Science ®Google Scholar
• Clinical and Laboratory Standards Institute (CLSI). CLSI Supplement M100. 27th ed. Wayne, PA: CLSI; 2017 (Performance Standards for Antimicrobial Susceptibility Testing).
   Google Scholar
• Artini M, Papa R, Scoarughi GL, Galano E, Barbato G, Pucci P, et al. Comparison of the action of different proteases on virulence properties related to the staphylococcal surface. J Appl Microbiol. 2013;114:266–77.
   PubMed Web of Science ®Google Scholar
• Papa R, Artini M, Cellini A, Tilotta M, Galano E, Pucci P, et al. A new anti-infective strategy to reduce the spreading of antibiotic resistance by the action on adhesion-mediated virulence factors in Staphylococcus aureus. Microb Pathog. 2013;63:44–53.
   PubMed Web of Science ®Google Scholar
• Couce A, Blázquez J. Side effects of antibiotics on genetic variability. FEMS Microbiol Rev. 2009;33:531–8.
   PubMed Web of Science ®Google Scholar