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Antimicrobial Original Research Paper

In vitro study of antimicrobial activity on Klebsiella Pneumoniae biofilms in endotracheal tubes

, , ORCID Icon, , , & show all
Pages 202-208 | Received 26 Sep 2018, Accepted 27 Mar 2019, Published online: 16 Apr 2019

References

  • Forel J-M, Voillet F, Pulina D, Gacouin A, Perrin G, Barrau K. Ventilator-associated pneumonia and ICU mortality in severe ARDS patients ventilated according to a lung-protective strategy. Crit Care. 2012;16:R65.
  • Hortal J, Muñoz P, Cuerpo G, Litvan H, Rosseel PM, Bouza E. Ventilator-associated pneumonia in patients undergoing major heart surgery: an incidence study in Europe. Crit Care Lond Engl. 2009;13:R80.
  • Bercault N, Boulain T. Mortality rate attributable to ventilator-associated nosocomial pneumonia in an adult intensive care unit: a prospective case-control study. Crit Care Med. 2001;29:2303–2309.
  • Chen Y-Y, Wang F-D, Liu C-Y, Chou P. Incidence rate and variable cost of nosocomial infections in different types of intensive care units. Infect Control Hosp Epidemiol. 2009;30:39–46.
  • Koulenti D, Tsigou E, Rello J. Nosocomial pneumonia in 27 ICUs in Europe: perspectives from the EU-VAP/CAP study. Eur J Clin Microbiol Infect Dis. 2017;36:1999–2006.
  • Yue D, Song C, Zhang B, Liu Z, Chai J, Luo Y, et al. Hospital-wide comparison of health care-associated infection among 8 intensive care units: a retrospective analysis for 2010-2015. Am J Infect Control. 2017;45:e7–13.
  • Donlan RM. Biofilms: microbial life on surfaces. Emerging Infect Dis. 2002;8:881–890.
  • Inglis TJ, Lim TM, Ng ML, Tang EK, Hui KP. Structural features of tracheal tube biofilm formed during prolonged mechanical ventilation. Chest. 1995; 108:1049–1052.
  • Gil-Perotin S, Ramirez P, Marti V, Sahuquillo JM, Gonzalez E, Calleja I, et al. Implications of endotracheal tube biofilm in ventilator-associated pneumonia response: a state of concept. Crit Care Lond Engl. 2012;16:R93.
  • Feldman C, Kassel M, Cantrell J, Kaka S, Morar R, Goolam Mahomed A, et al. The presence and sequence of endotracheal tube colonization in patients undergoing mechanical ventilation. Eur Respir J. 1999;13:546–551.
  • Larson E. Bacterial colonization of tracheal tubes of patients in a surgical intensive care unit. Nurs Res. 1970;19:122–128.
  • Song JY, Cheong HJ, Noh JY, Kim WJ. In vitro comparison of anti-biofilm effects against carbapenem-resistant Acinetobacter baumannii: imipenem, colistin, tigecycline, rifampicin and combinations. Infect Chemother. 2015;47:27–32.
  • Aires CP, Batista MJA, Pitondo-Silva A. Decrease of ceftriaxone susceptibility in Klebsiella pneumoniae according to biofilm maturation. J Glob Antimicrob Resist. 2017;9:126–127.
  • Hengzhuang W, Wu H, Ciofu O, Song Z, Høiby N. In vivo pharmacokinetics/pharmacodynamics of colistin and imipenem in Pseudomonas aeruginosa biofilm infection. Antimicrob Agents Chemother. 2012;56:2683–2690.
  • Stepanovic S, Vukovic D, Dakic I, Savic B, Svabic-Vlahovic M. A modified microtiter-plate test for quantification of staphylococcal biofilm formation. J Microbiol Methods. 2000;40:175–179.
  • . EUCAST. Clinical breakpoints – bacteria (v 5.0). Available from: http://www.eucast.org/clinical_breakpoints/. [Date of Access: 03-Dec-2017]
  • Araújo PA, Mergulhão F, Melo L, Simões M. The ability of an antimicrobial agent to penetrate a biofilm is not correlated with its killing or removal efficiency. Biofouling. 2014;30:675–683.
  • Mah TF, O'Toole GA. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol. 2001;9:34–39.
  • Chung PY. The emerging problems of Klebsiella pneumoniae infections: carbapenem resistance and biofilm formation. FEMS Microbiol Lett. 2016; 363.
  • Flemming H-C, Neu TR, Wozniak DJ. The EPS matrix: the “house of biofilm cells.” J Bacteriol. 2007;189:7945–7947.
  • Suci PA, Mittelman MW, Yu FP, Geesey GG. Investigation of ciprofloxacin penetration into Pseudomonas aeruginosa biofilms. Antimicrob Agents Chemother. 1994;38:2125–2133.
  • Garnacho-Montero J, Corcia-Palomo Y, Amaya-Villar R, Martin-Villen L. How to treat VAP due to MDR pathogens in ICU patients. BMC Infect Dis. 2014; 14:135.
  • Karaiskos I, Giamarellou H. Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches. Expert Opin Pharmacother. 2014;15:1351–1370.
  • Rodvold KA, Hope WW, Boyd SE. Considerations for effect site pharmacokinetics to estimate drug exposure: concentrations of antibiotics in the lung. Curr Opin Pharmacol. 2017;36:114–123.
  • Roy R, Tiwari M, Donelli G, Tiwari V. Strategies for combating bacterial biofilms: a focus on anti-biofilm agents and their mechanisms of action. Virulence. 2018;9:522–554.
  • Sottile FD, Marrie TJ, Prough DS, Hobgood CD, Gower DJ, Webb LX, et al. Nosocomial pulmonary infection: possible etiologic significance of bacterial adhesion to endotracheal tubes. Crit Care Med. 1986;14:265–270.
  • Van Saene HK, Damjanovic V, Williets T, Mostafa SM, Fox MA, Petros AJ. Pathogenesis of ventilator-associated pneumonia: is the contribution of biofilm clinically significant? J Hosp Infect. 1998;38:231–235.
  • Bauer TT, Torres A, Ferrer R, Heyer CM, Schultze-Werninghaus G, Rasche K. Biofilm formation in endotracheal tubes. Association between pneumonia and the persistence of pathogens. Monaldi Arch Chest Dis Arch Monaldi Mal Torace. 2002; 57:84–87.
  • Rello J, Mariscal D, March F, Jubert P, Sanchez F, Valles J, et al. Recurrent Pseudomonas aeruginosa pneumonia in ventilated patients: relapse or reinfection?. Am J Respir Crit Care Med. 1998;157:912–916.
  • Kollef MH, Afessa B, Anzueto A, Veremakis C, Kerr KM, Margolis BD, et al. Silver-coated endotracheal tubes and incidence of ventilator-associated pneumonia: the NASCENT randomized trial. JAMA. 2008;300:805–813.
  • Adair CG, Gorman SP, O'Neill FB, McClurg B, Goldsmith EC, Webb CH. Selective decontamination of the digestive tract (SDD) does not prevent the formation of microbial biofilms on endotracheal tubes. J Antimicrob Chemother. 1993;31:689–697.
  • Adair CG, Gorman SP, Byers LM, Jones DS, Feron B, Crowe M, et al. Eradication of endotracheal tube biofilm by nebulised gentamicin. Intensive Care Med. 2002;28:426.
  • Vandecandelaere I, Coenye T. Microbial composition and antibiotic resistance of biofilms recovered from endotracheal tubes of mechanically ventilated patients. Adv Exp Med Biol. 2015;830:137–155.
  • May RM, Hoffman MG, Sogo MJ, Parker AE, O’Toole GA, Brennan AB, et al. Micro-patterned surfaces reduce bacterial colonization and biofilm formation in vitro: Potential for enhancing endotracheal tube designs. Clin Transl Med. 2014;3:8.

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