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Journal of Chemotherapy Volume 34, 2022 - Issue 4
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Letter to the Editor

The clinical value of penicillin G outweighs its usage restriction due to a too-much concern for hyperkalemia

Hideharu Hagiyaa Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, JapanORCID Iconhttps://orcid.org/0000-0002-5086-1891View further author information
ORCID Icon,
Haruto Yamadab Okayama City Hospital, Infection Control Team, Okayama, JapanView further author information
,
Shiho Kajitab Okayama City Hospital, Infection Control Team, Okayama, JapanView further author information
,
Yoshitaka Iwamotoc Department of General Medicine, Okayama Medical Center, Okayama, JapanView further author information
,
Naofumi Harad Department of Allergy and Respiratory Medicine, Okayama University Hospital, Okayama, JapanView further author information
& Okayama Consortium for Antimicrobial Stewardship Task force (O-CAST)
Pages 277-278 | Received 15 Jul 2021, Accepted 12 Oct 2021, Published online: 01 Nov 2021

References

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  • Lima LM, Silva B. D, Barbosa G, et al. β-lactam antibiotics: an overview from a medicinal chemistry perspective. Eur J Med Chem. 2020;208:112829.
  • Tan SY, Tatsumura Y. Alexander fleming (1881-1955): Discoverer of penicillin. Singapore Med J. 2015;56(7):366–367.
  • Talbot GH. β-Lactam antimicrobials: What have you done for me lately? Ann N Y Acad Sci. 2013;1277:76–83.
  • Bennett JE, Raphael Dolin MJB, editor. Mandell, Douglas, & Bennett’s principles & practice of infectious diseases. 9th ed. Philadelphia (PA): Elsevier/Saunders; 2019; p. 258–260.
  • Tullett GL. Sudden death occurring during “massive-dose” potassium penicillin G therapy. An argument implicating potassium intoxication. Wis Med J. 1970;69(9):216–217.
  • Bryan CS. Treatment of pneumococcal pneumonia: the case for penicillin G. Am J Med. 1999;107(1A):63S–68S.
  • Bryan CS, Talwani R, Stinson MS. Penicillin dosing for pneumococcal pneumonia. Chest. 1997;112(6):1657–1664.

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