396
Views
7
CrossRef citations to date
0
Altmetric
Brief Communications

Trabectedin-irinotecan, a potentially promising combination in relapsed desmoplastic small round cell tumor: report of two cases

ORCID Icon, , , , , , , , , , , ORCID Icon & show all
Pages 163-167 | Received 25 Jan 2022, Accepted 15 Apr 2022, Published online: 26 Apr 2022

References

  • Kushner BH, LaQuaglia MP, Wollner N, et al. Desmoplastic small round-cell tumor: prolonged progression-free survival with aggressive multimodality therapy. J Clin Oncol. 1996;14(5):1526–1531.
  • Honoré C, Amroun K, Vilcot L, et al. Abdominal desmoplastic small round cell tumor: multimodal treatment combining chemotherapy, surgery, and radiotherapy is the best option. Ann Surg Oncol. 2015;22(4):1073–1079. Apr
  • Lal DR, Su WT, Wolden SL, et al. Results of multimodal treatment for desmoplastic small round cell tumors. J Pediatr Surg. 2005;40(1):251–255.
  • Desai NB, Stein NF, LaQuaglia MP, et al. Reduced toxicity with intensity modulated radiation therapy (IMRT) for desmoplastic small round cell tumor (DSRCT): an update on the whole abdominopelvic radiation therapy (WAP-RT) experience. Int J Radiat Oncol Biol Phys. 2013;85(1):e67–e72.
  • Ferrari A, Bergamaschi L, Chiaravalli S, et al. Multiagent chemotherapy including IrIVA regimen and maintenance therapy in the treatment of desmoplastic small round cell tumor. Tumori. 2022;108(1):93–97. Online ahead of print.
  • Bisogno G, Ferrari A, Rosolen A, et al. Sequential intensified chemotherapy with stem cell rescue for children and adolescents with desmoplastic small round-cell tumor. Bone Marrow Transplant. 2010;45(5):907–911.
  • Hayes-Jordan A, Green HL, Lin H, et al. Complete cytoreduction and HIPEC improves survival in desmoplastic small round cell tumor. Ann Surg Oncol. 2014;21(1):220–224.
  • Italiano A, Kind M, Cioffi A, et al. Clinical activity of sunitinib in patients with advanced desmoplastic round cell tumor: a case series. Target Oncol. 2013;8(3):211–213.
  • López-González A, Cantos B, Tejerina E, et al. Activity of trabectedin in desmoplastic small round cell tumor. Med Oncol. 2011;28(S1):644–S646.
  • Frezza AM, Whelan JS, Dileo P. Trabectedin for desmoplastic small round cell tumours: a possible treatment option? Clin Sarcoma Res. 2014;4:3.
  • Brunetti AE, Delcuratolo S, Lorusso V, et al. Third-Line trabectedin for a metastatic desmoplastic small round cell tumour treated with multimodal therapy. Anticancer Res. 2014;34(7):3683–3688.
  • Uboldi S, Craparotta I, Colella G, et al. Mechanism of action of trabectedin in desmoplastic small round cell tumor cells. BMC Cancer. 2017;17(1):107.
  • Verret B, Honore C, Dumont S, et al. Trabectedin in advanced desmoplastic round cell tumors: a retrospective single-center series. Anticancer Drugs. 2017;28(1):116–119. Jan
  • Rosoff PM, Bayliff S. Successful clinical response to irinotecan in desmoplastic round blue cell tumor. Med Pediatr Oncol. 1999;33(5):500–503.
  • Liu KX, Collins NB, Greenzang KA, et al. The use of interval-compressed chemotherapy with the addition of vincristine, irinotecan, and temozolomide for pediatric patients with newly diagnosed desmoplastic small round cell tumor. Pediatr Blood Cancer. 2020;67(10):e28559.
  • Gronchi A, Hindi N, Cruz J, et al. Trabectedin and RAdiotherapy in soft tissue sarcoma (TRASTS): results of a phase I study in myxoid liposarcoma from spanish (GEIS), italian (ISG), french (FSG) sarcoma groups. EClinicalMedicine . 2019;9:35–43.
  • Grohar PJ, Segars LE, Yeung C, et al. Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits ewing sarcoma cell growth. Clin Cancer Res. 2014;20(5):1190–1203.
  • Riccardi A, Meco D, Ubezio P, et al. Combination of trabectedin and irinotecan is highly effective in a human rhabdomyosarcoma xenograft. Anticancer Drugs. 2005;16(8):811–815.
  • Higuchi T, Miyake K, Oshiro H, et al. Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model. Biochem Biophys Res Commun. 2019;513(2):326–331.
  • Ponce Aix S, Cote GM, Falcon Gonzalez A, et al. Lurbinectedin (LUR) in combination with irinotecan (IRI) in patients (pts) with advanced solid tumors: updated results from a phase Ib-II trial. J Clin Oncol. 2020;38(15_suppl):3514–3514.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.