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Anticancer Original Research Papers

LncRNA-IQCH-AS1 sensitizes thyroid cancer cells to doxorubicin via modulating the miR-196a-5p/PPP2R1B signalling pathway

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Pages 250-258 | Received 21 Nov 2021, Accepted 21 May 2022, Published online: 16 Aug 2022

References

  • Agosto Salgado S. Evolution of anaplastic thyroid cancer management: perspectives in the era of precision oncology. Ther Adv Endocrinol Metab. 2021;12:20420188211054692.
  • Tarabichi M, Demetter P, Craciun L, et al. Thyroid cancer under the scope of emerging technologies. Mol Cell Endocrinol. 2022;541:111491.
  • Cabanillas ME, Ryder M, Jimenez C. Targeted therapy for advanced thyroid cancer: Kinase inhibitors and Beyond. Endocr Rev. 2019;40(6):1573–1604.
  • Roychoudhury S, Kumar A, Bhatkar D, et al. Molecular avenues in targeted doxorubicin cancer therapy. Future Oncol. 2020;16(11):687–700.
  • Eide S, Feng ZP. Doxorubicin chemotherapy-induced “chemo-brain”: meta-analysis. Eur J Pharmacol. 2020;881:173078.
  • Al-Malky HS, Al Harthi SE, Osman AM. Major obstacles to doxorubicin therapy: cardiotoxicity and drug resistance. J Oncol Pharm Pract. 2020;26(2):434–444.
  • Goodall GJ, Wickramasinghe VO. RNA in cancer. Nat Rev Cancer. 2021;21(1):22–36.
  • Statello L, Guo CJ, Chen LL, et al. Gene regulation by long non-coding RNAs and its biological functions. Nat Rev Mol Cell Biol. 2021;22(2):96–118.
  • Peng WX, Koirala P, Mo YY. LncRNA-mediated regulation of cell signaling in cancer. Oncogene. 2017;36(41):5661–5667.
  • Paraskevopoulou MD, Hatzigeorgiou AG. Analyzing MiRNA-LncRNA interactions. Methods Mol Biol. 2016;1402:271–286.
  • Duff MO, Olson S, Wei X, et al. Genome-wide identification of zero nucleotide recursive splicing in drosophila. Nature. 2015;521(7552):376–379.
  • Tamaki M, Goi T, Hirono Y, et al. PPP2R1B gene alterations inhibit interaction of PP2A-Abeta and PP2A-C proteins in colorectal cancers. Oncol Rep. 2004;11(3):655–659.
  • Campbell IG, Manolitsas T. Absence of PPP2R1B gene alterations in primary ovarian cancers. Oncogene. 1999;18(46):6367–6369.
  • Zhang Y, Talmon G, Wang J. MicroRNA-587 antagonizes 5-FU-induced apoptosis and confers drug resistance by regulating PPP2R1B expression in colorectal cancer. Cell Death Dis. 2015;6:e1845.
  • Chou HC, Chen CH, Lee HS, et al. Alterations of tumour suppressor gene PPP2R1B in hepatocellular carcinoma. Cancer Lett. 2007;253(1):138–143.
  • Li JH, Liu S, Zhou H, et al. starBase v2.0: decoding miRNA-ceRNA, miRNA-ncRNA and protein-RNA interaction networks from large-scale CLIP-Seq data. Nucleic Acids Res. 2014;42:D92–97.
  • Lan X, Zhang H, Wang Z, et al. Genome-wide analysis of long noncoding RNA expression profile in papillary thyroid carcinoma. Gene. 2015;569(1):109–117.
  • Xin H, Wang C, Liu Z. miR-196a-5p promotes metastasis of colorectal cancer via targeting IκBα. BMC Cancer. 2019;19(1):30.
  • Li S, Zhou J, Wang Z, et al. Long noncoding RNA GAS5 suppresses triple negative breast cancer progression through inhibition of proliferation and invasion by competitively binding miR-196a-5p. Biomed Pharmacother. 2018;104:451–457.
  • Sang C, Chao C, Wang M, et al. Identification and validation of hub microRNAs dysregulated in esophageal squamous cell carcinoma. Aging (Albany NY). 2020;12(10):9807–9824.

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