Transcriptional regulation of the Drosophila proliferating cell nuclear antigen gene and raf proto‐oncogene by ursolic acid in Drosophila cultured Kc cells

References

• Ambrosio , L , Mahowald , AP and Perrimon , N . 1989 . Requirement of the Drosophila raf homolog for torso function . Nature , 342 : 288 – 291 .
   PubMed Web of Science ®Google Scholar
• Bond , BJ and Davison , N . 1986 . The Drosophila melanogaster actin 5C gene uses two transcription initiation sites and three poly adenylation sites to express multiple mRNA species . Mol Cell Biol , 8 : 2080 – 2088 .
   Google Scholar
• Bravo , R , Frank , R , Blundell , PA and MacDonald‐Bravo , H . 1987 . Cyclin/PCNA is the auxiliary protein of DNA polymerase δ . Nature , 326 : 515 – 517 .
   PubMed Web of Science ®Google Scholar
• Buller , M and Dawson , M . 1992 . Cell Culture , 28 – 30 . Blackwell Scientific Pub .
   Google Scholar
• Cha , HJ , Bae , SK , Lee , HY , Lee , OH , Sato , H , Seiki , M , Park , BC and Kim , KW . 1996 . Anti‐invasive activity of ursolic acid correlates with the reduced expression of matrix metalloproteinase9 (MMP‐9) in HT1080 human fibrosarcoma cells . Cancer Res , 56 : 2281 – 2284 .
   PubMed Web of Science ®Google Scholar
• Crews , CM and Erickson , RL . 1993 . Extracellular signals and reversible protein phosphorylation: what to Mek of it all . Cell , 74 : 215 – 217 .
   PubMed Web of Science ®Google Scholar
• Davis , RJ . 1993 . The mitogen‐activated protein kinase signal transduction pathway . J Biol Chem , 268 : 14533 – 14556 .
   Web of Science ®Google Scholar
• Di Nocera , PP and Dawid , IB . 1983 . Transient expression of genes introduced into cultured cells of Drosophila . Proc Natl Acad Sci USA , 80 : 7095 – 7098 .
   PubMed Web of Science ®Google Scholar
• Echalier , G and Ohanessian , A . 1970 . In vitro culture of Drosophila melanogater embryonic cells . In vitro , 6 : 162 – 172 .
   PubMedGoogle Scholar
• Erwin , BG , Stoscheck , CM and Florini , JR . 1981 . A rapid fluorometric method for the estimation of DNA in cultured cells . Anal Biochem , 110 : 291 – 294 .
   PubMed Web of Science ®Google Scholar
• Hata , M , Inoue , YH , Yoo , MA and Nishida , Y . 1994 . Multiple functions of raf proto‐oncogene during development from analysis of a temperature‐sensitive mutation of Drosophila . Int J Dev Biol , 38 : 329 – 335 .
   PubMed Web of Science ®Google Scholar
• Hirose , F , Yamaguchi , M , Handa , H , Inomata , Y and Matsukage , A . 1993 . Novel 8‐base pair sequence (Drosophila DNA replication‐related element) and specific binding factor involved in the expression of Drosophila genes for DNA polymerase a and proliferating cell nuclear antigen . J Biol Chem , 268 : 2092 – 2099 .
   PubMed Web of Science ®Google Scholar
• Hirose , F , Yamaguchi , M and Matsukage , A . 1994 . Repression of regulatory factor for Drosophila DNA replication‐related gene promoters by zerknüllt homeodomain protein . J Biol Chem , 269 : 2937 – 2942 .
   PubMed Web of Science ®Google Scholar
• Huang , MT , Ho , CT , Wang , ZY , Ferraro , T , Lou , YR , Stauber , K , Ma , W , Georgiadis , C , Laskin , JD and Conney , AH . 1994 . Inhibition of skin tumorigenesis by rosemary and its constituents carnosol and ursolic acid . Cancer Res , 54 : 701 – 708 .
   PubMed Web of Science ®Google Scholar
• Jaskulski , D , De Riel , JK , Mercer , WE , Calabretta , B and Baserga , R . 1988 . Inhibition of cellular proliferation by anti‐sense oligodeoxynucleotides to PCNA cyclin . Science , 240 : 1544 – 1546 .
   PubMed Web of Science ®Google Scholar
• Lee , H‐H , Chiang , W‐H , Chiang , S‐H , Liu , Y‐C , Hwang , J and Ng , S‐Y . 1995 . Regulation of cyclin D1, DNA topoisomerase I, and proliferating cell nuclear antigen promoters during the cell cycle . Gene Exp , 4 : 95 – 109 .
   PubMedGoogle Scholar
• Lee , HY , Chung , HY , Kim , KH , Lee , JJ and Kim , KW . 1994 . Induction of differentiation in the cultured F9 teratocarcinoma stem cells by triterpene acids . J Cancer Res Clin Oncol , 120 : 513 – 518 .
   PubMed Web of Science ®Google Scholar
• Liu , YC , Marraccino , RL , Keng , PC , Bambara , RA , Lord , EM , Chow , WG and Zain , SB . 1989 . Requirement for proliferating cell nuclear antigen expressed during stages of the Chinese hamster ovary cell cycle . Biochemistry , 18 : 2967 – 2974 .
   Web of Science ®Google Scholar
• Matsukage , A , Kitani , H , Yamaguchi , M , Kusakabe , M , Morita , T and Koshida , Y . 1986 . Differentiation of lens and neural cells in chicken embryos is accompanied by simultaneous decay of DNA replication machinery . Dev Biol , 117 : 226 – 232 .
   PubMed Web of Science ®Google Scholar
• Matsukage , A , Hirose , F and Yamaguchi , M . 1994 . Transcriptional regulation of DNA replicationrelated genes in cell growth, differentiation and oncogenesis . Jpn J Cancer Res , 85 : 1 – 8 .
   PubMedGoogle Scholar
• Melnick , MB , Perkins , LA , Lee , M , Ambrosio , L and Perrimon , N . 1993 . Developmental and molecular characterization of mutations in the Drosophila‐raf serine/threonine protein kin‐ase . Development , 118 : 127 – 138 .
   PubMed Web of Science ®Google Scholar
• Miyachi , K , Fritzler , MJ and Tan , EM . 1978 . Autoantibody to a nuclear antigen in proliferating cells . J Immunol , 121 : 2228 – 2234 .
   PubMed Web of Science ®Google Scholar
• Miyazawa , H , Izumi , M , Tada , S , Takada , R , Masutani , M , Ui , M and Hanaoka , F . 1993 . Molecular cloning of the cDNAs for the four subunits of mouse DNA polymerase alpha‐primase complex and their gene expression during cell proliferation and the cell cycle . J Biol Chem , 268 : 8111 – 8122 .
   PubMed Web of Science ®Google Scholar
• Morrison , DK . 1990 . The Raf‐1 kinase as a transducer of mitogenic signals . Cancer Cells , 2 : 377 – 382 .
   PubMed Web of Science ®Google Scholar
• Nevins , JR . 1992 . E2F: a link between the Rb tumor suppressor protein and viral oncoproteins . Science , 258 : 424 – 429 .
   PubMed Web of Science ®Google Scholar
• Nishida , Y , Hata , M , Ayaki , T , Ryo , H , Yamagata , M , Shimizu , K and Nishizuka , Y . 1988 . Proliferation of both somatic and germ cells is affected in the Drosophila mutants of raf proto‐oncogene . EMBO J , 7 : 776 – 781 .
   Web of Science ®Google Scholar
• Ohigashi , H , Takamura , H , Koshimizu , K , Tokuda , H and Ito , Y . 1986 . Search for possible antitumor promoters by inhibition of 12‐O‐tetradecanoylphorbol‐13‐acetate‐induced Epstein‐Barr virus activation; ursolic acid and oleanolic acid from an antiinflammatory Chinese medicinal plant, Glechoma hederaceae L . Cancer Lett , 30 : 143 – 151 .
   PubMed Web of Science ®Google Scholar
• Ohno , K , Hirose , F , Sakaguchi , K , Nishida , Y and Matsukage , A . 1996 . Transcriptional regulation of the Drosophila Cyc A gene by the DNA replication‐related element (DRE) and DRE‐binding factor (DREF) . Nucleic Acids Res , 24 : 3942 – 3946 .
   PubMed Web of Science ®Google Scholar
• Ohtani , K and Nevins , JR . 1994 . Functional properties of a Drosophila homolog of the E2F1 gene . Mol Cell Biol , 14 : 1603 – 1612 .
   PubMed Web of Science ®Google Scholar
• Perrimon , N , Engstrom , L and Mahowald , AP . 1985 . A pupal lethal mutation with a paternally influenced maternal effect on embryonic development in Drosophila melanogaster . Dev Biol , 110 : 480 – 491 .
   PubMed Web of Science ®Google Scholar
• Prelich , G , Tan , CK , Kostura , M , Mathews , MB , So , AG , Downnewy , KM and Stillman , B . 1987a . Functional identify of proliferating cell nuclear antigen and a DNA polymerase 5 auxiliary protein . Nature , 326 : 517 – 520 .
   PubMed Web of Science ®Google Scholar
• Prelich , G , Kostura , M , Marshak , DR , Mathews , MB and Stillman , B . 1987b . The cell‐cycle regulated proliferating cell nuclear antigen is required for SV40 DNA replication in vitro . Nature , 326 : 471 – 475 .
   PubMed Web of Science ®Google Scholar
• Rapp , UR . 1991 . Role of Raf‐1 serine/threonine protein kinase in growth factor signal transduction . Oncogene , 6 : 495 – 500 .
   PubMed Web of Science ®Google Scholar
• Roberts , TM . 1992 . A signal chain of events . Nature , 360 : 534 – 535 .
   PubMed Web of Science ®Google Scholar
• Ryu , JR , Choi , TY , Kwon , EJ , Lee , WH , Nishida , Y , Hayashi , Y , Matsukage , A , Yamaguchi , M and Yoo , MA . 1997 . Transcriptional regulation of the Drosophila‐raf proto‐oncogene by the DNA replication‐related element (DRE)/DRE‐binding factor (DREF) system . Nucleic Acids Res , 25 : 794 – 799 .
   PubMed Web of Science ®Google Scholar
• Slansky , JE , Li , Y , Kaelin , WG and Farnham , PJ . 1993 . A protein synthesis‐dependent increase in E2F1 mRNA correlates with growth regulation of the dihydrofolate reductase promoter . Mol Cell Biol , 13 : 1610 – 1618 .
   PubMed Web of Science ®Google Scholar
• Werner , EJ , Walenga , RW , Dubowy , RL , Boone , S and Stuart , M . 1985 . Inhibition of human malignant neuroblastoma cell DNA synthesis by lipoxygenase metabolites of arachidonic acid . Cancer Res , 45 : 561 – 563 .
   PubMed Web of Science ®Google Scholar
• Yamaguchi , M , Hirose , F , Nishida , Y and Matsukage , A . 1991 . Repression of Drosophila proliferating cell nuclear antigene gene promoter by zerknüllt protein . Mol Cell Biol , 11 : 4909 – 4917 .
   PubMed Web of Science ®Google Scholar
• Yamaguchi , M , Hayashi , Y and Matsukage , A . 1988 . Mouse DNA polymerase β gene promoter: fine mapping and involvement of Sp1‐like mouse transcription factor in its function . Nucleic Acids Res , 16 : 8773 – 8787 .
   PubMed Web of Science ®Google Scholar
• Yamaguchi , M , Hayashi , Y , Matsuoka , S , Takahashi , T and Matsukage , A . 1994 . Differential effect of p53 on the promoters of mouse DNA polymerase β gene and proliferating cell nuclear antigen gene . Eur J Biochem , 221 : 227 – 237 .
   PubMedGoogle Scholar
• Yamaguchi , M , Hayashi , Y , Nishimoto , Y , Hirose , F and Matsukage , A . 1995a . A nucleotide sequence essential for the function of DRE, a common promoter element for Drosophila DNA replication‐related genes . J Biol Chem , 270 : 15808 – 15814 .
   PubMed Web of Science ®Google Scholar
• Yamaguchi , M , Hayashi , Y and Matsukage , A . 1995b . Essential role of E2F recognition sites in regulation of the proliferating cell nuclear antigen gene promoter during Drosophila development . J Biol Chem , 270 : 25159 – 25165 .
   PubMed Web of Science ®Google Scholar
• Yamaguchi , M , Nishida , Y , Moriuchi , T , Hirose , F , Hui , C‐C , Suzuki , Y and Matsukage , A . 1990 . Drosophila proliferating cell nuclear antigen (cyclin) gene: structure, expression during development, and specific binding of homeodomain proteins to its 5'‐flanking region . Mol Cell Biol , 10 : 872 – 879 .
   PubMed Web of Science ®Google Scholar
• To whom correspondence should be addressed. Tel: 82–51–510–2278, Fax: 82–51–513–9258.
   Google Scholar