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Original Articles

Genetic polymorphisms of t‐PA and PAI‐1 genes in the Korean population

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Pages 249-253 | Received 01 Jun 2003, Accepted 16 Jul 2003, Published online: 22 Nov 2010

References

  • Andreasen , PA , Georg , B , Lund , LR , Riccio , A and Stacey , SN . 1990 . Plasminogen activator inhibitors: hormonally regulated serpins . Mol Cell Endocrinol , 68 : 1 – 19 .
  • Benza , RL , Grenett , HE , Li , XL , Reeder , VC , Brown , SL , Go , RCP , Hanson , KA , Perry , GJ , Holman , WL , McGiffin , DC , Kirk , KA and Booyse , FM . 1998 . Gene polymorphisms for PAI‐1 are associated with the angiographic extent of coronary artery disease . Thromb Thrombol , 5 : 143 – 150 .
  • Collen , D . 1980 . On the regulation and control of fibrinolysis . Thromb Haemost , 43 : 77 – 89 .
  • Dawson , SJ , Hamsten , A , Wiman , B , Henney , A and Humphries , S . 1991 . Genetic variation at the plasminogen activator inhibitor‐1 locus is associated with altered levels of plasminogen activator inhibitor‐1 activity . Arterioscler Thromb , 11 : 183 – 190 .
  • Falk , G , Almqvist , Å , Nordenhem , A , Svensson , H and Wiman , B . 1995 . Allele specific PCR for detection of a sequence polymorphism in the promoter region of the plasminogen activator inhibitor‐1 (PAI‐1) gene . Fibrinolysis , 9 : 170 – 174 .
  • Fridewald , WT , Levy , RI and Friedrickson , DS . 1972 . Estimation of the concentration of low‐density lipoprotein cholesterol in plasma without the use of the preparative ultracentrifuge . Clin Chem , 18 : 499 – 502 .
  • Grenett , HE , Khan , N , Jiang , W and Booyse , F . 2000 . Identification of the Hind III polymorphic site in the PAI‐1 gene: analysis of the PAI‐1 Hind III polymorphism by PCR . Genet Test , 4 : 65 – 68 .
  • Henry , M , Chomiki , N , Scarabin , PY , Alessi , MC , Peiretti , F , Arveiler , D , Ferrières , J , Evans , A , Amouyel , P , Poirier , O , Cambien , F and Juhan‐Vague . 1997 . Five frequent polymorphisms of the PAI‐1 gene: lack of association between genotypes, PAI‐1 activity, and triglyceride levels in a healthy population . Artheroscler Thromb Vasc Biol , 17 : 851 – 858 .
  • Jeng , JR , Ham , HJ , Yuen , KC , Jeng , CY and Shieh , SM . 1998 . Plasminogen activator inhibitor‐1 and angiotensin I converting enzyme gene polymorphism in patients with hypertension . Am J Hypertens , 11 : 235 – 239 .
  • Jeng , JR , Sheu , WHH , Jeng , CY , Huang , SH and Shieh , SM . 1996 . Impaired fibrinolysis and insulin resistance in patients with hypertension . Am J Hypertens , 9 : 484 – 490 .
  • Kang , BY , Kim , KT , Eo , HS , Lee , KH , Hong , SS , Shin , JH and Lee , CC . 2000 . Association between genetic variation of the insulin receptor gene and essential hypertension in the Korean population . Korean J Biol Sci , 4 : 87 – 90 .
  • Kim , HS , Hwang , KY , Chung , IK , Park , SH , Lee , MH , Kim , SJ and Hong , SY . 2003 . Tissue plasminogen activator and plasminogen activator inhibitor type 1 gene polymorphism in patients with gastric ulcer complicated with bleeding . J Korean Med Sci , 18 : 58 – 64 .
  • Kim , JQ , Song , JH , Park , YB and Hong , SS . 1998 . Molecular basis of coronary heart disease . J Korean Med Sci , 13 : 1 – 15 .
  • Klinger , KW , Winqvist , R , Riccio , A , Andreasen , PA , Sartorio , R , Nielsen , LS , Stuart , N , Stanislovitis , P , Watkins , P and Douglas , R . 1987 . Plasminogen activator inhibitor type 1 gene is located at region q21.3‐q22 of chromosome 7 and genetically linked with cystic fibrosis . Proc Natl Acad Sci USA , 84 : 8548 – 8552 .
  • Kooistra , T , Bosma , PJ , Törs , HAM , van den Berg , AP , Meyer , P and Princen , HMG . 1989 . Plasminogen activator inhibitor 1: biosynthesis and mRNA level are increased by insulin in cultured human hepatocyte . Thromb Haemost , 62 : 723 – 728 .
  • Lander , ES and Schork , NJ . 1994 . Genetic dissection of complex traits . Science , 265 : 2037 – 2048 .
  • Landin , K , Tengborn , L and Smith , U . 1990 . Elevated fibrinogen and plasminogen activator inhibitor‐1 (PAI‐1) in hypertension are related to metabolic risk factors for cardiovascular disease . J Int Med , 227 : 273 – 278 .
  • Lifton , RP , Dluhy , RG , Powers , M , Rich , GM , Cook , S , Ulick , S and Lalouel , J‐M A . 1992 . Chimaeric 11 β‐hydroxylase/aldosterone synthase gene causes glucocorticoid‐remediable aldosteronism and human hypertension . Nature , 355 : 262 – 265 .
  • Loskutoff , DJ . 1991 . Regulation of PAI‐1 gene expression . Fibrinolysis , 5 : 197 – 206 .
  • Luft , FC . 1999 . Bad genes, good people, association, linkage, longevity and the prevention of cardiovascular disease . Clin Exp Pharmacol Physiol , 26 : 576 – 579 .
  • Mansfield , MW , Stickland , MH and Grant , PJ . 1995 . Environmental and genetic factors in relation to elevated circulating levels of plasminogen activator inhibitor‐1 in Caucasian patients with non‐insulin‐dependent diabetes mellitus . Thromb Haemost , 74 : 842 – 847 .
  • McCormack , LJ , Nagi , DK , Stickland , MH , Mansfield , MW , Mohamed‐Ali , V , Yudkin , JS , Knowler , WC and Grant , PJ . 1996 . Promoter (4G/5G) plasminogen activator inhibitor‐1 genotype in Pima Indians: relationship to plasminogen activator inhibitor‐1 levels and features of the insulin resistance syndrome . Diabetologia , 39 : 1512 – 1518 .
  • Molnar‐Gabor , E , Endreffy , E and Rozsasi , A . 2000 . HLA‐DRB1, ‐DQA1, and DQB1 genotypes in patients with nasal polyposis . Laryngoscope , 110 : 422 – 425 .
  • Mune , T , Rogerson , FM , Nikkila , H , Agarwal , AK and White , PC . 1995 . Human hypertension caused by mutations in the kidney isozyme of 11 beta‐hydroxysteroid dehydrogenase . Nat Genet , 10 : 394 – 399 .
  • Novick , GE , Novick , CC , Yunis , J , Yunis , E , de Mayolo , PA , Scheer , WD , Deninger , PL , Stoneking , M , York , DS , Batzer , MA and Herrera , RJ . 1998 . Polymorphic Alu insertions and the Asian origin of native American populations . Hum Biol , 70 : 23 – 39 .
  • Ny , T , Sawdey , M , Lawrence , D , Millan , JL and Loskutoff , DJ . 1986 . Cloning and sequencing of a cDNA coding for the human beta‐migrating endothelial‐cell‐type plasminogen activator inhibitor . Proc Natl Acad Sci USA , 83 : 6776 – 6780 .
  • Orita , M , Iwahana , H , Kanazawa , H , Hayashi , K and Sekiya , T . 1989a . Detection of polymorphisms of human DNA by gel electrophoresis as single‐strand conformation polymorphisms . Proc Natl Acad Sci USA , 86 : 2766 – 2770 .
  • Orita , M , Suzuki , T , Sekiya , T and Hayashi , K . 1989b . Rapid and sensitive detection of point mutations and genetic polymorphisms using polymerase chain reaction . Genomics , 5 : 874 – 879 .
  • Shimkets , RA , Warnock , DG , Bositis , CM , Nelson‐Williams , C , Hansson , JH , Schambelan , M , Gill , JR Jr. , Ulick , S , Milora , RV and Findling , JW . 1994 . Liddle's syndrome: heritable human hypertension caused by mutations in the beta subunit of the epithelial sodium channel . Cell , 79 : 407 – 414 .
  • Song , J , Yoon , YM , Jung , HJ , Hong , SH , Park , H and Kim , JQ . 2000 . Plasminogen activator inhibitor‐1 4G/5G promoter polymorphism and coagulation factor VII arg353?Gln polymorphism in Korean patients with coronary artery disease . J Korean Med Sci , 15 : 146 – 152 .
  • Teger‐Nilsson , AC , Larsson , T , Hjemdahl , P and Olsson , G . 1991 . Fibrinogen and plasminogen activator inhibitor‐1 levels in hypertension and coronary heart disease . Circulation , 84 ( Suppl VI ) : VI‐72 – VI‐77 .
  • Tishkoff , SA , Ruano , G , Kidd , JR and Kidd , KK . 1996 . Distribution and frequency of a polymorphic Alu insertion at the plasminogen activator locus in humans . Hum Genet , 97 : 759 – 764 .
  • van den Eijnden‐Schrauwen , Y , Lakenberg , N , Emeis , JJ and de Knijff , P . 1995 . Alu‐repeat polymorphism in the tissue‐type plasminogen activator (tPA) gene does not affect basal endothelial tPA synthesis . Thromb Haemost , 74 : 1202
  • van der Bom , JG , de Knijff , P , Haverkate , F , Bots , ML , Meijer , P , de Jong , PTVM , Hofman , A , Kluft , C and Grobbee , DE . 1997 . Tissue plasminogen activator and risk of myocardial infarction . Circulation , 95 : 2623 – 2627 .
  • Wang , B , Zhou , X , Dang , A , Liu , G and He , R . 2002 . Alu‐repeat polymorphism in the gene coding for tissue‐plasminogen activator and the risk of hypertension in a Chinese Han population . Hypertens Res , 25 : 949 – 953 .
  • Wiman , B and Hamsten , A . 1990 . The fibrinolytic enzyme system and its role in the etiology of thromboembolic disease. Semin . Thromb Hemost , 16 : 207 – 216 .
  • Yang‐Feng , TL , Opdenakker , G , Volckaert , G and Francke , U . 1986 . Human tissue‐type plasminogen activator gene located near chromosomal breakpoint in myeloproliferative disorder . Am J Hum Genet , 39 : 79 – 87 .
  • To whom correspondence should be addressed. Tel: 82–2–3399–3561, Fax: 82–2–971–6812 E‐mail: [email protected]

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