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Research Articles

Effects of Culture Mechanism of Cinnamomum kanehirae and C. camphora on the Expression of Genes Related to Terpene Biosynthesis in Antrodia cinnamomea

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Pages 121-131 | Received 22 Nov 2021, Accepted 24 Mar 2022, Published online: 21 Apr 2022

References

  • Rao YK, Geethangili M, Tzeng YM. Development of a high-performance liquid chromatography method for the quantitative determination of bioactive triterpenoids in the extracts of Antrodia camphorata. Anal Methods. 2013;5(20):5724–5730.
  • Lu MY, Fan WL, Wang WF, et al. Genomic and transcriptomic analyses of the medicinal fungus Antrodia cinnamomea for its metabolite biosynthesis and sexual development. Proc Natl Acad Sci USA. 2014;111(44):E4743–E4752.
  • Yeh CT, Rao YK, Yao CJ, et al. Cytotoxic triterpenes from Antrodia camphorata and their mode of action in HT-29 human colon cancer cells. Cancer Lett. 2009;285(1):73–79.
  • Toyomasu T. Recent advances regarding diterpene cyclase genes in higher plants and fungi. Biosci Biotechnol Biochem. 2008;72(5):1168–1175.
  • Hsiao G, Shen MY, Lin KH, et al. Antioxidative and hepatoprotective effects of Antrodia camphorata extract. J Agric Food Chem. 2003;51(11):3302–3308.
  • Joshi RA. Antrodia camphorata with potential anticancerous activities: a review. J Med Plant. 2017;5(1):284–291.
  • Qiao X, Wang Q, Ji S, et al. Metabolites identification and multi-component pharmacokinetics of ergostane and lanostane triterpenoids in the anticancer mushroom Antrodia cinnamomea. J Pharm Biomed Anal. 2015;111:266–276.
  • Geethangili M, Tzeng YM. Review of pharmacological effects of antrodia camphorata and its bioactive compounds. Evid Based Complement Alternat Med. 2011;2011(17):212641–21427X.
  • Li ZW, Kuang Y, Tang SN, et al. Hepatoprotective activities of Antrodia camphorata and its triterpenoid compounds against CCl4-induced liver injury in mice. J Ethnopharmacol. 2017;206:31–39.
  • Kuo YH, Lin CH, Shih CC. Antidiabetic and antihyperlipidemic properties of a triterpenoid compound, dehydroeburicoic acid, from Antrodia camphorata in vitro and in streptozotocin-induced mice. J Agric Food Chem. 2015;63(46):10140–10151.
  • Du YC, Wu TY, Chang FR, et al. Chemical profiling of the cytotoxic triterpenoid-concentrating fraction and characterization of ergostane stereo-isomer ingredients from Antrodia camphorata. J Pharm Biomed Anal. 2012;58(1):182–192.
  • Tien AJ, Chien CY, Chen YH, et al. Fruiting bodies of Antrodia cinnamomea and its active triterpenoid, antcin K, ameliorates N-nitrosodiethylamine-induced hepatic inflammation, fibrosis and carcinogenesis in rats. Am J Chin Med. 2017;45(1):1–26.
  • Thapa HR, Naik MT, Shigeru O, et al. A squalene synthase-like enzyme initiates production of tetraterpenoid hydrocarbons in Botryococcus braunii race L. Nat Commun. 2016;7:11198.
  • Lu ZM. Study on submerged culture of Antrodia cinnamomea its triterpenoids. Wuxi: Jiangnan University; 2009.
  • Ma TW, Lai Y, Yang FC. Enhanced production of triterpenoid in submerged cultures of Antrodia cinnamomea with the addition of citrus peel extract. Bioprocess Biosyst Eng. 2014;37(11):2251–2261.
  • Chen SY, Lee YR, Hsieh MC, et al. Enhancing the anticancer activity of Antrodia cinnamomea in hepatocellular carcinoma cells via cocultivation with ginger: the impact on cancer cell survival pathways. Front Pharmacol. 2018;9(780):780.
  • Fradj N, Santos K, Montigny ND, et al. RNA-Seq de novo assembly and differential transcriptome analysis of chaga (Inonotus obliquus) cultured with different betulin sources and the regulation of genes involved in terpenoid biosynthesis. Int J Cell Sci Mol Biol. 2019;20(18):4334.
  • Bastos DZ, Pimentel IC, de Jesus DA, et al. B.H. Biotransformation of betulinic and betulonic acids by fungi. Phytochemistry. 2007;68(6):834–839.
  • Li G, Lou HX. Strategies to diversify natural products for drug discovery. Med Res Rev. 2018;38(4):1255–1294.
  • Shu CH, Wu CJ, Hsiao WJ. Enhancement of triterpenoids production of Antrodia cinnamomea by co-culture with Saccharomyces cerevisiae. J Bioprocess Biotech. 2015;5(9):253.
  • Zheng WF, Zhao YX, Zheng X, et al. Production of antioxidant and antitumor metabolites by submerged cultures of Inonotus obliquus cocultured with Phellinus punctatus. Appl Microbiol Biotechnol. 2011;89(1):157–167.
  • Zou L, Sun T, Li D, et al. De novo transcriptome analysis of Inonotus baumii by RNA-seq. J Biosci Bioeng. 2016;121(4):380–384.
  • Chen CC, Chyau CC, Hseu TH. Production of a cox-2 inhibitor, 2,4,5-trimethoxybenzaldehyde, with submerged cultured Antrodia camphorata. Lett Appl Microbiol. 2007;44(4):387–392.
  • Shang CH, Zhu F, Li N, et al. Cloning and characterization of a gene encoding HMG-CoA reductase from Ganoderma lucidum and its functional identification in yeast . Biosci Biotechnol Biochem. 2008;72(5):1333–1339.
  • Yuan XL, Xiao ZY, Chne LY, et al. Cloning and expression analysis of 3-hydroxy-3-methylglutaryl coenzyme a reductase gene in Antrodia camphorata (AcHMGR). Genomics Appl Biol. 2018;37(1):358–365.
  • Haralampidis K, Trojanowska M, Osbourn AE. Biosynthesis of triterpenoid saponins in plants, in history and trends in bioprocessing and biotransformation. Adv Biochem Eng Biotechnol. 2002;75(2):31–49.
  • Lee MH, Jeong JH, Seo JW, et al. Enhanced triterpene and phytosterol biosynthesis in Panax ginseng overexpressing squalene synthase gene. Plant Cell Physiol. 2004;45(8):976–984.
  • Kim TD, Han JY, Huh GH, et al. Expression and functional characterization of three squalene synthase genes associated with saponin biosynthesis in Panax ginseng. Plant Cell Physiol. 2011;52(1):125–137.
  • Agger S, Lopez-Gallego F, Schmidt-Dannert C. Diversity of sesquiterpene synthases in the basidiomycete Coprinus cinereus. Mol Microbiol. 2009;72(5):1181–1195.
  • Wawrzyn GT, Bloch SE, Schmidt-Dannert C. Discovery and characterization of terpenoid biosynthetic pathways of fungi. Methods Enzymol. 2012;515(3):83–105.
  • Ichinose H, Kitaoka T. Insight into metabolic diversity of the brown-rot basidiomycete Postia placenta responsible for sesquiterpene biosynthesis: semi-comprehensive screening of cytochrome P450 monooxygenase involved in protoilludene metabolism. Microb Biotechnol. 2018;11(5):952–965.
  • Lee SY, Kim M, Kim SH, et al. Transcriptomic analysis of the white rot fungus Polyporus brumalis provides insight into sesquiterpene biosynthesis. Microbiol Res. 2016;182:141–149.