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Articles

Production of saponins from in vitro cultures of Astragalus glycyphyllos and their antineoplastic activity

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Pages 1413-1418 | Received 14 Jun 2019, Accepted 17 Sep 2019, Published online: 01 Oct 2019

References

  • Valev SA. Astragalus L. In: Yordanov D, editor. Flora republicae popularis bulgaricae. Sofia: Aedibus Academiae Scientiarum Bulgaricae; 1976. p. 167.
  • Nikolov SD, editor. Specialized encyclopedia of medicinal plants in Bulgaria. Sofia: Labour Publishing House; 2006.
  • Krasteva I, Shkondrov A, Ionkova I. Advances in phytochemistry, pharmacology and biotechnology of Bulgarian Astragalus species. Phytochem Rev. 2016;15(4):567–590.
  • Ionkova I, Shkondrov A, Krasteva I, et al. Recent progress in phytochemistry, pharmacology and biotechnology of Astragalus saponins. Phytochem Rev. 2014;13(2):343–374.
  • Linnek J, Mitaine-Offer AC, Miyamoto T, et al. Two cycloartane-type glycosides from the roots of Astragalus glycyphyllos. Planta Med. 2008;74(09):PB141.
  • Shkondrov A, Krasteva I, Bucar F, et al. A new tetracyclic saponin from Astragalus glycyphyllos L. and its neuroprotective and hMAO-B inhibiting activity. Nat Prod Res. 1. 2018. DOI 10.1080/14786419.2018.1491040
  • Elenga PA, Nikolov S, Panova D. Triterpene glycosides from Astragalus glycyphyllos L. - a new natural compound of the overground parts. Pharmazie. 1987;42:422–423.
  • Elenga PA, Nikolov S, Panova D. Triterpene glycosides and sterols from Astragalus glycyphyllos L. Pharmazie. 1986;41:41–42.
  • Lacaille-Dubois MA. Saponins as immunoadjuvants and immunostimulants In: Wagner H, editor. Immunomodulatory agents from plants. Basel: Springer; 1999. p. 243–272.
  • Jung Y, Jerng U, Lee S. A systematic review of anticancer effects of Radix Astragali. Chin J Integr Med. 2016;22(3):225–236.
  • Momekov G, Krasteva I, Platikanov S, et al. Cytotoxic activity of volatiles from four Astragalus species. C R Acad Bulg Sci. 2007;60:1023–1026.
  • Ionkova I. Astragalus species (milk vetch): In vitro culture and the production of saponins, astragaline, and other biologically active compounds In: Bajaj PS, editor. Biotechnology in agriculture and forestry 33. Medicinal and aromatic plants VIII. Berlin: Springer; 1995. p. 97–138.
  • Ionkova I. Pharmaceutically significant biologically active compounds from sources with optimized phyto-chemical potential [doctor of science]. Sofia: Medical University; 2007.
  • Raskin I. Plants and pharmaceuticals in the 21st century In: Vasil IK, editor. Plant biotechnology 2002 and beyond. Heidelberg: Springer; 2003. p. 83–95.
  • Alfermann AW, Petersen M. Natural product formation by plant cell biotechnology. Plant Cell Tiss Organ Cult. 1995;43(2):199–205.
  • Cragg GM, Newman DJ. Natural products: A continuing source of novel drug leads. Biochim Biophys Acta-Gen Subj. 2013;1830(6):3670–3695.
  • Verpoorte R. Pharmacognosy in the new millennium: leadfinding and biotechnology. J Pharm Pharmacol. 2000;52(3):253–262.
  • Murashige T, Skoog F. A revised medium for rapid growth and bio assays with tobacco tissue cultures. Physiol Plant. 1962;15(3):473–497.
  • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65(1-2):55–63.
  • Konstantinov SM, Eibl H, Berger MR. BCR-ABL influences the antileukaemic efficacy of alkylphosphocholines. Br J Haematol. 1999;107(2):365–374.
  • Yosifov DY, Kaloyanov KA, Guenova ML, et al. Alkylphosphocholines and curcumin induce programmed cell death in cutaneous T-cell lymphoma cell lines. Leuk Res. 2014;38(1):49–56.
  • Al Sharif M, Alov P, Diukendjieva A, et al. Molecular determinants of PPARγ partial agonism and related in silico/in vivo studies of natural saponins as potential type 2 diabetes modulators. Food Chem Toxicol. 2018;112:47–59.
  • Swartz ME, Krull IS. Analytical method development and validation. New York: CRC Press. 2018.
  • Dineva I, Krasteva I, Berger M, et al. In vitro antineoplastic activity of some cytoreductive drugs versus new compounds of plant origin. Int J Curr Chem. 2010;1:281–290.
  • Krasteva I, Momekov G, Zdraveva P, et al. Antiproliferative effects of a flavonoid and saponins from Astragalus hamosus against human tumor cell lines. Pharmacogn Mag. 2008;4:269–272.
  • Abbas F, Zayed R. Bioactive saponins from Astragalus suberi L. growing in Yemen. Z Naturforsch, C, J Biosci. 2005;60(11-12):813–820.
  • Tin MMY, Cho C-H, Chan K, et al. Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft. Carcinogenesis. 2007;28(6):1347–1355.
  • Auyeung K, Cho C, Ko J. A novel anticancer effect of Astragalus saponins: transcriptional activation of NSAID-activated gene. Int J Cancer. 2009;125(5):1082–1091.
  • Auyeung K, Law P, Ko J. Astragalus saponins induce apoptosis via an ERK-independent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line. Int J Mol Med. 2009;23(2):189–196.
  • Auyeung K, Woo P, Law P, et al. Astragalus saponins modulate cell invasiveness and angiogenesis in human gastric adenocarcinoma cells. J Ethnopharmacol. 2012;141(2):635–641.