1,023
Views
5
CrossRef citations to date
0
Altmetric
Articles

Hepato-, neuroprotective effects and QSAR studies on flavoalkaloids and flavonoids from Astragalus monspessulanus

, , , &
Pages 1434-1443 | Received 15 Jul 2019, Accepted 24 Sep 2019, Published online: 04 Oct 2019

References

  • Bratkov VM, Shkondrov AM, Zdraveva PK, et al. Flavonoids from the genus Astragalus: phytochemistry and biological activity. Pharmacogn Rev. 2016;10:11–32.
  • Khadem S, Marles RJ. Chromone and flavonoid alkaloids: occurrence and bioactivity. Molecules. 2011;17(1):191–206.
  • Simeonova R, Bratkov V, Kondeva-Burdina M, et al. Experimental liver protection of n-butanolic extract of Astragalus monspessulanus L. on carbon tetrachloride model of toxicity in rat. Redox Rep. 2015;20(4):145–153.
  • Krasteva I, Bratkov V, Bucar F, et al. Flavoalkaloids and flavonoids from Astragalus monspessulanus. J Nat Prod. 2015;78(11):2565–2571.
  • Kondeva-Burdina M, Krasteva I, Mitcheva M. Effects of rhamnocitrin 4-β-D-galactopyranoside, isolated from Astragalus hamosus on toxicity models in vitro. Pharmacog Mag. 2014;10:487–493.
  • Takayama F, Egashira T, Yamanaka Y. Protective effect of Ninjin-yoei-to on damage to isolated hepatocytes following transient exposure to tert-butyl hydroperoxide. Jpn J Pharmacol. 2001;85(3):227–233.
  • Taupin P, Zini S, Cesselin F, et al. Subcellular fractionation on Percoll gradient of mossy fiber synaptosomes: morphological and biochemical characterization in control and degranulated rat hippocampus. J Neurochem. 2008;62(4):1586–1595.
  • Lowry OH, Rosebrough NJ, Farr AL, et al. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193(1):265–275.
  • Mungarro-Menchaca X, Ferrera P, Moran J, et al. Beta-amyloid peptide induces ultrastructural changes in synaptosomes and potentiates mitochondrial dysfunction in the presence of ryanodine. J Neurosci Res. 2002;68(1):89–96.
  • Robyt JF, Ackerman RJ, Chittenden CG. Reaction of protein disulfide groups with Ellman's reagent: a case study of the number of sulfhydryl and disulfide groups in Aspergillus oryzae – amylase, papain, and lysozyme. Arch Biochem Biophys. 1971;147(1):262–269.
  • Drahota Z, Krivakova P, Cervinkova Z, et al. tert-Butyl hydroperoxide selectively inhibits mitochondrial respiratory-chain enzymes in isolated rat hepatocytes. Physiol Res. 2005;54(1):67–72.
  • Sridar C, Goosen TC, Kent UM, et al. Silybin inactivates cytochromes P450 3A4 and 2C9 and inhibits major hepatic glucuronosyltransferases. Drug Metab Dispos. 2004;32(6):587–594.
  • Nijveldt RJ, Nood E, Hoorn DEC, et al. Flavonoids: a review of probable mechanisms of action and potential applications. Am J Clin Nutr. 2001;74(4):418–425.
  • Stokes AH, Freeman WM, Mitchell SG, et al. Induction of GADD45 and GADD153 in neuroblastoma cells by dopamine-induced toxicity. Neurotoxicology. 2002;23(6):675–684.
  • Mitcheva M, Kondeva-Burdina M, Krasteva I, et al. Protective effect of purified saponin mixture from Astragalus corniculatus on toxicity models in vitro In: Tonev S, Kanev K, Dishovsky C, editors. Medical management of chemical and biological casualties. Sofia (S): Publishing House IRITA; 2009. p. 239–251.
  • Zhang G, Fang H, Li Y, et al. Neuroprotective effect of Astragalus polysacharin on streptozotocin (STZ)-induced diabetic rats. Med Sci Monit. 2019;25:135–141.
  • Hao M, Liu Y, Chen P, et al. Astragaloside IV protects RGC-5 cells against oxidative stress. Neural Regen Res. 2018;13:1081–1086.
  • Costa IM, Lima FOV, Fernandes LCB, et al. Astragaloside IV supplementation promotes a neuroprotective effect in experimental models of neurological disorders: a systematic review. Curr Neuropharmacol. 2019;17(7):648–665.