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Biotechnology & Biotechnological Equipment Volume 34, 2020 - Issue 1
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Research Article

Human umbilical cord mesenchymal stem cells suppress lung cancer via TLR4/NF-κB signalling pathway

Lu LiRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaView further author information
,
Jiongwei PanRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaView further author information
,
Xiaoping CaiRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaView further author information
,
Enhui GongRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaView further author information
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Cunlai XuRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaView further author information
,
Hao ZhengRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaView further author information
,
Zhuo CaoRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-7192-1294View further author information
ORCID Icon &
Zhangyong YinRespiratory Department, Lishui People’s Hospital, Lishui, P.R. ChinaCorrespondence[email protected]
View further author information
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Pages 24-29 | Received 19 Aug 2019, Accepted 02 Jan 2020, Published online: 13 Jan 2020

References

  • Michels S, Wolf J. Stratified treatment in lung cancer. Oncol Res Treat. 2016;39(12):760–766.
  • Siegel RL, Miller KD, Jemal A. Cancer statistics, 2017. CA: a cancer journal for clinicians. 2017;67(1):7–30.
  • Woodard GA, Jones KD, Jablons DM. Lung cancer staging and prognosis. Cancer Treat Res. 2016;170:47–75.
  • Abbaspanah B, Momeni M, Ebrahimi M, et al. Advances in perinatal stem cells research: a precious cell source for clinical applications. Regen Med. 2018 ;13(5):595–610.
  • Bieback K, Brinkmann I. Mesenchymal stromal cells from human perinatal tissues: From biology to cell therapy. World J Stem Cells. 2010; 2(4):81–92.
  • Choi SA, Lee JY, Wang KC, et al. Human adipose tissue-derived mesenchymal stem cells: characteristics and therapeutic potential as cellular vehicles for prodrug gene therapy against brainstem gliomas. Eur J Cancer (Oxford, England: 1990). 2012;48(1):129–137.
  • Mader EK, Butler G, Dowdy SC, et al. Optimizing patient derived mesenchymal stem cells as virus carriers for a Phase I clinical trial in ovarian cancer. J Transl Med. 2013;11(1):20–20.
  • Lamrani M, Sassi N, Paul C, et al. TLR4/IFNgamma pathways induce tumor regression via NOS II-dependent NO and ROS production in murine breast cancer models. Oncoimmunology 2016; May5(5):e1123369.
  • Yang Z, Zhu L, Li F, et al. Bone marrow stromal cells as a therapeutic treatment for ischemic stroke. Neurosci Bull. 2014;30(3):524–534.
  • Zhao H, Yao Y, Yang H, et al. Hormone therapy as a management strategy for lung metastasis after 5 years of endometrial cancer: A case report and literature review. Medicine 2017;96(51):e9223.
  • Ferrari SM, Fallahi P, Galdiero MR, et al. Immune and Inflammatory Cells in Thyroid Cancer Microenvironment. Int J Mol Sci 2019;20(18): E4413.
  • Schöniger S, Böttcher D, Theuß T, et al. Expression of Toll-like receptors 2, 4 and 6 in equine endometrial epithelial cells: A comparative in situ and in vitro study. Res Vet Sci. 2017;112:34–41.
  • Leng L, Wang Y, He N, et al. Molecular imaging for assessment of mesenchymal stem cells mediated breast cancer therapy. Biomaterials 2014;35(19):5162–5170.
  • Zhao W, Ren G, Zhang L, et al. Efficacy of mesenchymal stem cells derived from human adipose tissue in inhibition of hepatocellular carcinoma cells in vitro. Cancer Biother Radio. 2012;27(9):606–613.
  • Yulyana Y, Ho IA, Sia KC, et al. Paracrine factors of human fetal MSCs inhibit liver cancer growth through reduced activation of IGF-1R/PI3K/Akt signaling. Molec Ther. 2015;23(4):746–756.
  • Mills JT, Schwenzer A, Marsh EK, et al. Airway epithelial cells generate pro-inflammatory tenascin-C and small extracellular vesicles in response to TLR3 stimuli and rhinovirus infection. Front Immunol 2019;10:1987.
  • Lewandowska-Polak A, Brauncajs M, Jarzębska M, et al. Toll-like receptor agonists modulate wound regeneration in airway epithelial cells. Int J Mol Sci 2018; 19(8): E2456.
  • Gowing SD, Chow SC, Cools-Lartigue JJ, et al. Gram-negative pneumonia augments non-small cell lung cancer metastasis through host toll-like receptor 4 activation. J Thorac Oncol 2019;S1556-0864(19):30653–30657.
  • Yu L, Chen S. Toll-like receptors expressed in tumor cells: targets for therapy. Cancer Immunol Immunother. 2008;57(9):1271–1278.
  • Cherfils-Vicini J, Platonova S, Gillard M, et al. Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance. J Clin Invest. 2010;120(4):1285–1297.

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