Quercetin affects membrane lipids and apoptosis in three-dimensional fibroblast cultures

References

• Saito K. Possible site of flavonoid synthesis in the photosynthetic apparatus. Biochem J. 1974;144(2):431–432.
   PubMed Web of Science ®Google Scholar
• Filip R, López P, Giberti G, et al. Phenolic compounds in seven South American Ilex species. Fitoterapia. 2001;72(7):774–778.
   PubMed Web of Science ®Google Scholar
• Gugliucci A, Stahl AJ. Low density lipoprotein oxidation is inhibited by extracts of Ilex paraguariensis. Biochem Mol Biol Int. 1995;35(1):47–56.
   PubMedGoogle Scholar
• Viña J, Borras C, Abdelaziz KM, et al. The free radical theory of aging revisited: the cell signaling disruption theory of aging. Antioxid Redox Signal. 2013;19(8):779–787.
   PubMed Web of Science ®Google Scholar
• Packer L, Cadenas E. Oxidants and antioxidants revisited. New concepts of oxidative stress. Free Radic Res. 2007;41(9):951–952.
   PubMed Web of Science ®Google Scholar
• Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol. 2008;585(2-3):325–337.
   PubMed Web of Science ®Google Scholar
• Rice-Evans CA, Miller NJ, Paganga G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic Biol Med. 1996;20(7):933–956.
   PubMed Web of Science ®Google Scholar
• Lupanova T, Stefanova N, Petkova D, et al. Alterations in the content and physiological role of sphingomyelin in plasma membranes of cells cultured in three-dimensional matrix. Mol Cell Biochem. 2010;340(1-2):215–222.
   PubMed Web of Science ®Google Scholar
• Cukierman E, Pankov R, Stevens DR, et al. Taking cell-matrix adhesions to the third dimension. Science. 2001;294(5547):1708–1712.
   PubMed Web of Science ®Google Scholar
• Stefanova N, Staneva G, Petkova D, et al. Cell culturing in a three-dimensional matrix affects the localization and properties of plasma membrane cholesterol. Cell Biol Int. 2009;33(10):1079–1086.
   PubMed Web of Science ®Google Scholar
• Pankov R, Cukierman E, Clark K, et al. Specific β1 integrin site selectively regulates Akt/protein kinase B signaling via local activation of protein phosphatase 2A. J Biol. Chem. 2003; 278(20):18671–18681.
   PubMed Web of Science ®Google Scholar
• Skrobanska R, Evangelatov A, Stefanova N, et al. Cell proliferation in in vivo‐like three‐dimensional cell culture is regulated by sequestration of ERK 1/2 to lipid rafts. Cell Prolif. 2014; 47(4):336–346.
   PubMed Web of Science ®Google Scholar
• Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65(1):55–63.
   PubMed Web of Science ®Google Scholar
• Pankov R, Markovska T, Hazarosova R, et al. Cholesterol distribution in plasma membranes of beta1integrin-expressing and beta 1 integrin deficient fibroblasts. Arch Biochem Biophys. 2005;442(2):160–168.
   PubMed Web of Science ®Google Scholar
• Bligh E, Dyer W. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37(8):911–917.
   PubMedGoogle Scholar
• Touchstone J. Thin-layer chromatographic procedures for lipid separation. J Chromatogr. 1995;671(1-2):169–195.
   Web of Science ®Google Scholar
• Kahovcov J, Odavi R. A simple method for analysis of phospholipids separated on thin layer chromatography. J Chromatogr. 1969;40(1):90–96.
   PubMed Web of Science ®Google Scholar
• Morrison WR, Smith LM. Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride-methanol. J Lipid Res. 1964;5(4):600–608.
   PubMed Web of Science ®Google Scholar
• Koumanov K, Momchilova A, Quinn P, et al. Ceramides increase the activity of secretory phospholipase A2 and alter its fatty acid specificity. Biochem J. 2002;363(1):45–51.
   PubMed Web of Science ®Google Scholar
• Tsujishita Y, Asaoka Y, Nishizuka Y. Regulation of phospholipase A2 in human leukemia cell lines: its implication for intracellular signaling. Proc Natl Acad Sci USA. 1994;91(14):6274–6278.
   PubMed Web of Science ®Google Scholar
• Carini M, Aldini G, Piccone M, et al. Fluorescent probes as markers of oxidative stress in keratinocyte cell lines following UVB exposure. Farmaco. 2000;55(8):526–534.
   PubMedGoogle Scholar
• Ellman G. Tissue sulfhydryl groups. Arch Biochem Biophys. 1959;82(1):70–77.
   PubMed Web of Science ®Google Scholar
• Moore N, Patzer E, Barenholz Y, et al. Effect of phospholipase C and cholesterol oxidase on membrane integrity, microviscosity and infectivity of vesicular stomatitis virus. Biochemistry. 1977;16(21):4708–4715.
   PubMed Web of Science ®Google Scholar
• Bradford M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976;72:248–254.
   PubMed Web of Science ®Google Scholar
• Pugazhenthi S, Nesterova A, Sable C, et al. Akt/protein kinase B up-regulates Bcl-2 expression through cAMP-response element-binding protein. J Biol. Chem. 2000;275(15):10761–10766.
   PubMed Web of Science ®Google Scholar
• Brito AF, Ribeiro M, Abrantes AM, et al. Quercetin in cancer treatment, alone or in combination with conventional therapeutics?Curr Med Chem. 2015;22(26):3025–3039. 10.2174/0929867322666150812145435
   PubMed Web of Science ®Google Scholar
• Six DA, Dennis EA. The expanding superfamily of phospholipase A(2) enzymes: classification and characterization. Biochim Biophys Acta. 2000;1488(1-2):1–19.
   PubMed Web of Science ®Google Scholar
• Kim HJ, Kim KS, Kim SH, et al. Induction of cellular senescence by secretory phospholipase A2 in human dermal fibroblasts through an ROS-mediated p53 pathway. J Gerontol A Biol Sci Med Sci. 2009;64(3):351–362.
   PubMed Web of Science ®Google Scholar
• Muralikrishna AR, Hatcher JF. Phospholipase A2, reactive oxygen species, and lipid peroxidation in cerebral ischemia. Free Radic Biol Med. 2006;40(3):376–387.
   PubMed Web of Science ®Google Scholar
• Zou Y, Kim DH, Jung KJ, et al. Lysophosphatidylcholine enhances oxidative stress via the 5-lipoxygenase pathway in rat aorta during aging. Rejuvenation Res. 2009; 12(1):15–24.
   PubMed Web of Science ®Google Scholar
• Chiou YL, Lin SR, Hu WP, et al. Quercetin modulates activities of Taiwan cobra phospholipase A2 via its effects on membrane structure and membrane-bound mode of phospholipase A2. J Biosci. 2012;37(2):277–287.
   PubMed Web of Science ®Google Scholar
• Cotrim CA, de Oliveira SC, Diz Filho EB, et al. Quercetin as an inhibitor of snake venom secretory phospholipase A2. Chem Biol Interact. 2011;189(1-2):9–16.
   PubMed Web of Science ®Google Scholar
• Brusselmans K, Vrolix R, Verhoeven G, et al. Induction of cancer cell apoptosis by flavonoids is associated with their ability to inhibit fatty acid synthase activity. J Biol Chem. 2005;280(7):5636–5645.
   PubMed Web of Science ®Google Scholar
• Chang YC, Lee TS, Chiang AN. Quercetin enhances ABCA1 expression and cholesterol efflux through a p38-dependent pathway in macrophages. J Lipid Res. 2012; 53(9):1840–1850.
   PubMed Web of Science ®Google Scholar
• Nekohashi M, Ogawa M, Ogihara T, et al. Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter Niemann-pick c1-like 1 in caco-2 cells and rats. PLoS One. 2014; 9(5):e97901.
   PubMed Web of Science ®Google Scholar
• Sargis RM, Subbaiah PV. Protection of membrane cholesterol by sphingomyelin against free radical-mediated oxidation. Free Radic Biol Med. 2006; 40(12):2092–2102.
   PubMed Web of Science ®Google Scholar
• Momchilova A, Petkova D, Staneva G, et al. Resveratrol alters the lipid composition, metabolism and peroxide level in senescent rat hepatocytes. Chem Biol Interact. 2014;207:74–80.
   PubMed Web of Science ®Google Scholar
• Prabu SM, Shagirtha K, Renugadevi J. Amelioration of cadmium-induced oxidative stress, impairment in lipids and plasma lipoproteins by the combined treatment with quercetin and α-tocopherol in rats. J Food Sci. 2010;75(7):132–140.
   PubMed Web of Science ®Google Scholar
• Surapaneni KM, Jainu M. Comparative effect of pioglitazone, quercetin and hydroxy citric acid on the status of lipid peroxidation and antioxidants in experimental non-alcoholic steatohepatitis. J Physiol Pharmacol. PMID:24622831. 2014;65(1):67–74.
   Google Scholar
• Jarosiewicz M, Krokosz A, Marczak A, et al. Changes in the activities of antioxidant enzymes and reduced glutathione level in human erythrocytes exposed to selected brominated flame retardants. Chemosphere. 2019;227:93–99.
   PubMed Web of Science ®Google Scholar