Platelet polymorphism rs5918T > C in the integrin B3 gene modulates comorbidities in patients with psoriasis

References

• Daugaard C, Iversen L, Hjuler KF. Comorbidity in adult psoriasis: considerations for the clinician. Psoriasis (Auckl). 2022;12:1–8.
   PubMedGoogle Scholar
• Oliveira MDFSPD, Rocha BDO, Duarte GV. Psoriasis: classical and emerging comorbidities. An Bras Dermatol. 2015;90(1):9–20. PMID: 25672294; PMCID: PMC4323693.
   PubMed Web of Science ®Google Scholar
• Hu SC, Lan CE. Psoriasis and cardiovascular comorbidities: focusing on severe vascular events, cardiovascular risk factors and implications for treatment. IJMS. 2017;18(10):2211. PMID: 29065479; PMCID: PMC
   Google Scholar
• Ahlehoff O, Gislason GH, Lindhardsen J, et al. Prognosis following first-time myocardial infarction in patients with psoriasis: a danishnationwide cohort study: psoriasis and prognosis following myocardial infarction. J Intern Med. 2011;270(3):237–244.
   PubMed Web of Science ®Google Scholar
• Langan SM, Seminara NM, Shin DB, et al. Prevalence of metabolic syndrome in patients with psoriasis: a population-based study in the United Kingdom. J Invest Dermatol. 2012;132(3 Pt 1):556–562.
   PubMed Web of Science ®Google Scholar
• Hao Y, Zhu Y, Zou S, et al. Metabolic syndrome and psoriasis: mechanisms and future directions. Front Immunol. 2021;12:711060.
   PubMed Web of Science ®Google Scholar
• Visser MJE, Tarr G, Pretorius E. Thrombosis in psoriasis: cutaneous cytokine production as a potential driving force of haemostatic dysregulation and subsequent cardiovascular risk. Front Immunol. 2021;12:688861. PMID: 34335591; PMCID: PMC8324086.
   PubMed Web of Science ®Google Scholar
• Vebman JI, Choy A, Yao C. Review of the prevalenceprevalence of cardiovascularcardiovascular and metabolic comorbiditiesmetabolic comorbidities of psoriasispsoriasis. J Skin. 2020;4(2):112–118.
   Google Scholar
• Hjuler K, Gormsen L, Vendelbo M, et al. Systemic inflammation and evidence of a cardio-splenic axis in patients with psoriasis. Acta Derm Venereol. 2018;98(4):390–395.
   PubMed Web of Science ®Google Scholar
• Capon F. The genetic basis of psoriasis. IJMS. 2017;18(12):2526. PMID: 29186830; PMCID: PMC5751129.
   Google Scholar
• Huang YH, Kuo CF, Huang LH, et al. Familial aggregation of psoriasis and co-aggregation of autoimmune diseases in affected families. JCM. 2019;8(1):115.
   Google Scholar
• Yang J, Ma Y-Q, Page RC, et al. Structure of an integrin αIIbβ3 transmembrane-cytoplasmic heterocomplex provides insight into integrin activation. Proc Natl Acad Sci USA. 2009;106(42):17729–17734.
   PubMed Web of Science ®Google Scholar
• Sosnoski DM, Emanuel BS, Hawkins AL, et al. Chromosomal localization of the genes for the vitronectin and fibronectin receptors alpha subunits and for platelet glycoproteins IIb and IIIa. J Clin Invest. 1988;81(6):1993–1998.
   PubMed Web of Science ®Google Scholar
• Wagner CL, Mascelli MA, Neblock DS, et al. Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets. Blood. 1996;88(3):907–914.
   PubMed Web of Science ®Google Scholar
• Di Castelnuovo A, de Gaetano G, Benedetta Donati M, et al. Platelet glycoprotein IIb/IIIa polymorphism and coronary artery disease: implications for clinical practice. Am J Pharmacogenomics. 2005;5(2):93–99.
   PubMedGoogle Scholar
• Goodall A, Curzen N, Panesar M, et al. Increased binding of fibrinogen to glycoprotein IIIa-Proline33 (HPA-1b, PlA2, zwb) positive platelets in patients with cardiovascular disease. Eur Heart J. 1999;20(10):742–747.
   PubMed Web of Science ®Google Scholar
• Galasso G, Santulli G, Piscione F, et al. The GPIIIA PlA2 polymorphism is associated with an increased risk of cardiovascular adverse events. BMC Cardiovasc Disord. 2010;10(1):41.
   PubMedGoogle Scholar
• Newman P, Derbes R, Aster R. The human platelet alloantigens, PlA1 and PlA2, are associated with a leucine33/proline33 amino acid polymorphism in membrane glycoprotein IIIa, and are distinguishable by DNA typing. J Clin Invest. 1989;83(5):1778–1781.
   PubMed Web of Science ®Google Scholar
• Walter DH, Schachinger V, Elsner M, et al. Platelet glycoprotein IIIa polymorphisms and risk of coronary stent thrombosis. Lancet. 1997;350(9086):1217–1219.
   PubMed Web of Science ®Google Scholar
• Ridker PM, Hennekens CH, Schmitz C, et al. PlA1/A2 polymorphism of platelet glycoprotein IIIa and risks of myocardial infarction, stroke, and venous thrombosis. Lancet. 1997;349(9049):385–3 88.
   PubMed Web of Science ®Google Scholar
• Floyd CN, Ellis BH, Ferro A. The PlA1/A2 polymorphism of glycoprotein IIIa as a risk factor for stroke: a systematic review and Meta-Analysis. PLoS One. 2014;9(7):e100239.
   PubMed Web of Science ®Google Scholar
• Wang J, Liu J, Zhou Y, et al. Association among PlA1/A2 gene polymorphism, laboratory aspirin resistance and clinical outcomes in patients with coronary artery disease: an updated meta-analysis. Sci Rep. 2019;9(1):13177.
   PubMedGoogle Scholar
• Clinical Review Report: Guselkumab (Tremfya): (Janssen Inc.): Indication: for the treatment of adult patients with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy. https://www.ncbi.nlm.nih.gov/books/NBK534046/#:∼:text=The%20PASI%20is%20a%20widely,over%2010%20is%20considered%20severe.
   Google Scholar
• StripAssay® Procedure Vienna Lab. https://www.viennalab.com/home/unterlagen/technical-notes/131-stripassay-manual-v1-2/file.
   Google Scholar
• https://gnomad.broadinstitute.org/variant/17-45360730-T-C?dataset=gnomad_r2_1. Last evaluated June 18, 2020.
   Google Scholar
• Bojesen S, Juul K, Schnohr P, et al. Platelet glycoprotein IIb/IIIa PlA2/PlA2homozygosity associated with risk of ischemic cardiovascular disease and myocardial infarction in young men. J Am Coll Cardiol. 2003;42(4):661–667.
   PubMed Web of Science ®Google Scholar
• Komsa-Penkova R, Dimitrov B, Tonchev P, et al. Place of MTHFR gene polymorphism C677T as a risk factor in obese male patients with psoriasis. Clin Nutr. 2020;40:431.
   Google Scholar
• Dimitrov B, Gospodinov D, Gincheva V, et al. Prevalence of MTHFR gene 677C > T polymorphism in the patients with psoriasis vulgaris. J IMAB. 2021;27(2):3707–3711.
   Web of Science ®Google Scholar
• Gelfand JM, Neimann AL, Shin DB, et al. Risk of myocardial infarction in patients with psoriasis. JAMA. 2006;296(14):1735–1741.
   PubMed Web of Science ®Google Scholar
• Pfrieger FW. Neurodegenerative diseases and cholesterol: seeing the field through the players. Front Aging Neurosci. 2021;13:766587.
   PubMed Web of Science ®Google Scholar
• Hajar Sharami S, Abbasi Ranjbar Z, Alizadeh F, et al. The relationship of hyperlipidemia with maternal and neonatal outcomes in pregnancy: a cross-sectional study. Int J Reprod Biomed. 2019;17(10):739–748. PMID: 31807722; PMCID: PMC6844284.
   PubMed Web of Science ®Google Scholar
• Goldschmidt-Clermont J, Coleman D, Pham M, et al. Higher prevalence of GPIIIa PlA2 polymorphism in siblings of patients with premature coronary heart disease. Arch Pathol Lab Med. 1999;123(12):1223–1229.
   PubMed Web of Science ®Google Scholar
• Floyd CN, Mustafa A, Ferro A. The PlA1/A2 polymorphism of glycoprotein IIIa as a risk factor for myocardial infarction: a meta-analysis. PLoS One. 2014;29(7):e101518. PMID: 24988220; PMCID: PMC4079717.
   PubMed Web of Science ®Google Scholar
• Mikkelsson J, Perola M, Kauppila LI, et al. The GPIIIa Pl(A) polymorphism in the progression of abdominal aortic atherosclerosis. Atherosclerosis. 1999;147(1):55–60. PMID: 10525125.
   PubMed Web of Science ®Google Scholar
• Kucharska-Newton AM, Monda KL, Campbell S, et al. Association of the platelet GPIIb/IIIa polymorphism with atherosclerotic plaque morphology: the atherosclerosis risk in communities (ARIC) study. Atherosclerosis. 2011;216(1):151–156.
   PubMed Web of Science ®Google Scholar
• Makredes M, Robinson D, Bala M, et al. The burden of autoimmune disease: a comparison of prevalence ratios in patients with psoriatic arthritis and psoriasis. J Am Acad Dermatol. 2009;61(3):405–410.
   PubMed Web of Science ®Google Scholar
• Wu JJ, Nguyen TU, Poon KYT, et al. The association of psoriasis with autoimmune diseases. J Am Acad Dermatol. 2012;67(5):924–930.
   PubMed Web of Science ®Google Scholar
• Daudén E, Castañeda S, Suárez C, et al. Clinical practice guideline for an integrated approach to comorbidity in patients with psoriasis:approach to comorbidity in psoriasis. J Eur Acad Dermatol Venereol. 2013;27(11):1387–1404.
   PubMed Web of Science ®Google Scholar
• Ahlehoff O, Skov L, Gislason G, et al. Pharmacological undertreatment of coronary risk factors in patients with psoriasis: observational study of the danish nationwide registries. PLoS One. 2012;7(4):e36342.
   PubMed Web of Science ®Google Scholar
• Pina-Cabral LB, Carvalhais V, Mesquita B, et al. Myocardial infarction before and after the age of 45: possible role of platelet receptor polymorphisms. Rev Port Cardiol. 2018;37(9):727–735.
   PubMedGoogle Scholar