References
- Vane J, Botting R. Inflammation and the mechanism of action of anti-inflammatory drugs. FASEB J 1987; 1: 89–96.
- Lands W E M. Actions of anti-inflammatory drugs. Trends Pharmacol 1981; 2: 78–80.
- Mehler E L, Gerhards J. Electronic determinants of the anti-inflammatory action of benzoic and salicylic acids. Mol Pharmacol 1987; 31: 284–293.
- Roth G J, Machuga E T, Ozols J. Isolation and covalent structure of the aspirin-modified, active-site region of prostaglandin synthase. Biochemistry 1983; 22: 4672–4675.
- Betts W H, Whitehouse M W, Cleland L G, Vernon-Roberts B. In vitro antioxidant properties of potential biotransformation products of salicylate, sulphalazine and amidopyrine. J Free Radic Biol Med 1985; 1: 273–280.
- Grootveld M, Halliwell B. Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Biochem J 1986; 237: 499–504.
- Ghiselli A, Laurenti O, Demattia G, Maiani G, Ferro-Luzz A. Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients. Free Radic Biol Med 1992; 13: 621–626.
- Powell S R, Hall D. Use of salicylate as a probe for OH; formation in isolated ischemic rat hearts. Free Radic Biol Med 1990; 9: 133–141.
- Udassin R, Ariel I, Haskel Y, Kitrossky N, Chevion M. Salicylate as in vivo free radical trap: studies on ischemic insult to the rat intestine. Free Radic Biol Med 1991; 10: 1–6.
- Cleland L G, Lowthian P J, Imhoff D, Bochner F, Betts W H. Plasma and synovial fluid gentisate in patients receiving salicylate therapy. J Rheumatol 1985; 12: 136–139.
- Maskos Z, Rush J D, Koppenol W H. The hydroxylation of the salicylate anion by a Fenton reaction and radiolysis: a consideration of the respective mechanisms. Free Radic Biol Med 1990; 8: 153–162.
- Moorhouse C P, Halliwell B, Grootveld M, Gutteridge J M C. Cobalt(II) ion as a promoter of hydroxyl radical and possible crypto-hydroxyl radical formation under physiological conditions. Differential effects of hydroxyl radical scavengers. Biochim Biophys Acta 1985; 843: 261–268.
- Grootveld M, Halliwell B. 2,3-dihydroxybenzoic acid is a product of human aspirin metabolism. Biochem Pharmacol 1988; 37: 271–280.
- Cleland L G, Whitehouse M W, Betts W H. Gentisate, a salicylic metabolite with antioxidant properties. Drugs Exp Clin Res 1985; 11: 463–467.
- Capelle S, Planckaert B, Cotelle P, Catteau J P. Hydroxyl radical scavenging activity of salicylic acid and its hydroxylated metabolites. An ESR study. J Chim Phys 1992; 89: 561–566.
- Mehler E L, Habicht J, Brune K. Quantum chemical analysis of structure activity relationships in nonsteroidal anti-inflammatory drugs. Mol Pharmacol 1982; 22: 525–528.
- Habicht J, Brune K. Inhibition of prostaglandin E2 release by salicylates, benzoates and phenols: a quantitative structure-activity study. J Pharm Pharmacol 1983; 35: 718–723.
- Capelle S, Pellegrini S, Cotelle P, Imbenotte M, Pommery J, Catteau J P. ESR characterization of the autoxidation products from gentisic acid. Application to humic model synthesis. Water Res (submitted).
- Oturan M A, Pinson J, Deprez D, Terlain B. Polyhydroxylation of salicylic acid by electrochemically generated OH radicals. New J Chem 1992; 16: 705–710.
- Mellors A, Tappel A L. The inhibition of mitochondrial peroxidation by ubiquinone and ubiquinol. J Biol Chem 1966; 241: 4353–4356.
- Gilman H, Thirtle J R. Dibenzofuran XXI: Benzene and biphenyl intermediates for 1,9-derivatives. J Am Chem Soc 1944; 66: 858–859.
- Kreuchunas A. The preparation of 2,3,5-trihydroxybenzoic acid. J Org Chem 1956; 21: 219.
- MacOmie J F W, Watts M L, West D E. Demethylation of aryl methyl ethers by boron tribromide. Tetrahedron 1968; 24: 2289–2292.
- Phillips H J. Dye exclusion tests for cell viability. In: Kruse PK, Patterson MK, eds. Tissue culture. New York: Academic Press, 1973: 406–408.
- Oehler U M, Janzen E G. Simulation of isotropic electron spin resonance spectra: a transportable basic program. Can J Chem 1982; 60: 1542–1548.
- Kubo K, Yoshitake I, Kumada Y, Shuto K, Nakamizo N. Radical scavenging action of flunarizine in rat brain in vitro. Arch Int Pharmacodyn Ther 1984; 272: 283–295.
- Bergglioni M, Wymann M P. Turning on the respiratory burst. Trends Biochem Sci 1990; 15: 69–72.