Heme oxygenase-1 mRNA levels, metallothionein mRNA levels, lipid peroxidation and microsomal CYP1A activities in rats treated with 3,3-dichlorobenzidine and some other inducers of P450

References

• Iba M, Lang B. Stimulation of the conjugation of lipid dienes in hepatic microsomes by 3,3′-dichlorobenzidine. Biochem Pharmacol 1988; 37: 781–791.
   PubMed Web of Science ®Google Scholar
• Iba M, Sikka H C. Induction of hepatic microsomal cytochromeP448- mediated oxidases by 3,3′-dichlorobenzidine in the rat. Biochem Pharmacol 1982; 32: 901–909.
   Web of Science ®Google Scholar
• Iba, M M and Thomas, P E, Activation of 3,3′-dichlorobenzidine in rat liver microsomes to mutagens: involvement of cytochrome P-450d. Carcinogenesis 1988; 9: 717–723.
   PubMed Web of Science ®Google Scholar
• IARC. Some industrial chemicals and dyestuffs. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man 1982; 29: 239–256.
   Google Scholar
• Kappus H. Lipid peroxidation: mechanisms, analysis, enzymology and biological relevance. In: Oxidative Stress (Sies H, ed.) 273–310. Academic Press, 1985.
   Google Scholar
• Sato M, Bremrner I. Oxygen free radicals and metallothionein. Free Radic Biol Med 1993; 14: 325–337.
   PubMed Web of Science ®Google Scholar
• Kyse S M, Tyrell R M. Heme oxygenase is the major 32-Kda stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proc Natl Acad Sci USA 1989; 86: 99–103.
   PubMed Web of Science ®Google Scholar
• Stocker R. Induction of heme oxygenase as a defense against oxidative stress. Free Radic Res Comrnun 1990; 9: 101–112.
   PubMed Web of Science ®Google Scholar
• Thornalley P J, Vasak M. Possible role of metallothionein in protection against radiation-induced oxidative stress. Kinetics and mechanism of its reaction with superoxide and hydroxyl radicals. Biochim Biophys Acta 1985; 827: 36–44.
   PubMed Web of Science ®Google Scholar
• Ma M, Eaton J W. Oxidative stress genes and proteins: fire alarms and fire extinguishers. In: Oxidative damage and Repair. Chemical, Biological and Medical Aspects (Davis K J A, ed.) 1–4. Pergamon Press, 1991.
   Google Scholar
• Stocker R, Yamamoto Y, McDonagh A F, Glazer A N, Ames B N. Bilirubin is an antioxidant of possible physiological significance. Science 1987; 235: 1043–1056.
   PubMed Web of Science ®Google Scholar
• Maines M D, Mayer R D, Ewing J F, McCoubrey W K Jr. Induction of Heme Oxygenase-1 (HSP32) mRNA and protein by ischemia/reperfusion: Possible role of heme as both promoter of tissue damage and regulator of HSP32. J Pharmacol Exp Ther 1993; 264: 457–462.
   PubMed Web of Science ®Google Scholar
• Kikuchi G, Yoshida T. Function and induction of the microsomal heme oxygenase. Mol Cell Biochem 1983; 53/54: 163–183.
   PubMed Web of Science ®Google Scholar
• Lu A Y H, Jacobson M, Poyer J L, McCay P B. Lipid peroxidation and the degradation of cytochrome P-450 heme. Arch Biochem Biophys 1973; 158: 842–852.
   PubMed Web of Science ®Google Scholar
• Raunio H, Vahakangas K, Saarni H, Pelkonen O. Effects of cigarette smoke on rat lung and liver ornithine decarboxylase and aryl hydrocarbon hydroxylase activities and lung benzo(a)pyrene metabolism. Acta Pharmacol ToxicoL 1983; 52: 168–174.
   PubMedGoogle Scholar
• Chomczynski P, Sacchi A. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Bicohem 1987; 162: 156–159.
   PubMed Web of Science ®Google Scholar
• Guzelian P S, Elshourbagy N A. Induction of hepatic heme oxygenase activity by bromobenzene. Arch Biochem Biophys 1979; 196: 178–185.
   PubMed Web of Science ®Google Scholar
• Pohl R J, Fouts J R. A rapid method for assaying the metabolism 7-ethoxyresorufin by microsomal cellular fractions. Anal Biochem 1980; 107: 150–155.
   PubMed Web of Science ®Google Scholar
• Dehnen W, Tomingas R, Roos J A. Modified method for the assay of benzo(a)pyrene hydroxylase. Anal Biochem 1973; 53: 373–383.
   PubMed Web of Science ®Google Scholar
• Iba M M. Effect of acute 3,3′-dichlorobenzidine administration on rat hepatic enzymic and nonenzymatic microsomal lipid peroxidation and antioxidant status. Res Commun Chem Pathol Pharmacol 1987; 56: 243–251.
   PubMed Web of Science ®Google Scholar
• Alam J, Shibahara S, and Smith A. Transcriptional activation of the heme oxygenase gene by heme and cadmium in mouse hepatoma cells. J Biol Chem 1989; 264: 6371–6375.
   PubMed Web of Science ®Google Scholar
• Alam J, and Smith A. Heme-hemopexin-mediated induction of metallothionein in gene expression. J Biol Chem 1992; 267: 16379–16384.
   PubMed Web of Science ®Google Scholar
• Griffith O W. Determination of glutathione disulfide using glutathione reductase and 2-vinylpyridine. Anal Biochrem 1980; 186: 207–212.
   Google Scholar
• Omura T, Sato R. The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J Biol Chem 1964; 239: 2370–2378.
   PubMed Web of Science ®Google Scholar
• Lowry O H, Rosebrough N J, Farr A L, Randall R J. Protein measurement with the Folin phenol reagent. J Biol Chem 1961; 193: 256–275.
   Google Scholar
• Ryan D E, Levin W. Purification and characterization of hepatic microsomal cytochrome P-450. Pharmacol Ther 1990; 45: 153–239.
   PubMed Web of Science ®Google Scholar
• Roberts E A, Xie Z W, Yang S, Lipa J. Inducibility of enzyme activities associated with the cytochrome P-450 1A family, ethoxyresorufin O-deethylase and methoxyresorufin O-demethylase in human hepatocyte lines derived from normal liver tissue. Drug Metab Dispos 1993; 21: 56–61.
   PubMed Web of Science ®Google Scholar
• Yang H-Y L, Namkung M J, Juchau M R. Cytochrome P450-dependent biotransformation of a series of phenoaxazone ethers in the rat conceptus during early organogenesis: evidence of multiple P-450 isozymes. Mol Pharmacol 1988; 349: 67–73.
   Google Scholar
• Min K-S, Terano Y, Onosaka A, Tanaka A. Induction of metallothionein synthesis by menadione and carbon tetrachloride is independent of free radical production. Toxicol Appl Pharmacol 1992; 113: 74–79.
   PubMed Web of Science ®Google Scholar
• Kuty K R, Daniel R F, Ryan D E, Levin W, Maines M D. Rat liver cytochrome P-450b, P-420b, and P-420c are degraded to biliverdin by heme oxygenase. Arch Biochem Biophys 1988; 260: 638–644.
   PubMed Web of Science ®Google Scholar
• Schwartzman M L, Stoltz R A, Conners M S, Abraham N G. Cytochrome P450 arachidonate metabolites are mediators of the inflammatory response in the cornea. Abstracts, 10th International Symposium on Microsomes and Drug Oxidations, University of Toronto, Canada, July 18–21, 1994; 533.
   Google Scholar
• Tomaro M L, Frydman J, Frydman R B. Heme oxygenase induction by CoC12, Co-protoporphyrin IX, phenylhydrazine, and diamide: evidence for oxidative stress involvement. Arch Biochem Biophys 1991; 286: 610–617.
   PubMed Web of Science ®Google Scholar
• Ariyoshi T, Hasegawa H, Matsumoto H, Arizona K. Effects of surfactants on the contents of metallothionein, heme and hemoproteins and on the activities of heme oxygenase and drug-metabolizing enzymes in rats pretreated with phenobarbital or β-naphthoflavone. Bull Environ Contam Toxicol 1991; 46: 120–127.
   PubMed Web of Science ®Google Scholar
• Eaton D L, Stacey N H, Wong K-L and Klassen CD. Dose-response effects of various metal ions on rat liver metallothionein, glutathione, heme oxygenase, and cytochrome P-450. Toxicol Appl Pharmacol 1989; 55: 393–402.
   Google Scholar
• Oguro T, Yoshida T, Numazawa S, Kuroiwa Y. Possible role of glutathione depletion in the induction of rate-limiting enzymes involved in heme degradation and polyamine biosynthesis in the liver of rats. J Pharmacobio Dyn 1990; 13: 628–636.
   PubMedGoogle Scholar
• Abraham N G, Lutton J D, Freedman M L, Levere R D. Benzene modulation of liver cell structure and heme-cytochrome P-450 metabolism. Am J Med Sci 1986; 292: 81–86.
   PubMed Web of Science ®Google Scholar
• Okuno F, Arai M, Sujita K, Eto M, Ishi H. Alterations in Hepatic δ-aminolevulinic acid synthetase and heme oxygenase activities after chronic ethanol consumption in rats. Alcohol 1991; 8: 449–451.
   PubMed Web of Science ®Google Scholar
• Lincoln BC, Healy J F, Bonkovsky H L. Regulation of hepatic haem metabolism. Disparate mechanisms of induction of haem oxygenase by drugs and metals. Biochem J 1988; 250: 189–196.
   PubMed Web of Science ®Google Scholar
• Iba M, Poyer J L, Downs P, Massion W H. In vivo spin-trapping of the radical metabolites of 3,3′-dichloro-benzidine and related compounds in the rat. Prog Pharmacol Clin Pharmacol 1991; 8: 255–266.
   Google Scholar
• Moore M R, McColl K E L, Rimington C and Goldberg A. Drugs, chemicals and porphyria. In: Disorders of porphyrin metabolism. Plenium Publishing Corp., New York 1987: 139–165.
   Google Scholar
• Lautier D, Luscher P, Tyrell R M. Endogenous glutathione levels modulate both constitutive and UVA radiation/hydrogen peroxide inducible expression of the human heme oxygenase gene. Carcinogenesis 1992; 13: 227–232.
   PubMed Web of Science ®Google Scholar