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Redox Report
Communications in Free Radical Research
Volume 3, 1997 - Issue 3
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Original Articles

Combined effect of 3-aminobenzamide and N-acetylcysteine on HIV replication in chronically infected U937 cells

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Pages 145-151 | Received 03 Feb 1997, Accepted 28 May 1997, Published online: 13 Jul 2016

REFERENCES

  • Ho D, Neumann A, Perelson A, Chen W, Lonard J, Markowitz M. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 1995; 373: 123–126.
  • Osbron L, Kunkel S, Nabel G U. Tumor necrosis factor and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor κB. Proc Natl Acad Sci USA 1989; 86: 2336–2340.
  • Schreck R, Rieber P, Baeuerle P A. Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF-κB transcription factor and HIV-1. EMBO J 1991; 10: 2247–2258.
  • Buhl R, Holyroyd K J, Mastrangeli A et al. Systemic glutathione deficiency in symptom-free HIV-seropositive individuals. Lancet 1989; 2: 1294–1297.
  • Larrick J W, Wright S C. Cytotoxic mechanism of tumor necrosis factor-α FASEB J 1990; 4: 3215–3223.
  • Ameisen J C. Programmed cell death and AIDS: from hypothesis to experiment. Immunol Today 1992; 13: 388–39?
  • Gougeon M L, Montagnier L. Apoptosis in AIDS. Science 1993; 260: 1269–1270.
  • Wyllie A H. Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation. Nature 1980; 284: 555–556.
  • Williams G T, Smith C A, McCarthy N J, Grimes E A. Apoptosis: final point in cell biology. Trends Cell Biol 1992; 2: 263–267.
  • Malorni W, Donelli G. Cell death: general features and morphological aspects. Ann NY Acad Sci 1992; 663: 218–233.
  • Kroemer G, Petit P, Zamzami N, Vayssiere J L, Mignotte B. The biochemistry of programmed cell death. FASEB J 1995; 9: 1277–1287
  • Savill J, Fadok N, Henson P, Haslett C. Phagocyte recognition of cells undergoing apoptosis. Immunol Today 1993; 14: 131–136.
  • Osborn B A, Schwartz L M. Essential genes that regulate apoptosis. Trends Cell Biol 1994; 4: 394–399.
  • Farzaneh F, Zalin R, Brill D, Shall S. DNA strand breaks and ADP-ribosyl transferases activation during cell differentiation. Nature 1982; 300: 362–366.
  • Carson D A, Seto S, Wasson D B, Carrera C J. DNA strand breaks, NAD metabolism, and programmed cell death. Exp Cell Res 1986; 164: 273–281.
  • Agarwal S S, Drysdale B E, Shin H S. Tumor necrosis factor mediated cytotoxicity involves ADP-ribosylation. J Immunol 1988; 140: 4187–4192.
  • Malorni W, Rivabene R, Santini M T, Donelli G. N-acetylcysteine inhibits apoptosis and decreases viral particles in HIV-chronically infected U937 cells. FEBS Lett 1993; 327: 75–78.
  • Malorni W, Rainaldi G, Straface E et al. 3-aminobenzamide induces cytoskeleton rearrangement in M14 cells. Biochem Biophys Res Comm 1994; 202: 915–922.
  • Locardi C, Petrini C, Boccoli G et al. Increased human immunodeficiency virus (HIV) expression in chronically infected U937 cells upon in vitro differentiation by hydroxyvitamin D3: roles of interferon and tumor necrosis factor in regulation of HIV production. J Virol 1990; 64: 5874–5882.
  • Bursch W, Oberhammer F, Schulte-Hemann R. Cell death by apoptosis and its protective role against disease. Trends Pharmacol Sci 1992; 13: 245–251.
  • Andree H A M, Reutelingsperger C P M, Hauptmann R et al. Binding of vascular anticoagulant α (VACα) to planar phospholipids bilayers. J Biol Chem 1990; 265: 4923–4928.
  • Cleaver J E, Borek C, Milam K, Morgan W F. The role of poly(ADP ribose) synthesis in toxicity and repair of DNA damage. Pharmacol Therap 1987; 31: 269–272.
  • Marini M, Zunica G, Tamba M et al. Recovery of human lymphocytes damaged with γ-radiation or enzymatically produced oxygen radicals: different effects of poly(ADP- ribosyl) polymerase inhibitors. Int J Rad Biol 1990; 58: 279–291.
  • Monti D, Troiano L, Tropea F et al. Apoptosis-programmed cell death: a role in the aging process? Am J Clin Nutr 1992; 55: 1208–1214.
  • Cossarizza A, Franceschi C, Monti D et al. Protective effect of N-acetylcysteine in Tumor Necrosis Factor α-induced apoptosis in U937 cells: the role of mitochondria. Exp Cell Res 1995; 220: 232–240.
  • Peng H B, Libby P, Liao J K. Induction and stabilization of I kappa B alpha by nitric oxide mediates inhibition of NK-kappa B. J Biol Chem 1995; 270: 14214–14219.
  • Prochaska H J, Chavan S J, Baron P, Polsky B J. Oltipratz, a novel inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. J Cell Biochem Suppl 1995; 22: 117–125.
  • Malorni W, Rivabene R, Santini M T et al. TNF-induced mitochondrial damage, apoptosis and viral particle production: their prevention by N-acetylcysteine in HIV-chronically infected U937 cells. Redox Report 1994; 1: 57–64.
  • Malorni W, Rivabene R, Straface et al. 3-aminobenzamide protects from UV-B-induced apoptosis by acting on cytoskeleton and substrate adhesion. Biochem Biophys Res Comm 1995; 207: 715–724.
  • Durkacz B W, Lunec J, Grindley H et al. Murine melanoma cells differentiation and melanogenesis induced by poly(ADP-ribose) polymerase inhibitors. Exp Cell Res 1992; 202: 287–291.
  • Rankin P W, Jacobson E L, Benjamin R C et al. Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo. J Biol Chem 1989; 264: 4312–4317.
  • Rivabene R, Viora M, Matarrese P et al. N-acetyl-cysteine enhances cell adhesion properties of epithelial and lymphoid cells. Cell Biol Internat 1995; 19: 681–686.
  • Ridley A J, Hall A. The small GTP-binding protein rho regulates the assembly of focal adhesion and actin stress fibers in response to growth factors. Cell 1992; 70: 389–399.
  • Raju P A, Herzenberg L A, Roederer M. Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication. AIDS Res Hum Retroviruses 1994; 10: 961–967.
  • Akerlund B, Jarstrand C, Lindeke B et al. Effect of N acetylcysteine (NAC) treatment on HIV-1 infection: a double-blind placebo-controlled trial. Eur J Clin Pharmacol 1996; 50: 457–461.
  • Morris K. Glutathione may have a major role in HIV-1 disease. Lancet 1997; 349: 781.

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