Inhibition of neutral sphingomyelinase decreases elevated levels of nitrative and oxidative stress markers in liver ischemia–reperfusion injury

References

• Dogan S, Aslan M. Hepatic ischemia-reperfusion injury and therapeutic strategies to alleviate cellular damage. Hepatol Res 2011;41:103–17. doi: 10.1111/j.1872-034X.2010.00765.x
   PubMed Web of Science ®Google Scholar
• Jaeschke H, Bautista AP, Spolarics Z, Spitzer JJ. Superoxide generation by neutrophils and Kupffer cells during in vivo reperfusion after hepatic ischemia in rats. J Leukoc Biol 1992;52:377–82.
   PubMed Web of Science ®Google Scholar
• Tsukamoto H. Redox regulation of cytokine expression in Kupffer cells. Antioxid Redox Signal 2002;4:741–48. doi: 10.1089/152308602760598882
   PubMed Web of Science ®Google Scholar
• Colletti LM, Kunkel SL, Walz A, Burdick MD, Kunkel RG, Wilke CA, et al. The role of cytokine networks in the local liver injury following hepatic ischemia/reperfusion in the rat. Hepatology 1996;23:506–14. doi: 10.1002/hep.510230315
   PubMed Web of Science ®Google Scholar
• Urakami H, Abe Y, Grisham MB. Role of reactive metabolites of oxygen and nitrogen in partial liver transplantation: lessons learned from reduced-size liver ischaemia and reperfusion injury. Clin Exp Pharmacol Physiol 2007;34:912–19. doi: 10.1111/j.1440-1681.2007.04640.x
   PubMed Web of Science ®Google Scholar
• Isobe M, Katsuramaki T, Kimura H, Nagayama M, Matsuno T, Yagihashi A, et al. Role of inducible nitric oxide synthase on hepatic ischemia and reperfusion injury. Transplant Proc 2000;32:1650–52. doi: 10.1016/S0041-1345(00)01435-4
   PubMed Web of Science ®Google Scholar
• Lee VG, Johnson ML, Baust J, Laubach VE, Watkins SC, Billiar TR. The roles of iNOS in liver ischemia-reperfusion injury. Shock 2001;16:355–60. doi: 10.1097/00024382-200116050-00006
   PubMed Web of Science ®Google Scholar
• Novgorodov SA, Gudz TI. Ceramide and mitochondria in ischemia/reperfusion. J Cardiovasc Pharmacol 2009;53:198–208. doi: 10.1097/FJC.0b013e31819b52d5
   PubMed Web of Science ®Google Scholar
• Llacuna L, Marí M, Garcia-Ruiz C, Fernandez-Checa JC, Morales A. Critical role of acidic sphingomyelinase in murine hepatic ischemia-reperfusion injury. Hepatology 2006;44:561–752. doi: 10.1002/hep.21285
   PubMed Web of Science ®Google Scholar
• Wu BX, Clarke CJ, Hannun YA. Mammalian neutral sphingomyelinases: regulation and roles in cell signaling responses. Neuromol Med 2010;12:320–30. doi: 10.1007/s12017-010-8120-z
   PubMed Web of Science ®Google Scholar
• Sawai H, Hannun YA. Ceramide and sphingomyelinases in the regulation of stress responses. Chem Phys Lipids 1999;102:141–47. doi: 10.1016/S0009-3084(99)00082-1
   PubMed Web of Science ®Google Scholar
• Perrotta C, Clementi E. Biological roles of acid and neutral sphingomyelinases and their regulation by nitric oxide. Physiology (Bethesda) 2010;25:64–71. doi: 10.1152/physiol.00048.2009
   PubMed Web of Science ®Google Scholar
• Kone BC, Kuncewicz T, Zhang W, Yu ZY. Protein interactions with nitric oxide synthases: controlling the right time, the right place, and the right amount of nitric oxide. Am J Physiol Renal Physiol 2003;285:F178–F190. doi: 10.1152/ajprenal.00048.2003
   PubMedGoogle Scholar
• Zhang W, Kuncewicz T, Yu ZY, Zou L, Xu X, Kone BC. Protein-protein interactions involving inducible nitric oxide synthase. Acta Physiol Scand 2003;179:137–42. doi: 10.1046/j.1365-201X.2003.01119.x
   PubMedGoogle Scholar
• Won JS, Im YB, Khan M, Singh AK, Singh I. The role of neutral sphingomyelinase produced ceramide in lipopolysaccharide-mediated expression of inducible nitric oxide synthase. J Neurochem 2004;88:583–93. doi: 10.1046/j.1471-4159.2003.02165.x
   PubMed Web of Science ®Google Scholar
• Aslan M, Özcan F, Tuzcu H, Kıraç E, Elpek GO. Inhibition of neutral sphingomyelinase decreases arachidonic acid mediated inflammation in liver ischemia-reperfusion injury. Int J Clin Exp Pathol 2014;7:7814–23.
   PubMed Web of Science ®Google Scholar
• Tabatadze N, Savonenko A, Song H, Bandaru VV, Chu M, Haughey NJ. Inhibition of neutral sphingomyelinase-2 perturbs brain sphingolipid balance and spatial memory in mice. J Neurosci Res 2010;88:2940–51.
   PubMed Web of Science ®Google Scholar
• Dogan S, Ozlem Elpek G, Kirimlioglu Konuk E, Demir N, Aslan M. Measurement of intracellular biomolecular oxidation in liver ischemia-reperfusion injury via immuno-spin trapping. Free Radic Biol Med 2012;53:406–14. doi: 10.1016/j.freeradbiomed.2012.05.028
   PubMed Web of Science ®Google Scholar
• Curek GD, Cort A, Yucel G, Demir N, Ozturk S, Elpek GO, et al. Effect of astaxanthin on hepatocellular injury following ischemia/reperfusion. Toxicology 2010;267:147–53. doi: 10.1016/j.tox.2009.11.003
   PubMed Web of Science ®Google Scholar
• Beckman JS, Parks DA, Pearson JD, Marshall PA, Freeman BA. A sensitive fluorometric assay for measuring xanthine dehydrogenase and oxidase in tissues. Free Radic Biol Med 1989;6:607–15. doi: 10.1016/0891-5849(89)90068-3
   PubMed Web of Science ®Google Scholar
• Yücel I, Akar Y, Yücel G, Ciftçioğlu MA, Keleş N, Aslan M. Effect of hypercholesterolemia on inducible nitric oxide synthase expression in a rat model of elevated intraocular pressure. Vision Res 2005;45:1107–14. doi: 10.1016/j.visres.2004.11.018
   PubMed Web of Science ®Google Scholar
• Yoo HH, Son J, Kim DH. Liquid chromatography-tandem mass spectrometric determination of ceramides and related lipid species in cellular extracts. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;843:327–33. doi: 10.1016/j.jchromb.2006.06.025
   PubMed Web of Science ®Google Scholar
• Bui HH, Leohr JK, Kuo MS. Analysis of sphingolipids in extracted human plasma using liquid chromatography electrospray ionization tandem mass spectrometry. Anal Biochem. 2012;423:187–94. doi: 10.1016/j.ab.2012.01.027
   PubMed Web of Science ®Google Scholar
• Marí M, Fernández-Checa JC. Sphingolipid signalling and liver diseases. Liver Int 2007;27:440–50. doi: 10.1111/j.1478-3231.2007.01475.x
   PubMed Web of Science ®Google Scholar
• Luberto C, Hassler DF, Signorelli P, Okamoto Y, Sawai H, Boros E, et al. Inhibition of tumor necrosis factor-induced cell death in MCF7 by a novel inhibitor of neutral sphingomyelinase. J Biol Chem. 2002;277:41128–39. doi: 10.1074/jbc.M206747200
   PubMed Web of Science ®Google Scholar
• Ozer J, Ratner M, Shaw M, Bailey W, Schomaker S. The current state of serum biomarkers of hepatotoxicity. Toxicology 2008;245:194–205. doi: 10.1016/j.tox.2007.11.021
   PubMed Web of Science ®Google Scholar
• Corda S, Laplace C, Vicaut E, Duranteau J. Rapid reactive oxygen species production by mitochondria in endothelial cells exposed to tumor necrosis factor-alpha is mediated by ceramide. Am J Respir Cell Mol Biol 2001;24:762–68. doi: 10.1165/ajrcmb.24.6.4228
   PubMed Web of Science ®Google Scholar
• Lecour S, Van der Merwe E, Opie LH, Sack MN. Ceramide attenuates hypoxic cell death via reactive oxygen species signaling. J Cardiovasc Pharmacol 2006;47:158–63. doi: 10.1097/01.fjc.0000198520.28674.41
   PubMed Web of Science ®Google Scholar
• Enroth C, Eger BT, Okamoto K, Nishino T, Nishino T, Pai EF. Crystal structures of bovine milk xanthine dehydrogenase and xanthine oxidase: structure-based mechanism of conversion. Proc Natl Acad Sci USA 2000;97:10723–28. doi: 10.1073/pnas.97.20.10723
   PubMed Web of Science ®Google Scholar
• McKelvey TG, Höllwarth ME, Granger DN, Engerson TD, Landler U, Jones HP. Mechanisms of conversion of xanthine dehydrogenase to xanthine oxidase in ischemic rat liver and kidney. Am J Physiol 1988;254:G753–G760.
   PubMed Web of Science ®Google Scholar
• Pahan K, Sheikh FG, Khan M, Namboodiri AM, Singh I. Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. J Biol Chem 1998;273:2591–600. doi: 10.1074/jbc.273.5.2591
   PubMed Web of Science ®Google Scholar
• Katsuyama K, Shichiri M, Marumo F, Hirata Y. Role of nuclear factor-kappaB activation in cytokine- and sphingomyelinase-stimulated inducible nitric oxide synthase gene expression in vascular smooth muscle cells. Endocrinology 1998;139:4506–12. doi: 10.1210/endo.139.11.6309
   PubMed Web of Science ®Google Scholar
• Yang MS, Jou I, Inn-Oc H, Joe E. Sphingomyelinase but not ceramide induces nitric oxide synthase expression in rat brain microglia. Neurosci Lett 2001;311:133–36. doi: 10.1016/S0304-3940(01)02162-0
   PubMed Web of Science ®Google Scholar
• Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990;87:1620–24. doi: 10.1073/pnas.87.4.1620
   PubMed Web of Science ®Google Scholar
• Eiserich JP, Hristova M, Cross CE, Jones AD, Freeman BA, Halliwell B, et al. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature 1998;391:393–97. doi: 10.1038/34923
   PubMed Web of Science ®Google Scholar
• Aslan M, Yucel I, Ciftcioglu A, Savaş B, Akar Y, Yucel G, et al. Corneal protein nitration in experimental uveitis. Exp Biol Med (Maywood) 2007;232:1308–13. doi: 10.3181/0702-RM-34
   PubMed Web of Science ®Google Scholar
• Aslan M, Basaranlar G, Unal M, Ciftcioglu A, Derin N, Mutus B. Inhibition of neutral sphingomyelinase decreases elevated levels of inducible nitric oxide synthase and apoptotic cell death in ocular hypertensive rats. Toxicol Appl Pharmacol 2014;280:389–98. doi: 10.1016/j.taap.2014.08.026
   PubMed Web of Science ®Google Scholar
• Bhunia AK, Han H, Snowden A, Chatterjee S. Redox-regulated signaling by lactosylceramide in the proliferation of human aortic smooth muscle cells. J Biol Chem 1997;272:15642–49. doi: 10.1074/jbc.272.25.15642
   PubMed Web of Science ®Google Scholar
• Zhang Y, Li X, Carpinteiro A, Gulbins E. Acid sphingomyelinase amplifies redox signaling in pseudomonas aeruginosa-induced macrophage apoptosis. J Immunol 2008;181:4247–54. doi: 10.4049/jimmunol.181.6.4247
   PubMed Web of Science ®Google Scholar
• Stadtman ER, Oliver CN. Metal-catalyzed oxidation of proteins. Physiological consequences. J Biol Chem 1991;266:2005–08.
   PubMed Web of Science ®Google Scholar
• Tuma DJ, Thiele GM, Xu D, Klassen LW, Sorrell MF. Acetaldehyde and malondialdehyde react together to generate distinct protein adducts in the liver during long-term ethanol administration. Hepatology 1996;23:872–80. doi: 10.1002/hep.510230431
   PubMed Web of Science ®Google Scholar
• Shacter E. Protein oxidative damage. Methods Enzymol 2000;319:428–36. doi: 10.1016/S0076-6879(00)19040-8
   PubMed Web of Science ®Google Scholar
• Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 1994;233:357–63. doi: 10.1016/S0076-6879(94)33041-7
   PubMed Web of Science ®Google Scholar