Phytochemical treatments target kynurenine pathway induced oxidative stress

References

• World Health Organization. What are neurological disorders? 2016. Available from: http://www.who.int/features/qa/55/en
   Google Scholar
• Lee JM, Tan V, Lovejoy D, et al. Involvement of quinolinic acid in the neuropathogenesis of amyotrophic lateral sclerosis. Neuropharmacology. 2017;112:346–364. doi: 10.1016/j.neuropharm.2016.05.011
   PubMed Web of Science ®Google Scholar
• Lovelace MD, Varney B, Sundaram G, et al. Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases. Neuropharmacology. 2017;112:373–388. doi: 10.1016/j.neuropharm.2016.03.024
   PubMed Web of Science ®Google Scholar
• Bhangale JO, Acharya SR. Anti-Parkinson activity of petroleum ether extract of Ficus religiosa (L.) leaves. Adv Pharmacol Sci. 2016. DOI:10.1155/2016/9436106.
   PubMed Web of Science ®Google Scholar
• Essa MM, Vijayan RK, Castellano-Gonzalez G, et al. Neuroprotective effect of natural products against Alzheimer’s disease. Neurochem Res. 2012;37:1829–1842. doi: 10.1007/s11064-012-0799-9
   PubMed Web of Science ®Google Scholar
• Guillemin GJ, Brew BJ. Implications of the kynurenine pathway and quinolinic acid in Alzheimer’s disease. Redox Rep. 2002;7:199–206. doi: 10.1179/135100002125000550
   PubMed Web of Science ®Google Scholar
• Guillemin GJ, Kerr SJ, Brew BJ. Involvement of quinolinic acid in AIDS dementia complex. Neurotox Res. 2005;7:103–123. doi: 10.1007/BF03033781
   PubMed Web of Science ®Google Scholar
• Schwarcz R, Stone TW. The kynurenine pathway and the brain: challenges, controversies and promises. Neuropharmacology. 2017;112:237–247. doi: 10.1016/j.neuropharm.2016.08.003
   PubMed Web of Science ®Google Scholar
• Erhardt S, Schwieler L, Imbeault S, et al. The kynurenine pathway in schizophrenia and bipolar disorder. Neuropharmacology. 2017;112:297–306. doi: 10.1016/j.neuropharm.2016.05.020
   PubMed Web of Science ®Google Scholar
• Santamaría-del Ángel D, Labra-Ruíz NA, García-Cruz ME, et al. Comparative effects of catechin, epicatechin and N-Ω-nitroarginine on quinolinic acid-induced oxidative stress in rat striatum slices. Biomed Pharmacother. 2016;78:210–215. doi: 10.1016/j.biopha.2016.01.016
   PubMed Web of Science ®Google Scholar
• Stylos E, Chatziathanasiadou MV, Syriopoulou A, et al. Liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) based bioavailability determination of the major classes of phytochemicals. J Chromatogr B. 2016. DOI:10.1016/j.jchromb.2016.12.022.
   PubMed Web of Science ®Google Scholar
• Ayyappan P, Palayyan SR, Kozhiparambil Gopalan R. Attenuation of oxidative damage by Boerhaavia diffusa L. against different neurotoxic agents in rat brain homogenate. J Diet Suppl. 2016;13:300–312. doi: 10.3109/19390211.2015.1036186
   PubMedGoogle Scholar
• Heyes MP, Saito K, Crowley JS, et al. Quinolinic acid and kynurenine pathway metabolism in inflammatory and non-inflammatory neurological disease. Brain. 1992;115:1249–1273. doi: 10.1093/brain/115.5.1249
   PubMed Web of Science ®Google Scholar
• Savitz J, Drevets WC, Wurfel BE, et al. Reduction of kynurenic acid to quinolinic acid ratio in both the depressed and remitted phases of major depressive disorder. Brain Behav Immun. 2015;46:55–59. doi: 10.1016/j.bbi.2015.02.007
   PubMed Web of Science ®Google Scholar
• Clark SM, Pocivavsek A, Nicholson JD, et al. Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals. J Psychiatry Neurosci. 2016;41:386–394. doi: 10.1503/jpn.150226
   PubMed Web of Science ®Google Scholar
• Boeck CR, Ganzella M, Lottermann A, et al. NMDA preconditioning protects against seizures and hippocampal neurotoxicity induced by quinolinic acid in mice. Epilepsia. 2004;45:745–750. doi: 10.1111/j.0013-9580.2004.65203.x
   PubMed Web of Science ®Google Scholar
• Schwarcz R, Whetsell WO, Mangano RM. Quinolinic acid: an endogenous metabolite that produces axon-sparing lesions in rat brain. Science. 1983;219:316–318. doi: 10.1126/science.6849138
   PubMed Web of Science ®Google Scholar
• Cho HJ, Savitz J, Dantzer R. Sleep disturbance and kynurenine metabolism in a group of currently depressed, previously depressed, and never depressed subjects. Brain Behav Immun. 2016;57:e14. doi: 10.1016/j.bbi.2016.07.049
   Google Scholar
• Bryleva EY, Brundin L. Kynurenine pathway metabolites and suicidality. Neuropharmacology. 2017;112:324–330. doi: 10.1016/j.neuropharm.2016.01.034
   PubMed Web of Science ®Google Scholar
• Coccaro EF, Lee R, Fanning JR, et al. Tryptophan, kynurenine, and kynurenine metabolites: relationship to lifetime aggression and inflammatory markers in human subjects. Psychoneuroendocrinology. 2016;71:189–196. doi: 10.1016/j.psyneuen.2016.04.024
   PubMed Web of Science ®Google Scholar
• Moroni F. Tryptophan metabolism and brain function: focus on kynurenine and other indole metabolites. Eur J Pharmacol. 1999;375:87–100. doi: 10.1016/S0014-2999(99)00196-X
   PubMed Web of Science ®Google Scholar
• Zhuravlev AV, Zakharov GA, Shchegolev BF, et al. Antioxidant properties of kynurenines: density functional theory calculations. PLoS Comput Biol. 2017;12(11):e1005213. doi: 10.1371/journal.pcbi.1005213
   Web of Science ®Google Scholar
• Perkins MN, Stone TW. An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res. 1982;247:184–187. doi: 10.1016/0006-8993(82)91048-4
   PubMed Web of Science ®Google Scholar
• Neméth H, Toldi J, Vecséi L. Kynurenines, Parkinson’s disease and other neurodegenerative disorders: preclinical and clinical studies. J Neural Transm. 2006;70:285–304.
   Google Scholar
• Jhamandas KH, Boegman RJ, Beninger RJ, et al. Excitotoxicity of quinolinic acid: modulation by endogenous antagonists. Neurotox Res. 2000;2:139–155. doi: 10.1007/BF03033790
   PubMedGoogle Scholar
• Achour I, Arel-Dubeau AM, Renaud J, et al. Oleuropein prevents neuronal death, mitigates mitochondrial superoxide production and modulates autophagy in a dopaminergic cellular model. Int J Mol Sci. 2016;17:1293–1217. doi: 10.3390/ijms17081293
   Web of Science ®Google Scholar
• Kim MS, Bang JH, Lee J, et al. Fructus mume ethanol extract prevents inflammation and normalizes the septohippocampal cholinergic system in a rat model of chronic cerebral hypoperfusion. J Med Food. 2016;19:196–204. doi: 10.1089/jmf.2015.3512
   PubMed Web of Science ®Google Scholar
• Prasad SN, Bharath MMS, Muralidhara. Neurorestorative effects of eugenol, a spice bioactive: evidence in cell model and its efficacy as an intervention molecule to abrogate brain oxidative dysfunctions in the streptozotocin diabetic rat. Neurochem Int. 2016;95:24–36. doi: 10.1016/j.neuint.2015.10.012
   PubMed Web of Science ®Google Scholar
• Dhadde SB, Nagakannan P, Roopesh M, et al. Effect of embelin against 3-nitropropionic acid-induced Huntington’s disease in rats. Biomed Pharmacother. 2016;77:52–58. doi: 10.1016/j.biopha.2015.11.009
   PubMed Web of Science ®Google Scholar
• Jang M, Cho IH. Sulforaphane ameliorates 3-nitropropionic acid-induced striatal toxicity by activating the Keap1-Nrf2-ARE pathway and inhibiting the MAPKs and NF-κB pathways. Mol Neurobiol. 2016;53:2619–2635. doi: 10.1007/s12035-015-9230-2
   PubMed Web of Science ®Google Scholar
• Koshiguchi M, Komazaki H, Hirai S, et al. Ferulic acid suppresses expression of tryptophan metabolic key enzyme indoleamine 2, 3-dioxygenase via NFκB and p38 MAPK in lipopolysaccharide-stimulated microglial cells. Biosci Biotechnol Biochem. 2017;8451:1–6.
   Google Scholar
• Colle D, Santos DB, Hartwig JM, et al. Succinobucol, a lipid-lowering drug, protects against 3-nitropropionic acid-induced mitochondrial dysfunction and oxidative stress in SH-SY5Y cells via upregulation of glutathione levels and glutamate cysteine ligase activity. Mol Neurobiol. 2016;53:1280–1295. doi: 10.1007/s12035-014-9086-x
   PubMed Web of Science ®Google Scholar
• Adefegha SA, Oboh G, Molehin OR, et al. Chromatographic fingerprint analysis, acetylcholinesterase inhibitory properties and antioxidant activities of redflower ragleaf (Crassocephalum crepidioides) extract. J Food Biochem. 2015. DOI:10.1111/jfbc.12200.
   PubMed Web of Science ®Google Scholar
• Marques NF, Stefanello ST, Froeder ALF, et al. Centella asiatica and its fractions reduces lipid peroxidation induced by quinolinic acid and sodium nitroprusside in rat brain regions. Neurochem Res. 2015;40:1197–1210. doi: 10.1007/s11064-015-1582-5
   PubMed Web of Science ®Google Scholar
• Oboh G, Ogunruku OO, Oyeleye SI, et al. Phenolic extracts from Clerodendrum volubile leaves inhibit cholinergic and monoaminergic enzymes relevant to the management of some neurodegenerative diseases. J Diet Suppl. 2017;14:358–371. doi: 10.1080/19390211.2016.1237401
   PubMedGoogle Scholar
• Singh S. Neuroprotective activity of curcumin in combination with piperine against quinolinic acid–induced neurodegeneration in rats. Alzheimer’s Dement. 2016;12:P621. doi: 10.1016/j.jalz.2016.06.1238
   Google Scholar
• Morales-Martínez A, Sánchez-Mendoza A, Martínez-Lazcano JC, et al. Essential fatty acid-rich diets protect against striatal oxidative damage induced by quinolinic acid in rats. Nutr Neurosci. 2016. DOI:10.1080/1028415X.2016.1147683.
   PubMed Web of Science ®Google Scholar
• Schwarcz R, Bruno JP, Muchowski PJ, et al. Kynurenines in the mammalian brain: when physiology meets pathology. Nat Rev Neurosci. 2012;13(7):465–477. doi: 10.1038/nrn3257
   PubMed Web of Science ®Google Scholar