References
- Webber LS, Srinivasan SR, Wattigney WA, et al. Tracking of serum lipids and lipoproteins from childhood to adulthood, The Bogalusa heart study. Am J Epidemiol. 1991;133:884–899. https://www.ncbi.nlm.nih.gov/pubmed/2028978. doi: 10.1093/oxfordjournals.aje.a115968
- Yamamoto-Kimura L, Posadas-Romero C, Posadas-Sánchez R, et al. Prevalence and interrelations of cardiovascular risk factors in urban and rural Mexican adolescents. J Adolesc Health. 2006;38:591–598. DOI:10.1016/j.jadohealth.2005.04.004.
- Zheng W, Zhao A, Xue Y, et al. Gender and urban-rural difference in anthropometric indices predicting dislipidemia in Chinese primary schoolchildren: a cross-sectional study. Lipids Health Dis. 2016;15:87–94. DOI:10.1186/s12944-016-0255-y.
- Bianba B, Yangzong Y, Gonggalanzi G, et al. Anthropometric measures of 9- to 10-year-old native Tibetan children living at 3700 and 4300 m above sea level and han Chinese living at 3700m. Medicine (Baltimore). 2015;94:e1516. DOI:10.1097/MD.0000000000001516.
- Rimoldi S, Rexhaj E, Duplain H, et al. Acute and chronic altitude-induced cognitive dysfunction in children and adolescents. J Pediatr. 2016;169:238–243. DOI:10.1016/j.jpeds.2015.10.009.
- Wu A, Budge P, Williams J, et al. Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru. PLoS One. 2015;10:e0130233. DOI:10.1371/journal.pone.0130233.
- Hirschler V, Maccallini G, Aranda C, et al. Dyslipidemia without obesity in indigenous Argentinean children living at high altitude. J Pediatr. 2012;161:646–651. DOI:10.1016/j.jpeds.2012.04.008.
- Mohanna S, Baracco R, Seclén S. Lipid profile, waist circumference, and body mass index in a high altitude population. High Alt Med Biol. 2006;7:245–255. DOI:10.1089/ham.2006.7.245.
- Santos JL, Pérez-Bravo F, Carrasco E, et al. Low prevalence of type 2 diabetes despite a high average body mass index in the Aymara natives from Chile. Nutrition. 2001;17:305–309. https://www.ncbi.nlm.nih.gov/pubmed/11369169. doi: 10.1016/S0899-9007(00)00551-7
- Beall CM. High-altitude adaptations. Lancet. 2003;362:14–15. https://www.ncbi.nlm.nih.gov/pubmed/14698112. doi: 10.1016/S0140-6736(03)15058-1
- Bailey DM, Davies B, Young I, et al. A potential role for free radical-mediated skeletal muscle soreness in the pathophysiology of acute mountain sickness. Aviat Space Environ Med. 2001;72:513–521. https://www.ncbi.nlm.nih.gov/pubmed/11396556.
- Askew EW. Work at high altitude and oxidative stress: antioxidant nutrients. Toxicology. 2002;180:107–119. https://www.ncbi.nlm.nih.gov/pubmed/12324188. doi: 10.1016/S0300-483X(02)00385-2
- Parthasarathy S, Barnett J, Fong LG. High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein. Biochem Biophys Acta. 1990;1044:275–283. https://www.ncbi.nlm.nih.gov/pubmed/2344447. doi: 10.1016/0005-2760(90)90314-N
- Mackness MI, Arrol S, Abbott CA, et al. Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase. Atherosclerosis. 1993;104:129–135. https://www.ncbi.nlm.nih.gov/pubmed/8141836. doi: 10.1016/0021-9150(93)90183-U
- Nevin DN, Zambon A, Furlong CE. Paraoxonase genotypes, lipoprotein lipase activity, and HDL. Arterioscler Thromb Vasc Biol. 1996;16:1243–1249. https://www.ncbi.nlm.nih.gov/pubmed/8857920. doi: 10.1161/01.ATV.16.10.1243
- Censo. 2010. [accessed 2015-03-09] http://www.censo2010.indec.gov.ar.
- Brites FD, Verona J, Schreier LE, et al. Paraoxonase1 and platelet-activating factor acetyl hydrolase activities in patients with low HDL-cholesterol levels with or without primary hypertriglyceridemia. Arch Med Res. 2004;35:235–240. DOI:10.1016/j.arcmed.2004.02.002.
- Mackness B, Durrington P, Mcelduff P, et al. Low paraoxonase activity predicts coronary events in the caerphilly prospective study. Circulation. 2003;107:2775–2779. DOI:10.1161/01.CIR.0000070954.00271.13.
- Mackness MI, Mackness B, Durrington PN, et al. Paraoxonase: biochemistry, genetics and relationship to plasma lipoproteins. Curr Opin Lipidol. 1996;7:69–76. https://www.ncbi.nlm.nih.gov/pubmed/8743898. doi: 10.1097/00041433-199604000-00004
- Sherpa LY, Deji, Stigum H, Chongsuvivatwong V, et al. Obesity in Tibetans aged 30-70 living at different altitudes under the north and south faces of Mt. Everest. Int J Environ Res Public Health. 2010;7:1670–1680. DOI:10.3390/ijerph7041670.
- Sierra-Johnson J, Romero-Corral A, Somers VK, et al. Effect of altitude on leptin levels, does it go up or down? J Appl Physiol. 2008;105:1684–1685. DOI:10.1152/japplphysiol.01284.2007.
- Millán J, Pintó X, Muñoz A, et al. Lipoprotein ratios: physiological significance and clinical usefulness in cardiovascular prevention. Vasc Health Risk Manag. 2009;5:757–765. https://www.ncbi.nlm.nih.gov/pubmed/19774217.
- McLaughlin T, Abbasi F, Cheal K, et al. Use of metabolic markers to identify overweight individuals who are insulin resistant. Ann Intern Med. 2003;139:802–809. https://www.ncbi.nlm.nih.gov/pubmed/14623617. doi: 10.7326/0003-4819-139-10-200311180-00007
- Hanak V, Munoz J, Teague J, et al. Accuracy of the triglyceride to high-density lipoprotein cholesterol ratio for prediction of the low-density lipoprotein phenotype B. Am J Cardiol. 2004;94:219–222. DOI:10.1016/j.amjcard.2004.03.069.
- Wägner AM, Jorba O, Rigla M, et al. LDL-cholesterol/apolipoprotein B ratio is a good predictor of LDL phenotype B in type 2 diabetes. Acta Diabetol. 2002;39:215–220. DOI:10.1007/s005920200037.
- Jefferson J, Simoni J, Escudero E, et al. Increased oxidative stress following acute and chronic high altitude. High Alt Med Biol. 2004;5:61–69. DOI:10.1089/152702904322963690.
- Agostoni A, Gerli GC, Beretta L, et al. Erythrocyte antioxidant enzymes and selenium serum levels in an Andean population. Clin Chim Acta. 1983;133:153–157. https://www.ncbi.nlm.nih.gov/pubmed/6627681. doi: 10.1016/0009-8981(83)90400-X
- Lüneburg N, Siques P, Brito J, et al. Long-term chronic intermittent hypobaric hypoxia in rats causes an imbalance in the asymmetric dimethylarginine/nitric oxide pathway and ROS activity: a possible synergistic mechanism for altitude pulmonary hypertension? Pulm Med. 2016;2016:6578578. DOI:10.1155/2016/6578578.
- Chao WH, Askew EW, Roberts DE, et al. Oxidative stress in humans during work at moderate altitude. J Nutr. 1999;129:2009–2012. https://www.ncbi.nlm.nih.gov/pubmed/10539777. doi: 10.1093/jn/129.11.2009
- Radák Z, Lee K, Choi W, et al. Oxidative stress induced by intermittent exposure at a simulated altitude of 4000 m decreases mitochondrial superoxide dismutase content in soleus muscle of rats. Eur J Appl Physiol Occup Physiol. 1994;69:392–395. https://www.ncbi.nlm.nih.gov/pubmed/7875134. doi: 10.1007/BF00865401
- Vats P1, Singh VK, Singh SN, et al. Glutathione metabolism under high-altitude stress and effect of antioxidant supplementation. Aviat Space Environ Med. 2008;79:1106–1111. https://www.ncbi.nlm.nih.gov/pubmed/19070306. doi: 10.3357/ASEM.2305.2008
- Møller P, Loft S, Lundby C, et al. Acute hypoxia and hypoxic exercise induce DNA strand breaks and oxidative DNA damage in humans. FASEB J. 2001;15:1181–1186. https://www.ncbi.nlm.nih.gov/pubmed/11344086. doi: 10.1096/fj.00-0703com
- Aviram M, Rosenblat M, Billecke S, et al. Human serum paraoxonase (PON1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants. Free Radic Biol Med. 1999;26:892–904. https://www.ncbi.nlm.nih.gov/pubmed/10232833. doi: 10.1016/S0891-5849(98)00272-X
- Sentí M, Tomás M, Fitó M, et al. Antioxidant paraoxonase activity in the metabolic syndrome. J Clin Endocrinol Metab. 2003;88:5422–5426. DOI:10.1210/jc.2003-030648.
- Yang Y, Ma L, Guan W, et al. Differential plasma proteome analysis in patients with high-altitude pulmonary edema at the acute and recovery phases. Exp Ther Med. 2014;7:1160–1166. DOI:10.3892/etm.2014.1548.
- Ahmad Y, Sharma NK, Ahmad MF, et al. Proteomic identification of novel differentiation plasma protein markers in hypobaric hypoxia-induced rat model. PLoS One. 2014;9:e98027. DOI:10.1371/journal.pone.0098027.
- Browne RW, Shelly WB, Bloom MS, et al. Distribution of high-density lipoprotein particle components in human follicular fluid and sera and their associations with embryo morphology parameters during IVF. Hum Reprod. 2008;23:1884–1894. DOI:10.1093/humrep/den183.
- Korytowski W, Wawak K, Pabisz P, et al. Impairment of macrophage cholesterol efflux by cholesterol hydroperoxide trafficking: implications for atherogenesis under oxidative stress. Arterioscler Thromb Vasc Biol. 2015;35:2104–2113. DOI:10.1161/ATVBAHA.115.306210.