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Redox Report
Communications in Free Radical Research
Volume 24, 2019 - Issue 1
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Research Articles

Resveratrol improves osteogenic differentiation of senescent bone mesenchymal stem cells through inhibiting endogenous reactive oxygen species production via AMPK activation

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References

  • Yang SQ, Duan XH. Epigenetics, bone remodeling and osteoporosis. Curr Stem Cell Res T. 2018;13:101–109.
  • Hsu WL, Chen CY, Tsauo JY, et al. Balance control in elderly people with osteoporosis. J Formos Med Assoc. 2014;113:334–339. doi: 10.1016/j.jfma.2014.02.006
  • Li Y, Wu Q, Wang YJ, et al. Senescence of mesenchymal stem cells. Int J Mol Med. 2017;39:775–782. doi: 10.3892/ijmm.2017.2912
  • Li C, Wei GJ, Gu Q, et al. Donor age and cell passage affect osteogenic ability of rat bone marrow mesenchymal stem cells. Cell Biochem Biophys. 2015;72:543–549. doi: 10.1007/s12013-014-0500-9
  • Singh L, Brennan TA, Russell E, et al. Aging alters bone-fat reciprocity by shifting in vivo mesenchymal precursor cell fate towards an adipogenic lineage. Bone. 2016;85:29–36. doi: 10.1016/j.bone.2016.01.014
  • Murphy MP. How mitochondria produce reactive oxygen species. Biochem J. 2009;417:1–13. doi: 10.1042/BJ20081386
  • Ludin A, Gur-Cohen S, Golan K, et al. Reactive oxygen species regulate hematopoietic stem cell self-renewal, migration and development, as well as their bone marrow microenvironment. Antioxid Redox Signal. 2014;21:1605–1619. doi: 10.1089/ars.2014.5941
  • Tan DQ, Suda T. Reactive oxygen species and mitochondrial homeostasis as regulators of stem cell fate and function. Antioxid Redox Signal. 2018;29:149–168. doi: 10.1089/ars.2017.7273
  • Jeong SG, Cho GW. Endogenous ROS levels are increased in replicative senescence in human bone marrow mesenchymal stromal cells. Biochem Bioph Res Co. 2015;460:971–976. doi: 10.1016/j.bbrc.2015.03.136
  • Wauquier F, Leotoing L, Coxam V, et al. Oxidative stress in bone remodelling and disease. Trends Mol Med. 2009;15:468–477. doi: 10.1016/j.molmed.2009.08.004
  • Atashi F, Modarressi A, Pepper MS. The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review. Stem Cells Dev. 2015;24:1150–1163. doi: 10.1089/scd.2014.0484
  • Zhao Y, Hu XB, Liu YJ, et al. ROS signaling under metabolic stress: cross-talk between AMPK and AKT pathway. Mol Cancer. 2017;16:79. doi: 10.1186/s12943-017-0648-1
  • Zhang DY, Pan Y, Zhang C, et al. Wnt/beta-catenin signaling induces the aging of mesenchymal stem cells through promoting the ROS production. Mol Cell Biochem. 2013;374:13–20. doi: 10.1007/s11010-012-1498-1
  • Chen HQ, Liu XB, Chen H, et al. Role of SIRT1 and AMPK in mesenchymal stem cells differentiation. Ageing Res Rev. 2014;13:55–64. doi: 10.1016/j.arr.2013.12.002
  • Hwang AB, Ryu EA, Artan M, et al. Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans. Proc Natl Acad Sci USA. 2014;111:E4458–E4467. doi: 10.1073/pnas.1411199111
  • Fan XX, Leung EL, Xie Y, et al. Suppression of lipogenesis via reactive oxygen species-AMPK signaling for treating malignant and proliferative diseases. Antioxid Redox Signal. 2018;28:339–357. doi: 10.1089/ars.2017.7090
  • Tseng PC, Hou SM, Chen RJ, et al. Resveratrol promotes osteogenesis of human mesenchymal stem cells by upregulating RUNX2 gene expression via the SIRT1/FOXO3A axis. J Bone Miner Res. 2011;26:2552–2563. doi: 10.1002/jbmr.460
  • Ornstrup MJ, Harslof T, Kjaer TN, et al. Resveratrol increases bone mineral density and bone alkaline phosphatase in obese men: a randomized placebo-controlled trial. J Clin Endocr Metab. 2014;99:4720–4729. doi: 10.1210/jc.2014-2799
  • Mobasheri A, Shakibaei M. Osteogenic effects of resveratrol in vitro: potential for the prevention and treatment of osteoporosis. Ann NY Acad Sci. 2013;1290:59–66. doi: 10.1111/nyas.12145
  • Lan F, Weikel KA, Cacicedo JM, et al. Resveratrol-induced AMP-activated protein kinase activation is cell-type dependent: lessons from basic research for clinical application. Nutrients. 2017;9:751. doi: 10.3390/nu9070751
  • Lin CH, Li NT, Cheng HS, et al. Oxidative stress induces imbalance of adipogenic/osteoblastic lineage commitment in mesenchymal stem cells through decreasing SIRT1 functions. J Cell Mol Med. 2018;22:786–796.
  • Yang SR, Park JR, Kang KS. Reactive oxygen species in mesenchymal stem cell aging: implication to lung diseases. Oxid Med Cell Longev. 2015;2015:486263.
  • Chandrasekaran A, Idelchik MDS, Melendez JA. Redox control of senescence and age-related disease. Redox Biol. 2017;11:91–102. doi: 10.1016/j.redox.2016.11.005
  • Lagouge M, Argmann C, Gerhart-Hines Z, et al. Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1 alpha. Cell. 2006;127:1109–1122. doi: 10.1016/j.cell.2006.11.013
  • Li J, Yu S, Ying J, et al. Resveratrol prevents ROS-induced apoptosis in high glucose-treated retinal capillary endothelial cells via the activation of AMPK/sirt1/PGC-1alpha pathway. Oxid Med Cell Longev. 2017;2017:7584691.
  • Kim EK, Lim S, Park JM, et al. Human mesenchymal stem cell differentiation to the osteogenic or adipogenic lineage is regulated by AMP-activated protein kinase. J Cell Physiol. 2012;227:1680–1687. doi: 10.1002/jcp.22892
  • Eijkelenboom A, Burgering BMT. FOXOs: signalling integrators for homeostasis maintenance. Nat Rev Mol Cell Bio. 2013;14:83–97. doi: 10.1038/nrm3507
  • Greer EL, Oskoui PR, Banko MR, et al. The energy sensor AMP-activated protein kinase directly regulates the mammalian FOXO3 transcription factor. J Biol Chem. 2007;282:30107–30119. doi: 10.1074/jbc.M705325200
  • Klotz LO, Sanchez-Ramos C, Prieto-Arroyo I, et al. Redox regulation of FoxO transcription factors. Redox Biol. 2015;6:51–72. doi: 10.1016/j.redox.2015.06.019
  • Shimobayashi M, Hall MN. Making new contacts: the mTOR network in metabolism and signalling crosstalk. Nat Rev Mol Cell Bio. 2014;15:155–162. doi: 10.1038/nrm3757