131
Views
4
CrossRef citations to date
0
Altmetric
Original Articles

Dissociating medication effects from learning and practice effects in a neurocognitive study of schizophrenia: Olanzapine versus haloperidol

, , , , , , & show all
Pages 322-338 | Received 12 Apr 2006, Published online: 05 Jun 2007

References

  • Addington , D. , Addington , J. and Schissel , B. 1990 . A depression rating scale for schizophrenics . Schizophrenia Research , 3 : 247 – 251 .
  • Beasley , C. M. J. , Tollefson , G. , Tran , P. , Satterlee , W. , Sanger , T. and Hamilton , S. 1996 . Olanzapine versus placebo and haloperidol: Acute phase results of the North American double-blind olanzapine trial . Neuropsychopharmacology , 14 : 111 – 123 .
  • Beglinger , L. J. , Crawford-Miller , J. and Kareken , D. A. 2003 . Neuropsychological practice effects and change detection in people with schizophrenia . Schizophrenia Research , 62 : 191 – 194 .
  • Bédard , M. A. , Scherer , H. , Delorimier , J. , Stip , E. and Lalonde , P. 1996 . Differential effects of D2- and D4-blocking neuroleptics on the procedural learning of schizophrenic patients . Canadian Journal of Psychiatry—Revue Canadienne de Psychiatrie , 41 : S21 – S24 .
  • Bédard , M. A. , Scherer , H. , Stip , E. , Cohen , H. , Rodriguez , J. P. and Richer , F. 2000 . Procedural learning in schizophrenia: Further consideration on the deleterious effect of neuroleptics . Brain and Cognition , 43 : 31 – 39 .
  • Bilder , R. M. , Goldman , R. S. , Volavka , J. , Czobor , P. , Hoptman , M. Sheitman , B. 2002 . Neurocognitive effects of clozapine, olanzapine, risperidone, and haloperidol in patients with chronic schizophrenia or schizoaffective disorder . American Journal of Psychiatry , 159 : 1018 – 1028 .
  • Blyler , C. R. and Gold , J. M. 2000 . “ Cognitive effects of typical antipsychotic treatment: Another look ” . In Cognitive deficits in schizophrenia , Edited by: Sharma , T. and Harvey , P. D. 241 – 265 . Oxford, , UK : Oxford University Press .
  • Brickenkamp , R. and Zillmer , E. 1998 . The d2 test of attention , Seattle, WA : Hogrefe & Huber Publishers .
  • Cassens , G. , Inglis , A. K. , Appelbaum , P. S. and Gutheil , T. G. 1990 . Neuroleptics: Effects on neuropsychological function in chronic schizophrenic patients . Schizophrenia Bulletin , 16 : 477 – 499 .
  • Dikmen , S. S. , Heaton , R. K. , Grant , I. and Temkin , N. R. 1999 . Test–retest reliability and practice effects of Expanded Halsted-Reitan Neuropsychological Test Battery . Journal of the International Neuropsychological Society , 5 : 346 – 356 .
  • Golden , C. J. 1978 . Stroop Color and Word Test: Manual for clinical and experimental uses , Chicago : Stoelting Company .
  • Green , M. F. 1998 . Schizophrenia from a neurocognitive perspective: Probing the impenetrable darkness , Boston : Allyn & Bacon .
  • Green , M. F. , Kern , R. S. , Braff , D. L. and Mintz , J. 2000 . Neurocognitive deficits and functional outcome in schizophrenia: Are we measuring the “right stuff”? . Schizophrenia Bulletin , 26 ( 1 ) : 119 – 136 .
  • Green , M. F. , Marder , S. R. , Glynn , S. M. , McGurk , S. R. , Wirshing , W. C. Wirshing , D. A. 2002 . The neurocognitive effects of low-dose haloperidol: A two-year comparison with risperidone . Biological Psychiatry , 51 : 972 – 978 .
  • Gregory , R. J. 1987 . Adult intellectual assessment , Boston : Allyn & Bacon .
  • Harvey , P. D. and Keefe , R. S. 2001 . Studies of cognitive change in patients with schizophrenia following novel antipsychotic treatment . American Journal of Psychiatry , 158 : 176 – 184 .
  • Harvey , P. D. , Moriarty , P. J. , Serper , M. R. , Schnur , E. and Lieber , D. 2000 . Practice-related improvement in information processing with novel antipsychotic treatment . Schizophrenia Research , 46 : 139 – 148 .
  • Hill , S. K. , Schuepbach , D. , Herbener , E. S. , Keshavan , M. S. and Sweeney , J. A. 2004 . Pretreatment and longitudinal studies of neuropsychological deficits in antipsychotic-naive patients with schizophrenia . Schizophrenia Research , 68 : 49 – 63 .
  • Kapur , S. , Remington , G. , Jones , C. , Wilson , A. , DaSilva , J. Houle , S. 1996 . High levels of dopamine D2 receptor occupancy with low-dose haloperidol treatment: A PET study . American Journal of Psychiatry , 153 : 948 – 950 .
  • Kay , S. R. , Opler , L. A. and Fiszbein , A. 1986 . Positive and Negative Syndrome Scale (PANSS) for schizophrenia . Schizophrenia Bulletin , 13 : 261 – 276 .
  • Keefe , R. S. , Seidman , L. J. , Christensen , B. K. , Hamer , R. M. , Sharma , T. Sitskoorn , M. M. 2004 . Comparative effect of atypical and conventional antipsychotic drugs on neurocognition in first-episode psychosis: A randomized, double-blind trial of olanzapine versus low doses of haloperidol . American Journal of Psychiatry , 161 : 985 – 995 .
  • Kumari , V. , Corr , P. J. , Mulligan , O. F. , Cotter , P. A. , Checkley , S. A. and Gray , J. A. 1997 . Effects of acute administration of d-amphetamine and haloperidol on procedural learning in man . Psychopharmacology (Berlin) , 129 : 271 – 276 .
  • Kumari , V. , Gray , J. A. , Honey , G. D. , Soni , W. , Bullmore , E. T. Williams , S. C. 2002 . Procedural learning in schizophrenia: A functional magnetic resonance imaging investigation . Schizophrenia Research , 57 : 97 – 107 .
  • Lezak , M. 1995 . Neuropsychological assessment , 3rd ed. , New York : Oxford University Press .
  • Marder , S. R. and Fenton , W. 2004 . Measurement and treatment research to improve cognition in schizophrenia: NIMH MATRICS initiative to support the development of agents for improving cognition in schizophrenia . Schizophrenia Research , 72 : 5 – 9 .
  • McCaffrey , R. J. , Duff , K. and Westervelt , H. J. 2002 . Practitioner's guide to evaluating change with neuropsychological assessment instruments , New York : Kluwer Academic/Plenum .
  • Mega , M. S. and Cummings , J. L. 1994 . Frontal-subcortical circuits and neuropsychiatric disorders . Journal of Neuropsychiatry and Clinical Neurosciences , 6 : 358 – 370 .
  • Meltzer , H. Y. and McGurk , S. R. 1999 . The effects of clozapine, risperidone, and olanzapine on cognitive function in schizophrenia . Schizophrenia Bulletin , 25 : 233 – 255 .
  • Nordstrom , A. L. , Farde , L. , Wiesel , F. A. , Forslund , K. , Pauli , S. Halldin , C. 1993 . Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: A double-blind PET study of schizophrenic patients . Biological Psychiatry , 33 : 227 – 235 .
  • Oltmanns , T. F. 1978 . Selective attention in schizophrenic and manic psychoses: The effect of distraction in information processing . Journal of Abnormal Psychology , 87 : 212 – 225 .
  • Oltmanns , T. F. and Neale , J. M. 1975 . Schizophrenic performance when distractors are present: Attentional deficit or differential task difficulty . Journal of Abnormal Psychology , 84 : 205 – 209 .
  • Palermero-Neto , J. 1997 . Dopaminergic systems: Dopamine receptors . Psychiatric Clinics of North America , 20 : 705 – 721 .
  • Paquet , F. , Soucy , J. P. , Stip , E. , Levesque , M. , Elie , A. and Bedard , M. A. 2004 . Comparison between olanzapine and haloperidol on procedural learning and the relationship with striatal D2 receptor occupancy in schizophrenia . Journal of Neuropsychiatry and Clinical Neurosciences , 16 : 47 – 56 .
  • Peretti , C. S. , Danion , J. M. , Kauffmann-Muller , F. , Grange , D. , Patat , A. and Rosenzweig , P. 1997 . Effects of haloperidol and amisulpride on motor and cognitive skill learning in healthy volunteers . Psychopharmacology (Berlin) , 131 : 329 – 338 .
  • Purdon , S. E. , Jones , B. D. , Stip , E. , Labelle , A. , Addington , D. David , S. R. 2000 . Neuropsychological change in early phase schizophrenia during 12 months of treatment with olanzapine, risperidone, or haloperidol . Archives of General Psychiatry , 57 : 249 – 258 .
  • Purdon , S. E. , Malla , A. , Labelle , A. and Lit , W. 2001 . Neuropsychological change in patients with schizophrenia after treatment with quetiapine or haloperidol . Journal of Psychiatry and Neuroscience , 26 : 137 – 149 .
  • Purdon , S. E. , Woodward , N. , Lindborg , S. R. and Stip , E. 2003 . Procedural learning in schizophrenia after 6 months of double-blind treatment with olanzapine, risperidone, and haloperidol . Psychopharmacology (Berlin) , 169 : 390 – 397 .
  • Sax , K. W. , Strakowski , S. M. and Keck , P. E. Jr . 1998 . Attentional improvement following quetiapine fumarate treatment in schizophrenia . Schizophrenia Research , 33 : 151 – 155 .
  • Scherer , H. , Stip , E. , Paquet , F. and Bédard , M. A. 2003 . Mild procedural learning disturbances in neuroleptic-naive patients with schizophrenia . Journal of Neuropsychiatry and Clinical Neurosciences , 15 : 58 – 63 .
  • Serper , M. R. , Bergman , R. L. and Harvey , P. D. 1990 . Medication may be required for the development of automatic information processing in schizophrenia . Psychiatry Research , 32 : 281 – 288 .
  • Smith , R. C. I. 2001 . The effects of olanzapine on neurocognitive functioning in medication-refractory schizophrenia . International Journal of Neuropsychopharmacology , 4 : 239 – 250 .
  • Spohn , H. E. and Strauss , M. E. 1989 . Relation of neuroleptic and anticholinergic medication to cognitive functions in schizophrenia . Journal of Abnormal Psychology , 98 : 367 – 380 .
  • Takano , K. , Ito , M. , Kobayashi , K. , Sonobe , N. , Kurosu , S. Mori , Y. 2002 . Procedural memory in schizophrenia assessed using a mirror reading task . Psychiatry Research , 109 : 303 – 307 .
  • Tombaugh , T. , & Francis , M. ( 1999a ). Same–different experiment [Computer software] . Unpublished test, Carleton University, Ottawa, Ontario, Canada.
  • Tombaugh , T. , & Francis , M. ( 1999b ). Simple reaction time [Computer software] . Unpublished test, Carleton University, Ottawa, Ontario, Canada.
  • Wechsler , D. 1987 . Wechsler Memory Scale—Revised manual , San Antonio, TX : Psychological Corporation .
  • Wechsler , D. 1997 . WAIS-III administration and scoring manual , 3rd ed. , San Antonio, TX : Harcourt Brace & Co .
  • Woodward , N. D. , Purdon , S. E. , Meltzer , H. Y. and Zald , D. H. 2005 . A meta-analysis of neuropsychological change to clozapine, olanzapine, quetiapine, and risperidone in schizophrenia . International Journal of Neuropsychopharmacology , 8 : 457 – 472 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.