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Research Article

A simple HPLC method to determine urinary phenylmercapturic acid and its application to gasoline station attendants to biomonitor occupational exposure to benzene at less than 1 ppm

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Pages 190-203 | Published online: 29 Sep 2008

References

  • AKSOY, M. 1980, Different types of malignancies due to occupational exposure to benzene. A review of recent observations in Turkey. Environmental Research, 1 23, 181–190.
  • AKSOY, M. 1985, Benzene as a leukemogenic and carcinogenic agent. American Journal of Industrial Medicine, 8, 9–20.
  • AMERICAN CONFERENCE OF GOVERNMENTAL INDUSTRIAL HYGIENISTS 2000, Threshold Limit Values and Biological Exposure Indices, 2000 (Cincinnati: ACGIH).
  • ANGERER, J., SCHILDBACH, M. and KRAEMER, A. 1998, Gas chromatographic methods for the simultaneous determination of S-p-toluylmercapturic acid and S-phenylmercapturic acid in human urine. Journal of Analytical Toxicology, 22, 211–214.
  • BOOGAARD, P. J. and VAN SITTERT, N. J. 1995, Biological monitoring of exposure to benzene: a comparison between S-phenylmercapturic acid, trans,trans-muconic acid, and phenol. Occupational and Environmental Medicine, 52, 611–620.
  • BOOGARD, P. J. and VAN SITTERT, N. J. 1996, Suitability of S-phenylmercapturic acid and trans,trans - muconic acid as biomarkers for exposure to low concentrations of benzene. Environmental Health Perspectives, 104 ( Suppl 6), 1151–1157.
  • DE Rom, B. M., COMMANDEUR, J. N. M. and VERMEULEN, N. P E. 1998, Mercapturic acids as biomarkers of exposure to electrophilic chemicals; applications to environmental and industrial chemicals. Biomarkers, 3, 239–303.
  • DEUTSCHE FORSCHUNGSGEMEINSCHAFT 1999, List of M AK and BAT Values, 1999 (Wienheirn: Wiley - VCM).
  • DOR, E, DAB, W., EMPEREUR-BISSONNET, P and ZMIROU, D. 1999, Validity of biomarkers in environmental health studies; in the case of PAHs and benzene. Critical Reviews in Toxicology, 29, 129–168.
  • EINIG, T. and DEHNEN, W. 1995, Sensitive determination of the benzene metabolite S-phenylmercapturic acid in urine by high-performance liquid chromatography with fluorescence detection. Journal of Chromatography A, 697, 371–375.
  • EINIG, T., DUNEMANN, L. and DEHNEN, W 1996, Sensitive gas chromatographic method for determination of mercapturic acids in human urine. Journal of Chromatography B, 687, 379–385.
  • GHITTORI, S., MAESTRI, L., FIORENTINO, M. L. and IMBRIANI, M. 1995, Evaluation of occupational exposure to benzene by urinalysis. International Archives of Occupational and Environmental Health, 67, 195–200.
  • GHITTORI, S., IMBRIANI, M., MAESTRI, L., CAPODAGLIO, E. and CAVALLERI, A. 1999, Determination of S-phenylmercapturic acid in urine as an indicator of exposure to benzene. Toxicology Letters 108, 329–334.
  • HOTZ, P, CARBONNELLE, P, HAUFROID, V., TSCHOPP, A., BUCHET, J. P and LAUWERYS, R. 1997, Biological monitoring of vehicle mechanics and other workers exposed to low concentrations of benzene. International Archives of Occupational and Environmental Health, 70, 29–40.
  • IKEDA, M., KUMAI, M., WATANABE, T. and FUJITA, H. 1984, Aromatic and other contents in automobile gasoline in Japan. Industrial Health, 22, 235–241.
  • INouE, O., SEIJI, K., KASAHARA, M., NAKATSUKA, H., WATANABE, T., YIN, S.-G., LI, G.-L., JIN, C., CAI, S.-X., WANG, X.-Z. and IKEDA, M. 1986, Quantitative relation of urinary phenol levels to breathzone benzene concentrations: a factory survey. British Journal of Industrial Medicine, 43, 692–697.
  • INouE, O., SEIJI, K., KASAHARA, M., NAKATSUKA, H., WATANABE, T., YIN, S.-G., Li, G.-L., CAI, S.-X., JIN, C. and IKEDA, M. 1988a, Determination of catechol and quinol in the urine of workers exposed to benzene. British Journal of Industrial Medicine, 45, 487–492.
  • INouE, O., SEIJI, K., KASAHARA, M., NAKATSUKA, H., WATANABE, T., YIN, S.-G., Li, CAI, S.-X., JIN, C. and IKEDA, M. 1 988b, Mutual metabolic suppression between benzene and toluene in man. International Archives of Occupational and Environmental Health, 60, 15–20.
  • INouE, O., SEIJI, K., KASAHARA, M., NAKATSUKA, H., WATANABE, T., YIN, S.-G., LI, G.-L., CAI, S.-X., JIN, C. and IKEDA, M. 1989a Excretion of 1,2,4-benzenetriol in the urine of workers exposed to benzene. British Journal of Industrial Medicine, 46, 559–565.
  • INouE, O., SEIJI, K. and IKEDA, M. 1 989b, Pathways for formation of catechol and 1,2,4 -benzentriol in rabbits. Bulletin of Environmental Contamination and Toxicology, 43, 444–453.
  • INouE, O., SEIJI, K., KASAHARA, M., NAKATSUKA, H., WATANABE, T., YIN, S.-G., LI, G.-L., CAI, S.-X., JIN, C. and IKEDA, M. 1989c, Urinary t,t-muconic acid as an indicator of exposure to benzene. British Journal of Industrial Medicine, 46, 122–127.
  • INouE, O., KANNO, E., KAKIZAWA, M., WATANABE, T., HIGASHIKAWA, K. and IKEDA, M. 2000, Urinary phenylmercapturic acid as a marker of occupational exposure to benzene. Industrial Health, 38, 195–204.
  • INTERNATIONAL AGENCY FOR RESEARCH ON CANCER 1982, Benzene. IARC Monographs on the Evaluation of Carcinogenic Risks of Chemicals to Humans, No. 29 (Lyon: IARC), pp. 93–148. INTERNATIONAL AGENCY FOR RESEARCH ON CANCER 1987, Benzene IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Suppl. 7 (Lyon: IARC), pp. 120–122.
  • INTERNATIONAL PROGRAMME ON CHEMICAL SAFETY 1993, Environmental Health Criteria No. 150. Benzene (Geneva; WHO), pp. 46–55.
  • JACKSON, S. 1966, Creatinine in urine as an index of urinary excretion rate. Health Physics, 12, 843-850. JAPAN SOCIETY FOR OCCUPATIONAL HEALTH 1999, Recommendation of occupational exposure limits (1 999-2000). Journal of Occupational Health, 41, 191–206.
  • JAVELAUD, B., VIAN, L., MOLLE, R., ALLAIN, P, ALLEMAND, B., ANDRE, B., BARBIER, E, CHURET, A. M., DUPUIS, J., GALAND, M., MILLET, E, TALMON, J., TOURON, C., VAISSIERE, M., VECHAMBRE, D., VIEULES, M. and VIVIER, D. 1998, Benzene exposure in car mechanics and road tanker drivers. International Archives of Occupational and Environmental Health, 71, 277–283.
  • KAWAI, T., YAMAOKA, K., UCHIDA, Y. and IKEDA, M. 1991, Exposure to vapors of benzene and other aromatic solvents in tank truck loading and delivery. Bulletin of Environmental Contamination and Toxicology, 46, 1–8.
  • KAWAI, T., YASUGI, T., MIZUNUMA, K., HORIGUCHI, S., IGUCHI, H., UCHIDA, Y., IwAmi, O. and IKEDA, M. 1992, Comparative evaluation of urinalysis and blood analysis as means of detecting exposure to organic solvents at low concentrations. International Archives of Occupational and Environmental Health, 64, 223–234
  • KIVISTO, H. PEKARI, K., PELTONEN, K., SVINHUFVUD, J., VEIDEBAUM, T., SORSA, M. and AITIO, A. 1997, Biological monitoring of exposure to benzene in the production of benzene and in a cokery. Science of the Total Environment, 199, 49–63.
  • MAESTRI, L., GHITTORI, S., GRIGNANI, E., FIORENTINO, M. L. and IMBRIANI, M. 1993, Dossagio di un metabolita del benzene l'acido S-fenilmercapturico urinario (S-PMA), nell'uomo, mediante HPLC. La Medicina del Lavoro, 84, 55–65 (in Italian with English summary).
  • ONG, C.-N. and LEE, B.-L. 1994, Determination of benzene and its metabolites: application in biological monitoring of environmental and occupational exposure to benzene. Journal of Chromatography B, 600, 1–22.
  • POPP, W., RAUSCHER, D., MUELLER, G., ANGERER, J. and NORPORTH, K. 1994, Concentrations of benzene in blood and S-phenylmercapturic acid in urine in car mechanics. International Archives of Occupational and Environmental Health, 66, 1–6.
  • RAINSFORD, S. G. and LLOYD DAVIES, T. A. 1965, Urinary excretion of phenol by men exposed to vapour of benzene: a screening test. British Journal of Industrial Medicine, 22, 21–26.
  • SABOURIN, P J., BECHTOLD, W E. and HENDERSON, R. E 1988, A high pressure liquid chromatographic method for the separation and quantification of water-soluble radiolabeled benzene metabolites. Analytical Biochemistry, 170, 316–327.
  • STOMMEL, P, MUELLER, G., STUECKER, W. VERKOYEN, C., SCHOEBEL, S. and NORPOTH, K. 1989, Determination of S-phenylmercapturic acid in the urine - an improvement in the biological monitoring of benzene exposure. Carcinogenesis, 10, 279–282.
  • VAN SITTERT, N. J., BOOGAARD, P. J. and BEULINK, G. D. J. 1993, Application of the urinary S-phenylmercapturic acid test as a biomarker for low levels of exposure to benzene in industry. British Journal of Industrial Medicine, 50, 460–469.
  • VERNA, D. K., JOHNSON, D. M. and MCLEAN, J. D. 2000, Benzene and total hydrocarbon exposures in the upstream petroleum oil and gas industry. American Industrial Hygiene Association Journal, 61, 255–263.
  • YIN, S.-N., HAYES, R. B., LINET, M. S., Li, G.-L., DOSEMECI, M., TRAVIS, L. B., Li, C.-Y., ZHANG, Z.-N., Li, D.-G., CHOW, W-H., WACHOLDER, S., WANG, Y.-Z., JIANG, Z.-L., DAI, T.-R., ZHANG, W.-Y., CHAO, X.-J., YE, P.-Z., Kou, Q.-R., ZHANG, X.-C., LIN, X.-E, MENG, J.-E, DING, C.-Y., Zoo, J.-S., and BLOT, W J. 1996, A cohort study of cancer among benzene-exposed workers in China: over-all results. American Journal of Industrial Medicine, 29, 227–235.

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