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Biomarkers Volume 7, 2002 - Issue 2
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Research Article

Development of a urinary biomarker for exposure to the organophosphate propetamphos: data from an oral and dermal human volunteer study

S. J. Garfitt Health Safety Laboratory, Broad Lane, Sheild S3 7HQ, UK
,
K. Jones Health Safety Laboratory, Broad Lane, Sheild S3 7HQ, UK
,
H. J. Mason Health Safety Laboratory, Broad Lane, Sheild S3 7HQ, UK
&
J. Cocker Health Safety Laboratory, Broad Lane, Sheild S3 7HQ, UK
Pages 113-122 | Published online: 29 Sep 2008

  • DROZ, P.O. and FISEROVA-BERGEROVA, V. 1992, Biological monitoring VI. Pharmacokinetic models in setting biological exposure indices. Applied occupational and Environmental Hygiene, 7, 574-580.
  • FENSKE, R. A. and LENCWELL, J. T. 1989, Method for the determination of dialky!phosphate metabolites in urine for studies of human exposure to malathion. Journal of Agriculture and Food Chemistry, 37, 998-1005.
  • GRIFFIN, P., MASON, H. J., HEYWOOD, K. and COCKER, J. 1999, Oral and dermal absorption of chlorpyrifos: a human volunteer study. Occupational and Environmental Medicine, 56, 10-13.
  • HEALTH AND SAFETY EXECUTIVE 2000, Biological Monitoring of Workers Exposed to Organo-Phosphorus Pesticides. MS 17 (Sudbury: HSE Books).
  • HEATH, A. and VALE, J. 1992, Clinical presentation and diagnosis of acute organophosphate insecticide and carbamate poisoning. In Clinical and Experimental Toxicology of Organophosphate and Carbamates, B. Ballantyne and T. Marrs, eds (Oxford: Butterworth), pp. 513-519.
  • JONES, K., WANG, G., GARFITT, S. J. and COCKER, J. 1999, Identification of a biomarker for propetamphos and development of a biological monitoring assay. Biomarkers, 4, 342-350.
  • MASON, H. J. and LEWIS, P. J. 1989, A study of the intra-individual variation in plasma and red cholinesterase activity and its application to the detection of organophosphate pesticides. Journal of Social and occupational Medicine, 39, 121-4.
  • NOLAN, R. J., RICK, D. L., FRESHOUR, N. L. and SAUNDERS, J. H. 1984, Chlorpyrifos: pharmacokinetics in human volunteers. Toxicology and Applied Pharmacology, 73, 8-15.
  • NUTLEY, B. P. and COCKER, J. 1993, Biological monitoring of workers occupationally exposed to organophosphorus pesticides. Pesticide Science, 38, 315-322.

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