Advanced search
Publication Cover
Biomarkers Volume 8, 2003 - Issue 1
Submit an article Journal homepage
267
Views
48
CrossRef citations to date
0
Altmetric
Research Article

Quantification of human intestinal gene expression profiles using exfoliated colonocytes: a pilot study

Laurie A. Davidson Faculty of Nutrition and the Center for Environmental and Rural Health, Texas A&M University, College Station, TX 77843-2471, USA
,
Joanne R. Lupton Faculty of Nutrition and the Center for Environmental and Rural Health, Texas A&M University, College Station, TX 77843-2471, USA
,
Emil Miskovsky Department of Hepatology, University of Texas Medical Branch, Galveston, TX 77555, USA
,
Alan P. Fields Sealy Center for Cancer Cell Biology, University of Texas Medical Branch, Galveston, TX 77555, USA
&
Robert S. Chapkin Faculty of Nutrition and the Center for Environmental and Rural Health, Texas A&M University, College Station, TX 77843-2471, USA
Pages 51-61 | Published online: 29 Sep 2008

  • AGOFF, S. N., BRENTNALL, T. A., CRISIN, D. A., TAYLOR, S. L., RAAKA, S., HAGGITT, R. C., REED, M. W., AFONINA, L. A., RABINOVITCH, P. S., STEVENS, A. C., FENG, Z. And BRONNER, M. P. 2000, The role of cyclooxygenase 2 in ulcerative colitis-associated neoplasia. American Journal of Pathology, 157, 737-745.
  • AHLQUIST, D. A., SKOLETSKY, J. E., BOYNTON, K. A., HARRINGTON, J. J., MAHONEY, D. W., PIERCEALL, W. E., THIBODEAU, S. N. AND SHUBER, A. P. 2000, Colorectal cancer screening by detection of altered human DNA in stool: feasibility of multitarget assay panel. Gastronenterology, 119, 1219-1227.
  • ALBAUGH, G. P., IYENGER, V., LOHANI, A., MALAYERI, M., BALA, S. and NAIR, P. 1992, Isolation of exfoliated colonic epithelial cells; a novel, non-invasive approach to the study of cellular markers, International Journal of Cancer, 52, 347-350.
  • ARBER, N., HIBSCHOOSH, H., MOSS, S. F., SUTTER, M. T., ZHANG, Y., BEGG, M., WANG, S., WEINSTEIN, I. B. and HOLT, P. R., 1996, Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis, Gastroenterology, 110, 669-674.
  • BIASCO, G., PAGANELLI, G. M., MIGLIOLI, M., BRILLANTI, S., D1 FERO, G., GIZZI, G., PONZ DE LEON, M., CAMPIERI, M. and BARBARA, L., 1990. Rectal cell proliferation and colon cancer risk in ulcerative colitis. Cancer Research, 50 1156-1159.
  • BIECHE, L. LAURENDEAU, L. TOZLU, S., OLIVI, M., VIDAUD, D., LIDEREAU, R. and VIDAUD, M. 1990, Quantitation of myc gene expression in sporadig breast tumors with a real-time reverse transcription-PCR assay. Cancer Research, 59, 2759-2765.
  • CAIRNS, P. AND SIDRANSKY, D., 1999, Molecular methods for the diagnosis of cancer. Biochimica et Biophysica Acta, 1423, C11-18.
  • CHAPKIN, R. S., CLARE, A. E., DAVIDSON, L. A., SCHROEDOR, F., ZORAN, D. L. and LUFTON, J. R. 1998, Dietry fiber differentially alters cellular fatty acid-binding protein expression in exfoliated coloncytes during tumor development. Nutrition and Cancer, 32, 107-112.
  • DAVIDSON, L. A., JIANG, Y. H., LUPTON, J. R. and CHAMPKIN, R. S. 1995, Noninvasive detection of putative biomarkers for colon cancer using fecal messenger RNA. Cancer Epidemiology, Biomarkers and Prevention, 4, 643-647.
  • DAVIDSON, L. A., AYMOND, C. M., JIANG, Y. H., TURNER, N. D., LUPTON, J. R. and CHAMPKIN, R. S. 1998, Non-invastive detection of fecal protein kinase C ßII and messenger RNA: putative biomarkers for colon cancer. Carcinogenesis, 19, 253-257.
  • DAVIES, R. J., FREEMAN, A., MORRIS, L. S., BINGHAM, S., DILWORTH, S., SCOTT, I., LASKEY, R. A., MILLER, R. and COLEMAN, N., 2002, Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal concer in stool. Lancet, 359, 1917-1919.
  • DONG, S. M., TRAVERSO, G., JOHNSON, C., GENG, L., FAVIS, R., BOYNTON, K., HIBI, K., GOODMAN, S. N., D'ALLESIO, M., PATY, P., HAMILTON, S. R., SIDRANSKY, D., BARANY, F., LEVIN, B., SHUBER, A., KINZLER, K. W., VOGELSTEIN, B. and JEN, J. 2001, Detecting colorectal cancer in stool with the use of multiple genetic targets. Journal of the National Cancer Institue, 93, 858-865.
  • EBERHART, C. E., COEY, R. J, RAHIKA, A., GIARDIELLO, F. M., FERRENRACH, S. and DUBOIS, R. N. 1994, Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and edenocarcinomas. Gastroenterology, 107, 1183-1188.
  • EL-MAHDANI, N., VAILLANT, J. C., GUIGUET, M., PREVOT, S., BERTRAND, C., PARC, R., BEREZIAT, G. and HERMELIN, B., 1997, Overexpression of p53 rnRNA in colorectal cancer and its relationship to p 53 gene mutation. Britihs Journal of Cancer, 75, 528-536.
  • FEARON, E. R., 1995, Molecular geneties of colorectal cancer. Annals of the New York Academy of Science, 768, 101-110.
  • FELLER, E., 1995, Colon cancer screening: the case for sigmoidoscopy. Rhode Island Medicine, 78, 159-160.
  • GOKMEN-POLAR, Y., MURRAY, N. R., VELASCO, M. A., GATALICA, Z. AND FIELDS, A. P. 2001, Elevated prtein kinase C ßII is an early promotive event in colon carcinogenesis. Cancer Research, 61, 1375-1381.
  • HOWE, L., WINOG, P. A, THUN, M. J., PIES, L. A., ROSENBERG, H. M., FEIGAL, E. G. and ENWARDS, B. K. 2001, Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends. Journal of the National Cancer Institue, 93, 824-842.
  • HUFTON, S. E., MOERKERK, P., BRANDWIJK, R., DE BRUINE, A. P., ARENDS, J.-W. and HOOGENBOON, H. R. 1999, A profile of differentially expressed genes in primary colorectal cancer using suppression subtractive hybridization. FEBS Letters, 463, 77-82.
  • IYENGAR, V., ALBAUGH, G. P., LOHANI, A. and NAIR, P. P. 1991, Human stools as a source of viable colonie epithelial cells. FASEB Journal, 5, 2856-2859.
  • JIANG, Y. H., LUPTON, J. R. and CHAPKIN, R. S. 1997, Dietary fish oil blocks carcinogen-induced down-regulation of colonic protein kinase C isozymes. Carcinogenesis, 18, 351-357.
  • KAWASAKI, H., ALTIER, D. C., LU, C. D., TOYODA, M., TENJO, T. and TANIGAWA, N., 1998, Inhibition of apoptosis by survivin predicts shorter survival rates in colorectal cancer. Cancer Research, 58, 5071-5074.
  • KUTCHERA, W., JONES, D. A., MATSUNAMI, N., GRODEN, J., McINTYRE, T. M., ZIMMERMAN, G. A., WHITE, R. L. and PRESCOTT, S. M. 1996, Prostaglandin H synthase 2 is expressed abnormally in huaman colon cancer: evidence for a transciptional effect. Proceedings of the National Academy of Science of the USA, 93, 4816-4820.
  • LACASSE, E. C., BAIRD, S., KORNELUK, R. G. and MACKENZIE, A. E. 1998, The inhibitors of apoptosis (lAPs) and their emerging role in cancer. Oncogene, 17, 3247-3259.
  • LEVIN, B. and BOND, J. H., 1996, Colorectal cancer screeing: recommendations of the US preventive services task force. Gastraenterology, 111, 1381-1384.
  • LIPSHUTZ, R. J., FODOR, S. P., GINERAS, T. R. and LOCKHART, D. J., 1999, High density synthetic oligonucleotide arrays. Nature Genetics Microarray Supplement, 21, 20-24.
  • MANDE, J. S., 1997, Colorectal cancer screeing. Cancer and Metastasis Review, 16, 263-279.
  • McLEOD, H. L. and MURRAY, G. I. 1999, Tumour markers of prognosis in colorectal cancer. British Journal of Cancer, 79, 191-200.
  • MURRAY, N. R., DAVIDSON, L. A., CHAPKIN, R. S., GUSTAFSON, W. C., SCHATTENBERG, D. G. and FIELDS, A. P., 1999, Overexpression of protein kinase C beta II in the colonic epithelium causes hyperproliferation and increase sensitivity to colon carcinogensis. Journal of Cell Biology, 145, 699-711.
  • PARK, S. I., SAXE, J. C. and WEESNER, R. E., 1993, Does use of Coloscreen self-test improve patient compliance with fecal occult blood screening? American Journal of Gastroenterology, 88, 1391-1394.
  • POTTEN, C. S., SCHOELD, R. and LAJTHA, L. G., 1979, A comparison of cell replacement in bone marrow, testis and three regions of epithelium. Biochemica et Biophysica Acta, 560, 281-290.
  • SIDRANSKY, D. 1997, NUCLEIC ACIDBASED METHODS FOR THE DETECTION OF CANCER. Science, 278, 1054-1058.
  • SIDRANSKY, D., TOKINO, T., HAMILTON, S., KINZLER, K. W., LEVIN, B. FROST, P. AND VOGELSTEIN, B., 1992, Identification of ras-oncogene mutations in the stool of patients with curable colorectal tumors. Science, 256, 3102-3105.
  • TAKAYAMA, T., SHIOZAKI, H., DOKI, Y., OKA, H., INOUE, M. and YAMAMOTO, M., 1998, Aberrant expression and phosphorylation of ß-catenin in human colorectal cancer. British Journal of Cancer, 77, 605-613.
  • VILLA, E., DUGANI, A., REBECCHI, A. M., VIGNOLI, A. GROTTOLA, A., BUTTAFOCO, P., LOSI, L., PERINT, M., TRANDE, P., MERICHI, A., LEROSE, R. and MANENTI, F. 1996, Identification of subjects at risk for colorectal carcinoma through a test based on K-ras determination in the stool. Gastroenterology, 110, 1346-1353.
  • WEINSTEIN, I. B., 1996, Relevance of cyclin D1 and other molecular markers to cancer prevention. Journal of Cellular Biochemistry, 25S. 23-28.
  • WINGO, P. A., TONG, T. and BOLDEN, S., 1995, Cancer statistics. CA: A Cancer Journal for Clinicians, 45, 8-30.
  • WORLD CANCER RESEARCH FUND/AMERICAN INSTITUTE FOR CANCER RESEARCH, 1997, Food, Nutrition and the Prevention of Cancer: A Global Perspective (Wasington, DC: American Institute for Cancer Research).

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.