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Research Article

Identification of interleukin-13 related biomarkers using peripheral blood mononuclear cells

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Pages 414-423 | Received 24 Apr 2006, Published online: 08 Oct 2008

References

  • Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, Taniguchi M, Grusby MJ, DeKruyff RH, Umetsu DT. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergen-induced airway hyperreactivity. Nature Medicine 2003; 9: 582–588
  • Berkman N, Ohnona S, Chung FK, Breuer R. Eotaxin-3 but not eotaxin gene expression is upregulated in asthmatics 24 hours after allergen challenge. American Journal of Respiratory Cell and Molecular Biology 2001; 24: 682–687
  • Brutsche MH, Joos L, Carlen Brutsche IEA, Bissinger R, Tamm M, Custovic A, Woodcock A. Array-based diagnostic gene-expression score for atopy and asthma. Journal of Allergy and Clinical Immunology 2002; 109: 271–273
  • Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, Rennick DM, Sheppard D, Mohrs M, Donaldson DD, Locksley RM, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998; 28: 22261–2263
  • Hansel NN, Hilmer SC, Georas SN, Cope LM, Guo J, Irizarry RA, Diette GB. Oligonucleotide-microarray analysis of peripheral-blood lymphocytes in severe asthma. Journal of Laboratory and Clinical Medicine 2005; 145: 263–274
  • Hijnen D, de Bruin-Weller M, Oosting B, Lebre C, de Jong E, Bruijnzeel-Koomen C, Knol E. Serum thymus and activation-regulated chemokine (TARC) and cutaneous T cell-attracting chemokine (CTACK) levels in allergic diseases: TARC and CTACK are disease-specific markers for atopic dermatitis. Journal of Allergy and Clinical Immunology 2004; 113: 334–340
  • Hilton DJ, Zhang J-G, Metcalf D, Alexander WS, Nicola NA, Willson TA. Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor. Proceedings of the National Academy of Sciences 1996; 93: 497–501
  • Holgate S. The epidemic of allergy and asthma. Nature 1999; 402: B2–B4
  • Lee JH, Kaminski N, Dolganov G, Grunig G, Koth L, Solomon C, Erle DJ, Sheppard D. Interleukin-13 induces dramatically different transcriptional programs in three human airway cell types. American Journal of Respiratory Cell and Molecular Biology 2001; 25: 474–485
  • Leung TF, Wong CK, Lam CWK, Li AM, Ip WK, Wong GWK, Fok TF. Plasma TARC concentration may be a useful marker for asthmatic exacerbation in children. European Respiratory Journal 2003; 21: 616–620
  • Pilette C, Francis JN, Till SJ, Durham SR. CCR4 ligands are up-regulated in the airways of atopic asthmatics after segmental allergen challenge. European Respiratory Journal 2004; 23: 876–884
  • Prieto J, Lensmar C, Roquet A, van der Ploeg I, Gigliotti D, Eklund A, Grunewald J. Increased interleukin-13 mRNA expression in bronchoalveolar lavage cells of atopic patients with mild asthma after repeated low-dose allergen provocations. Respiratory Medicine 2000; 94: 806–814
  • Sekiya T, Yamada H, Yamaguchi M, Yamamoto K, Ishii A, Yoshie O, Sano Y, Morita A, Matsushima K, Hirai K. Increased levels of a TH2-type CC chemokine thymus and activation-regulated chemokine (TARC) in serum and induced sputum of asthmatics. Allergy 2002; 57: 173–177
  • Syed F, Blakemore SJ, Wallace DM, Trower MK, Johnson M, Markham AF, Morrison JFJ. CCR7 (EBI1) receptor down-regulation in asthma: differential gene expression in human CD4+ T lymphocytes. QJM 1999; 92: 463–471
  • Syed F, Panettieri R, Tliba O, Huang C, Li K, Bracht M, Amegadzie B, Griswold D, Li L, Amrani Y. The effect of IL-13 and IL-13R130Q, a naturally occurring IL-13 polymorphism, on the gene expression of human airway smooth muscle cells. Respiratory Research 2005; 6: 9
  • Venkayya R, Lam M, Willkom M, Grunig G, Corry DB, Erle DJ. The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells. American Journal of Respiratory Cell and Molecular Biology 2002; 26: 202–208
  • Walter DM, McIntire JJ, Berry G, McKenzie ANJ, Donaldson DD, DeKruyff RH, Umetsu DT. Critical role for IL-13 in the development of allergen-induced airway hyperreactivity. Journal of Immunology 2001; 167: 4668–4675
  • Wills-Karp M. Interleukin-13 in asthma pathogenesis. Immunological Reviews 2004; 202: 175–190
  • Wills-Karp M, Luyimbazi J, Xu X, Schofield B, Neben TY, Karp CL, Donaldson DD. Interleukin-13: central mediator of allergic asthma. Science 1998; 282: 2258–2261
  • Yang G, Li L, Volk A, Emmell E, Petley T, Giles-Komar J, Rafferty P, Lakshminarayanan M, Griswold DE, Bugelski PJ, et al. Therapeutic dosing with anti-interleukin-13 monoclonal antibody inhibits asthma progression in mice. Journal of Pharmacology and Experimental Therapeutics 2005; 313: 8–15
  • Yang G, Volk A, Petley T, Emmell E, Giles-Komar J, Shang X, Li J, Das AM, Shealy D, Griswold DE, et al. Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling. Cytokine 2004; 28: 224–232
  • Yuyama N, Davies DE, Akaiwa M, Matsui K, Hamasaki Y, Suminami Y, Yoshida NL, Maeda M, Pandit A, Lordan JL. Analysis of novel disease-related genes in bronchial asthma. Cytokine 2002; 19: 287–296
  • Zimmermann N, King NE, Laporte J, Yang M, Mishra A, Pope SM, Muntel EE, Witte DP, Pegg AA, Foster PS, et al. Dissection of experimental asthma with DNA microarray analysis identifies arginase in asthma pathogenesis. Journal of Clinical Investigation 2003; 111: 1863–1874
  • Zou J, Young S, Zhu F, Gheyas F, Skeans S, Wan Y, Wang L, Ding W, Billah M, McClanahan T, , et al. 2002. Microarray profile of differentially expressed genes in a monkey model of allergic asthma. Genome Biology 3:research0020.1– research0020.13.

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