Persistence of 7-(2-hydroxyethyl) guanine-DNA adducts in rats exposed to ethene by inhalation

References

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• KUMAR, R. AND HEMMINKI, K. (1996) Separation of 7-methyl- and 7-(2-hydroxyethyl)-guanine adducts in human DNA samples using a combination of TLC and HPLC. Carcinogenesis, 17, 485–492.
   PubMed Web of Science ®Google Scholar
• KUMAR, R., STAFFAS, J., FORS-n, A. AND HEMMINKI, K. (1995)32P-postlabelling method for the detection of 7-alkylguanine adducts formed by the reaction of different 1,2-alkyl expoxides with DNA. Carcinogenesis, 16,483–489.
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• KUMAR, R., VODICKA, P., Komsm, P., PELTONEN, K. AND HEMMINKI, K. (1996)32P-Postlabelling of diastereomeric 7-alkylguanine adducts of butadiene monoepoxide. Carcinogenesis, 17, 1297–1303.
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   PubMed Web of Science ®Google Scholar
• SEGERBACK, D. (1983) Alkylation of DNA and haemoglobin in the mouse following exposure to ethene and ethene oxide. Chemico-Biological Interactions, 45, 139–151.
   PubMed Web of Science ®Google Scholar
• SEGERBACK, D. (1985) In vivo dosimetry of some alkylating agents as a basis for risk estimation. PhD thesis, Stockholm University.
   Google Scholar
• SEGERBACK, D. (1990) Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea. Carcinogenesis, 11, 307–312.
   PubMed Web of Science ®Google Scholar
• SHUKER, D. E. G. AND BARTSCH, H. (1994) DNA adducts of nitrosamines. In DNA-adducts—Identification and Biological significance, K. Hem minki, A. Dipple, D. E. G. Shuker, F. F. Kadlubar, D. Segerbäck and H. Bartsch, eds, IARC Scieniffic Publication No. 125 (IARC, Lyon, France), pp. 73–89.
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   Google Scholar
• TORNQVIST, M., GUSTAFSSON, B., KAUTIAINEN, A., HAIMS-RINGDAHL, M., GRANATH, F. AND EHRENBERG, L. (1989) Unsaturated lipids and intestinal bacteria as sources of endogenous production of ethene and ethylene oxide. Carcinogenesis, 10,39–41.
   Google Scholar
• VAN DELFT, J. H. M., VAN WINDEN, M. J. M., LUITEN-SCHUITE, A., RIBEIRO, L. R. AND BAAN, R. A. (1994) Comparison of various immunochemical assays for the detection of ethylene oxide—DNA adducts with monoclonal antibodies against imidazole ring opened N7-(2-hydroxyethyl)guanosine: application in a biological montoring study. Carcinogenesis, 15, 1867–1994.
   Web of Science ®Google Scholar
• WALKER, V. E., FENNELL, T. R., BOUCHERON, J. A., FEDTKE, N., CIROUSSEL, F. AND SWENBERG, J. A. (1990) Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation. Mutation Research, 233, 151–164.
   PubMedGoogle Scholar
• WALKER, V. E., FENNELL, T. R., UPTON, P. B., SKOPEK, T. R., PREVOST, V., SHUKER, D. E. G. AND SWENBERG, J. A. (1992) Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice. Cancer Research, 52, 4328–4334.
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• WDLAK, P., ZHENG, X., OSTERDAHL, B., DRETTNER, B., CHRISTENSSON, B., KUMAR, R. AND HEMMINKI, K. (1995) N-Nitrosodimethylamine and 7-methylguanine DNA adducts in tissues of rats fed Chinese salted fish. Cancer Letters, 94, 85–90.
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• Received 7 May 1997, revised form accepted 26 June 1997
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• BARROWS, L. R. AND MAGEE, P. N. (1982) Nonenzymatic methylation of DNA by S-adenosylmethionine in vitro. Carcinogenesis, 3, 349–351.
   PubMedGoogle Scholar
• BOSTROM, C. E., ALmEN, J., STEEN, B. AND WESTERHOLM, R. (1994) Human exposure to urban air pollution. Environmental Health Perspectives, 102 (Suppl. 4), 39–47.
   PubMedGoogle Scholar
• EIDE, I., HAGEMANN, R., ZAHLSEN, K., TAREKE, E., TORNQVIST, M., KUMAR, R., VODICKA, P. AND HEMMINKI, K. (1995) Uptake, distribution, and formation of hemoglobin and DNA adducts after inhalation of C2—C8 1-alkenes (olefins) in the rat. Carcinogenesis, 16, 1603–1609.
   Google Scholar
• FOST, U., MARCZYNSKI, B., KASEMANN, R. AND PETER, H. (1989) Determination of 7-(2-hydroxyethyl)guanine with gas chromatography/mass spectrometry as a parameter for genotoxicity of ethylene oxide. Archives of Toxicology, (Suppl. 13), 250–253.
   PubMedGoogle Scholar
• GUPTA, R. C. (1982) Nonrandom binding of the carcinogen N-hydrox-2-acetylaminofluorene to repetitive sequences of rat liver DNA in vivo. Proceedings of the National Academy of Sciences of the United States of America, 81, 6943–6947.
   Web of Science ®Google Scholar
• HABRAKEN, Y., CARTER, C. A., KIRK, M. C., AND LUDLUM, D. B. (1991) Release of 7-alkylguanines from N-(2-chloroethyl)-W-cyclohexyl-N-nitrosourea-modified DNA by 3-methyladenine DNA glycosylase II. Cancer Research, 51, 499–503.
   PubMed Web of Science ®Google Scholar
• INTERNATIONAL AGENCY FOR RESEARCH ON CANCER (1994) Some industrial chemicals. In IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 60 (IARC, Lyon, France).
   Google Scholar
• KAUTIAINEN, A., MIDTVEDT, T. AND TORNQVIST, M. (1993) Intestinal bacteria and endogenous production of malonaldehyde and alkylators in mice. Carcinogenesis, 14, 2633–2636.
   PubMed Web of Science ®Google Scholar
• KOEPKE, S. R., KROEGER-KOEPKE, M. P., BOSAN, W., THOMAS, B. J., ALVORD, W. G. AND MICHEJDA, A. (1988) Alkylation of DNA in rats by N-nitrosomethyl-(2-hydroxyethyl)amine: dose response and persistence of the aklated lesions in vivo. Cancer Research, 48, 1537–1542.
   Google Scholar
• KUMAR, R. AND HEMMINKI, K. (1996) Separation of 7-methyl- and 7-(2-hydroxyethyl)-guanine adducts in human DNA samples using a combination of TLC and HPLC. Carcinogenesis, 17, 485–492.
   PubMed Web of Science ®Google Scholar
• KUMAR, R., STAFFAS, J., FORS-n, A. AND HEMMINKI, K. (1995)32P-postlabelling method for the detection of 7-alkylguanine adducts formed by the reaction of different 1,2-alkyl expoxides with DNA. Carcinogenesis, 16,483–489.
   Google Scholar
• KUMAR, R., VODICKA, P., Komsm, P., PELTONEN, K. AND HEMMINKI, K. (1996)32P-Postlabelling of diastereomeric 7-alkylguanine adducts of butadiene monoepoxide. Carcinogenesis, 17, 1297–1303.
   PubMed Web of Science ®Google Scholar
• LUDEKE, B. I. AND KLEIHUES, P. (1988) Formation and persistence of 06(2-hydroxyethyl)-2-deoxyguanosine in DNA of various tissues following a single dose of N-nitroso-N-(2-hydroxyethyl)urea, an immuno-slot-blot study. Carcinogenesis, 9, 147–151.
   PubMed Web of Science ®Google Scholar
• NASLUND, M., SEGERBACK, D. AND KOLMAN, A. (1983) S-adenosylmethionine, an endogenous alkylating agent. Mutation Research, 119, 229–232.
   PubMedGoogle Scholar
• OSTERMAN-GOLKAR, S., FARMER, P. B., SEGERBACK, D., BAILEY, E., CALLEMAN, C. J., SVENSSON, K. AND EHRENBERG, L. (1983) Dosimetry of ethylene oxide in the rat by quantitation of alkylated histidine in hemoglobin. Teratogenesis, Carcinogenesis, and Muta genesis, 3, 395–405.
   Google Scholar
• POTTER, D., BLAIR, D., DAVIES, R., WATSON, W. P. AND WRIGHT, A. S. (1989) The relationships between alkylation of haemoglobin and DNA in Fischer 344 rats exposed to ['4C]ethylene oxide. Archives of Toxicology, (Suppl. 13), 254–257.
   PubMedGoogle Scholar
• RYDBERG, B. AND LINDAHL, T. (1982) Nonenzymatic methylation of DNA by the intracellular methyl group donor S-adenosyl-L-methionine is a potentially mutagenic reaction. EMBO Journal, 1, 211–216.
   PubMed Web of Science ®Google Scholar
• SEGERBACK, D. (1983) Alkylation of DNA and haemoglobin in the mouse following exposure to ethene and ethene oxide. Chemico-Biological Interactions, 45, 139–151.
   PubMed Web of Science ®Google Scholar
• SEGERBACK, D. (1985) In vivo dosimetry of some alkylating agents as a basis for risk estimation. PhD thesis, Stockholm University.
   Google Scholar
• SEGERBACK, D. (1990) Reaction products in hemoglobin and DNA after in vitro treatment with ethylene oxide and N-(2-hydroxyethyl)-N-nitrosourea. Carcinogenesis, 11, 307–312.
   PubMed Web of Science ®Google Scholar
• SHUKER, D. E. G. AND BARTSCH, H. (1994) DNA adducts of nitrosamines. In DNA-adducts—Identification and Biological significance, K. Hem minki, A. Dipple, D. E. G. Shuker, F. F. Kadlubar, D. Segerbäck and H. Bartsch, eds, IARC Scieniffic Publication No. 125 (IARC, Lyon, France), pp. 73–89.
   Google Scholar
• SIPES, I. G. AND GANDOLFI, A. J. (1991) Biotransformation of toxicants. In Casarett and Doulls Yoxicology, 4th edition, M. O. Amdur, J. Doull and C. D. Klaassen, eds (Pergamon Press, New York), pp. 88–126.
   Google Scholar
• SWENBERG, J. A., LA, D. A., SCHELLER, N. A. AND WU, K. (1995) Dose—response relationships for carcinogens. Toxicology Letters, 82/83, 751–756.
   Google Scholar
• TAKESHITA, M. AND EISENBERG, W. (1994) Mechanism of mutation on DNA templates containing synthetic abasic sites: study with a double strand vector. Nucleic Acids Research, 22, 1897–1902.
   PubMed Web of Science ®Google Scholar
• TORNQVIST, M. (1988) Hemoglobin adducts in animals exposed to gasoline and diesel exhausts, 1. Alkenes. Journal of Applied Toxicology, 8, 159-170. TORNQVIST, M., OSTERMAN-GOLKAR, S., KAUTIAINEN, A., JENSEN, S., FARMER, P. B. AND EHRENBERG, L. (1986) Tissue doses of ethylene oxide in cigarette smokers determined from adduct levels in hemoglobin. Carcinogenesis, 7, 1519–1521.
   Google Scholar
• TORNQVIST, M., GUSTAFSSON, B., KAUTIAINEN, A., HAIMS-RINGDAHL, M., GRANATH, F. AND EHRENBERG, L. (1989) Unsaturated lipids and intestinal bacteria as sources of endogenous production of ethene and ethylene oxide. Carcinogenesis, 10,39–41.
   Google Scholar
• VAN DELFT, J. H. M., VAN WINDEN, M. J. M., LUITEN-SCHUITE, A., RIBEIRO, L. R. AND BAAN, R. A. (1994) Comparison of various immunochemical assays for the detection of ethylene oxide—DNA adducts with monoclonal antibodies against imidazole ring opened N7-(2-hydroxyethyl)guanosine: application in a biological montoring study. Carcinogenesis, 15, 1867–1994. WALKER, V. E., FENNELL, T. R., BOUCHERON, J. A., FEDTKE, N., CIROUSSEL, F. AND SWENBERG, J. A. (1990) Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation. Mutation Research, 233, 151–164.
   Google Scholar
• WALKER, V. E., FENNELL, T. R., UPTON, P. B., SKOPEK, T. R., PREVOST, V., SHUKER, D. E. G. AND SWENBERG, J. A. (1992) Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice. Cancer Research, 52, 4328–4334.
   Google Scholar
• WDLAK, P., ZHENG, X., OSTERDAHL, B., DRETTNER, B., CHRISTENSSON, B., KUMAR, R. AND HEMMINKI, K. (1995) N-Nitrosodimethylamine and 7-methylguanine DNA adducts in tissues of rats fed Chinese salted fish. Cancer Letters, 94, 85–90.
   PubMed Web of Science ®Google Scholar