Aberrant methylation of nucleotide excision repair genes is associated with chronic arsenic poisoning

References

• Aboussekhra A, Biggerstaff M, Shivji MK, et al. (1995). Mammalian DNA nucleotide excision repair reconstituted with purified protein components. Cell 80:859–68.
   PubMed Web of Science ®Google Scholar
• Ahlborn GJ, Nelson GM, Ward WO, et al. (2008). Dose response evaluation of gene expression profiles in the skin of K6/ODC mice exposed to sodium arsenite. Toxicol Appl Pharm 227:400–16.
   PubMed Web of Science ®Google Scholar
• Andrew AS, Burgess JL, Meza MM, et al. (2006). Arsenic exposure is associated with decreased DNA repair in vitro and in individuals exposed to drinking water arsenic. Environ Health Persp 114:1193–8.
   PubMed Web of Science ®Google Scholar
• Andrew AS, Karagas MR, Hamilton JW, et al. (2003). Decreased DNA repair gene expression among individuals exposed to arsenic in United States drinking water. Int J Cancer 104:263–8.
   PubMed Web of Science ®Google Scholar
• Applebaum KM, Karagas MR, Hunter DJ, et al. (2007). Polymorphisms in nucleotide excision repair genes, arsenic exposure, and non-melanoma skin cancer in New Hampshire. Environ Health Persp 115:231–6.
   PubMed Web of Science ®Google Scholar
• Bach J, Peremartí J, Annangi B, et al. (2015). Reduced cellular DNA repair capacity after environmentally relevant arsenic exposure. Influence of Ogg1 deficiency. Mutat Res Fund Mol Mech Mut 779:144–51.
   PubMed Web of Science ®Google Scholar
• Banerjee M, Sarma N, Biswas R, et al. (2008). DNA repair deficiency leads to susceptibility to develop arsenic-induced premalignant skin lesions. Int J Cancer 123:283–7.
   PubMed Web of Science ®Google Scholar
• Baoshan Z, Binbin W, Zhenhua D, et al. (2005). Endemic arsenosis caused by indoor combustion of high-As coal in Guizhou Province, PR China. Environ Geochem Health 27:521–8.
   PubMed Web of Science ®Google Scholar
• Belkin H, Zheng B, Finkelman R. (1997). Geochemistry of coal and endemic arsenism in Southwest Guizhou, China. US Geological survey open file report No. 97-496.
   Google Scholar
• Belkin HE, Zheng B, Zhou D, et al. (2008). Chronic arsenic poisoning from domestic combustion of coal in rural China: a case study of the relationship between earth materials and human health. In: De Vivo B, Belkin HE, Lima A, editors. Environmental geochemistry: site characterization, data analysis and case histories. Oxford: Elsevier, 401–20.
   Google Scholar
• Benbrahim-Tallaa L, Waterland RA, Styblo M, et al. (2005). Molecular events associated with arsenic-induced malignant transformation of human prostatic epithelial cells: aberrant genomic DNA methylation and K-ras oncogene activation. Toxicol Appl Pharm 206:288–98.
   PubMed Web of Science ®Google Scholar
• Boonchai W, Walsh M, Cummings M, et al. (2000). Expression of p53 in arsenic-related and sporadic basal cell carcinoma. Arch Dermatol 136:195–8.
   PubMedGoogle Scholar
• Carmichael J, DeGraff WG, Gazdar AF, et al. (1987). Evaluation of a tetrazolium-based semiautomated colorimetric assay: assessment of chemosensitivity testing. Cancer Res 47:936–42.
   PubMed Web of Science ®Google Scholar
• Chai CY, Huang YC, Hung WC, et al. (2007). Arsenic salt-induced DNA damage and expression of mutant p53 and COX-2 proteins in SV-40 immortalized human uroepithelial cells. Mutagenesis 22:403–8.
   PubMed Web of Science ®Google Scholar
• Chanda S, Dasgupta UB, Guhamazumder D, et al. (2006). DNA hypermethylation of promoter of gene p53 and p16 in arsenic-exposed people with and without malignancy. Toxicol Sci 89:431–7.
   PubMed Web of Science ®Google Scholar
• Chen H, Li S, Liu J, et al. (2004). Chronic inorganic arsenic exposure induces hepatic global and individual gene hypomethylation: implications for arsenic hepatocarcinogenesis. Carcinogenesis 25:1779–86.
   PubMed Web of Science ®Google Scholar
• Chen WT, Hung WC, Kang WY, et al. (2007). Urothelial carcinomas arising in arsenic-contaminated areas are associated with hypermethylation of the gene promoter of the death-associated protein kinase. Histopathology 51:785–92.
   PubMed Web of Science ®Google Scholar
• Coppin J-F, Qu W, Waalkes MP. (2008). Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells. J Biol Chem 283:19342–50.
   PubMed Web of Science ®Google Scholar
• Cui X, Wakai T, Shirai Y, et al. (2006a). Chronic oral exposure to inorganic arsenate interferes with methylation status of p16INK4a and RASSF1A and induces lung cancer in A/J mice. Toxicol Sci 91:372–81.
   PubMed Web of Science ®Google Scholar
• Cui X, Wakai T, Shirai Y, et al. (2006b). Arsenic trioxide inhibits DNA methyltransferase and restores methylation-silenced genes in human liver cancer cells. Hum Pathol 37:298–311.
   PubMed Web of Science ®Google Scholar
• De Boer J, Hoeijmakers JH. (2000). Nucleotide excision repair and human syndromes. Carcinogenesis 21:453–60.
   PubMed Web of Science ®Google Scholar
• Finkelman RB. (2007). Health impacts of coal: facts and fallacies. AMBIO 36:103–6.
   PubMed Web of Science ®Google Scholar
• Finkelman RB, Belkin HE, Centeno JA, et al. (2003). Geological epidemiology: coal combustion in China. In: Skinner HC, Berger AR, eds. Geology and health: closing the gap. Oxford: Oxford University Press, 45–50.
   Google Scholar
• Finkelman RB, Belkin HE, Zheng B. (1999). Health impacts of domestic coal use in China. Proc Natl Acad Sci USA 96:3427–31.
   PubMed Web of Science ®Google Scholar
• Finkelman RB, Greb SF. (2008). Environmental and health impacts. In: Suárez-Ruiz I, Crelling JC, editors. Applied coal petrology—the role of petrology in coal utilization. Oxford: Elsevier, 263–87.
   Google Scholar
• Flora S, Bhadauria S, Kannan G, et al. (2007). Arsenic induced oxidative stress and the role of antioxidant supplementation during chelation: a review. J Environ Biol 28:333–47.
   PubMed Web of Science ®Google Scholar
• Hossain MB, Vahter M, Concha G, et al. (2012). Environmental arsenic exposure and DNA methylation of the tumor suppressor gene p16 and the DNA repair gene MLH1: effect of arsenic metabolism and genotype. Metallomics 4:1167–75.
   PubMed Web of Science ®Google Scholar
• Hunt KM, Srivastava RK, Elmets CA, et al. (2014). The mechanistic basis of arsenicosis: pathogenesis of skin cancer. Cancer Lett 354:211–19.
   PubMed Web of Science ®Google Scholar
• IARC. (2012). IARC monographs on the evaluation of carcinogenic risks to humans: arsenic, metals, fibers and dusts. Vol. 100 (C). Lyon, France: IARC.
   Google Scholar
• Jaspers NG, Raams A, Silengo MC, et al. (2007). First reported patient with human ERCC1 deficiency has cerebro-oculo-facio-skeletal syndrome with a mild defect in nucleotide excision repair and severe developmental failure. Am J Hum Genet 80:457–66.
   PubMed Web of Science ®Google Scholar
• Jensen TJ, Novak P, Eblin KE, et al. (2008). Epigenetic remodeling during arsenical-induced malignant transformation. Carcinogenesis 29:1500–8.
   PubMed Web of Science ®Google Scholar
• Li C, Yin M, Wang L-E, et al. (2013). Polymorphisms of nucleotide excision repair genes predict melanoma survival. J Invest Dermatol 133:1813–21.
   PubMed Web of Science ®Google Scholar
• Lin GF, Du H, Chen JG, et al. (2010). Association of XPD/ERCC2 G23591A and A35931C polymorphisms with skin lesion prevalence in a multiethnic, arseniasis-hyperendemic village exposed to indoor combustion of high arsenic coal. Arch Toxicol 84:17–24.
   PubMed Web of Science ®Google Scholar
• Liu J, Zheng B, Aposhian HV, et al. (2002). Chronic arsenic poisoning from burning high‐arsenic‐containing coal in Guizhou, China. Environ Health Perspect 110:119–22.
   PubMed Web of Science ®Google Scholar
• Liu SX, Athar M, Lippai I, et al. (2001). Induction of oxyradicals by arsenic: implication for mechanism of genotoxicity. Proc Natl Acad Sci USA 98:1643–8.
   PubMed Web of Science ®Google Scholar
• Lu G, Xu H, Chang D, et al. (2014). Arsenic exposure is associated with DNA hypermethylation of the tumor suppressor gene p16. J Occup Med Toxicol 9:1–5.
   PubMed Web of Science ®Google Scholar
• Lunn RM, Helzlsouer KJ, Parshad R, et al. (2000). XPD polymorphisms: effects on DNA repair proficiency. Carcinogenesis 21:551–5.
   PubMed Web of Science ®Google Scholar
• Ma L, Li J, Zhan Z, et al. (2016). Specific histone modification responds to arsenic-induced oxidative stress. Toxicol Appl Pharmacol 302:52–61.
   PubMed Web of Science ®Google Scholar
• Marsit CJ, Karagas MR, Danaee H, et al. (2005). Carcinogen exposure and gene promoter hypermethylation in bladder cancer. Carcinogenesis 27:112–16.
   PubMed Web of Science ®Google Scholar
• Moore LE, Smith AH, Eng C, et al. (2002). Arsenic-related chromosomal alterations in bladder cancer. J Natl Cancer Inst 94:1688–96.
   PubMedGoogle Scholar
• Nollen M, Ebert F, Moser J, et al. (2009). Impact of arsenic on nucleotide excision repair: XPC function, protein level, and gene expression. Mol Nutr Food Res 53:572–82.
   PubMed Web of Science ®Google Scholar
• Paul S, Banerjee N, Chatterjee A, et al. (2014). Arsenic-induced promoter hypomethylation and over-expression of ERCC2 reduces DNA repair capacity in humans by non-disjunction of the ERCC2-Cdk7 complex. Metallomics 6:864–73.
   PubMed Web of Science ®Google Scholar
• Ramirez P, Del Razo L, Gutierrez-Ruiz M, et al. (2000). Arsenite induces DNA-protein crosslinks and cytokeratin expression in the WRL-68 human hepatic cell line. Carcinogenesis 21:701–6.
   PubMed Web of Science ®Google Scholar
• Razin A, Riggs AD. (1980). DNA methylation and gene function. Science 210:604–10.
   PubMed Web of Science ®Google Scholar
• Reichard JF, Schnekenburger M, Puga A. (2007). Long term low-dose arsenic exposure induces loss of DNA methylation. Biochem Biophys Res Commun 352:188–92.
   PubMed Web of Science ®Google Scholar
• Ren X, Mchale CM, Skibola CF, et al. (2010). An emerging role for epigenetic dysregulation in arsenic toxicity and carcinogenesis. Environ Health Perspect 119:11–19.
   PubMed Web of Science ®Google Scholar
• Shen S, Lee J. Weinfeld, et al. (2008). Attenuation of DNA damage-induced p53 expression by arsenic: a possible mechanism for arsenic co-carcinogenesis. Mol Carcinog 47:508–18.
   PubMed Web of Science ®Google Scholar
• Singh NP, McCoy MT, Tice RR, et al. (1988). A simple technique for quantitation of low levels of DNA damage in individual cells. Exp Cell Res 175:184–91.
   PubMed Web of Science ®Google Scholar
• Smith AH, Hopenhayn‐Rich C, Warner M, et al. (1993). Rationale for selecting exfoliated bladder cell micronuclei as potential biomarkers for arsenic genotoxicity. J Toxicol Environ Health 40:223–34.
   PubMed Web of Science ®Google Scholar
• Takahashi M, Barrett JC, Tsutsui T. (2002). Transformation by inorganic arsenic compounds of normal Syrian hamster embryo cells into a neoplastic state in which they become anchorage‐independent and cause tumors in newborn hamsters. Int J Cancer 99:629–34.
   PubMed Web of Science ®Google Scholar
• Tsuda H, Takarabe T, Kanai Y, et al. (2002). Correlation of DNA hypomethylation at pericentromeric heterochromatin regions of chromosomes 16 and 1 with histological features and chromosomal abnormalities of human breast carcinomas. Am J Pathol 161:859–66.
   PubMed Web of Science ®Google Scholar
• Ying S, Myers K, Bottomley S, et al. (2009). BRCA2-dependent homologous recombination is required for repair of Arsenite-induced replication lesions in mammalian cells. Nucleic Acids Res 37:5105–13.
   PubMed Web of Science ®Google Scholar
• Zhang A, Feng H, Yang G, et al. (2007b). Unventilated indoor coal-fired stoves in Guizhou province, China: cellular and genetic damage in villagers exposed to arsenic in food and air. Environ Health Perspect 115:653–8.
   PubMed Web of Science ®Google Scholar
• Zhang A, Gao C, Han X, et al. (2014). Inactivation of p15INK4b in chronic arsenic poisoning cases. Toxicol Rep 1:692–8.
   Google Scholar
• Zhang A-H, Bin H-H, Pan X-L, et al. (2007a). Analysis of p16 gene mutation, deletion and methylation in patients with arseniasis produced by indoor unventilated-stove coal usage in Guizhou, China. J Toxicol Environ Health 70:970–5.
   PubMed Web of Science ®Google Scholar
• Zhou X, Sun H, Ellen TP, et al. (2008). Arsenite alters global histone H3 methylation. Carcinogenesis 29:1831–6.
   PubMed Web of Science ®Google Scholar