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Biomarkers Volume 26, 2021 - Issue 3
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Original Articles

Role of biomarkers CA-125, CA-15.3 and CA-19.9 in the distinction between endometriomas and ovarian neoplasms

Jéssica de Souza MagalhãesResearch Institute of Oncology (IPON), Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil
,
Millena Prata JammalResearch Institute of Oncology (IPON), Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil
,
Paula Carolina Arvelos CrispimResearch Institute of Oncology (IPON), Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil
,
Eddie Fernando Candido MurtaResearch Institute of Oncology (IPON), Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, Brazil
&
Rosekeila Simões NomeliniResearch Institute of Oncology (IPON), Department of Gynecology and Obstetrics, Federal University of Triângulo Mineiro, Uberaba, MG, BrazilCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6591-7619
ORCID Icon
Pages 268-274 | Received 12 Aug 2020, Accepted 27 Jan 2021, Published online: 16 Feb 2021

References

  • Bast, R.C., Jr., et al., 1983. A radioimmunoassay using a monoclonal antibody to monitor the course of epithelial ovarian cancer. The new England journal of medicine, 309 (15), 883–887.
  • Berg, E.L., et al., 1991. A carbohydrate domain common to both sialyl Le(a) and sialyl Le(X) is recognized by the endothelial cell leukocyte adhesion molecule ELAM-1. The journal of biological chemistry, 266 (23), 14869–14872.
  • Chapron, C., et al., 2019. Rethinking mechanisms, diagnosis and management of endometriosis. Nature reviews. Endocrinology, 15 (11), 666–682.
  • Chew, K.T., et al., 2018. Elevated serum CA 19-9 with adnexal mass: is it always an Ovarian malignancy? Hormone molecular biology and clinical, 34 (3), 1–3.
  • Cranney, R., Condous, G., and Reid, S., 2017. An update on the diagnosis, surgical management, and fertility outcomes for women with endometrioma. Acta obstetricia et gynecologica scandinavica, 96 (6), 633–643.
  • Dochez, V., et al., 2019. Biomarkers and algorithms for diagnosis of ovarian cancer: CA125, HE4, RMI and ROMA, a review. Journal of Ovarian research, 12 (1), 28.
  • Du Bois, A., et al., 2009. Role of surgical outcome as prognostic factor in advanced epithelial ovarian cancer: a combined exploratory analysis of 3 prospectively randomized phase 3 multicenter trials: by the Arbeitsgemeinschaft Gynaekologische Onkologie Studiengruppe Ovarialkarzinom (AGO-OVAR) and the Groupe d’Investigateurs Nationaux Pour les Etudes des Cancers de l’Ovaire (GINECO). Cancer, 115 (6), 1234–1244.
  • Fiala, L., Bob, P., and Raboch, J., 2018. Oncological markers CA-125, CA 19-9 and endometriosis. Medicine, 97 (51), e13759.
  • Harada, T., Kubota, T., and Aso, T., 2002. Usefulness of CA19-9 versus CA125 for the diagnosis of endometriosis. Fertility and sterility, 78 (4), 733–739.
  • Khodaverdi, S., et al., 2018. Adnexal mass with extremely high levels of CA-125 and CA19-9 but normal Human Epididymis Protein 4 (HE4) and Risk of Ovarian Malignancy Algorithm (ROMA): endometriosis or ovarian malignancy? A case report. International journal of reproductive biomedicine, 16 (6), 413–416.
  • Kitajima, M., et al., 2018. Association between ovarian endometrioma and ovarian reserve. Frontiers in bioscience, 10, 92–102.
  • Kurdoglu, Z., et al., 2009. Comparison of the clinical value of CA 19-9 versus CA 125 for the diagnosis of endometriosis. Fertility and sterility, 92 (5), 1761–1763.
  • Mao, A.J., and Anastasi, J.K., 2010. Diagnosis and management of endometriosis: the role of the advanced practice nurse in primary care. Journal of the American academy of nurse practitioners, 22 (2), 109–116.
  • Murta, E.F.C., et al., 2004. Ultrasonographic criteria and tumor marker assay are good procedures for the diagnosis of ovarian neoplasia in preselected outpatients. European journal of gynaecological oncology, 25, 707–712.
  • Murta, E.F., and Nomelini, R.S., 2006. Early diagnosis and predictors of malignancy of adnexal masses. Current opinion in obstetrics & gynecology, 18 (1), 14–19.
  • Nakagawa, N., et al., 2015. Reactivity of CA19-9 and CA125 in histological subtypes of epithelial ovarian tumors and ovarian endometriosis. Acta medica okayama, 69 (4), 227–235.
  • Nisenblat, V., et al., 2016. Blood biomarkers for the non-invasive diagnosis of endometriosis. Cochrane database systematic reviews, 2016 (5), CD012179.
  • Takada, A., et al., 1993. Contribution of carbohydrate antigens sialyl Lewis A and sialyl Lewis X to adhesion of human cancer cells to vascular endothelium. Cancer research, 53 (2), 354–361.
  • Winter, W.E. III, et al., 2007. Prognostic factors for stage III epithelial ovarian cancer: a Gynecologic Oncology Group Study. Journal of clinical oncology, 25 (24), 3621–3627.
  • Yilmazer, M., et al., 2003. Unusually elevated serum carbohydrate antigen 125 (CA125) and CA19-9 levels as a result of unruptured bilateral endometrioma. The Australian & New Zealand journal of obstetrics & gynaecology, 43 (4), 329–330.
  • Zhu, H., et al., 2016. Serum carcinogenic antigen (CA)-125 and CA 19-9 combining pain score in the diagnosis of pelvic endometriosis in infertile women. Clinical and Experimental Obstetrics & Gynecology, 43 (6), 826–829.

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