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Gestational diabetes mellitus and inflammatory biomarkers of neutrophil-lymphocyte ratio and platelet-lymphocyte ratio: a systematic review and meta-analysis

ORCID Icon, , , , ORCID Icon &
Pages 491-498 | Received 04 Feb 2021, Accepted 30 Apr 2021, Published online: 28 Jun 2021

References

  • Aktulay, A., et al., 2015. Gestational diabetes mellitus seems to be associated with inflammation. Acta clinica croatica, 54 (4), 475–478.
  • Angkananard, T., et al., 2018. Neutrophil lymphocyte ratio and cardiovascular disease risk: a systematic review and meta-analysis. BioMed research international, 2018, 1–11.
  • Basu, J., et al., 2020. Gestational diabetes mellitus in a tertiary care hospital of Kolkata, India: prevalence, pathogenesis and potential disease biomarkers. Experimental and clinical endocrinology & diabetes, 128 (04), 216–223.
  • Buchanan, T.A., 2001. Pancreatic B-cell defects in gestational diabetes: implications for the pathogenesis and prevention of type 2 diabetes. The journal of clinical endocrinology & metabolism, 86 (3), 989–993.
  • Caglayan, E.K., et al., 2016. Is there any relationship between serum sirtuin-1 level and neutrophil-lymphocyte ratio in hyperemesis gravidarum? Journal of perinatal medicine, 44 (3), 315–320.
  • Cakmak, B.D., et al., 2019. Assessment of relationship between serum vascular adhesion protein-1 (VAP-1) and gestational diabetes mellitus. Biomarkers, 24 (8), 750–756.
  • Farrar, D., et al., 2016. Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis. BMJ, 354, i4694.
  • Fashami, M.A., et al., 2020. Is there an association between platelet and blood inflammatory indices and the risk of gestational diabetes mellitus? Obstetrics & gynecology science, 63 (2), 133–140.
  • Garcia-Vargas, L., et al., 2012. Gestational diabetes and the offspring: implications in the development of the cardiorenal metabolic syndrome in offspring. Cardiorenal medicine, 2 (2), 134–142.
  • Kalay, N., et al., 2012. Hematologic parameters and angiographic progression of coronary atherosclerosis. Angiology, 63 (3), 213–217.
  • Kang, Q., et al., 2020. Predictive role of neutrophil-to-lymphocyte ratio in preeclampsia: a meta-analysis including 3982 patients. Pregnancy hypertension, 20, 111–118.
  • Kim, S.Y., Sharma, A.J., and Callaghan, W.M., 2012. Gestational diabetes and childhood obesity: what is the link? Current opinion in obstetrics & gynecology, 24 (6), 376–381.
  • Kirbas, A., Daglar, K., and Danisman, N., 2016. Evaluation of inflammatory related markers in gestational diabetes mellitus. Journal of clinical and analytical medicine, 7 (4), 501–504.
  • Kirbas, A., et al., 2014. Neutrophil-to-lymphocyte ratio as a diagnostic marker of intrahepatic cholestasis of pregnancy. European journal of obstetrics & gynecology and reproductive biology, 180, 12–15.
  • Madan, J.C., et al., 2009. Maternal obesity and markers of inflammation in pregnancy. Cytokine, 47 (1), 61–64.
  • Mannaerts, D., et al., 2019. Are neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and/or mean platelet volume (MPV) clinically useful as predictive parameters for preeclampsia? The journal of maternal-fetal & neonatal medicine, 32 (9), 1412–1419.
  • Mertoğlu, C., et al., 2019. A study of inflammatory markers in gestational diabetes mellitus. Gynecology obstetrics & reproductive medicine, 25 (1), 7–11.
  • Ozler, S., et al., 2019. The value of total antioxidant status and serum tumor necrosis factor-α levels at 24–28 weeks of gestation in the prediction of optimal treatment protocol in gestational diabetes mellitus. Experimental and clinical endocrinology & diabetes, 127 (07), 485–491.
  • Sahbaz, A., et al., 2016. Comparison of the predictive value of plateletcrit with various other blood parameters in gestational diabetes development. Journal of obstetrics and gynaecology, 36 (5), 589–593.
  • Şahin Uysal, N., et al., 2020. Is the serum delta neutrophil index level different in gestational diabetic women? Journal of maternal-fetal and neonatal medicine, 33, 3349–3354.
  • Sargin, M.A., et al., 2016. Neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios: are they useful for predicting gestational diabetes mellitus during pregnancy? Therapeutics and clinical risk management, 12, 657–665.
  • Seshiah, V., et al., 2006. Gestational diabetes mellitus-guidelines. JAPI, 54, 622.
  • Soydinc, S., et al., 2013. Blood pressure diurnal rhythm is related with hematological indices in gestational diabetes mellitus patients. Acta medica mediterranea, 29 (4), 767–773.
  • Sun, T., et al., 2019. Elevated first-trimester neutrophil count is associated with the development of gestational diabetes mellitus in pregnant women. Diabetes, 68 (Supplement 1), 86-LB.
  • Teh, W.T., et al., 2011. Risk factors for gestational diabetes mellitus: implications for the application of screening guidelines. Australian and New Zealand journal of obstetrics and gynaecology, 51 (1), 26–30.
  • Vokalova, L., et al., 2018. Excessive neutrophil activity in gestational diabetes mellitus: could it contribute to the development of preeclampsia? Front endocrinol (Lausanne), 9, 542.
  • Wang, J., et al., 2020. Clinical significance of neutrophil–lymphocyte ratio and monocyte–lymphocyte ratio in women with hyperglycemia. Postgraduate medicine, 132 (8), 702–707.
  • Yıldız, S., et al., 2016. Which hemogram parameter is more cautionary in euthyroid patients with gestational diabetes mellitus. Eastern journal of medicine, 21 (4), 162–167.
  • Yilmaz, H., et al., 2014. Benefits of the neutrophil-to-lymphocyte ratio for the prediction of gestational diabetes mellitus in pregnant women. Experimental and clinical endocrinology & diabetes, 122 (01), 39–43.
  • Yılmaz, Z.V., et al., 2017. Association of complete blood count parameters with gestational diabetes mellitus. Gynecology obstetrics & reproductive medicine, 23 (2), 65–69.
  • Zang, S., et al., 2015. Neutrophils play a crucial role in the early stage of nonalcoholic steatohepatitis via neutrophil elastase in mice. Cell biochemistry and biophysics, 73 (2), 479–487.

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