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Original Articles

Characterization of the association between cigarette smoking intensity and urinary concentrations of 2-hydroxyethyl mercapturic acid among exclusive cigarette smokers in the National Health and Nutrition Examination Survey (NHANES) 2011–2016

ORCID Icon, , , , ORCID Icon, & ORCID Icon show all
Pages 656-664 | Received 24 May 2021, Accepted 15 Aug 2021, Published online: 02 Sep 2021

References

  • Alwis, K.U., et al., 2012. Simultaneous analysis of 28 urinary VOC metabolites using ultra high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry (UPLC-ESI/MSMS). Analytica chimica acta, 750, 152–160.
  • ASTDR. 2020. Toxicological profile for ethylene oxide. ATSDR’s Toxicological Profiles.
  • Bader, M., Lewalter, J., and Angerer, J., 1995. Analysis of N-alkylated amino acids in human hemoglobin: evidence for elevated N-methylvaline levels in smokers. International archives of occupational and environmental health, 67 (4), 237–242.
  • Bagchi, P., et al., 2018. Crotonaldehyde exposure in U.S. tobacco smokers and nonsmokers: NHANES 2005–2006 and 2011–2012. Environmental research, 163, 1–9.
  • Barr, D.B., et al., 2005. Urinary creatinine concentrations in the U.S. population: implications for urinary biologic monitoring measurements. Environmental health perspectives, 113 (2), 192–200.
  • Benowitz, N.L., et al., 2009. Optimal serum cotinine levels for distinguishing cigarette smokers and nonsmokers within different racial/ethnic groups in the United States between 1999 and 2004. American journal of epidemiology, 169 (2), 236–248.
  • Bergmark, E., 1997. Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers. Chemical research in toxicology, 10 (1), 78–84.
  • Biren, C., et al., 2020. Isoprene exposure in the United States based on urinary IPM3: NHANES 2015–2016. Environmental science & technology, 54 (4), 2370–2378.
  • Bono, R., et al., 1999. Formation of N-(2-hydroxyethyl)valine due to exposure to ethylene oxide via tobacco smoke: a risk factor for onset of cancer. Environmental research, 81 (1), 62–71.
  • Bono, R., et al., 2005. Cotinine and N-(2-hydroxyethyl)valine as markers of passive exposure to tobacco smoke in children. Journal of exposure analysis and environmental epidemiology, 15 (1), 66–73.
  • Brandt-Rauf, P.W., et al., 2012. Plastics and carcinogenesis: the example of vinyl chloride. Journal of carcinogenesis, 11, 5.
  • Calafat, A.M., et al., 1999. Reference range concentrations of N-acetyl-S-(2-hydroxyethyl)-L-cysteine, a common metabolite of several volatile organic compounds, in the urine of adults in the United States. Journal of exposure analysis and environmental epidemiology, 9 (4), 336–342.
  • Capella, K.M., et al., 2019. Ethylbenzene and styrene exposure in the United States based on urinary mandelic acid and phenylglyoxylic acid: NHANES 2005–2006 and 2011–2012. Environmental research, 171, 101–110.
  • Carmella, S.G., et al., 2009. Effects of smoking cessation on eight urinary tobacco carcinogen and toxicant biomarkers. Chemical research in toxicology, 22 (4), 734–741.
  • Caudill, S.P., Schleicher, R.L., and Pirkle, J.L., 2008. Multi-rule quality control for the age-related eye disease study. Statistics in medicine, 27 (20), 4094–4106.
  • Chen, M., et al., 2019. Longitudinal stability in cigarette smokers of urinary biomarkers of exposure to the toxicants acrylonitrile and acrolein. PLoS one, 14 (1), e0210104–13.
  • Cole, P., Mandel, J.S., and Collins, J.J., 2008. Acrylonitrile and cancer: a review of the epidemiology. Regulatory toxicology and pharmacology: RTP, 52 (3), 342–351.
  • Cone, E.J., et al., 2009. Normalization of urinary drug concentrations with specific gravity and creatinine. Journal of analytical toxicology, 33 (1), 1–7.
  • Darrall, K.G., et al., 1998. Determination of benzene and associated volatile compounds in mainstream cigarette smoke. The analyst, 123 (5), 1095–1101.
  • De Jesús, V.R., 2012. Laboratory procedure manual: Volatile Organic Compounds (VOCs) metabolites [online]. The National Center for Health Statistics. Available from: https://wwwn.cdc.gov/nchs/data/nhanes/2013-2014/labmethods/UVOC_H_MET.pdf [Accessed 20 Jul 2021].
  • De Jesús, V.R., et al., 2020. Urinary biomarkers of exposure to volatile organic compounds from the population assessment of tobacco and health study wave 1 (2013–2014). International journal of environmental research and public health, 17 (15), 1–12.
  • De Jesús, V.R., et al., 2021. Characterization of acrylonitrile exposure in the United States based on urinary n-acetyl-S-(2-cyanoethyl)-l-cysteine (2CYEMA): NHANES 2011-2016. Journal of exposure science & environmental epidemiology, 31 (2), 377–385.
  • Fennell, T.R., et al., 2000. Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione s-transferase T1-null and M1-null genotypes. Cancer epidemiology biomarkers and prevention, 9 (7), 705–712.
  • Filser, J.G., et al., 1993. Pharmacokinetics of ethylene in man; body burden with ethylene oxide and hydroxyethylation of hemoglobin due to endogenous and environmental ethylene. Archives of toxicology, 67 (3), 230–230.
  • Hoffmann, D., Hoffmann, I., and El-Bayoumy, K., 2001. The less harmful cigarette: a controversial issue. A tribute to Ernst L. Wynder. Chemical research in toxicology, 14 (7), 767–790.
  • Hornung, R.W., and Reed, L.D., 1990. Estimation of average concentration in the presence of nondetectable values. Applied occupational and environmental hygiene, 5 (1), 46–51.
  • Jain, R.B., and Bernert, J.T., 2010. Effect of body mass index and total blood volume on serum cotinine levels among cigarette smokers: NHANES 1999-2008. Clinica chimica acta, 411 (15–16), 1063–1068.
  • Jain, R.B., 2014. Trends in serum cotinine concentrations among daily cigarette smokers: data from NHANES 1999-2010. The science of the total environment, 472, 72–77.
  • Jain, R.B., 2015. Distributions of selected urinary metabolites of volatile organic compounds by age, gender, race/ethnicity, and smoking status in a representative sample of U.S. adults. Environmental toxicology and pharmacology, 40 (2), 471–479.
  • Jinot, J., et al., 2018. Carcinogenicity of ethylene oxide: key findings and scientific issues. Toxicology mechanisms and methods, 28 (5), 386–396.
  • Kautiainen, A., and Törnqvist, M., 1991. Monitoring exposure to simple epoxides and alkenes through gas chromatographic determination of hemoglobin adducts. International archives of occupational and environmental health, 63 (1), 27–31.
  • Kenwood, B.M., et al., 2021. Characterization of US population levels of urinary methylcarbamoyl mercapturic acid, a metabolite of N,N-dimethylformamide and methyl isocyanate, in the National Health and Nutrition Examination Survey (NHANES) 2005–2006 and 2011–2016. Environmental science and pollution research, 28 (13), 16781–16791.
  • Kirman, C.R., et al., 2005. Cancer dose-response assessment for acrylonitrile based upon rodent brain tumor incidence: use of epidemiologic, mechanistic, and pharmacokinetic support for nonlinearity. Regulatory toxicology and pharmacology: RTP, 43 (1), 85–103.
  • Kirman, C.R., et al., 2021. Ethylene oxide review: characterization of total exposure via endogenous and exogenous pathways and their implications to risk assessment and risk management. Journal of toxicology and environmental health. Part B, critical reviews, 24 (1), 1–29.
  • Luo, X., et al., 2020. Urinary cyanoethyl mercapturic acid, a biomarker of the smoke toxicant acrylonitrile, clearly distinguishes smokers from nonsmokers. Nicotine & tobacco research, 22 (10), 1744–1747.
  • Mendes, G.C.C., Brandão, T.R.S., and Silva, C.L.M., 2007. Ethylene oxide sterilization of medical devices: a review. American journal of infection control, 35 (9), 574–581.
  • Müller, M., et al., 1998. Ethylene oxide-protein adduct formation in humans: influence of glutathione-S-transferase polymorphisms. International archives of occupational and environmental health, 71 (7), 499–502.
  • National Center for Health Statistics. 2021a. National Health and Nutrition Examination Survey [online]. The National Center for Health Statistics. Available from: https://www.cdc.gov/nchs/nhanes/index.htm.
  • National Center for Health Statistics. 2021b. NHANES questionnaires, datasets, and related documentation [online]. Available from: https://wwwn.cdc.gov/nchs/nhanes/search/default.aspx.
  • NCHS Research Ethics Review Board (ERB) Approval. 2017. National Center for Health Statistics, Centers for Disease Control and Prevention. Available from: https://www.cdc.gov/nchs/nhanes/irba98.htm#:∼:text=NCHSResearchEthicsReviewBoard%28ERB%29Approval%2A%2A,2017Contentsource%3A [Accessed 10 Jul 2020].
  • Nieto, A., et al., 2021. Exposure to 1,3-butadiene in the U.S. population: National Health and Nutrition Examination Survey 2011–2016. Biomarkers: biochemical indicators of exposure, response, and susceptibility to chemicals, 26 (4), 371–383.
  • Olaguer, E.P., et al., 2020. Ethylene oxide exposure attribution and emissions quantification based on ambient air measurements near a sterilization facility. International journal of environmental research and public health, 17 (1), 42.
  • Parker, J.D., et al., 2018. Vital and health statistics national center for health statistics data presentation standards for proportions. The national center for health statistics, 2 (175), 1–14.
  • Pazo, D.Y., et al., 2016. Mainstream smoke levels of volatile organic compounds in 50 U.S. domestic cigarette brands smoked with the ISO and Canadian intense protocols. Nicotine & tobacco research, 18 (9), 1886–1894.
  • Pirkle, J.L., et al., 1996. Exposure of the US population to environmental tobacco smoke: the third national health and nutrition examination survey, 1988 to 1991. JAMA, 275 (16), 1233–1240.
  • Pluym, N., et al., 2015. Analysis of 18 urinary mercapturic acids by two high-throughput multiplex-LC-MS/MS methods. Analytical and bioanalytical chemistry, 407 (18), 5463–5476.
  • Scherer, G., et al., 2007. Relationship between machine-derived smoke yields and biomarkers in cigarette smokers in Germany. Regulatory toxicology and pharmacology, 47 (2), 171–183.
  • Schettgen, T., et al., 2002. Hemoglobin adducts of ethylene oxide, propylene oxide, acrylonitrile and acrylamide-biomarkers in occupational and environmental medicine. Toxicology letters, 134 (1–3), 65–70.
  • Szwiec, E., Friedman, L., and Buchanan, S., 2020. Levels of ethylene oxide biomarker in an exposed residential community. International journal of environmental research and public health, 17 (22), 8646–8647.
  • Tates, A.D., et al., 1991. Biological and chemical monitoring of occupational exposure to ethylene oxide. Mutation research, 250 (1–2), 483–497.
  • Tavares, R., et al., 1996. Monitoring of exposure to acrylonitrile by determination of N-(2-cyanoethyl)valine at the N-terminal position of haemoglobin. Carcinogenesis, 17 (12), 2655–2660.
  • Tavares, R., et al., 1994. Transplacental exposure to genotoxins. Evaluation in haemoglobin of hydroxyethylvaline adduct levels in smoking and non-smoking mothers and their newborns. Carcinogenesis, 15 (6), 1271–1274.
  • Todd, G. D., et al., 2006. Toxicological profile for vinyl chloride. Agency for Toxic Substances and Disease Registry. Available from: https://wwwn.cdc.gov/TSP/ToxProfiles/ToxProfiles.aspx?id=282&tid=51.
  • Törnqvist, M., et al., 1986. Tissue doses of ethylene oxide in cigarette smokers determined from adduct levels in hemoglobin. Carcinogenesis, 7 (9), 1519–1521.
  • US Department of Agriculture. 2019. Food and Nutrient Database for Dietary Studies (FNDDS) [online]. Food Surveys Research Group, Beltsville Human Nutrition Research Center. Available from: https://data.nal.usda.gov/dataset/food-and-nutrient-database-dietary-studies-fndds.
  • Vermeulen, N.P.E., et al., 1989. N-acetyl-S-(2-hydroxyethyl)-L-cysteine as a potential tool in biological monitoring studies? A critical evaluation of possibilities and limitations Archives of toxicology, 63 (3), 173–184.
  • Von Stedingk, H., et al., 2011. Analysis of hemoglobin adducts from acrylamide, glycidamide, and ethylene oxide in paired mother/cord blood samples from Denmark. Chemical research in toxicology, 24 (11), 1957–1965.
  • Yang, M., et al., 2018. High-throughput, simultaneous quantitation of hemoglobin adducts of acrylamide, glycidamide, and ethylene oxide using UHPLC-MS/MS ⋆. Journal of chromatography. B, analytical technologies in the biomedical and life sciences, 1086, 197–205.
  • Zhang, X., et al., 2014. Simultaneous determination of five mercapturic acid derived from volatile organic compounds in human urine by LC-MS/MS and its application to relationship study. Journal of chromatography b, 967, 102–109.

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