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Research Article

Higher expression of SALL4-A isoform is correlated with worse outcomes and progression of the disease in subtype of testicular germ cell tumours

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Pages 324-339 | Received 01 Mar 2024, Accepted 25 May 2024, Published online: 05 Jun 2024

References

  • Al-Mousa A, Shashaa MN, Alkarrash MS, Alkhamis M, Ghabreau L, Dandal M. 2020. Unusual case of classic testicular seminoma in a 90-year-old patient: a case report. J Med Case Rep. 14:182.
  • Almstrup K, Lobo J, Mørup N, Belge G, Rajpert-De Meyts E, Looijenga LHJ, Dieckmann K-P. 2020. Application of mirnas in the diagnosis and monitoring of testicular germ cell tumours. Nat Rev Urol. 17(4):201–213. doi: 10.1038/s41585-020-0296-x
  • Álvarez C, Quiroz A, Benítez-Riquelme D, Riffo E, Castro AF, Pincheira R. 2021. Sall proteins; common and antagonistic roles in cancer. Cancers (Basel). 13(24):6292. doi: 10.3390/cancers13246292
  • Bahrami A, Ro JY, Ayala AG. 2007. An overview of testicular germ cell tumours. Arch Pathol Lab Med. 131(8):1267–1280. doi: 10.5858/2007-131-1267-AOOTGC
  • Cao D, Guo S, Allan RW, Molberg KH, Peng Y. 2009. Sall4 Is a novel sensitive and specific marker of ovarian primitive germ cell tumours and is particularly useful in distinguishing yolk sac tumour from clear cell carcinoma. Am J Surg Pathol. 33(6):894–904. doi: 10.1097/PAS.0b013e318198177d
  • Cao D, Humphrey PA, Allan RW. 2009. Sall4 is a novel sensitive and specific marker for metastatic germ cell tumours, with particular utility in detection of metastatic yolk sac tumours. Cancer. 115(12):2640–2651. doi: 10.1002/cncr.24308
  • Cao D, Li J, Guo CC, Allan RW, Humphrey PA. 2009. Sall4 is a novel diagnostic marker for testicular germ cell tumours. Am J Surg Pathol. 33(7):1065–1077. doi: 10.1097/PAS.0b013e3181a13eef
  • Forghanifard MM, Moghbeli M, Raeisossadati R, Tavassoli A, Mallak AJ, Boroumand-Noughabi S, Abbaszadegan MR. 2013. Role of Sall4 in the progression and metastasis of colorectal cancer. J Biomed Sci. 20(1):6. doi: 10.1186/1423-0127-20-6
  • Gautam AK, Wang C, Zeng J, Wang J, Lu J, Wei J, Huang G, Mo B, Luo M, Mo B. 2015. Expression and clinical significance of Sall4 and Lgr5 in patients with lung cancer. Oncol Lett. 10(6):3629–3634. doi: 10.3892/ol.2015.3772
  • Ghods R, Ghahremani MH, Madjd Z, Asgari M, Abolhasani M, Tavasoli S, Mahmoudi AR, Darzi M, Pasalar P, Jeddi-Tehrani M, et al. 2014. High placenta-specific 1/low prostate-specific antigen expression pattern in high-grade prostate adenocarcinoma. Cancer Immunol Immunother. 63(12):1319–1327. doi: 10.1007/s00262-014-1594-z
  • Hanna NH, Einhorn LH. 2014. Testicular cancer–discoveries and updates. N Engl J Med. 371(21):2005–2016. doi: 10.1056/NEJMra1407550
  • Jourdan F, Sebbagh N, Comperat E, Mourra N, Flahault A, Olschwang S, Duval A, Hamelin R, Flejou JF. 2003. Tissue microarray technology: validation in colorectal carcinoma and analysis of P53, Hmlh1, and Hmsh2 immunohistochemical expression. Virchows Arch. 443(2):115–121. doi: 10.1007/s00428-003-0833-z
  • Kalantari E, Razmi M, Tajik F, Asadi-Lari M, Ghods R, Madjd Z. 2022. Oncogenic functions and clinical significances of Dclk1 isoforms in colorectal cancer: a systematic review and meta-analysis. Cancer Cell Int. 22(1):217. doi: 10.1186/s12935-022-02632-9
  • Kollmannsberger C, Kuzcyk M, Mayer F, Hartmann JT, Kanz L, Bokemeyer C. 1999. Late toxicity following curative treatment of testicular cancer. Semin Surg Oncol. 17:275–281.
  • Lakpour N, Ghods R, Sadeghi MR, Ranjbar MM, Abolhasani M, Kiani J, Saliminejad K, Balay-Goli L, Bayat AA, Souri F, et al. 2022. Production and characterization of a new specific monoclonal antibody against a-isoform of Sall4: a novel emerging testicular cancer marker. Andrologia. 54(11):e14608. doi: 10.1111/and.14608
  • Lakpour N, Saliminejad K, Ghods R, Reza Sadeghi M, Pilatz A, Khosravi F, Madjd Z. 2021. Potential biomarkers for testicular germ cell tumour: risk assessment, diagnostic, prognostic and monitoring of recurrence. Andrologia. 53(4):e13998. doi: 10.1111/and.13998
  • Langer R, Von Rahden BH, Nahrig J, Von Weyhern C, Reiter R, Feith M, Stein HJ, Siewert JR, Hofler H, Sarbia M. 2006. Prognostic significance of expression patterns of C-Erbb-2, P53, P16ink4a, P27kip1, cyclin D1 and epidermal growth factor receptor in oesophageal adenocarcinoma: a tissue microarray study. J Clin Pathol. 59:631–634.
  • Leao R, Ahmad AE, Hamilton RJ. 2019. Testicular cancer biomarkers: a role for precision medicine in testicular cancer. Clin Genitourin Cancer. 17:e176–e83.
  • Liu A, Cheng L, Du J, Peng Y, Allan RW, Wei L, Li J, Cao D. 2010. Diagnostic utility of novel stem cell markers Sall4, Oct4, Nanog, Sox2, Utf1, and Tcl1 in primary mediastinal germ cell tumours. Am J Surg Pathol. 34(5):697–706. doi: 10.1097/PAS.0b013e3181db84aa
  • Liu J, Sauer MA, Hussein SG, Yang J, Tenen DG, Chai L. 2021. Sall4 and microrna: the role of Let-7. Genes (Basel). 12(9):1301. doi: 10.3390/genes12091301
  • Liu C, Yao F, Mao X, Li W, Chen H. 2020. Effect of Sall4 on the proliferation, invasion and apoptosis of breast cancer cells. Technol Cancer Res Treat. 19:1533033820980074. doi: 10.1177/1533033820980074
  • Lobo J, Acosta AM, Netto GJ. 2023. Molecular biomarkers with potential clinical application in testicular cancer. Mod Pathol. 36:100307.
  • Magers MJ, Idrees MT. 2018. Updates in staging and reporting of testicular cancer. Surg Pathol Clin. 11:813–824.
  • Miettinen M, Wang Z, McCue PA, Sarlomo-Rikala M, Rys J, Biernat W, Lasota J, Lee YS. 2014. Sall4 expression in germ cell and non-germ cell tumours: a systematic immunohistochemical study of 3215 cases. Am J Surg Pathol. 38(3):410–420. doi: 10.1097/PAS.0000000000000116
  • Sarma RJ, Subbarayan S, Zohmingthanga J, Chenkual S, Zomuana T, Lalruatfela ST, Pautu JL, Maitra A, Kumar NS. 2022. Transcriptome analysis reveals Sall4 as a prognostic key gene in gastric adenocarcinoma. J Egypt Natl Canc Inst. 34(1):11. doi: 10.1186/s43046-022-00108-5
  • Schrader M, Burger AM, Müller M, Krause H, Straub B, Schostak M, Schulze W, Lauke H, Miller K. 2002. The differentiation status of primary gonadal germ cell tumours correlates inversely with telomerase activity and the expression level of the gene encoding the catalytic subunit of telomerase. BMC Cancer. 2(1):32. doi: 10.1186/1471-2407-2-32
  • Shahin M, Saeednejad Zanjani L, Abolhasani M, Rahbar M, Asgari M, Madjd Z. 2020. Low level expression of human telomerase reverse transcriptase predicts cancer-related death and progression in embryonal carcinoma. J Cancer Res Clin Oncol. 146(11):2753–2775. doi: 10.1007/s00432-020-03319-2
  • Shanmugalingam T, Soultati A, Chowdhury S, Rudman S, Van Hemelrijck M. 2013. Global incidence and outcome of testicular cancer. Clin Epidemiol. 5:417–427.
  • Siegel RL, Miller KD, Jemal A. 2018. Cancer statistics, 2018. CA Cancer J Clin. 68:7–30.
  • Siegel RL, Miller KD, Jemal A. 2019. Cancer statistics, 2019. CA Cancer J Clin. 69:7–34.
  • Szymonik J, Wala K, Gornicki T, Saczko J, Pencakowski B, Kulbacka J. 2021. The impact of iron chelators on the biology of cancer stem cells. Int J Mol Sci. 23(1):89.
  • Tatetsu H, Kong NR, Chong G, Amabile G, Tenen DG, Chai L. 2016. Sall4, the missing link between stem cells, development and cancer. Gene. 584(2):111–119. doi: 10.1016/j.gene.2016.02.019
  • Urbini M, Bleve S, Schepisi G, Menna C, Gurioli G, Gianni C, Giorgi UD. 2023. Biomarkers for salvage therapy in testicular germ cell tumours. Int J Mol Sci. 24(23):16872.
  • Wang F, Liu A, Peng Y, Rakheja D, Wei L, Xue D, Allan RW, Molberg KH, Li J, Cao D. 2009. Diagnostic utility of Sall4 in extragonadal yolk sac tumours: an immunohistochemical study of 59 cases with comparison to placental-like alkaline phosphatase, alpha-fetoprotein, and glypican-3. Am J Surg Pathol. 33(10):1529–1539. doi: 10.1097/PAS.0b013e3181ad25d5
  • Wang B, Xie Y, Zheng L, Zheng X, Gao J, Liu X, Yuan Y, Li Z, Lu N, Xue L. 2021. Both the serum AFP test and AFP/GPC3/SALL4 immunohistochemistry are beneficial for predicting the prognosis of gastric adenocarcinoma. BMC Gastroenterol. 21(1):408. doi: 10.1186/s12876-021-01986-0
  • Wu P, Luo R, Sun B, Zhao J, Xu Q, Feng S, Chen X, Wang C. 2020. Sall4 is a useful marker for pediatric yolk sac tumours. Pediatr Surg Int. 36(6):727–734. doi: 10.1007/s00383-020-04652-w
  • Yang Y, Wang X, Liu Y, Hu Y, Li Z, Li Z, Bu Z, Wu X, Zhang L, Ji J. 2021. Up-regulation of Sall4 is associated with survival and progression via putative WNT pathway in gastric cancer. Front Cell Dev Biol. 9:600344. doi: 10.3389/fcell.2021.600344
  • Yue X, Xiao L, Yang Y, Liu W, Zhang K, Shi G, Zhou H, Geng J, Ning X, Wu J, et al. 2015. High cytoplasmic expression of Sall4 Predicts a malignant phenotype and poor prognosis of breast invasive ductal carcinoma. Neo. 62(06):980–988. doi: 10.4149/neo_2015_119
  • Zhu F, Liu Z, Zhou Q, Fan J, Zhou D, Xing L, Bo H, Tang L, Fan L. 2021. Identification of MRNA prognostic markers for TGCT by integration of co-expression and Cerna network. Front Endocrinol (Lausanne). 12:743155. doi: 10.3389/fendo.2021.743155

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