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Research Article

Interactions between HIV-1 gp120, chemokines, and cultured adult microglial cells

Pages 196-207 | Published online: 10 Jul 2009

References

  • Albright AV, Shieh JTC, Itoh T, Lee B, Pleasure D, O'Connor MJ, Doms RW, Gonzalez-Scarano F (1999). Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for HIV-1 dementia isolates. I Virol 73: 205–213.
  • Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA (1996). CC CKR5: a RANTES, MIP-la, MIP-1,6 receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955–1958.
  • Arthos J, Rubbert A, Rabin RL, Cicala C, Machado E, Wildt K, Hanbach M, Steenbeke TD, Swofford R, Farber JM, Fauci AS (2000). CCR5 signal transduction in macrophages by human immunodeficiency virus and simian immunodeficiency virus envelopes. I Virol 74: 6418–6424.
  • Bacon KB, Harrison JK (2000). Chemokines and their re-ceptors in neurobiology: perspectives in physiology and homeostasis. I Neuroimmunol 104: 2–7.
  • Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik ASTJ (1997). A new class of membrane-bound chemokine with a CX3C motif. Nature 385: 640–644.
  • Bo L, Dawson TM, Wesselingh S, Mork S, Choi S, Kong PA, Hanley D, Trapp BD (1994). Induction of nitric oxide synthase in demylinating regions of multiple sclerosis brains. Ann Neurol 36: 778–786.
  • Boddeke EW, Meigel I, Frentzel S, Biber K, Renn LQ, Gebicke-Harter P (1999). Functional expression of the fractalkine (CX3C) receptor and its regulation by lipopolysaccharide in rat microglia. Eur I Pharmacol 372: 309–313.
  • Boshoff C, Endo Y, Collins PD, Takeuchi Y, Reeves JD, Schweickart VL, Siani MA, Sasaki T, Williams TJ, Gray PW, Moore PS, Chang Y, Weiss RA (1997). Angio-genic and HIV-inhibitory functions of KSHV-encoded chemokines. Science 278: 290–294.
  • Budka H (1990). Human immunodeficiency virus (HIV) en-velope and core proteins in CNS tissues of patients with the aquired immune deficiency syndrome (AIDS). Acta Neuropathol (Berl) 79: 611–619.
  • Campbell JJ, Butcher EC (2000). Chemokines in tissue-specific and microenvironment-specific lymphocyte homing. Curr Opin Immunol 12: 336–341.
  • Capobianchi MR, Ankel H, Ameglio F, Paganelli R, Pizzoli PM, Dianzani F (1992). Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer. AIDS Res Hum Retroviruses 8: 575–579.
  • Choe H, Farzan M, Sun Y, Sullivan N, Rollins B, Ponath PD, Wu J, Mackay CR, LaRosa G, Newman W, Gerard N, Gerard C, Sodroski J (1996). The fi-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 85: 1135–1148.
  • Collman R, Hassan NF, Walker R, Godfrey B, Cutilli J, Hastings J, Freidman H, Douglas SD, Nathanson N (1989). Infection of monocyte-derived macrophages with human immunodeficiency virus type 1 (HIV-1). I Exp Med 170: 1149–1163.
  • Davis CB, Dikic I, Unutm az D, Hill CM, Arthos J, Siani MA, Thompson DA, SchlessingerJ, Littm an DR (1997). Signal transduction due to HIV-1 envelope interactions with chemokine receptors CXCR4 or CCR5. I Exp Med 186: 1793–1798.
  • Deng H, Liu R, Ellmeier W, Choe S, Unutmaz D, Burkhart M, Di Marzio P, Marmon S, Sutton RE, Hill CM, Davis CB, Peiper SC, Schall TJ, Littman DR, Landau NR (1996). Identification of a major co-receptor for primary isolates of HIV-1. Nature 381: 661–666.
  • Dick AD, Pell M, Brew BJ, Foulcher E, Sedgwick JD (1997). Direct ex vivo flow cytometric analysis of human mi-croglial cell CD4 expression: examination of central ner-vous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease. AIDS 11: 1699–1708.
  • Doranz BJ, Baik SS, Doms RW (1999). Use of a gp120 bind-ing assay to dissect the requirements and kinetics of hu-man immunodeficiency virus fusion events. I Virol 73: 10346–10358.
  • Doranz BJ, Rucker J, Yi Y, Smyth RJ, Samson M, Peiper SC, Parmentier M, Collman RG, Doms RW (1996). A dual-tropic primary HIV-1 isolate that uses fusin and the fi-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 85: 1149–1158.
  • Dreyer EB, Kaiser PK, Offermann JT, Lipton SA (1990). HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science 248: 364–367.
  • Earl PL, Moss B, Doms RW (1991). Folding, interactionwith GRP78-BiP, assembly, and transport of the human im-munodeficiency virus type 1 envelope protein. I Virol 65: 2047–2055.
  • Feng Y, Broder CC, Kennedy PE, Berger EA (1996). HIV-1 entry cofactor:functional cDNA cloning of a seven-transmembrane, G protein-coupled receptor. Science 272: 872–877.
  • Gabuzda DH, Ho DD, de la Monte SM, Hirsch MS, Rota TR, Sobel, RA (1986). Immunohistochemical identification of HTLV-III antigen in brains of patients with AIDS. Ann Neurol 20: 289–295.
  • Gartner S, Markovits P, Markovitz DM, Betts RF, Popovic M (1986). Virus isolation from and identification of HTLV-III/LAV-producing cells in brain tissue from a patient with AIDS. JAMA 256: 2365–2371.
  • Glabinski AR, Ransohoff RM (1999). Chemokines and chemokine receptors in CNS pathology. I Neurovirol 5: 3–12.
  • Glass JD, Fedor H, Wesselingh SL, McArthur JC (1995). Im-munocytochemic al quantitation of human immunode-ficiency virus in the brain: correlations with dementia. Ann Neurol 38: 755–762.
  • Glass JD, Wesselingh SL, Selnes OA, McArthur JC (1993). Clinical-neuropathological correlation in HIV-associated dementia. Neurol 43: 2230–2237.
  • Gu R, Westervelt P, Ratner L (1993). Role of HIV-1 enve-lope V3 loop cleavage in cell tropism. AIDS Res Hum Retroviruses 9: 1007–1015.
  • Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK, Streit WJ, Salafranca MN, Adhikari S, Thompson DA, Botti P, Bacon KB, Feng L (1998). Role for neuronally derived fractalkine in mediating inter-actions between neurons and CX3CR1-expressing mi-croglia. Proc Natl Acad Sci USA 95: 10896–10901.
  • Hegg CC, Hu S, Peterson PK, Thayer SA (2000). Beta-chemokines and human immunodeficiency virus type-1 proteins evoke intracellular calcium increases in human microglia. Neurosci 98: 191–199.
  • Herbein G, Mahlknecht U, Batliwalla F, GregersenP, Pappas T, Butler J, O'Brien WA, Verdin E (1998). Apoptosis of CD8+ T cells is mediated by macrophages through inter-action of HIV gp120 with chemokine receptor CXCR4. Nature 395: 189–194.
  • HesselgesserJ, Horuk R (1999). Chemokine and chemokine receptor expression in the c entr al nervous system. J Ne u-rovirol 5: 13–26.
  • Hoffman TL, LaBranche CC, Zhang W, Canziani G, Robinson J, Chaiken I, Hoxie JA, Doms RW (1999). Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein. Proc Nat] Acad Sci USA 96: 6359–6364.
  • Itoh T, Itoh A, Horiuchi K, Pleasure D (1998). AMPA receptor-mediated excitotoxicity in human NT2-N neu-rons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na±. I Neu-rochem 71: 112–124.
  • Janssen RS, Nwanyanwu OC, Selik RM, Stehr-Green J (1992). Epidemiology of HIV encephalopathy in the United States. Neurol 42: 1472–1476.
  • Kalaria RN (1993). The immunopathology of Alzheimer's disease and some related disorders. Brain Pathol 333–347.
  • Kaul M, Lipton SA (1999). Chemokines and activated macrophages in HIV gp120-induced neuronal apopto-sis. Proc Nat] Acad Sci USA 96: 8212–8216.
  • Kledal TN, Rosenkilde MM, Coulin F, Simmons G, Johnsen AH, Alouani S, Power CA, Luttichau HR, Gerstoft J, Clapham PR, Clark-Lewis I, Wells TNC, Schwartz TWA (1997). Broad-spectrum chemokine antagonist encoded by Kaposi's sarcoma-associated herpesvirus. Science 277: 1656–1659.
  • Koenig S, Gendelman HE, Orenstein JM, Dal Canto MC, Pezeshkpour GH, Yungbluth M, Janotta F, Aksamit A, Martin MA, Fauci AS (1986). Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233: 1089–1093.
  • Kolson DL, Lavi E, Gonzalez-Scarano F (1998). The effects of Human Immunodeficiency Virus in the central ner-vous system. Adv Virus Res 50: 1–47.
  • Kwong PD, Wyatt R, Sattentau QJ, Sodroski J, Hendrickson WA (2000). Oligomeric modeling and electrostatic anal-ysis of the gp120 envelope glycoprotein of human im-munodeficiency virus. I Virol 74: 1961–1972.
  • Lee B, Sharron M, Montaner LJ, Weissman D, Doms RW (1999). Quantification of CD4, CCR5, and CXCR4 lev-els on lymphocyte subsets, dendritic cells, and differen-tially conditioned monocyte-derived macrophages. Proc Nat] Acad Sci USA 96: 5215–5220.
  • Liu QH, Williams DA, McManus C, Baribaud F, Doms RW, Schols D, De Clercq E, Kotlikoff MI, Collman RG, Freedman BD (2000). HIV-1 gp120 and chemokines ac-tivate ion channels in primary macrophages through CCR5 and CXCR4 stimulation. Proc Nat] Acad Sci USA 97: 4832–4837.
  • Ma M, Kersten DB, Kamrud KJ, Wool-Lewis RJ, Schmaljohn C, Gonzalez-Scarano F (1999). Murine leukemia virus pseudotypes of La Crosse and Hantaan Bunyaviruses: a system for analysis of cell tropism. Virus Res 64: 23–32.
  • Maciejewski-Lenoir D, Chen S, Feng L, Maki R, Ba-con KB (1999). Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia. I Immunol 163: 1628–1635.
  • Madani N, Kozak SL, Kavanaugh MP, Kabat D (1998). gp120 envelope glycoproteins of human immunodeficiency viruses competitively antagonize signaling by corecep-tors CXCR4 and CCR5. Proc Nat] Acad Sci USA 95: 8005–8010.
  • McArthur JC, Seines OA, Glass JD, Hoover DR, Bacellar H(1994). HIV dementia: incidence and risk factors. In HIV AIDS and the brain. Price RW, Perry SW (eds). New York: Raven Press, Ltd, pp 251–272.
  • Medana IM, Hunt NH, Chan-Ling T (1997). Early activation of microglia in the pathogenesis of fatal murine cerebral malaria. Glia 19: 91–103.
  • Meucci O, Fatatis A, Simen AA, Bushell TJ, Gray PW, Miller RJ (1998). Chemokines regulate hippocampal neuronal signaling and gp120 neurotoxicity. Proc Nat] Acad Sci USA 95: 14500–14505.
  • Meucci O, Miller RJ (1996). gp120-induced neurotoxicity in hippocampal pyramidal neuron cultures: protective action of TGF-betat J Neurosci 16: 4080–4088.
  • Moore JP, Thali M, Vignaux F, Poon S-W, Charles M, Sun B, Durda PJ, Akerblom L, Alkhatib G, Ho DD, Sattentau QJ, Sodroski J (1993). Immunochemical analysis of the gp120 surface glycoprotein of human immunodefi-ciency virus type 1: probing the structure of the C4 and V4 domains and the interaction of the C4 domain with V3 loop. I Virol 67: 4785–4796.
  • Murdoch C, Finn A (2000). Chemokine receptors and their role in inflammation and infectious diseases. Blood 95: 3032–3043.
  • Nath A, Haughey NJ, Jones M, Anderson C, Bell JE, Geiger JD (2000). Synergistic neurotoxicity by human immun-odeficiency virus proteins tat and gp120: protection by memantine. Ann Neurol 47: 186–194.
  • Nishiyori A, Minami M, Ohtani Y, Takami S, Yamamoto J, Kawaguchi N, Kume T, Akaike A, Satoh M (1998). Local-ization of fractalkine and CX3CR1 mRNAs in rat brain: does fractalkine play a role in signaling from neuron to microglia? FEBS Lett 429: 167–172.
  • Pauli G, Hausmann E, Weiss R, Clapham P, Schneider J, Hunsmann, Gallo RC, Daniel MD, Koch MA, Gelderblom H(1987). LAV/HTLV-III: fine-structure analysis, local-ization of structural proteins, and detection of envelope antigens by patient sera. Hamatol Bluttransfusion 31: 407–409.
  • Porwit A, Parravicini C, Petren AL, Barkhem T, Costanzi G, Josephs S, Biberfeld P (1989). Cell association of HIV in AIDS-related encephalopathy and dementia. APMIS 97: 79–90.
  • Pulliam L, Gascon R, Stubblebine M, McGuire D, McGrath MS (1997). Unique monocyte subset in patients with AIDS dementia. Lancet 349: 692–695.
  • Schneider J, Kaaden O, Copeland TD, Oroszlan S, Hunsmann G (1986). Shedding and interspecies type sero-reactivity of the envelope glycopolypeptide gp120 of the human immunodeficiency virus. I Gen Virol 67: 2533–2538.
  • Sciorati C, Rovere P, Ferrarini M, Paolucci C, Heltai S, Vaiani R, Clementi E, Manfredi AA (1999). Generation of nitrix oxide by the inducible nitric oxide synth-ease protects gamma delta T cells from Mycobacterium tuberculosis-induced apoptosis. I Immunol 163: 1570–1576.
  • Soontorrmiyomij V, Wang G, Pittman CA, Wiley CA, Achim CL (1998). Expression of brain-derived neuro-trophic factor protein in activated microglia of human immunodeficiency virus type 1 encephalitis. Neu-ropathol App] Neurobiol 24: 453–460.
  • Stoll G, Jander S (1999). The role of microglia and macrophages in the pathophysiology of the CNS. Prog Neurobiol 58: 233–247.
  • Strizki JM, Albright AV, Sheng H, O'Connor M, Perrin L, Gonzalez-Scarano F (1996). Infection of primary human microglia and monocyte -derived macrophages with human immunodeficiency virus type 1 isolates: ev-idence of differential tropism. I Virol 70: 7654–7662.
  • Thali M, Furman C, Helseth E, Repke H, Sodroski J (1992). Lack of correlation between soluble CD4-induced shedding of the human immunodeficiency virus type 1 exterior envelope glycoprotein and subsequent mem-brane fusion events. I Virol 66: 5516–5524.
  • Thali M, Moore JP, Furman C, Charles M, Ho DD, Robinson J, Sodroski J (1993). Characterization of conserved human immunodeficiency virus type 1 gp120 neutralization epitopes exposed upon gp120-CD4 binding. I Virol 67: 3978–3988.
  • Tyor WR, Glass JD, Baumrind N, McArthur JC, Driffm JW, Becker PS, Griffin DE (1993). Cytokine expression of macrophages in HIV-1-associated vacuolar myelopathy. Neurol 43: 1002–1009.
  • Vodicka MA, Goh WC, Wu LI, Rogel ME, Bartz SR, Schweickart VL, Raport CJ, Emerman M (1997). Indi-cator cell lines for detection of primary strains of hu-man and simian immunodeficiency viruses. Virology 233: 193–198.
  • Weis S, Neuhaus B, Mehraein P (1994). Activation of mi-croglia in HIV-1 infected brains is not dependent on the presence of HIV-1 antigens. Neuroreport 5: 1516–6.
  • Weiss CD, Levy JA, White JM (1990). Oligomeric organiza-tion of gp120 on infectious human immunodeficiency virus type 1 particles. I Virol 64: 5674–5677.
  • Weissman D, Rabin RL, Arthos J, Rubbert A, Dybul M, Swofford R, Venkatesan S, Farber JM, Fauci AS (1997). Macrophage-tropic HIV and SW envelope proteins in-duce a signal through the CCR5 chemokine receptor. Nature 389: 981–985.
  • Wiley CA, Schrier RD, Nelson JA, Lampert PW, Oldstone MBA (1986). Cellular localization of human immunod-eficiency virus infection within the brains of acquired immune deficiency syndrome patients. Proc Nat] Acad Sci USA 83: 7089–7093.
  • Wu L, Gerard NP, Wyatt R, Choe H, Parolin C, Ruffing N, Borsetti A, Cardoso AA, DesjardinE, Newman W, Gerard C, Sodroski J (1996). CD4-induced interaction of primary HIV-1gp120 glycoproteins with the chemokine receptor CCR-5. Nature 384: 179–187.
  • Wyatt R, Moore J, Accola M, Desjardin E, Robinson J, Sodroski J (1995). Involvement of the V1/V2 variable loop structure in the exposure of Human Immunodefi-ciency Virus type 1 gp120 epitopes induced by receptor binding. I Virol 69: 5723–5733.
  • Zhang GX, Baker CM, Kolson DL, Rostami AM (2000). Chemokines and chemokine receptors in the pathogen-esis of multiple sclerosis. Mult Scler 6: 3–13.

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